Feasibility of Serum Peroxiredoxin 2 as a Biochemical Indicator for Reflecting Severity and Prognosticating Stroke-Associated Pneumonia, Early Neurological Deterioration and Poor Neurological Outcomes in Acute Supratentorial Intracerebral Hemorrhage: An Observational Analytical Clinical Study

Authors: Zhang C, Zhang G, Ye Z, Hu G, Ge S, Luo K, Li Z

Source: Neuropsychiatric Disease and Treatment, Vol Volume 21, Pp 621-640 (2025)

Subject Terms: peroxiredoxin 2, intracerebral hemorrhage, outcome, severity, biomarkers, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.dovepress.com/feasibility-of-serum-peroxiredoxin-2-as-a-biochemical-indicator-for-re-peer-reviewed-fulltext-article-NDT; https://doaj.org/toc/1178-2021

Access URL: https://doaj.org/article/4689094c937c46ab8a3ef15f514dffb3

Peroxiredoxin 2 regulates DAF-16/FOXO mediated mitochondrial remodelling in response to exercise that is disrupted in ageing

Authors: Qin Xia, Penglin Li, José C. Casas-Martinez, Antonio Miranda-Vizuete, Emma McDermott, Peter Dockery, Katarzyna Goljanek-Whysall, Brian McDonagh

Source: Molecular Metabolism, Vol 88, Iss , Pp 102003- (2024)

Subject Terms: Ageing, Peroxiredoxin 2, Exercise, C.elegans, Mitochondrial ER contact sites, DAF-16, Internal medicine, RC31-1245

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Relation: http://www.sciencedirect.com/science/article/pii/S2212877824001340; https://doaj.org/toc/2212-8778

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The rheumatoid arthritis drug Auranofin targets peroxiredoxin 1 and peroxiredoxin 2 to trigger ROS-endoplasmic reticulum stress axis-mediated cell death and cytoprotective autophagy

Authors: Yang, Wenyue ^{a, 1}, Zhu, Zhou ^{b, 1}, Zhou, Chaohua ^{b, 1}, Chen, Junhui ^{b, 1}, Ou, Jinhuan ^b, Tong, Haibo ^b, Iyaswamy, Ashok ^{c, d}, Chen, Peng ^e, Wei, Xu ^f, Yang, Chuanbin ^b, Xiao, Wei ^{g, ⁎}, Wang, Jigang ^{a, b, g, h, ⁎⁎}, Zhang, Wei ^{g, ⁎⁎⁎}

Source: In Free Radical Biology and Medicine June 2025 233:1-12

MSC-EV-transmitted HSPA8 alleviates cisplatin-induced ovotoxicity by regulating the MGARP/PRDX2 axis

Authors: Zhang, Shenghui ^{a, b, c, 1}, Song, Haofeng ^{a, 1}, Chang, Mengyuan ^{a, f, 1}, Lu, Yilin ^a, Liu, Shuyao ^e, Wu, Jie ^{a, f}, Liu, Qin ^{a, b}, Pan, Ying ^e, Du, Jiang ^a, Yahaya, Badrul Hisham ^{d, ⁎}, Liu, Yanli ^{a, b, ⁎⁎}, Lin, Juntang ^{a, b, ⁎⁎}

Source: In International Journal of Biological Macromolecules April 2025 304 Part 2

Choroid plexus immune cell response in murine hydrocephalus induced by intraventricular hemorrhage

Authors: Yingfeng Wan, Xiongjie Fu, Tianjie Zhang, Ya Hua, Richard F. Keep, Guohua Xi

Source: Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-15 (2024)

Subject Terms: Hydrocephalus, Intraventricular hemorrhage, iron, Peroxiredoxin 2, Choroid plexus, Immune cells, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/8e9d7a4c24334d47813b49c751cf6712

Degradation of band3 and PRDX2 in erythrocytes during severe acute GVHD

Authors: Masayuki Nagasawa

Source: eJHaem, Vol 4, Iss 2, Pp 459-462 (2023)

Subject Terms: band3, calpain‐1, erythrocytes, GVHD, oxidative stress, peroxiredoxin 2, Diseases of the blood and blood-forming organs, RC633-647.5

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Relation: https://doaj.org/toc/2688-6146

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Catalase, Glutathione Peroxidase, and Peroxiredoxin 2 in Erythrocyte Cytosol and Membrane in Hereditary Spherocytosis, Sickle Cell Disease, and β-Thalassemia

Authors: Daniela Melo, Fátima Ferreira, Maria José Teles, Graça Porto, Susana Coimbra, Susana Rocha, Alice Santos-Silva

Source: Antioxidants, Vol 13, Iss 6, p 629 (2024)

Subject Terms: catalase, glutathione peroxidase, peroxiredoxin 2, hereditary spherocytosis, sickle cell disease, β-thalassemia, Therapeutics. Pharmacology, RM1-950

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Relation: https://www.mdpi.com/2076-3921/13/6/629; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/4c38c1a887294876a4a8f973eb7f78dd

Modeling Melanoma Heterogeneity In Vitro: Redox, Resistance and Pigmentation Profiles

Authors: Larissa Anastacio da Costa Carvalho, Isabella Harumi Yonehara Noma, Adriana Hiromi Uehara, Ádamo Davi Diógenes Siena, Luciana Harumi Osaki, Mateus Prates Mori, Nadja Cristhina de Souza Pinto, Vanessa Morais Freitas, Wilson Araújo Silva Junior, Keiran S. M. Smalley, Silvya Stuchi Maria-Engler

Source: Antioxidants, Vol 13, Iss 5, p 555 (2024)

Subject Terms: melanoma, heterogeneity, pigmentation, peroxiredoxin 1, peroxiredoxin 2, BRAFi resistance, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/5/555; https://doaj.org/toc/2076-3921

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Glucose-6-Phosphate Dehydrogenase Deficiency and Neonatal Hyperbilirubinemia: Insights on Pathophysiology, Diagnosis, and Gene Variants in Disease Heterogeneity

Authors: Heng Yang Lee, Azlin Ithnin, Raja Zahratul Azma, Ainoon Othman, Armindo Salvador, Fook Choe Cheah

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: molecular screening, bilirubin, favism, hemolytic anemia, neonatal jaundice, peroxiredoxin 2, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.875877/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/56271da16c9a418998f80a44c5890c49

Tyrosine kinase inhibitors modulate the expression of peroxiredoxins 1 and 2 in chronic myeloid leukemia cells

Authors: Kazama, Hiroshi ^{a, b, ⁎}, Wang, Yan-Hua ^b, Tanaka, Junji ^b

Source: In Leukemia Research Reports 2025 23

Expression of thioredoxin 1 and peroxiredoxins in squamous cervical carcinoma and its predictive role in NACT

Authors: Haiyan Zhu, Xuejiao Tao, Lulu Zhou, Bo Sheng, Xuejie Zhu, Xueqiong Zhu

Source: BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)

Subject Terms: Thioredoxin 1, Peroxiredoxin 1, Peroxiredoxin 2, Neoadjuvant chemotherapy, Cervical squamous cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-019-6046-x; https://doaj.org/toc/1471-2407

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Hyperoxidized Peroxiredoxin 2 Is a Possible Biomarker for the Diagnosis of Obstructive Sleep Apnea

Authors: Shin Koike, Haruka Sudo, Satori Turudome, Masako Ueyama, Yoshiaki Tanaka, Hiroshi Kimura, Yo-Ichi Ishida, Yuki Ogasawara

Source: Antioxidants, Vol 11, Iss 12, p 2486 (2022)

Subject Terms: peroxiredoxin 2, hyperoxidation, obstructive sleep apnea, biomarker, hypoxia, oxidative stress, Therapeutics. Pharmacology, RM1-950

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Relation: https://www.mdpi.com/2076-3921/11/12/2486; https://doaj.org/toc/2076-3921

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Peroxiredoxin 2 Ameliorates AβO-Mediated Autophagy by Inhibiting ROS via the ROS–NRF2–p62 Pathway in N2a-APP Swedish Cells

Authors: Wei Jin, Min Kyoung Kam, Sung Woo Lee, Young-Ho Park, Hong Jun Lee, Dong-Seok Lee

Source: Antioxidants, Vol 11, Iss 10, p 1889 (2022)

Subject Terms: Alzheimer’s disease, oxidative stress, autophagy, ROS–NRF2–p62 pathway, cell death, peroxiredoxin 2, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/11/10/1889; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/97e981e075944fd1a71def3ff2c89c36

Identification and functional analysis of senescence-associated secretory phenotype of premature senescent hepatocytes induced by hexavalent chromium

Authors: Yu Ma, Yuehui Liang, Ningjuan Liang, Yujing Zhang, Fang Xiao

Source: Ecotoxicology and Environmental Safety, Vol 211, Iss , Pp 111908- (2021)

Subject Terms: Hexavalent chromium [Cr(VI)], Premature senescence, Senescence-associated secretion phenotype (SASP), Alpha-enolase (ENO1), Peroxiredoxin 2 (PRDX2), Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651321000191; https://doaj.org/toc/0147-6513

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PRDX2 Protects Against Atherosclerosis by Regulating the Phenotype and Function of the Vascular Smooth Muscle Cell

Authors: Jing Li, Cong Wang, Wenjing Wang, Lingzi Liu, Qingqing Zhang, Jun Zhang, Bo Wang, Shujing Wang, Li Hou, Chuanzhou Gao, Xiao Yu, Lei Sun

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: peroxiredoxin 2, atherosclerosis, vascular smooth muscle cell, phenotype, MAPK signaling, ROS, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.624796/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/3e3be509674847f9975b008b81e8919b

Peroxiredoxin 2 activates microglia by interacting with Toll-like receptor 4 after subarachnoid hemorrhage

Authors: Yue Lu, Xiang-Sheng Zhang, Zi-Huan Zhang, Xiao-Ming Zhou, Yong-Yue Gao, Guang-Jie Liu, Han Wang, Ling-Yun Wu, Wei Li, Chun-Hua Hang

Source: Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-10 (2018)

Subject Terms: Subarachnoid hemorrhage, Peroxiredoxin 2, Microglial activation, Toll-like receptor 4, Neuronal apoptosis, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12974-018-1118-4; https://doaj.org/toc/1742-2094

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Adaptative Up-Regulation of PRX2 and PRX5 Expression Characterizes Brain from a Mouse Model of Chorea-Acanthocytosis

Authors: Enrica Federti, Alessandro Matte, Veronica Riccardi, Kevin Peikert, Seth L. Alper, Adrian Danek, Ruth H. Walker, Angela Siciliano, Iana Iatcenko, Andreas Hermann, Lucia De Franceschi

Source: Antioxidants, Vol 11, Iss 1, p 76 (2021)

Subject Terms: peroxiredoxin 2, peroxiredoxin 5, neuroinflammation, chorea-acanthocytosis, nilotinib, Lyn, Therapeutics. Pharmacology, RM1-950

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Relation: https://www.mdpi.com/2076-3921/11/1/76; https://doaj.org/toc/2076-3921

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Pharmacological Inhibition of HDAC6 Attenuates NLRP3 Inflammatory Response and Protects Dopaminergic Neurons in Experimental Models of Parkinson’s Disease

Authors: Shaoqi Yan, Xinbing Wei, Wencheng Jian, Yue Qin, Jia Liu, Shaowei Zhu, Fan Jiang, Haiyan Lou, Bin Zhang

Source: Frontiers in Aging Neuroscience, Vol 12 (2020)

Subject Terms: HDAC6, NLRP3, Parkinson’s disease, peroxiredoxin 2, tubastatin A, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnagi.2020.00078/full; https://doaj.org/toc/1663-4365

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A proteomics approach for the development of sarcoma biomarkers

Authors: Tadashi Kondo, Akira Kawai

Source: EuPA Open Proteomics, Vol 4, Iss C, Pp 121-128 (2014)

Subject Terms: Sarcoma, Osteosarcoma, Gastrointestinal stromal tumor, Peroxiredoxin 2, Pfetin, Two-dimensional difference gel electrophoresis, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212968514000439; https://doaj.org/toc/2212-9685

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Irreversible hyperoxidation of peroxiredoxin 2 is caused by tert-butyl hydroperoxide in human red blood cells

Authors: Y.I. Ishida, M. Takikawa, T. Suzuki, M. Nagahama, Y. Ogasawara

Source: FEBS Open Bio, Vol 4, Iss C, Pp 848-852 (2014)

Subject Terms: Peroxiredoxin 2, Oxidative stress, Red blood cell, tert-Butyl hydroperoxide, Hyperoxidation, Biomarker, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211546314000928; https://doaj.org/toc/2211-5463

Access URL: https://doaj.org/article/b572b774ea6d4fbcad374da36132c92d