A Simulation of the Effects of Diffusion on Hyperpolarized [1-13C]-Pyruvate Signal Evolution

Authors: Patel, R.J.S., Harlan, C.J., Fuentes, D.T., Bankson, J.A.

Source: IEEE Transactions on Biomedical Engineering IEEE Trans. Biomed. Eng. Biomedical Engineering, IEEE Transactions on. 70(10):2905-2913 Oct, 2023

Population Pharmacokinetics-Based Evaluation of Ceftazidime-Avibactam Dosing Regimens in Critically and Non-Critically Ill Patients With Carbapenem-Resistant Klebsiella pneumoniae

Authors: Chen Y, Chen B, Huang Y, Li X, Wu J, Lin R, Chen M, Liu M, Qiu H, Cheng Y

Source: Infection and Drug Resistance, Vol Volume 18, Pp 941-955 (2025)

Subject Terms: ceftazidime-avibactam, pharmacokinetic modeling, renal function, monte carlo simulation, dose optimization, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://www.dovepress.com/population-pharmacokinetics-based-evaluation-of-ceftazidime-avibactam--peer-reviewed-fulltext-article-IDR; https://doaj.org/toc/1178-6973

Access URL: https://doaj.org/article/2a166605828f4b61842b0de4ce949de2

Pharmacokinetic Modeling of the Second-Wave Phenomenon in Nanobubble-Based Contrast-Enhanced Ultrasound

Authors: Chen, C., Perera, R., Kolios, M.C., Wijkstra, H., Exner, A.A., Mischi, M., Turco, S.

Source: IEEE Transactions on Biomedical Engineering IEEE Trans. Biomed. Eng. Biomedical Engineering, IEEE Transactions on. 70(1):42-54 Jan, 2023

PBPK Model Simulation study on Impact of Captrophil for Renal Impairment patients(RI)

Authors: Hexy, Mary, Jose, Subha Hency, Ambikadevi, B.

Source: 2022 IEEE 7th International conference for Convergence in Technology (I2CT) Convergence in Technology (I2CT), 2022 IEEE 7th International conference for. :1-4 Apr, 2022

Relation: 2022 IEEE 7th International conference for Convergence in Technology (I2CT)

A novel kinetic model estimating the urea concentration in plasma during non-invasive sweat-based monitoring in hemodialysis

Authors: Xiaoyu Yin, Sophie Adelaars, Elisabetta Peri, Eduard Pelssers, Jaap Den Toonder, Arthur Bouwman, Daan Van de Kerkhof, Massimo Mischi

Source: Frontiers in Physiology, Vol 16 (2025)

Subject Terms: kidney failure, end-stage renal disease, patient monitoring, pharmacokinetic modeling, inverse modeling, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2025.1547117/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/f08317a53ff34b7f9db8e7331a4518d9

Amphotericin B tissue penetration and pharmacokinetics in healthy and Candida albicans-infected rats: insights from microdialysis and population modeling

Authors: Valdeene Vieira Santos, Laiz Campos Pereira, Jackeline Marley Santos de Araújo, Matheus Antônio da Hora Borges, Carolina Magalhães Brandão, Luisa Oliveira Santos, Cristiane Flora Villarreal, Francine Johansson Azeredo

Source: Frontiers in Pharmacology, Vol 15 (2025)

Subject Terms: Amphotericin B, Candida albicans, population pharmacokinetic modeling, microdialysis, rats, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1515462/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/3e790bda6d3643ebbda33ea74003a6fc

Therapeutic Drug Monitoring and Pharmacokinetics-Based Individualization of Drug Therapy

Contributors: Vasarhelyi, Barna, Karvaly, Gellért Balázs

Subject Terms: ganciclovir, lung transplant recipients, cystic fibrosis, therapeutic drug monitoring, covariates, haloperidol, pharmacokinetics, delirium, critical ill, ICU, dapagliflozin, linagliptin, fixed-dose combination products, bioequivalence, busulfan, sulfolane, myelofibrosis, population pharmacokinetics, heart transplantation, acute rejection, tacrolimus, endomyocardial biopsies, pharmacokinetic interactions, heart transplant, precision medicine, clinical practice, gentamicin, population pharmacokinetic modeling, external evaluation, model re-estimation, dosing nomogram, long-acting antiretroviral therapy, cabotegravir, rilpivirine, pharmacokinetic simulation, TDM, plasma level, PK/PD, dose–effect relationship, LC–MS/MS, CFTR modulators, caftor, ivacaftor, lumacaftor, tezacaftor, elexacaftor, population pharmacokinetic, rivaroxaban, atrial fibrillation, direct oral anticoagulants, Thai patient, tobramycin, model-informed precision dosing, dalbavancin, long-acting, Gram-positive, osteoarticular infections, laparoscopic sleeve gastrectomy, omeprazole, modeling and simulation, obesity, treatment efficacy, medication adherence, schizophrenia spectrum and other psychotic disorders, bipolar and related disorders, depressive disorder, cefiderocol, antibiotics, drug monitoring, isavuconazole, pediatric, pharmacodynamics, Bayesian, fungal infection, outcomes, oral anticancer drugs, oncology, imatinib, precision pharmacotherapy, cerebrospinal fluid, methotrexate, children, acute lymphoid leukemia, external validation, non-infectious uveitis (NIU), therapeutic drug monitoring (TDM), pharmacogenetics, biological therapy, limited sampling strategies, population pharmacokinetic modelling, semi-parametric simulation, robustness, area under the curve, AUC, glomerular filtration rate, GFR, tuberculosis, rifampicin, dried blood spots, limited-sampling strategy, pharmacokinetic boosting, pharmacokinetic enhancement, ritonavir, cobicistat, kinase inhibitors, small molecule kinase inhibitors, critical illness, sepsis, kidney injury, biomarkers, pediatric pharmacology, Bayesian estimation, piperacillin, tazobactam, nonparametric adaptive grid, Bayesian models, intensive care, Medicine and Nursing, Pharmacology

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/143737
https://mdpi.com/books/pdfview/book/9781

Organic cation transporters 2: Structure, regulation, functions, and clinical implications

Authors: Ailabouni, Anoud, Prasad, Bhagwat ^∗

Source: In Drug Metabolism and Disposition March 2025 53(3)

Compare and PASS − Fast screening of oral dosage forms for bioequivalence probability with the COMPASS software

Authors: Danielak, Dorota ^{a, ⁎, 1}, Myslitska, Daria ^a, Winiarski, Maciej ^b, Paszkowska, Jadwiga ^a, Dobosz, Justyna ^a, Staniszewska, Marcela ^a, Smoleński, Michał ^a, Banach, Grzegorz ^a, Garbacz, Grzegorz ^a, Sarcevica, Inese ^c, McAllister, Mark ^c, Arjmandi-Tash, Omid ^d, Romański, Michał ^{e, 1}

Source: In International Journal of Pharmaceutics 10 February 2025 670

Heterotropic allosteric modulation of CYP3A4 in vitro by progesterone: Evidence for improvement in prediction of time-dependent inhibition for macrolides

Authors: Rougée, Luc R.A. ^∗, Hegde, Pooja V., Shin, Kaitlin, Abraham, Trent L., Bell, Alec, Hall, Stephen D.

Source: In Drug Metabolism and Disposition January 2025 53(1)

Towards the understanding of the IVPT results variability—Development, verification and validation of the PBPK model of caffeine in vitro human skin permeation

Authors: Krumpholz, Laura ^{a, b}, Polak, Sebastian ^{c, d}, Wiśniowska, Barbara ^{a, ⁎}

Source: In European Journal of Pharmaceutical Sciences 1 January 2025 204

Pharmacokinetic modeling of sulfamethoxazole-trimethoprim and sulfadiazine-trimethoprim combinations in broilers

Authors: Marine Boulanger, Jean-François Taillandier, Jérôme Henri, Mathias Devreese, Siegrid De Baere, Aude A. Ferran, Alexis Viel

Source: Poultry Science, Vol 103, Iss 11, Pp 104200- (2024)

Subject Terms: sulfonamide, trimethoprim, combination, dosage regimen, population pharmacokinetic modeling, Animal culture, SF1-1100

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S003257912400779X; https://doaj.org/toc/0032-5791

Access URL: https://doaj.org/article/263c097c5d2e46ffb1f7e45ffffea1eb

Dose, exposure, and treatment regimen of intravenous immunoglobulin G in multifocal motor neuropathy

Authors: Zhaoyang Li, Stefan Roepcke, Ryan Franke, Leman Yel

Source: Frontiers in Neurology, Vol 15 (2024)

Subject Terms: intravenous immunoglobulin, multifocal motor neuropathy, immunoglobulin, population pharmacokinetic modeling, dose-exposure relationship, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2024.1478419/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/14cb03d93729418393dd4776a8b554e8

PBPK-based translation from preclinical species to humans for the full-size IgG therapeutic efalizumab

Authors: Maria Franz, Ravi Kumar Jairam, Lars Kuepfer, Nina Hanke

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: efalizumab, raptiva, cross-species translation, physiologically based pharmacokinetic modeling (PBPK), monoclonal antibody (mAb), target mediated drug disposition (TMDD), Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1418870/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/584054ca9bd24dc6b481a8570bbae847

Drug–drug interactions between letermovir and tacrolimus in Japanese renal transplant recipients simulated using a physiologically based pharmacokinetic model

Authors: Takumi Maruyama, Hidefumi Kasai, Yutaka Fukaya, Mitsuru Shiokawa, Toshimi Kimura, Yukihiro Hamada

Source: Frontiers in Microbiology, Vol 15 (2024)

Subject Terms: physiologically based pharmacokinetic modeling, drug–drug interaction, letermovir, tacrolimus, renal transplantation, Japanese population, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2024.1480874/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/8f157bb039a14f76bfc16141420e7b59

Immunomodulatory Effects of Atractylodes lancea in Healthy Volunteers with Dosage Prediction for Cholangiocarcinoma Therapy: A Modelling Approach

Authors: Teerachat Saeheng, Juntra Karbwang, Kesara Na-bangchang

Source: Pharmaceuticals, Vol 18, Iss 2, p 198 (2025)

Subject Terms: pharmacokinetics, atractylodin, immunomodulatory, physiologically based pharmacokinetic model, PBPK, pharmacokinetic modeling, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/18/2/198; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/433be04f6862444ba3921be5d711ea6a

Whole-Body Physiologically Based Pharmacokinetic Modeling of GalNAc-Conjugated siRNAs

Authors: Emilie Langeskov Salim, Kim Kristensen, Erik Sjögren

Source: Pharmaceutics, Vol 17, Iss 1, p 69 (2025)

Subject Terms: siRNA, physiologically based pharmacokinetic modeling, PK-Sim, ASGPR, RISC, GalNAc, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/17/1/69; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/0827e8c2d925411b9765d742aeff88e5

Population pharmacokinetic modeling study and discovery of covariates for the antidepressant sertraline, a serotonin selective reuptake inhibitor

Authors: Jang, Ji-Hun ^a, Jeong, Seung-Hyun ^{b, c, ⁎}

Source: In Computers in Biology and Medicine December 2024 183

Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data

Authors: Athanasios Chamzas, Eglis Tellez, Andrew SyBing, Jogarao V. S. Gobburu, Mathangi Gopalakrishnan

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: tacrolimus, renal transplant, hispanic population, population pharmacokinetic modeling, real world data, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1443988/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/da9ce3aecc11421e8cb3bbd54e1a6cdb

Getting the dose right using physiologically-based pharmacokinetic modeling: dexamethasone to prevent post-extubation stridor in children as proof of concept

Authors: Joyce E. M. van der Heijden, Marika de Hoop-Sommen, Noa Hoevenaars, Jolien J. M. Freriksen, Koen Joosten, Rick Greupink, Saskia N. de Wildt

Source: Frontiers in Pediatrics, Vol 12 (2024)

Subject Terms: dexamethasone, modeling & simulation, pediatrics, pharmacokinetics, physiologically-based pharmacokinetic modeling, special populations, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2024.1416440/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/171193c1949d4eec9eea2f643a4373e1