Bupleuri Radix Ameliorates Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Modulation of Tight Junction Protein Expression and Inhibition of Nuclear Factor-κB Activation

Authors: Min Yeong Kim, Eun Jin Bang, Yung Hyun Choi, Su Hyun Hong

Source: Journal of Pharmacopuncture, Vol 28, Iss 1, Pp 57-68 (2025)

Subject Terms: bupleuri radix, human umbilical vein endothelial cells, tight junction protein, nuclear factor-kappa-b, vascular inflammation, Medicine, Miscellaneous systems and treatments, RZ409.7-999, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.journal-jop.org/journal/view.html?doi=10.3831/KPI.2025.28.1.57; https://doaj.org/toc/2093-6966

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Orientin alleviates chondrocyte senescence and osteoarthritis by inhibiting PI3K/AKT pathway

Authors: Haitao Chen, Siyi Liu, Junwei Xing, Yinxian Wen, Liaobin Chen

Source: Bone & Joint Research, Vol 14, Iss 3, Pp 245-258 (2025)

Subject Terms: osteoarthritis, orientin, chondrocyte senescence, reactive oxygen species, pi3k/akt pathway, chondrocytes, osteoarthritis (oa), rat model, interleukin, osteophytes, cartilage, rna, radiograph, nuclear factor kappa b, anterior cruciate ligament transection (aclt), Diseases of the musculoskeletal system, RC925-935

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Relation: https://doaj.org/toc/2046-3758

Access URL: https://doaj.org/article/5c0acf1a310146b286a23b2e2d7d36a7

Risk factors for non-responsiveness to 5-aminosalicylic acid in patients with ulcerative colitis identified using retrospective clinical study and Mendelian randomization

Authors: Zhi-Ning Ye, Xin-Tian Liu, Yue-Ming Gu, Shu-Xian Mao, Dan-Hong Liang, Kai Zhan, Hao-Qiang Lei, Shao-Gang Huang

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-13 (2025)

Subject Terms: Ulcerative colitis, 5-Aminosalicylic acid, Responsiveness, Allergy, Aspartate aminotransferase-to-alanine aminotransferase ratio, Inhibitor of nuclear factor kappa-B kinase subunit alpha, Medicine, Science

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Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3e0b9cbf5fc547faa6dcc031b69efb8e

Targeting skeletal interoception: a novel mechanistic insight into intervertebral disc degeneration and pain management

Authors: Houcheng Zhu, JianHang Ren, Xiangjin Wang, Wenjing Qin, Yong Xie

Source: Journal of Orthopaedic Surgery and Research, Vol 20, Iss 1, Pp 1-19 (2025)

Subject Terms: Intervertebral disc degeneration, Interception, Skeletal interoception, Prostaglandin E2, Nuclear factor kappa B, Wnt/β-catenin, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

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Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/9e89359289644a658b16854b6c28c88f

Skullcapflavone II suppresses TGF-β-induced corneal epithelial mesenchymal transition in vitro

Authors: Meng-Xi Li, Zhen Zhang, Yue Zhang, Fan-Ru Zhao, Yu-Fan Li, Yu-Fei Dang, Yang-Yang Yue, Li Li

Source: International Journal of Ophthalmology, Vol 18, Iss 2, Pp 209-215 (2025)

Subject Terms: skullcapflavone ii, epithelial-mesenchymal transition, transforming growth factor, nuclear factor kappa-b, human corneal epithelial cells, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://ies.ijo.cn/en_publish/2025/2/20250202.pdf; https://doaj.org/toc/2222-3959; https://doaj.org/toc/2227-4898

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Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice

Authors: Yanli Zhang, Tian Li, Jie Miao, Zhina Zhang, Mingxuan Yang, Zhuoran Wang, Bo Yang, Jiawei Zhang, Haiting Li, Qiang Su, Junhong Guo

Source: Neural Regeneration Research, Vol 20, Iss 2, Pp 533-547 (2025)

Subject Terms: alzheimer’s disease, amyloid-β, app/ps1 mice, cerebrovascular endothelial cells, cognitive deficits, gamma-glutamyl transferase 5, neurovascular unit, nuclear factor‐kappa b, synaptic plasticity, β-site app cleaving enzyme 1, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://journals.lww.com/10.4103/NRR.NRR-D-23-01525; https://doaj.org/toc/1673-5374; https://doaj.org/toc/1876-7958

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Effects of Aerobic Exercise and Stem Cell Injection on the Expression of NF-κB and MMP1 Genes in the Knee Cartilage of Male Rat Models of Osteoarthritis

Authors: Hamidraza Sharifi, Zaher Etemad, Kamal Azizbeigi, Parvin Farzanegi

Source: مجله علوم پزشکی فیض (پیوسته), Vol 28, Iss 6, Pp 595-602 (2024)

Subject Terms: nuclear factor kappa b (nf-κb), matrix metalloproteinase-1 (mmp1), mesenchymal stem cells, osteoarthritis, aerobic exercise, Medicine

File Description: electronic resource

Relation: http://feyz.kaums.ac.ir/article-1-5124-en.pdf; https://doaj.org/toc/3060-5806; https://doaj.org/toc/3060-5814

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Structural Characterization of Polygonum divaricatum L. Polysaccharide and Its Inhibitory Effect on Lipopolysaccharide-Induced Inflammation in RAW264.7 Cells

Authors: CUI Yanyan, YUAN Yongxu, GUO Mingkun, HE Wenbing, LI Ming, PEI Shichun, LI Dajun

Source: Shipin Kexue, Vol 45, Iss 24, Pp 128-138 (2024)

Subject Terms: polygonum divaricatum l. polysaccharide, lipopolysaccharide, raw264.7 cells, inflammation, mitogen-activated protein kinases/nuclear factor kappa b signaling pathway, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-24-015.pdf; https://doaj.org/toc/1002-6630

Access URL: https://doaj.org/article/67ae35e7ef1d464e84fdc16390b8e2cf

High molecular weight hyaluronic acid alleviates ovariectomy-induced bone loss in mice

Authors: Khangarid Tenger, Keiichiro Komori, Ami Maehara, Kyosuke Miyazaki, Eriko Marukawa, Toshitaka Yoshii, Kunikazu Tsuji

Source: BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-13 (2024)

Subject Terms: Hyaluronic acid, Osteoporosis, Ovariectomy, Receptor activator of nuclear factor kappa-B ligand, Diseases of the musculoskeletal system, RC925-935

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Relation: https://doaj.org/toc/1471-2474

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Fluoxetine inhibited RANKL-induced osteoclastic differentiation in vitro

Authors: Zhang Jing-wen, Zhao Fang-bing, Ma Bing’er, Shen Xiao-qing, Geng Yuan-ming

Source: Open Medicine, Vol 19, Iss 1, Pp 573-81 (2024)

Subject Terms: osteoclast, receptor activator of nuclear factor kappa-b ligand, selective serotonin reuptake inhibitor, fluoxetine, orthodontic tooth movement, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2391-5463

Access URL: https://doaj.org/article/c0bcd5517a41488daa160b78f7ac0f40

Melittin ameliorates schistosomiasis-induced liver fibrosis by suppressing signal transducer and activator of transcription 3 and nuclear factor kappa B

Authors: Ola I. Rozik, Manal M. Hussein, Ahmed S. El-elebiarie, Soad Nady

Source: Journal of the Arab Society for Medical Research, Vol 19, Iss 2, Pp 200-210 (2024)

Subject Terms: anti-inflammatory, liver fibrosis, melittin, nuclear factor kappa b, signal transducer and activator of transcription 3, Medicine

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Relation: https://journals.lww.com/10.4103/jasmr.jasmr_23_24; https://doaj.org/toc/1687-4293

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Differential expression of phosphoinositide 3-kinase/protein kinase B and Toll-like receptor/nuclear factor kappa B signaling pathways in experimental obesity Wistar rat model

Authors: Song Liya, Li Lihua

Source: Open Life Sciences, Vol 19, Iss 1, Pp 3898-918 (2024)

Subject Terms: obesity rat model, high-fat diet, phosphatidylinositol-3-kinase/protein kinase b, toll-like receptor/nuclear factor kappa b, differences, expression, Biology (General), QH301-705.5

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Relation: https://doaj.org/toc/2391-5412

Access URL: https://doaj.org/article/7d247e0acfe7428694e97dc949ffff35

Evaluation of the effect of phellodendrin application on rats creating an experimental model of non-compression lumbar disc herniation on the NF-κB-related inflammatory signaling pathway

Authors: Panlin Tan, Jianbing Mei, Dong Wang

Source: Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-10 (2024)

Subject Terms: Non-compression lumbar disc herniation, Phellodendrine, Nuclear factor-kappa B, Tumor necrosis factor-alpha, Interleukin-1 beta, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

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Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/c15487372ef2449292c8171e373bd126

Resveratrol treats peri-implantitis in mice via inhibiting the MAPKs/NF-κB signaling pathway

Authors: LIU Senqing, ZHANG Hua, CHEN Yanyan, HE Haipeng, HUANG Jiamin, YUAN Jingyi, HU Tianyong, DU Ruitian

Source: 口腔疾病防治, Vol 32, Iss 11, Pp 845-852 (2024)

Subject Terms: peri-implantitis, resveratrol, animal model, p38 mitogen activated protein kinase, nuclear factor kappa-b, Medicine

File Description: electronic resource

Relation: https://www.kqjbfz.com/fileup/2096-1456/PDF/2096-1456（2024）11-0845-08.pdf; https://doaj.org/toc/2096-1456

Access URL: https://doaj.org/article/76807803bfde4e8c9272b70e8d6c7158

Homocysteine aggravates intestinal inflammation through promotion of 5-LOX and COX-2 in IBD

Authors: Jing Wang, Lin Li, Pingbo Chen, Chiyi He, Xiaoping Niu, Qiao Mei

Source: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)

Subject Terms: Cysteinyl leukotrienes, Prostaglandin E2, Nuclear factor kappa B, Inflammatory bowel disease, Homocysteine, 5-Lipoxygenase, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/2741bffc8940412a848a8f360df6b776

Repurposing of sericin combined with dactolisib or vitamin D to combat non-small lung cancer cells through computational and biological investigations

Authors: Maged W. Helmy, Mariam H. Youssef, Imane Yamari, Alaa Amr, Farouzia I. Moussa, Abeer El Wakil, Samir Chtita, Lamia M. El-Samad, Mohamed A. Hassan

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)

Subject Terms: Sericin, Dactolisib, Vitamin D, Lung cancer, Non-small lung cancer cells, Nuclear factor Kappa B (NF-κB), Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/222de78aca1644d8ba512904c839c345

Medicinal Herbal Extracts: Therapeutic Potential in Acute Lung Injury

Authors: Jae-Won Lee, Hee Jae Lee, Seok Han Yun, Juhyun Lee, Hyueyun Kim, Ha Yeong Kang, Kyung-Seop Ahn, Wanjoo Chun

Source: Future Pharmacology, Vol 4, Iss 4, Pp 700-715 (2024)

Subject Terms: acute lung injury, medicinal herbal extract, macrophages, cytokines, nuclear factor kappa B, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2673-9879/4/4/37; https://doaj.org/toc/2673-9879

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The modulatory effects of Lonicera caerulea L. extract and omega-3 on sarcopenia via regulating PI3K and FOXO signaling pathways in rats

Authors: Radwa Wahid Mohamed, Nourhan Gamal El-Rahmany

Source: Journal of HerbMed Pharmacology, Vol 13, Iss 4, Pp 651-658 (2024)

Subject Terms: cathepsin, dexamethasone, muscle atrophy, atrogin-1, haskap berry, nuclear factor kappa b, oxidative damage, Medicine (General), R5-920, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://herbmedpharmacol.com/PDF/jhp-13-651.pdf; https://doaj.org/toc/2345-5004

Access URL: https://doaj.org/article/dc136b9c1afc4da4b9cb1b106c7ea313

Activating Transcription Factor 6 Mediates Inflammation in Experimental Varicocele-Induced Epididymal Epithelial Cells

Authors: Jin YS, Cui YQ, Xu YP, Chen J, Zhang XB, Wang X

Source: Journal of Inflammation Research, Vol Volume 17, Pp 7261-7274 (2024)

Subject Terms: epididymal neutral α-glucosidase, hypoxia, left varicocele, nuclear factor-kappa b p65, nf-κb p65, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/activating-transcription-factor-6-mediates-inflammation-in-experimenta-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Access URL: https://doaj.org/article/2950e1557f5048e0b52667358fcee442

Ginsenoside Rb1 Alleviates DSS-Induced Ulcerative Colitis by Protecting the Intestinal Barrier Through the Signal Network of VDR, PPARγ and NF-κB

Authors: Zhou Y, Xiong X, Cheng Z, Chen Z, Wu S, Yu Y, Liu Y, Chen G, Li L

Source: Drug Design, Development and Therapy, Vol Volume 18, Pp 4825-4838 (2024)

Subject Terms: ginsenoside rb1, ulcerative colitis, intestinal barrier, vitamin d receptor, nuclear factor-kappa b, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/ginsenoside-rb1-alleviates-dss-induced-ulcerative-colitis-by-protectin-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/df6992f2b4bc46e98a6b69b9227e1c1a