Dual-phase SilMA hydrogel: a dynamic scaffold for sequential drug release and enhanced spinal cord repair via neural differentiation and immunomodulation

Authors: Ruizhi Zhang, Mingzhe Zhang, Lu Chen, Linlin Jiang, Chenbo Zou, Na Li, Hengxing Zhou, Shiqing Feng

Source: Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)

Subject Terms: spinal cord injury, SilMA hydrogel, neurotrophin-3, angiotensin-(1–7), immunomodulation, neural differentiation, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2024.1501488/full; https://doaj.org/toc/2296-4185

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A large hypothesis-free proteomics study investigating serum inflammatory markers as biomarkers of dry eye disease

Authors: Vehof, Jelle ^{a, b, c, d, ⁎, 1}, Rhee, Amber ^{a, e, 1}, Rossi, Niccolò ^a, Falchi, Mario ^a, Hammond, Christopher J. ^{a, f, 1}, Williams, Frances M.K. ^{a, 1}

Source: In The Ocular Surface April 2025 36:198-208

Transplantation of peripheral nerve tissueoid based on a decellularized optic nerve scaffold to restore rat hindlimb sensory and movement functions

Authors: Zhu, Zhao-Wei ^{a, 1}, Li, Ge ^{b, 1}, Wu, Guang-Geng ^{a, 1}, Zhang, Yu-Jing ^{c, 1}, Bai, Yu-Rong ^d, Lai, Bi-Qin ^{d, e}, Ding, Ying ^d, Zeng, Xiang ^d, Ma, Yuan-Huan ^d, Liu, Shu ^g, Wang, Rui ^b, Liang, Jing-Hua ^b, Xu, Yang-Bin ^{a, ⁎⁎⁎}, He, Bo ^{f, ⁎⁎}, Zeng, Yuan-Shan ^{d, e, ⁎}

Source: In Biomaterials April 2025 315

Construction of functional neural network tissue combining CBD-NT3-modified linear-ordered collagen scaffold and TrkC-modified iPSC-derived neural stem cells for spinal cord injury repair

Authors: Zhaoping Wu, Yi Zhou, Xianglin Hou, Weidong Liu, Wen Yin, Lei Wang, Yudong Cao, Zhipeng Jiang, Youwei Guo, Quan Chen, Wen Xie, Ziqiang Wang, Ning Shi, Yujun Liu, Xiang Gao, Longlong Luo, Jianwu Dai, Caiping Ren, Xingjun Jiang

Source: Bioactive Materials, Vol 35, Iss , Pp 242-258 (2024)

Subject Terms: Spinal cord injury, Induced pluripotent stem cells, LOCS, Neural network tissue, Neurotrophin-3, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24000227; https://doaj.org/toc/2452-199X

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Neurotrophin-3 promotes peripheral nerve regeneration by maintaining a repair state of Schwann cells after chronic denervation via the TrkC/ERK/c-Jun pathway

Authors: Xiong Xu, Lili Song, Yueying Li, Jin Guo, Shuo Huang, Shuang Du, Weizhen Li, Rangjuan Cao, Shusen Cui

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-20 (2023)

Subject Terms: Neurotrophin-3, c-Jun, Chronic denervation, Peripheral nerve regeneration, Repair Schwann cell, ERK pathway, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/7ad37d11183543dc8bb57f24884a97f1

Effects of Whole-Body Vibration and Manually Assisted Locomotor Therapy on Neurotrophin-3 Expression and Microglia/Macrophage Mobilization Following Thoracic Spinal Cord Injury in Rats

Authors: Diana Schaufler, Maria Eleni Manthou, Paschalis Theotokis, Svenja Rink-Notzon, Doychin N. Angelov

Source: Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3238-3254 (2023)

Subject Terms: microglia, Iba1, neurotrophin-3, spinal cord injury, vibration therapy, functional recovery, Biology (General), QH301-705.5

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Relation: https://www.mdpi.com/1467-3045/45/4/211; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/8c052f51af6e4678b4b995fe6a215592

Neuroprotective effects of Neurotrophin-3 in MPTP-induced zebrafish Parkinson’s disease model

Authors: Noor Azzizah Omar, Jaya Kumar, Seong Lin Teoh

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: neurodegenerative disease, neurotrophin-3, danio rerio, neuronal survival, neurotoxin, dopaminergic neuron, Therapeutics. Pharmacology, RM1-950

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Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1307447/full; https://doaj.org/toc/1663-9812

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Interleukin-6 as a Director of Immunological Events and Tissue Regenerative Capacity in Hemodialyzed Diabetes Patients

Authors: Maria-Florina Trandafir, Octavian Savu, Daniela Pasarica, Coralia Bleotu, Mihaela Gheorghiu

Source: Medical Sciences, Vol 12, Iss 2, p 31 (2024)

Subject Terms: interleukin 6, interleukin-soluble receptor, neurotrophin-3, vascular endothelial growth factor β, hemodialysis, diabetes mellitus, Medicine

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Relation: https://www.mdpi.com/2076-3271/12/2/31; https://doaj.org/toc/2076-3271

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A comparative study on the secretion of various cytokines by pulp stem cells at different passages and their neurogenic potential

Authors: Ming Yan, Ola A. Nada, Ling-Ling Fu, Dong-Zhen Li, Hong-Chao Feng, Li-Ming Chen, Martin Gosau, Reinhard E. Friedrich, Ralf Smeets

Source: Biomedical Papers, Vol 166, Iss 2, Pp 161-167 (2022)

Subject Terms: dental pulp stem cell, vascular endothelial growth factor, brain-derived neurotrophic factor, nerve growth factor, neurotrophin-3. immunophenotype, multidirectional differentiation, cytokines, Medicine

File Description: electronic resource

Relation: https://biomed.papers.upol.cz/artkey/bio-202202-0006_a-comparative-study-on-the-secretion-of-various-cytokines-by-pulp-stem-cells-at-different-passages-and-their-ne.php; https://doaj.org/toc/1213-8118; https://doaj.org/toc/1804-7521

Access URL: https://doaj.org/article/36b0ca91a51743408bb6c50fb0c37b9f

An NT-3-releasing bioscaffold supports the formation of TrkC-modified neural stem cell-derived neural network tissue with efficacy in repairing spinal cord injury

Authors: Ge Li, Bao Zhang, Jia-hui Sun, Li-yang Shi, Meng-yao Huang, Li-jun Huang, Zi-jing Lin, Qiong-yu Lin, Bi-qin Lai, Yuan-huan Ma, Bin Jiang, Ying Ding, Hong-bo Zhang, Miao-xin Li, Ping Zhu, Ya-qiong Wang, Xiang Zeng, Yuan-shan Zeng

Source: Bioactive Materials, Vol 6, Iss 11, Pp 3766-3781 (2021)

Subject Terms: Neurotrophin-3, Tropomyosin kinase receptor C, Self-organization, Neural network tissue, Spinal cord injury, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S2452199X2100147X; https://doaj.org/toc/2452-199X

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Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration

Authors: Zheng Yang, Yang Yang, Yichi Xu, Weiqian Jiang, Yan Shao, Jiahua Xing, Youbai Chen, Yan Han

Source: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Peripheral nerve, Regeneration, Exosomes, Neurotrophin-3, Nerve guidance conduit, Medicine (General), R5-920, Biochemistry, QD415-436

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Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/481f25936fee4137aaa19df95246d67e

Neurotrophin‐3 contributes to benefits of human embryonic stem cell‐derived cardiovascular progenitor cells against reperfused myocardial infarction

Authors: Wei Bi, Jinxi Wang, Yun Jiang, Qiang Li, Shihui Wang, Meilan Liu, Qiao Liu, Fang Li, Christian Paul, Yigang Wang, Huang‐Tian Yang

Source: Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 756-772 (2021)

Subject Terms: apoptosis, cardiac repair, ERK‐Bim signaling pathway, human embryonic stem cell‐derived cardiovascular progenitor cells, neurotrophin‐3, Medicine (General), R5-920, Cytology, QH573-671

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Relation: https://doaj.org/toc/2157-6564; https://doaj.org/toc/2157-6580

Access URL: https://doaj.org/article/3f4e74cf59b04524a656165bfa0f2e27

Dental pulp stem cells stimulate neuronal differentiation of PC12 cells

Authors: Nessma Sultan, Laila E Amin, Ahmed R Zaher, Mohammed E Grawish, Ben A Scheven

Source: Neural Regeneration Research, Vol 16, Iss 9, Pp 1821-1828 (2021)

Subject Terms: brain-derived neurotrophic factor, conditioned medium, dental pulp stem cell, glial cell line-derived nerve growth factor, neurite outgrowth, neurotrophic factor, neurotrophin-3, phaeochromocytoma pc12 cell, Neurology. Diseases of the nervous system, RC346-429

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Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=9;spage=1821;epage=1828;aulast=Sultan; https://doaj.org/toc/1673-5374

Access URL: https://doaj.org/article/e8c8f8dda71e4d6fa8524c0d2b4270fc

Decellularized optic nerve functional scaffold transplant facilitates directional axon regeneration and remyelination in the injured white matter of the rat spinal cord

Authors: Yu-Rong Bai, Bi-Qin Lai, Wei-Tao Han, Jia-Hui Sun, Ge Li, Ying Ding, Xiang Zeng, Yuan-Huan Ma, Yuan-Shan Zeng

Source: Neural Regeneration Research, Vol 16, Iss 11, Pp 2276-2283 (2021)

Subject Terms: axonal regeneration, decellularized optic nerve, directional regeneration, functional scaffold, microenvironment, neurotrophin-3, optic nerve, remyelination, schwann cells, tissue engineering, white matter injury, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=11;spage=2276;epage=2283;aulast=Bai; https://doaj.org/toc/1673-5374

Access URL: https://doaj.org/article/e30a57bb396e4215ab07d341b7926233

Neurotrophin-3 accelerates reendothelialization through inducing EPC mobilization and homing

Authors: Chen Yan, Cao Jian, Peng Weixia, Chen Wen

Source: Open Life Sciences, Vol 15, Iss 1, Pp 241-250 (2020)

Subject Terms: neurotrophin-3, endothelialization, endothelial progenitor cells, intravascular stent, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2391-5412

Access URL: https://doaj.org/article/4e8f93dd2c0646c59f1ab2ef7935d559

Inhibition of Adult Hippocampal Neurogenesis Plays a Role in Sevoflurane-Induced Cognitive Impairment in Aged Mice Through Brain-Derived Neurotrophic Factor/Tyrosine Receptor Kinase B and Neurotrophin-3/Tropomyosin Receptor Kinase C Pathways

Authors: Lichi Xu, Yanjing Guo, Gongming Wang, Guoqing Sun, Wei Sun, Jingjing Li, Xinlei Li, Jiangnan Wu, Mengyuan Zhang

Source: Frontiers in Aging Neuroscience, Vol 14 (2022)

Subject Terms: aging, sevoflurane, cognitive impairment, brain-derived neurotrophic factor, neurotrophin-3, adult hippocampal neurogenesis (AHN), Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2022.782932/full; https://doaj.org/toc/1663-4365

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Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

Authors: Michele Fornaro, Alessia Giovannelli, Angelica Foggetti, Luisa Muratori, Stefano Geuna, Giorgia Novajra, Isabelle Perroteau

Source: Neural Regeneration Research, Vol 15, Iss 9, Pp 1732-1739 (2020)

Subject Terms: brain-derived neurotrophic factor, directionality, dorsal root ganglia explant, nerve growth factor, nerve regeneration, neurite growth enhancement, neurotrophic factors, neurotrophin-3, sensory neurons, tortuosity chinese library classification no. r453, r364, r741, Neurology. Diseases of the nervous system, RC346-429

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Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=9;spage=1732;epage=1739;aulast=Fornaro; https://doaj.org/toc/1673-5374

Access URL: https://doaj.org/article/f6b8485010e44665a7e5f0fbc32bfb2f

Histological and functional outcomes in a rat model of hemisected spinal cord with sustained VEGF/NT-3 release from tissue-engineered grafts

Authors: Zi-Xing Xu, Li-Qun Zhang, Yi-Nan Zhou, Xue-Min Chen, Wei-Hong Xu

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 48, Iss 1, Pp 362-376 (2020)

Subject Terms: Spinal cord injury (SCI), vascular endothelial growth factor (VEGF), neurotrophin-3 (NT-3), poly (lactic-co-glycolic acid) (PLGA) nanoparticles, angiogenesis, neural repair, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

Access URL: https://doaj.org/article/565285d5dd654bd4ab3c0f4e21e36461

A Novel Small Molecule Neurotrophin-3 Analogue Promotes Inner Ear Neurite Outgrowth and Synaptogenesis In vitro

Authors: Judith S. Kempfle, Marlon V. Duro, Andrea Zhang, Carolina D. Amador, Richard Kuang, Ryan Lu, Boris A. Kashemirov, Albert S. Edge, Charles E. McKenna, David H. Jung

Source: Frontiers in Cellular Neuroscience, Vol 15 (2021)

Subject Terms: inner ear, regeneration, synaptopathy, neurotrophin-3, bisphosphonate, small molecule, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

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Relation: https://www.frontiersin.org/articles/10.3389/fncel.2021.666706/full; https://doaj.org/toc/1662-5102

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NT3/TrkC Pathway Modulates the Expression of UCP-1 and Adipocyte Size in Human and Rodent Adipose Tissue

Authors: María Bové, Fermi Monto, Paloma Guillem-Llobat, M Dolores Ivorra, M Antonia Noguera, Andrea Zambrano, M Salome Sirerol-Piquer, Ana Cristina Requena, Mauricio García-Alonso, Teresa Tejerina, José T. Real, Isabel Fariñas, Pilar D’Ocon

Source: Frontiers in Endocrinology, Vol 12 (2021)

Subject Terms: neurotrophin-3, tropomyosin-related kinase receptor C, beta-adrenoceptors, white adipose tissue, brown adipose tissue, adipocytes, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

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Relation: https://www.frontiersin.org/articles/10.3389/fendo.2021.630097/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/a48f19f2d4c1487abe3bf6fef9510af9