Efficacy and Safety of Nicorandil in the Treatment of Stable Angina Pectoris.

Authors: Xuan Wang¹, Haojing Chen¹ Chenhaojing2000@126.com

Source: Alternative Therapies in Health & Medicine. May2024, Vol. 30 Issue 5, p130-135. 6p.

Subject Terms: *NICORANDIL, *DRUG efficacy, *CORONARY disease, *ANGINA pectoris, *PHYSICAL activity, *CORONARY circulation, *CHEST pain

Linking KATP channel activation to p-AKT/mTORC1/eEF2/BDNF axis unravels Nicorandil's promise in countering acetaminophen-induced hepatic encephalopathy in mice

Authors: Essam, Reham M. ^{a, b}, Mohamed, Yasmin S. ^a, El-Sayed, Sarah S. ^a, Kamel, Nada M. ^{a, ⁎}

Source: In Life Sciences 1 April 2025 366-367

Effects of Fisetin and Nicorandil on adjuvant-induced rheumatoid arthritis in rats: Emerging role of TLR4/NF-κB-induced Pyroptosis, Nrf-2/HO-1, and OPG/RANKL pathways

Authors: Okasha, Asmaa H. ^{a, ⁎}, Hegab, Islam Ibrahim ^{b, c}, Seleem, Monira A. ^d, Azzam, Asmaa R. ^e, Ibrahim, Sarah ^e, Ghalwash, Asmaa A. ^a, El-Gohary, Rehab M. ^a

Source: In Cytokine March 2025 187

Nicorandil Ameliorates Depression‐Like Behaviors After Traumatic Brain Injury by Suppressing Ferroptosis Through the SLC7A11/GPX4 Axis in the Hippocampus

Authors: Yao‐Ran Tu, Ming Tan, Yao Li, De‐Quan Hong, Fan Niu

Source: Brain and Behavior, Vol 15, Iss 1, Pp n/a-n/a (2025)

Subject Terms: depression, ferroptosis, nicorandil, the SLC7A11/GPX4 axis, traumatic brain injury, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3279

Access URL: https://doaj.org/article/64441ded7ea141a5952e510a9bb619cf

Effect of remote ischemic preconditioning, nicorandil, and trimetazidine in contrast-induced nephropathy: a network meta-analysis of randomized controlled trials

Authors: Hanchao Gao, Weilong Li, Chuanchuan Sun, Shiping Zhu, Fanna Liu, Xinhai Zhao, Shaodong Luan, Shengyun Sun, Yeye Yu

Source: Renal Failure, Vol 46, Iss 2 (2024)

Subject Terms: Contrast-induced nephropathy, remote ischemic preconditioning, nicorandil, trimetazidine, network meta-analysis, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/0886-022X; https://doaj.org/toc/1525-6049

Access URL: https://doaj.org/article/e2be7ec3632b439a9a95ed952573307b

Spontaneous Mucocutaneous Ulcerations: A Quiz

Authors: Jakob L. Drivenes, Anette Bygum

Source: Acta Dermato-Venereologica, Vol 104 (2024)

Subject Terms: Skin ulcerations, nicorandil, vulvar ulceration, drug-induced ulcers, Nicorandil-induced ulcerations, wound care, Dermatology, RL1-803

File Description: electronic resource

Relation: https://medicaljournalssweden.se/actadv/article/view/41006; https://doaj.org/toc/0001-5555; https://doaj.org/toc/1651-2057

Access URL: https://doaj.org/article/7de1185aa1a643f99b2244b238b3e1e8

Nicorandil alleviated cardiac hypoxia/reoxygenation-induced cytotoxicity via upregulating ketone body metabolism and ACAT1 activity.

Authors: Yan Ping Bai¹, Lei Sen Han² hanleisen196601@126.com

Source: Korean Journal of Physiology & Pharmacology. Jan2019, Vol. 23 Issue 1, p37-45. 9p.

Subject Terms: *NICORANDIL, *HYPOXEMIA, *CELL-mediated cytotoxicity, *KETONES, *ACETYL-CoA acyltransferase, *APOPTOSIS

Protective effects of nicorandil against cerebral injury in a swine cardiac arrest model.

Authors: Zhu, Fangfang¹, Zhong, Xia¹, Zhou, Yi¹, Hou, Zhiqiang¹, Hu, Haoran¹, Liang, Lining¹, Chen, Jibin¹, Chen, Qianqian¹, Ji, Xianfei¹ sdslyysdy123@163.com, Shang, Deya¹ sdslyysdy123@163.com

Source: Experimental & Therapeutic Medicine. Jul2018, Vol. 16 Issue 1, p37-44. 8p.

Subject Terms: *NICORANDIL, *CEREBELLUM injuries, *CARDIAC arrest, *CARDIOPULMONARY resuscitation, *VENTRICULAR fibrillation

Nicorandil restores endothelial cell Kir6.2 expression to alleviate neuropathic pain in mice after chronic constriction injury

Authors: Du, Minghao ^{a, 1}, Li, Jiani ^{b, 1}, Ren, Xiaoyu ^c, Zhao, Jian ^c, Miao, Yu ^{a, ⁎}, Lu, Yichen ^{c, ⁎}

Source: In International Immunopharmacology 25 December 2024 143 Part 2

Effects of intracoronary administration of small doses of nicorandil and verapamil on blood pressure and heart rate

Authors: Sha Liu, Yuangang Qiu, Chuqun Lv

Source: American Heart Journal Plus, Vol 46, Iss , Pp 100461- (2024)

Subject Terms: Nicorandil, Verapamil, Intracoronary, Blood pressure, Heart rate, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666602224001046; https://doaj.org/toc/2666-6022

Access URL: https://doaj.org/article/b99c39ac91c84c108f6bae35b16c8d5e

Nicorandil mitigates arthrogenic contracture induced by knee joint extension immobilization in rats: interference with RhoA/ROCK signaling and TGF-β1/Smad pathway

Authors: XM Li, K Wang, M Liu, QB Zhang, Y Zhou

Source: European Cells & Materials, Vol 47, Pp 59-72 (2024)

Subject Terms: nicorandil, arthrogenic contracture, fibrosis, tgf-β1/smad signaling pathway, rhoa/rock signaling pathway, Diseases of the musculoskeletal system, RC925-935, Orthopedic surgery, RD701-811

File Description: electronic resource

Relation: https://www.ecmjournal.org/papers/vol047/vol047a05.php; https://doaj.org/toc/1473-2262

Access URL: https://doaj.org/article/4cf2bd4d047845e39efd380cb65a2ead

Nicorandil-Pretreated Mesenchymal Stem Cell-Derived Exosomes Facilitate Cardiac Repair After Myocardial Infarction via Promoting Macrophage M2 Polarization by Targeting miR-125a-5p/TRAF6/IRF5 Signaling Pathway

Authors: Gong ZT, Xiong YY, Ning Y, Tang RJ, Xu JY, Jiang WY, Li XS, Zhang LL, Chen C, Pan Q, Hu MJ, Xu J, Yang YJ

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 2005-2024 (2024)

Subject Terms: mesenchymal stem cell, exosomes, nicorandil, macrophage polarization, myocardial infarction, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/nicorandil-pretreated-mesenchymal-stem-cell-derived-exosomes-facilitat-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/910100e9934a4b31947ba495b51c1e3b

Protective effect of nicorandil on myocardial injury following percutaneous coronary intervention in older patients with stable coronary artery disease: Secondary analysis of a randomized, controlled trial (RINC).

Authors: Kawakita, Norifumi¹, Ejiri, Kentaro¹, Miyoshi, Toru¹ miyoshit@cc.okayama-u.ac.jp, Kohno, Kunihisa¹, Nakahama, Makoto², Doi, Masayuki³, Munemasa, Mitsuru⁴, Murakami, Masaaki⁵, Nakamura, Kazufumi¹, Ito, Hiroshi¹, null, null

Source: PLoS ONE. 4/16/2018, Vol. 13 Issue 4, p1-14. 14p.

Subject Terms: *NICORANDIL, *MYOCARDIAL infarction treatment, *PERCUTANEOUS coronary intervention, *OLDER patients, *RANDOMIZED controlled trials, *DISEASES, *THERAPEUTICS

Nicorandil for the prevention of contrast‐induced nephropathy: A meta‐analysis of randomized controlled trials.

Authors: Ma, Xiaofen¹, Li, Xiang¹, Jiao, Zhanfeng¹, Zhang, Yiming¹ zhangym17@sina.com

Source: Cardiovascular Therapeutics. Apr2018, Vol. 36 Issue 2, p1-1. 9p.

Subject Terms: *KIDNEY disease prevention, *NICORANDIL, *DISEASE incidence, *RANDOMIZED controlled trials, *META-analysis, *THERAPEUTICS, *CONTRAST induced nephropathy

Correction of morphofunctional disturbances arising when modelling Preeclampsia with resveratrol and nicorandil.

Authors: Stupakova, Elena G.¹ miss.stupackova@yandex.ru, Lazareva, Galina A.¹ akush.fpo@gmail.com, Gureev, Vladimir V.x¹ gureev@bsu.edu.ru

Source: Research Results in Pharmacology. 2018, Vol. 4 Issue 1, p59-71. 13p.

Subject Terms: *NICORANDIL, *PREECLAMPSIA, *MATERNAL mortality, *PROTEINURIA, *BLOOD pressure

Formulation and Evaluation of Microsponge Based Nicorandil Sustained Released Tablet.

Authors: Patel, S. S.¹ onlysanju2004@yahoo.co.in, Patel, M. R.¹, Patel, M. J.¹

Source: Journal of Scientific Research. 2017, Vol. 9 Issue 3, p285-296. 12p.

Subject Terms: *CARDIOVASCULAR disease treatment, *NICORANDIL, *POTASSIUM channels, *THERAPEUTICS

Effects of Tongluo Huoxue Recipe Combined with Nicorandil on Cardiac Function of Stable Angina Pectoris

Authors: Zhao, Zhilei, Li, Ruiyu

Source: 2018 9th International Conference on Information Technology in Medicine and Education (ITME) ITME Information Technology in Medicine and Education (ITME), 2018 9th International Conference on. :785-788 Oct, 2018

Relation: 2018 9th International Conference on Information Technology in Medicine and Education (ITME)

Effect of Perioperative Nicorandil on Myocardial Protection in Patients Undergoing Cardiac Surgery with Cardiopulmonary Bypass, a Retrospective Study

Authors: Chen Y, Liu Y, Lv H, Li Q, Shen J, Chen W, Shi J, Zhou C

Source: Drug Design, Development and Therapy, Vol Volume 18, Pp 223-231 (2024)

Subject Terms: nicorandil, cardiopulmonary bypass, perioperative myocardial injury, acute kidney injury, acute liver injury, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/effect-of-perioperative-nicorandil-on-myocardial-protection-in-patient-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

Access URL: https://doaj.org/article/8445d94e53c54777a853e30e9ebe68b3

Metabolic model for laboratory control of anti-ischaemic therapy effectiveness: a case study of nicorandil

Authors: T. F. Subbotina, Yu. A. Kudaev, N. L. Lokhovinina, M. Z. Alugishvili, I. T. Abesadze, I. V. Titenkov, M. A. Chernyavskiy, A. V. Panov, A. A. Zhloba

Source: Регуляторные исследования и экспертиза лекарственных средств, Vol 13, Iss 4, Pp 540-548 (2023)

Subject Terms: nicorandil, coronary heart disease, arginine, citrulline, homoarginine, asymmetrical dimethylarginine, nitric oxide synthase, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.vedomostincesmp.ru/jour/article/view/535; https://doaj.org/toc/3034-3062; https://doaj.org/toc/3034-3453

Access URL: https://doaj.org/article/24e0d3e6c68d47f49da23db31352c51c

Perioperative myocardial injury in patients with coronary artery disease during elective lower limb surgery

Authors: Yu. A. Kudaev, A. V. Vorobeva, N. L. Lokhovinina, I. T. Abesadze, M. Z. Alugishvili, I. V. Titenkov, M. A. Chernyavsky, A. V. Panov

Source: Рациональная фармакотерапия в кардиологии, Vol 19, Iss 5, Pp 444-451 (2023)

Subject Terms: nicorandil, coronary artery disease, perioperative myocardial injury, lower extremity revascularization, Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.rpcardio.online/jour/article/view/2937; https://doaj.org/toc/1819-6446; https://doaj.org/toc/2225-3653

Access URL: https://doaj.org/article/8d027ec1cfcf4f4aabb50987f7578623