Distribution and neurochemical characterisation of neurons containing neuregulin 1 in the enteric nervous system within the porcine small intestine

Authors: Puchała Łukasz, Gonkowski Sławomir, Rytel Liliana, Wojtkiewicz Joanna, Grzegorzewski Waldemar Jarosław

Source: Journal of Veterinary Research, Vol 68, Iss 4, Pp 623-632 (2024)

Subject Terms: neuregulin 1, enteric neurons, domestic pig, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/2450-8608

Access URL: https://doaj.org/article/5acfd577d9ca425b9455228031df364a

The Potential of Neuregulin 4 as a Novel Biomarker and Therapeutic Agent for Vascular Complications in Type 2 Diabetes Mellitus

Authors: Dan X, Li K, Xu J, Yan P

Source: Journal of Inflammation Research, Vol Volume 17, Pp 8543-8554 (2024)

Subject Terms: neuregulin 4, adipokine, diabetes, type 2, vascular complications, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/the-potential-of-neuregulin-4-as-a-novel-biomarker-and-therapeutic-age-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Access URL: https://doaj.org/article/753ed04bf527417e9b2a4934c1e6eef3

Feature Papers in Bioactives and Nutraceuticals

Contributors: Battino, Maurizio

Subject Terms: whey proteins, metal–protein interactions, food storage, food safety, nutraceuticals, metallocomplexes, biologically active compounds, saccharides, cyclitols, electrochemistry, MALDI-TOF-MS, morusin, antioxidants, natural products, cell signaling, inflammatory diseases, neurological disorders, diabetes, cancer, jasmonic acid, jasmone derivatives, phytopathogenic fungi, crop protection, thiosemicarbazones, mycotoxins, mycopesticides, NAD, redox cofactor, nicotinamide, pyridones, atopic dermatitis, chrysin, 2,4-dinitrochlorobenzene, early growth response 1, thymic stromal lymphopoietin, Cassia abbreviata, HIV-1 entry, piceatannol, structure-activity relationship, pharmacophoric studies, norartocarpetin, coronavirus disease 2019, severe acute respiratory syndrome coronavirus 2, vitamin D, adaptive immunity, innate immunity, angiotensin-converting enzyme 2, renin–angiotensin–aldosterone system, resveratrol, phenylacetamide RSV derivatives, breast cancer cell lines, antiproliferative activity, anti-inflammatory activity, cell cycle arrest, cell death, prenylated flavonoids, synthesis, antibacterial, MRSA, synergism, antifungal, carnosic acid, ROS generation, ROS neutralization, Nox4 enzyme translation, NF-?B translocation, IkB? phosphorylation, HO-1 translation, Nrf2 translocation, hydroxyphenyl-pyranoanthocyanins, naturally derived pigments, accelerated formation, 10-catechyl-pyranoanthocyanins, liver cirrhosis, portal hypertension, angiogenesis, portosystemic collateral shunting, glycyrrhizin, 5-LOX, polyphenols, inflammation, leukotrienes, eicosanoids, hemiketals, arachidonic acid, oleanolic acid, keratinocyte, NF-?B, STAT1, milk, extracellular vesicles, mEVs, RNAseq, miRNA, anti-inflammatory, immunomodulatory, cow, donkey, goat, Alzheimer’s disease, ascorbic acid, Caenorhabditis elegans, collagen, dityrosine crosslinking, oxidative stress, vitamin B12 deficiency, functional nutrition, emerging contaminants, urolithins, chemoprevention, neuroprotection, DNA damage, estrogenicity, microbiome, bioactives, dithiocarbamate, metal complexes, medical use, industrial applications, agricultural applications, bioactive peptide, anti-aging, rodents, hematopoietic stem cell, nutrient, catabolism, anabolism, dietary intervention, obesity, lipase inhibitors, theophylline, Fu Brick tea, preadipocytes, spermatozoa, infertility, fatty acids, sugar, bioactive molecules, mitochondria, metabolism, sepsis, pathophysiology, gaseous mediators, NO, CO, H2S, therapeutic targets, disease, nano-carrier, starch, linear dextrin, cyclic dextrin, nanosponges, drug delivery, nutraceutical delivery, neferine, anti-seizure, antiinflammation, NLRP3 inflammasome, kainic acid, hippocampus, folate, purine biosynthesis, methionine, S-adenosylmethionine, S-adenosylhomocysteine, homocysteine, cysteine, glutathione, choline, methionine sulfoxide, liver fibrosis, antioxidant, electroretinography, visual evoked potential, neuregulin 1, schizophrenia, urolithin A, poly(I:C), TLR3, MAPK, human pluripotent stem cells, hESCs, minilungs, vitamin D analogs, paricalcitol, calcipotriol, lung fibrosis, aryl sulfotransferase, Desulfitobacterium hafniense, HPLC analysis, sulfates, flavonoids, phenolic acid, carnosine, glioblastoma, fibroblasts, imidazole-containing compounds, cell viability, high-performance liquid chromatography coupled to mass spectrometry, flavonoid, chalcone-based compounds, NLRP3-inflammasome inhibitors, anti-parasitic, Clerodendrum spp., cytotoxic, diterpenoids, insecticidal, curcumin, nanoparticles, diclofenac sodium, carrageenan, cytokines, protein inhibitors, Liriomyza trifolii, molecular docking, inhibitory activity, protein-ligand interactions, yeast extraction, bean-leaf extraction, DPP-IV inhibitor, hypoglycemic peptides, type 2 diabetes mellitus, enzymatic hydrolysis, dietary polyphenols, high performance liquid chromatography, functional food, in vitro two-stage simulated gastrointestinal digestion, wild garlic, antioxidant activity, extrusion-cooking, processing parameters, flavonolignans, halogenation, biological activity, multidrug resistance, bacteria, intestinal permeability, gut barrier, leaky gut, ivermectin, hepatic stellate cells, TGF-?1, cannabis, selenium, necrotic enteritis, muscle abnormalities, intestinal epithelial cells, hypoxia, heat stress, epithelial integrity, nutritional components, tight junction, cigarette smoke, plant sterols, eryptosis, DISC, caspases, p38 MAPK, St. John’s wort, cell cycle regulation, apoptosis, ferroptosis, autophagy, STAT3, HIF1?, CREB, selenoproteins, selenium deficiency, human diseases, epigenetics, phytoremediation, rhizofiltration, contact dermatitis, cystathionine ?-lyase, cytokine, hydrogen sulfide, inflammatory bowel disease, mercaptopyruvate sulfurtransferase, systemic immunity, Th1/Th2 balance, trinitrochlorobenzene, ulcerative colitis, Cornelian cherry, iridoids, anthocyanins, atherosclerosis, atherogenesis, oxidation, adhesion, natural product, stereochemistry, NMR shift parameter development, DFT calculations, ECD calculations, antimigratory effect, yeast surface display, Pichia pastoris, biofilm, galactooligosaccharides, galactosidase, fish oil replacement, Seriola dumerili, greater amberjack, antioxidant enzymes, blood parameters, fish health, Verbena officinalis, natural killer cells, killing efficiency, C3G, anthocyanin, IBD, Crohn’s disease, selenoenzyme, selenocysteine, catalytic mechanism, glutathione peroxidase, thioredoxin reductase, deiodinase, methionyl-sulfoxide reductase, glycine reductase, D-proline reductase, formate dehydrogenase, hydrogenase, redox regulation, equol, menopause, bone metabolism markers, bone mineral density, phenolic compounds, mass spectrometry, colon cancer, anti-proliferative activity, gut microbiota, juvenile hormone, juvenile hormone binding protein, silk protein, Bombyx mori, cystathionine gamma-lyase, adhesion molecules, endothelial cells, perfluoroalkyl substances, fermented red beetroot juice, human body fluids, wholegrains, cooking, digestion, fermentation, bioaccessibility, next-generation sequencing, UPLC-MS/MS, bioavailability, cannabidiol, CBD, solubility, stability, quercetin, acylation, metabolites, sinapic acid, serum albumin, thermal stability, denaturation, aggregation, bioactive compounds, Prunus domestica L. seed, cascade valorization, oils, brandy processing, oxidative stability, antimicrobial activity, anti-amyloidogenic activity, nutraceutical application, SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, SIRT7, Citrus fruits, ultrasound-assisted extraction, vulvovaginal candidiasis, dandelion root, burdock root, raw material, bioactive substances, vitamins, Escherichia coli, natural extracts, neuropathy, nutraceutical approach, nerve injury, intestinal absorption, synergy effect, perishable fruits, ethanolic extracts, chemical and biological changes, polyphenols dynamic, minerals partition, cytotoxicity and anti-proliferative, human tumor colon cell line Caco-2, Mathematics and Science, Biology, life sciences

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Access URL: https://directory.doabooks.org/handle/20.500.12854/139318
https://mdpi.com/books/pdfview/book/9315

Neuregulin 1 improved gastric motility and reduced gastric inflammation by activating the α7nAChR through the cholinergic anti-inflammatory pathway in diabetic rats

Authors: Cui, Weigang ^{a, b, c, ⁎}, Ma, Yuqi ^{b, d}, Zhang, Libin ^e, Zhang, Lei ^c, Yao, Qianyin ^a, Zhang, Jie ^a, Cheng, Yatao ^a, Zeng, Wenqin ^a, Liu, Qin ^a, Liu, Fengyun ^a, Liang, Chunyan ^f

Source: In Toxicology and Applied Pharmacology February 2025 495

Disrupted neuregulin 1-ErbB4 signaling: Consequences of prenatal morphine exposure in rat pups and molecular gateway to neurological impairment

Authors: Samira Khayat, Hamed Fanaei, Hamid Hafezinouri, Abdolhakim Ghanbarzehi, Abolfazl Parsi-Moud, Ilia Mirzaei

Source: Toxicology Reports, Vol 13, Iss , Pp 101687- (2024)

Subject Terms: Morphine, Neuregulin 1, ErbB4, Pregnancy, Inflammation, Neurodevelopment, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750024000702; https://doaj.org/toc/2214-7500

Access URL: https://doaj.org/article/c781016cddb04b2cb8d93457852f77e3

Low circulating levels of neuregulin 4 as a potential biomarker associated with the severity and prognosis of obesity-related metabolic diseases: a systematic review

Authors: Khanyisani Ziqubu, Phiwayinkosi V. Dludla, Sinenhlanhla X.H. Mthembu, Bongani Nkambule, Sithandiwe E. Mazibuko-Mbeje

Source: Adipocyte, Vol 13, Iss 1 (2024)

Subject Terms: Neuregulin 4, brown adipose tissue, obesity, diabetes mellitus, cardiovascular diseases, non-alcoholic fatty liver disease, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Cytology, QH573-671, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3945; https://doaj.org/toc/2162-397X

Access URL: https://doaj.org/article/d8c959f40aed48db946d7ec3931f840f

Persistent behavioural consequences of chronic adolescent cannabidiol (CBD) in a mouse model with increased susceptibility to Δ9-tetrahydrocannabinol and schizophrenia

Authors: Visini, Gabriela, Chesworth, Rose ^{⁎, 1}, Karl, Tim ^{⁎, 1}

Source: In Progress in Neuropsychopharmacology & Biological Psychiatry 2 April 2025 138

Neuregulin1 Attenuates H2O2-Induced Reductions in EAAC1 Protein Levels and Reduces H2O2-Induced Oxidative Stress.

Authors: Lee, Jun-Ho¹, Yoo, Ji-Young², Kim, Han-byeol², Yoo, Hong-Il², Song, Dae-Yong², Min, Sun Seek³, Baik, Tai-Kyoung² tkbaik@eulji.ac.kr, Woo, Ran-Sook² rswoo@eulji.ac.kr

Source: Neurotoxicity Research. Feb2019, Vol. 35 Issue 2, p401-409. 9p.

Subject Terms: *NEUREGULIN receptors, *LACTATE dehydrogenase, *OXIDATIVE stress, *ANTIOXIDANTS, *SUPEROXIDE dismutase, *CATALYTIC oxidation

Neuregulin-4 alleviates isoproterenol (ISO)-induced cardial remodeling by inhibiting inflammation and apoptosis via AMPK/NF-κB pathway

Authors: Wei, Huiqing ^a, Guo, Xiaohua ^a, Yan, Jie ^a, Tian, Xiaochao ^a, Yang, Wenhui ^a, Cui, Kun ^a, Wang, Lijie ^a, Guo, Bingyan ^{a, b, ⁎}

Source: In International Immunopharmacology 25 December 2024 143 Part 2

Immobilized NRG1 Accelerates Neural Crest like Cell Differentiation Toward Functional Schwann Cells Through Sustained Erk1/2 Activation and YAP/TAZ Nuclear Translocation

Authors: Georgios Tseropoulos, Pihu Mehrotra, Ashis Kumer Podder, Emma Wilson, Yali Zhang, Jianmin Wang, Alison Koontz, Nan Papili Gao, Rudiyanto Gunawan, Song Liu, Laura M. Feltri, Marianne E. Bronner, Stelios T. Andreadis

Source: Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)

Subject Terms: chick embryo, demyelinating diseases, neural crest stem cells, neuregulin, schwann cells, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/42ef817889b942149013f1f69c71619c

Neuregulin-1 accelerates corneal epithelial wound healing.

Authors: Jeong, Won-Yong¹, Yoo, Hye-Young¹, Kim, Chan-Wha¹ cwkim@korea.ac.kr

Source: Growth Factors. Dec2017, Vol. 35 Issue 6, p225-233. 9p.

Subject Terms: *NEUREGULIN receptors, *EPITHELIAL cells, *GENE expression, *REGENERATION (Biology), *CELL adhesion

Research progress of novel adipokines in obesity and type 2 diabetes mellitus

Authors: ZHANG Yuling, LONG Min

Source: Zhongguo linchuang yanjiu, Vol 36, Iss 12, Pp 1769-1775 (2023)

Subject Terms: obesity, type 2 diabetes mellitus, novel adipokine, neuregulin 4, asprosin, meteorinlike, Medicine

File Description: electronic resource

Relation: http://zglcyj.ijournals.cn/zglcyj/ch/reader/create_pdf.aspx?file_no=20231201; https://doaj.org/toc/1674-8182

Access URL: https://doaj.org/article/8210d04153554087a36574977a8ba8c3

The Signaling of Neuregulin-Epidermal Growth Factor Receptors and Its Impact on the Nervous System

Authors: Marzia Tagliaferro, Donatella Ponti

Source: Neuroglia, Vol 4, Iss 4, Pp 253-274 (2023)

Subject Terms: ErbB receptors, ErbB3, glioblastoma, glioma, neuregulin, brain, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.mdpi.com/2571-6980/4/4/18; https://doaj.org/toc/2571-6980

Access URL: https://doaj.org/article/55d122d1e00a41f1b2512680adc82620

Research progress on neuregulin 4 regulating lipid metabolism

Authors: WANG Xueran, TIAN Zongyuan, LIU Ruixia

Source: Jichu yixue yu linchuang, Vol 43, Iss 10, Pp 1599-1603 (2023)

Subject Terms: neuregulin 4(nrg4), lipid metabolism, adipose tissue, Medicine

File Description: electronic resource

Relation: http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2023-43-10-1599.pdf; https://doaj.org/toc/1001-6325

Access URL: https://doaj.org/article/409b236129614d46b6e437a45b7416ef

The case for neuregulin-1 as a clinical treatment for stroke

Authors: Jessica M. Noll, Arya A. Sherafat, Gregory D. Ford, Byron D. Ford

Source: Frontiers in Cellular Neuroscience, Vol 18 (2024)

Subject Terms: clinical trial, excitotoxicity, inflammation, ischemia, neuregulin, neuroprotection, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fncel.2024.1325630/full; https://doaj.org/toc/1662-5102

Access URL: https://doaj.org/article/079a6683b7ec434eb27a69e64b194afa

State of the Art in Idiopathic Pulmonary Fibrosis

Contributors: Wygrecka, Malgorzata, El Agha, Elie

Subject Terms: interstitial fibrosis, lung, alveolar fibroelastosis, idiopathic pulmonary fibrosis, pirfenidone, nintedanib, discontinuation, body mass index, adverse event, antifibrotic treatment, IPF, alveolar epithelial cells, intermediate epithelial cells, transitional states, LysoTracker, flow cytometry, lung transcriptomic profile, CK5, NGFR, CD24, epidermal growth factor, epidermal growth factor receptor, ErbB-signaling, pulmonary fibrosis, lung fibrosis, tyrosine kinase inhibitor, TGF-α, TGF-β, amphiregulin, neuregulin 1, basal cells, bronchial epithelium, airway epithelium, MUC5B, single cell RNA sequencing, epithelial populations, antibody folding, immunophilin, interstitial lung disease, ER stress, tacrolimus, FK506-binding protein, peptidyl-prolyl isomerase, 3D cultures, IPF modelling, drug screening, idiopathic pulmonary fibrosis (IPF), histone deacetylase (HDAC), histone acetylation, non-histone protein acetylation, fibroblast-to-myofibroblast differentiation (FMD), type-II alveolar epithelial cell (AECII), bronchiolar basal cells, bronchiolization, Class I-HDAC-inhibitor, (pan-)HDAC-inhibitor, IGF1, IGF1R, lung development, bleomycin-induced pulmonary fibrosis, bleomycin, recombinant FGF10, alveolar epithelial progenitors, AT2 cells, Medicine and Nursing

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Access URL: https://directory.doabooks.org/handle/20.500.12854/96676
https://mdpi.com/books/pdfview/book/6621

Translational Aspects of Cardiovascular Biology

Contributors: Santulli, Gaetano

Subject Terms: cardiovascular disease, vaccine, clinical trials, translational medicine, atherosclerosis, oxLDL, phosphorylcholine, RBP-4, insulin resistance, severity of CAD, T2D, atherosclerotic CAD, endothelial dysfunction, hypoxia, HIF-1α, mitochondria, oxidative stress, inflammation, cardiovascular diseases, cancer, therapeutic target, extracellular NAD+ metabolism, extracellular NMN metabolism, vascular endothelial cells, CD38, CD73, myocardial infarction, neuregulin, glial growth factor 2, pre-clinical therapy, skeletal muscle, gene expression, RNA sequencing, inflammatory bowel disease, limb ischemia, endothelial function, ROS, acute myocardial infarction, diabetes, lactic acid, carbonic anhydrase, CD34, endothelial cells, ERG, hypothermic oxygenated perfusion, liver transplantation, machine perfusion, nestin, VEGFR, IDH1, foam cell, macrophage, ferroptosis, NRF2, atrial fibrillation, obesity, immune infiltration, biomarkers, cardiac fibrosis, lncRNAs, TGF-β, ECMs, exosome, red blood cells, chemotherapy, anemia, microcirculation, laser diffraction, osmotic fragility test, microfluidics, valvular heart disease, degenerative aortic valve stenosis, irisin, periostin, osteoglycin, IL-18, HMGB-1, PCSK9, blood–brain barrier, blood pressure, cerebrovascular disease, hBMECs, hypertension, HUVEC, microRNA, miRNA, miR-4432-3p, Medicine and Nursing, Cardiovascular medicine

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Access URL: https://directory.doabooks.org/handle/20.500.12854/100829
https://mdpi.com/books/pdfview/book/7292

Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agentinduced delayed neuronal injury.

Authors: Yonggang Li¹, Lein, Pamela J.², Ford, Gregory D.³, Cuimei Liu^1,4, Stovall, Kyndra C.^1,3,5, White, Todd E.¹, Bruun, Donald A.², Tewolde, Teclemichael¹, Gates, Alicia S.¹, Distel, Timothy J.¹, Surles-Zeigler, Monique C.¹, Ford, Byron D.¹ bford@msm.edu

Source: Journal of Neuroinflammation. 2015, Vol. 12 Issue 1, p1-13. 13p.

Subject Terms: *NEUREGULIN receptors, *ANIMAL models in research, *BRAIN injuries, *GENE expression, *NEUROTOXICOLOGY

Association of Neuregulin-4 levels and body mass index with hyperandrogenism in Polycystic Ovary Syndrome patients

Authors: mustafa Mutashar, Dr. Manal Kamal Rasheed, Dr. Afraa Mahjoba Al-Naddawi

Source: مجلة كلية الطب, Vol 65, Iss 4 (2024)

Subject Terms: Neuregulin 4, BMI, Polycystic Ovary Syndrome, Free testosterone, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/2140; https://doaj.org/toc/0041-9419; https://doaj.org/toc/2410-8057

Access URL: https://doaj.org/article/a097f4ec3cc74f3baab0dfa028545378

The relationship of circulating neuregulin 4 and irisin, and traditional and novel cardiometabolic risk factors with the risk and severity of coronary artery disease

Authors: Alipoor, Elham ^a, Hosseinzadeh‐Attar, Mohammad Javad ^{a, b, ⁎}, Vasheghani-Farahani, Ali ^{a, c}, Salmani, Mahnaz ^b, Rezaei, Mahsa ^b, Namkhah, Zahra ^d, Ahmadpanahi, Monireh ^b, Jenab, Yaser ^e, Alidoosti, Mohammad ^e, Yaseri, Mehdi ^{f, ⁎}

Source: In Cytokine October 2023 170