A rare case of pediatric T-cell acute lymphoblastic leukemia with myeloid mimicry

Authors: Wenpeng Ni, Ji Liu, Kunyi Deng, Zhouyu Zeng, Qingzhu Kong, Xiaoling Weng

Source: Discover Oncology, Vol 15, Iss 1, Pp 1-9 (2024)

Subject Terms: Acute lymphoblastic leukemia, Granular blasts, KMT2A::AFDN, NGS, NRAS mutation, EZH2 mutation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2730-6011

Access URL: https://doaj.org/article/4e62a3b7490d4351b57a54cd26908ddc

Response to trametinib, hydroxychloroquine, and bevacizumab in a young woman with NRAS-mutated metastatic intrahepatic cholangiocarcinoma: a case report

Authors: Aram A. Musaelyan, Ekaterina M. Anokhina, Alina I. Turdubaeva, Natalia V. Mitiushkina, Anastasia N. Ershova, Anna D. Shestakova, Aigul R. Venina, Evgeny N. Imyanitov, Sergey V. Orlov

Source: Exploration of Targeted Anti-tumor Therapy, Vol 5, Iss 3, Pp 780-788 (2024)

Subject Terms: intrahepatic cholangiocarcinoma, nras mutation, trametinib, hydroxychloroquine, bevacizumab, Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://www.explorationpub.com/Journals/etat/Article/1002246; https://doaj.org/toc/2692-3114

Access URL: https://doaj.org/article/15c6b988128b481890e948ca980a13a8

Preclinical evidence for employing MEK inhibition in NRAS mutated pediatric gastroenteropancreatic neuroendocrine-like tumors

Authors: Colin H. Quinn, Andee M. Beierle, Adele P. Williams, Raoud Marayati, Laura V. Bownes, Hooper R. Market, Michael E. Erwin, Jamie M. Aye, Jerry E. Stewart, Elizabeth Mroczek-Musulman, Karina J. Yoon, Elizabeth A. Beierle

Source: Translational Oncology, Vol 47, Iss , Pp 102045- (2024)

Subject Terms: Pediatric cancer, Target therapies, Patient-derived xenografts, Metastatic disease, NRAS mutation, MEK Inhibition, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523324001724; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/0515712cdd0f4633a52a9cf06e81c2dc

Advances in the treatment of advanced melanoma with NRAS gene mutation

Authors: ZHAO Bolun, ZHU Guannan

Source: Zhongguo aizheng zazhi, Vol 33, Iss 10, Pp 936-944 (2023)

Subject Terms: nras mutation, melanoma, carcinogenesis, targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.china-oncology.com/fileup/1007-3639/PDF/1698723448742-951764022.pdf; https://doaj.org/toc/1007-3639

Access URL: https://doaj.org/article/4fca9d0250b1423bbb0dcc7aa29329f5

First-in-human phase I dose-escalation and dose-expansion trial of the selective MEK inhibitor HL-085 in patients with advanced melanoma harboring NRAS mutations

Authors: Xuan Wang, Zhiguo Luo, Jing Chen, Yu Chen, Dongmei Ji, Li Fan, Ling Chen, Qian Zhao, Pei Hu, Peng Sun, Zhongwei Jia, Jun Guo, Lu Si

Source: BMC Medicine, Vol 21, Iss 1, Pp 1-12 (2023)

Subject Terms: HL-085, MEK inhibitor, Advanced melanoma, NRAS mutation, Circulating tumor DNA, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/c8dabd3a4e3f4c76bee2716e3f966d74

Case report: Therapeutic potential of T-VEC in combination with MEK inhibitors in melanoma patients with NRAS mutation

Authors: Sonja C. S. Simon, Verena Müller, Jochen S. Utikal

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: melanoma, T-VEC, MEK inhibitor, NRAS mutation, case series, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1111119/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/b1bd112b400144c08b8558480e671f81

Case report: Later onset of NRAS-mutant metastatic melanoma in a patient with a partially-excised giant congenital melanocytic nevus

Authors: Bruno Almeida Costa, Victor Zibara, Vasundhara Singh, Omid Hamid, Sonal Gandhi, Andrea P. Moy, Allison S. Betof Warner

Source: Frontiers in Medicine, Vol 9 (2022)

Subject Terms: metastatic melanoma, congenital melanocytic nevi, giant nevus, NRAS mutation, MDM2 amplification, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2022.1086473/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/f8c6fb8e829a498090d06bef6cf92499

Phase I pharmacokinetic study of an oral, small-molecule MEK inhibitor tunlametinib in patients with advanced NRAS mutant melanoma

Authors: Qian Zhao, Teng Wang, Huanhuan Wang, Cheng Cui, Wen Zhong, Diyi Fu, Wanlin Xi, Lu Si, Jun Guo, Ying Cheng, Hongqi Tian, Pei Hu

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: melanoma, NRAS mutation, mek inhibitor, pharmacokinetics, tunlametinib, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.1039416/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/7b0a553f3fe74737a5e3321c68b33b8c

The frequency and clinicopathological significance of NRAS mutations in primary cutaneous nodular melanoma in Indonesia

Authors: Hanggoro Tri Rinonce, Deflen Jumatul Sastri, Fita Trisnawati, Bidari Kameswari, Paranita Ferronika, Irianiwati

Source: Cancer Reports, Vol 5, Iss 1, Pp n/a-n/a (2022)

Subject Terms: Indonesia, nodular melanoma, NRAS mutation, RAS gene family, skin tumor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2573-8348

Access URL: https://doaj.org/article/be97aa1897014dd89da0fd688d13d8e7

An NRAS mutation in primary malignant melanoma of the lung: a case report

Authors: Takashi Hibiya, Meiro Tanaka, Mai Matsumura, Ayako Aoki, Tadashi Ikegami, Koji Okudela, Naomi Kawano, Kenichi Ohashi

Source: Diagnostic Pathology, Vol 15, Iss 1, Pp 1-6 (2020)

Subject Terms: Primary malignant melanoma of the lung, NRAS mutation, Sanger sequencing, Autopsy, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/1746-1596

Access URL: https://doaj.org/article/2a1de85d67b641b3a64799cc358ffbc5

Relevance and clinicopathologic relationship of BRAF V600E, TERT and NRAS mutations for papillary thyroid carcinoma patients in Northwest China

Authors: Meiling Huang, Changjiao Yan, Jingjing Xiao, Ting Wang, Rui Ling

Source: Diagnostic Pathology, Vol 14, Iss 1, Pp 1-10 (2019)

Subject Terms: BRAF V600E mutation, TERT mutation, NRAS mutation, Co-mutations, Papillary thyroid carcinoma, Pathology, RB1-214

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13000-019-0849-6; https://doaj.org/toc/1746-1596

Access URL: https://doaj.org/article/432dadfe6d87429b9e03ddd24fbb2669

Analysis of KRAS and NRAS mutations in Greek patients with metastatic Colorectal Cancer (mCRC) on the registry of the Gastro-intestinal Cancer Study Group (GIC-SG)

Authors: Gouvas Nikolaos, Kalambaliki Telenia, Voutsina Alexandra, Saridaki Zenia, Tzardi Maria, Kalykaki Aristea, Sfakianaki Maria, Athanasiadis Athanasios, Xynos Evaghelos, Boukovinas Ioannis, Souglakos John

Source: Forum of Clinical Oncology, Vol 9, Iss 1, Pp 31-36 (2019)

Subject Terms: kras-nras mutation, colorectal cancer, metastatic disease, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1792-362X

Access URL: https://doaj.org/article/bd9b256a7b0e4313a8fa70133728181b

In Model, In Vitro and In Vivo Killing Efficacy of Antitumor Peptide RDP22 on MUG-Mel2, a Patient Derived Cell Line of an Aggressive Melanoma Metastasis

Authors: Maximiliane Wußmann, Florian Kai Groeber-Becker, Sabrina Riedl, Dina Alihodzic, Daniel Padaric, Lisa Gerlitz, Alexander Stallinger, Bernadette Liegl-Atzwanger, Dagmar Zweytick, Beate Rinner

Source: Biomedicines, Vol 10, Iss 11, p 2961 (2022)

Subject Terms: melanoma metastases, NRAS mutation, antitumor peptide, tumor model systems, phosphatidylserine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/11/2961; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/2b6266e9095f4b44af0b6f234964aec9

Embryonic Expression of NrasG 12 D Leads to Embryonic Lethality and Cardiac Defects

Authors: Xiaona You, Myung-Jeom Ryu, Eunjin Cho, Yanzhi Sang, Alisa Damnernsawad, Yun Zhou, Yangang Liu, Jing Zhang, Youngsook Lee

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: Nras mutation, RASopathy, congenital heart defects, fetal liver hematopoiesis, embryonic development, Noonan syndrome, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.633661/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/61616fac3a9d456fa2f6b16adf00e978

Melanoma arising in a Giant congenital melanocytic nevus: two case reports

Authors: Tatiana S. Belysheva, Yana V. Vishnevskaya, Tatiana V. Nasedkina, Marina A. Emelyanova, Ivan S. Abramov, Kristina V. Orlova, Ludmila N. Lubchenko, Igor A. Utyashev, Marina B. Doroshenko, Lev V. Demidov, Mamed D. Aliev

Source: Diagnostic Pathology, Vol 14, Iss 1, Pp 1-9 (2019)

Subject Terms: Giant congenital melanocytic nevus, Melanoma, Neurocutaneous melanosis, Genetic analysis, NRAS mutation, Infants, Pathology, RB1-214

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13000-019-0797-1; https://doaj.org/toc/1746-1596

Access URL: https://doaj.org/article/ab9b7b4e1f8a40e1853614efbd30c4b6

Neurocutaneous Melanosis in Association With Large Congenital Melanocytic Nevi in Children: A Report of 2 Cases With Clinical, Radiological, and Pathogenetic Evaluation

Authors: Lei Chen, Liqin Zhai, Lika'a Fasih Y. Al-Kzayer, Shamil Naji Sarsam, Tingting Liu, Riyadh H. Alzakar, Yozo Nakazawa

Source: Frontiers in Neurology, Vol 10 (2019)

Subject Terms: congenital melanocytic nevi (CMN), neurocutaneous melanosis (NCM), CNS melanoma, leptomeningeal melanoma, NRAS mutation, large-CMN, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fneur.2019.00079/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/1d29bb1c65fb442485fbb5f8f9c5f023

Mutation Status and Immunohistochemical Correlation of KRAS, NRAS, and BRAF in 260 Chinese Colorectal and Gastric Cancers

Authors: Qiwei Yang, Sibo Huo, Yujie Sui, Zhenwu Du, Haiyue Zhao, Yu Liu, Wei Li, Xin Wan, Tongjun Liu, Guizhen Zhang

Source: Frontiers in Oncology, Vol 8 (2018)

Subject Terms: colorectal cancer, gastric cancer, KRAS mutation, NRAS mutation, BRAF mutation, immunohistochemistry, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2018.00487/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/484638785dc1433db4a7fa08ac4043f9

Superior efficacy and similar safety of double dose anakinra in Erdheim-Chester disease after single dose treatment

Authors: Fréderic Franconieri, Samuel Deshayes, Hubert de Boysson, Salim Trad, Nicolas Martin Silva, Benjamin Terrier, Boris Bienvenu, Françoise Galateau-Sallé, Jean-François Emile, Alison C. Johnson, Achille Aouba

Source: OncoImmunology, Vol 7, Iss 8 (2018)

Subject Terms: erdheim-chester disease, anakinra, braf mutation, nras mutation, vemurafenib, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/641d8ff2dc0049e886660ac5dced6cec

Prevalence of BRAF and NRAS mutations in cutaneous melanoma patients in Taiwan

Authors: Yi-Shuan Sheen, Yi-Hua Liao, Jau-Yu Liau, Ming-Hsien Lin, Yi-Chun Hsieh, Shiou-Hwa Jee, Chia-Yu Chu

Source: Journal of the Formosan Medical Association, Vol 115, Iss 2, Pp 121-127 (2016)

Subject Terms: BRAF mutation, melanoma, NRAS mutation, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S092966461500073X; https://doaj.org/toc/0929-6646

Access URL: https://doaj.org/article/e68ad552612643fd9c02e2296ff68833

Management of Two Juvenile Myelomonocytic Leukemia Patients According to Clinical and Genetic Features

Authors: Özlem Tüfekçi, Hale Ören, Fatma Demir Yenigürbüz, Salih Gözmen, Tuba Hilkay Karapınar, Gülersu İrken

Source: Turkish Journal of Hematology, Vol 32, Iss 2, Pp 175-179 (2015)

Subject Terms: c-cbl mutation, childhood, juvenile myelomonocytic leukemia, nras mutation, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-99710; https://doaj.org/toc/1308-5263

Access URL: https://doaj.org/article/a34836102efe426db17c92b14a94fb6b