MGMT unmethylation and high levels of CD47 and TIGIT indicate a poor prognosis in adult diffuse gliomas

Authors: Lingbo Ma, Yi Shi, Chang Li, Bin Deng, Jinfang Jiang, Yuwen Cao, Lianghai Wang, Hongyan Li

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: adult-type diffuse glioma, IDH mutant, pTERT mutation, MGMT methylation, CD47, TIGIT, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1323307/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9b7500e74a324ec59816b44d9f14d9c5

Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival

Authors: Azadeh Ebrahimi, Andrey Korshunov, Guido Reifenberger, David Capper, Joerg Felsberg, Elena Trisolini, Bianca Pollo, Chiara Calatozzolo, Marco Prinz, Ori Staszewski, Leonille Schweizer, Jens Schittenhelm, Patrick N. Harter, Werner Paulus, Christian Thomas, Patricia Kohlhof-Meinecke, Marcel Seiz-Rosenhagen, Till Milde, Belén M. Casalini, Abigail Suwala, Annika K. Wefers, Annekathrin Reinhardt, Philipp Sievers, Christof M. Kramm, Nima Etminam, Andreas Unterberg, Wolfgang Wick, Christel Herold-Mende, Dominik Sturm, Stefan M. Pfister, Martin Sill, David T. W. Jones, Daniel Schrimpf, David E. Reuss, Ken Aldape, Zied Abdullaev, Felix Sahm, Andreas von Deimling, Damian Stichel

Source: Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-10 (2022)

Subject Terms: Pleomorphic xanthoastrocytoma, Ganglioglioma, Epithelioid glioblastoma, BRAF V600E, pTERT mutation, DNA methylation array profiling, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/3e45563738ca4626aad3e030dbd8c07b

Molecular Aberrations Stratify Grade 2 Astrocytomas Into Several Rare Entities: Prognostic and Therapeutic Implications

Authors: Valeria Internò, Giacomo Triggiano, Pierluigi De Santis, Luigia Stefania Stucci, Marco Tucci, Camillo Porta

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: diffuse low-grade gliomas, prognostic molecular stratification, IDH-wt grade 2 astrocytoma, pTERT mutation, EGFR amplification, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.866623/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/f25a001b23594a86b5e680c666d460b4