Real-World Treatment Patterns and Outcomes Among Patients with Early Non-Small Cell Lung Cancer.

Authors: Deem, Jennifer D.¹ (AUTHOR) dezet74@uw.edu, Hepp, Zsolt² (AUTHOR), Carlson, Joshua J.¹ (AUTHOR)

Source: Current Oncology. Apr2025, Vol. 32 Issue 4, p239. 18p.

Subject Terms: *NON-small-cell lung carcinoma, *NEOADJUVANT chemotherapy, *TREATMENT effectiveness, *COMBINED modality therapy, *ADJUVANT treatment of cancer, *THERAPEUTICS, *LUNG cancer

Geographic Terms: UNITED States

Construction of a Nomogram Model for Predicting Pathologic Complete Response in Breast Cancer Neoadjuvant Chemotherapy Based on the Pan-Immune Inflammation Value.

Authors: Tian, Zhuowan¹ (AUTHOR), Xi, Yiqing² (AUTHOR), Chen, Mengting^1,3 (AUTHOR), Hu, Meishun¹ (AUTHOR), Chen, Fangfang¹ (AUTHOR), Wei, Lei³ (AUTHOR), Zhang, Jingwei¹ (AUTHOR) zjwzhang68@whu.edu.cn

Source: Current Oncology. Apr2025, Vol. 32 Issue 4, p194. 17p.

Subject Terms: *BREAST cancer, *NEOADJUVANT chemotherapy, *FORECASTING, *PATHOLOGIC complete response, *RETROSPECTIVE studies, *PROGNOSTIC models, *THERAPEUTICS, *BIOMARKERS

Predictors of pathological complete response after total neoadjuvant treatment using short course radiotherapy for locally advanced rectal cancer.

Authors: Yacoub, Haythem^1,2 (AUTHOR) yacoubhaythem@hotmail.com, Zenzri, Yosr^2,3 (AUTHOR), Cherif, Dhouha^1,2 (AUTHOR), Ben Mansour, Hajer^2,3 (AUTHOR), Attia, Najla^2,4 (AUTHOR), Mokrani, Cyrine^2,4 (AUTHOR), Ben Zid, Khadija^2,4 (AUTHOR), Letaief, Feryel^2,3 (AUTHOR), Maamouri, Nadia^2,3 (AUTHOR), Mezlini, Amel^2,3 (AUTHOR)

Source: BMC Gastroenterology. 3/31/2025, Vol. 25 Issue 1, p1-8. 8p.

Subject Terms: *NEOADJUVANT chemotherapy, *INDUCTION chemotherapy, *LOGISTIC regression analysis, *MEDICAL sciences, *RECTAL cancer

Spatial relationships and interactions of immune cell niches are linked to the pathologic response of muscle-invasive bladder cancer to neoadjuvant therapy.

Authors: Wahafu, Wasilijiang^1,2 (AUTHOR), Zhou, Quan³ (AUTHOR), Yang, Xihua⁴ (AUTHOR), Yang, Yongming⁴ (AUTHOR), Zhao, Yuanyuan⁵ (AUTHOR), Wang, Zhu² (AUTHOR), Kang, Xiangpeng² (AUTHOR), Ye, Xiongjun¹ (AUTHOR), Xing, Nianzeng^1,2 (AUTHOR) xingnianzeng@126.com

Source: Journal of Translational Medicine. 3/27/2025, Vol. 23 Issue 1, p1-16. 16p.

Subject Terms: *MEDICAL sciences, *NEOADJUVANT chemotherapy, *CANCER invasiveness, *TUMOR microenvironment, *TERTIARY structure

Shortcoming of ypStage staging system: Lack of differentiation for preoperative treatment.

Authors: Du, Peizhun¹ (AUTHOR), Zhou, Jinzhe² (AUTHOR), Liu, Pengcheng¹ (AUTHOR), Huang, Guangjian¹ (AUTHOR) gjhuang@fudan.edu.cn, Hu, Cheng'en¹ (AUTHOR) stevenhu76@hotmail.com

Source: PLoS ONE. 3/13/2025, Vol. 20 Issue 3, p1-9. 9p.

Subject Terms: *STATISTICAL significance, *NEOADJUVANT chemotherapy, *CANCER prognosis, *REGRESSION analysis, *PROGNOSIS, *SURVIVAL analysis (Biometry)

Association of Preoperative Sarcopenia with the Risk of Anastomotic Leakage in Surgical Esophageal Cancer Patients: A Meta-Analysis.

Authors: Tian, Long¹ (AUTHOR), Wang, Yan² (AUTHOR), Che, Guowei¹ (AUTHOR) cheguoweixw@126.com

Source: Nutrition & Cancer. Mar2025, p1-8. 8p. 4 Illustrations.

Subject Terms: *NEOADJUVANT chemotherapy, *DISEASE risk factors, *ESOPHAGEAL cancer, *SCIENCE databases, *WEB databases, *SARCOPENIA

Sequential Changes in Circulating Tumor Cells in the Peripheral Blood of Pancreatic Cancer Patients with Preoperative Chemotherapy Using a New Immunocytology-Based, Light Microscopic CTC Detection Platform.

Authors: Yasui, Kohei¹ (AUTHOR), Saito, Takuya^1,2 (AUTHOR) saitou.takuya.856@mail.aichi-med-u.ac.jp, Ueda, Sho¹ (AUTHOR), Shinohara, Kentaro^1,2 (AUTHOR), Fukami, Yasuyuki¹ (AUTHOR), Sano, Tsuyoshi¹ (AUTHOR), Nakanishi, Hayao^1,2 (AUTHOR)

Source: Diagnostics (2075-4418). Mar2025, Vol. 15 Issue 6, p752. 12p.

Subject Terms: *NEOADJUVANT chemotherapy, *DRUG resistance in cancer cells, *CANCER chemotherapy, *PANCREATIC cancer, *CANCER patients, *XENOGRAFTS

Prognostic role of STMN1 expression and neoadjuvant therapy efficacy in breast cancer.

Authors: Qian, Li^1,2 (AUTHOR), Cairong, Zhu^1,2 (AUTHOR), Yongdong, Liao^1,2 (AUTHOR), Quan, Li^1,2 (AUTHOR), Haihu, Zhong^1,2 (AUTHOR), Xiaofeng, Zhu^1,2 (AUTHOR), Xuan, Ye^1,2 (AUTHOR), Yongcheng, Chen³ (AUTHOR), Kai, Chen^4,5 (AUTHOR) chenkai23@mail.sysu.edu.cn, Guanming, Lu³ (AUTHOR) luguanming@yeah.net, Jie, Li^1,2 (AUTHOR) lijie2958@gwcmc.org

Source: BMC Cancer. 3/13/2025, Vol. 25 Issue 1, p1-13. 13p.

Subject Terms: *GENE expression, *NEOADJUVANT chemotherapy, *MEDICAL sciences, *BREAST cancer prognosis, *BREAST cancer

Safety and efficacy of genomic biomarker-guided neoadjuvant therapy for locally advanced and oligometastatic prostate cancer (SEGNO): study protocol for an open-label prospective phase II umbrella clinical trial.

Authors: Huang, Haichao¹ (AUTHOR), Wang, Tao¹ (AUTHOR), Li, Wei¹ (AUTHOR), Wu, Zhun¹ (AUTHOR), Wang, Xuegang¹ (AUTHOR), Xing, Jinchun¹ (AUTHOR), Chen, Bin^1,2 (AUTHOR) chenbin5557@163.com, Zhang, Kaiyan^1,2 (AUTHOR) Kaiyanzhang_xmu@163.com

Source: BMC Cancer. 3/10/2025, Vol. 25 Issue 1, p1-6. 6p.

Subject Terms: *PATHOLOGIC complete response, *NEOADJUVANT chemotherapy, *MEDICAL sciences, *SURVIVAL rate, *OVERALL survival

Comprehensive evaluation of tumor response better evaluates the efficacy of neoadjuvant chemotherapy and predicts the prognosis in gastric cancer - a post hoc analysis of a single-center randomized controlled trial.

Authors: Gan, Xuejun¹ (AUTHOR), Jia, Yongning² (AUTHOR), Shan, Fei² (AUTHOR), Ying, Xiangji¹ (AUTHOR), Li, Shuangxi¹ (AUTHOR), Zhang, Yan¹ (AUTHOR), Pang, Fei¹ (AUTHOR), Li, Ziyu¹ (AUTHOR) ziyu_li@hsc.pku.edu.cn

Source: BMC Cancer. 3/5/2025, Vol. 25 Issue 1, p1-13. 13p.

Subject Terms: *MEDICAL sciences, *NEOADJUVANT chemotherapy, *TUMOR markers, *GASTRECTOMY, *STOMACH cancer

Patient-Derived Organoids for Guiding Neoadjuvant Chemotherapy in Bilateral Primary Breast Cancer: A Case Report.

Authors: Cao, Meng (AUTHOR), Wang, Rong (AUTHOR), Cheng, Xiaohan (AUTHOR), Yu, Huiping (AUTHOR), Tong, Qi (AUTHOR), Yao, Yongzhong (AUTHOR)

Source: OncoTargets & Therapy. Mar2025, Vol. 18, p319-324. 6p.

Subject Terms: *METASTATIC breast cancer, *NEOADJUVANT chemotherapy, *BREAST cancer, *LYMPHATIC metastasis, *CANCER invasiveness

Efficacy and Safety of Perioperative Immunotherapy for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Network Meta-Analysis.

Authors: Du, Zhijuan^1,2 (AUTHOR), Chen, Siyuan^1,2 (AUTHOR), Qin, Yuhui^1,2,3 (AUTHOR), Lv, Yahui^1,2,4 (AUTHOR), Du, Xiangyu^1,2 (AUTHOR), Yu, Heying³ (AUTHOR), Liu, Zhefeng⁴ (AUTHOR) lzf1220@sina.com

Source: Current Oncology. Mar2025, Vol. 32 Issue 3, p184. 13p.

Subject Terms: *NON-small-cell lung carcinoma, *NEOADJUVANT chemotherapy, *SUBGROUP analysis (Experimental design), *TREATMENT effectiveness, *RANDOMIZED controlled trials, *IMMUNOLOGICAL adjuvants, *SAFETY

Role of Pelvic Ultrasound in Predicting the Response to Neoadjuvant Chemotherapy in Locally Advanced Cervical Cancer.

Authors: Perniola, Giorgia¹ (AUTHOR) giorgia.perniola@uniroma1.it, Paoni Saccone, Giulia¹ (AUTHOR) giulia.paonisaccone@uniroma1.it, Tonti, Noemi¹ (AUTHOR) federica.tanzi@uniroma1.it, Tanzi, Federica¹ (AUTHOR) innocenza.palaia@uniroma1.it, Palaia, Innocenza¹ (AUTHOR) violante.didonato@uniroma1.it, Di Donato, Violante¹ (AUTHOR) federica.tomao@uniroma1.it, Tomao, Federica¹ (AUTHOR) ludovico.muzii@uniroma1.it, Muzii, Ludovico¹ (AUTHOR) ilaria.cuccu@uniroma1.it, Bogani, Giorgio² (AUTHOR) giorgio.bogani@istitutotumori.mi.it, Cuccu, Ilaria¹ (AUTHOR) giusi.santangelo@uniroma1.it, Ciminello, Enrico³ (AUTHOR) enrico.ciminello@iss.it, Battaglia, Francesco Antonio⁴ (AUTHOR) franbatt@alice.it, Santangelo, Giusi¹ (AUTHOR)

Source: Diagnostics (2075-4418). Feb2025, Vol. 15 Issue 4, p463. 11p.

Subject Terms: *NEOADJUVANT chemotherapy, *CERVICAL cancer, *SENSITIVITY & specificity (Statistics), *RADIOISOTOPE brachytherapy, *ULTRASONIC imaging, *UTERINE artery

Most oncological pancreas resections must consider the mesopancreas.

Authors: Safi, S. A.¹ (AUTHOR), David, S.¹ (AUTHOR), Haeberle, L.² (AUTHOR), Vaghiri, S.¹ (AUTHOR), Luedde, T.³ (AUTHOR), Roderburg, C.³ (AUTHOR), Esposito, I.² (AUTHOR), Fluegen, G.¹ (AUTHOR), Knoefel, W. T.¹ (AUTHOR) knoefel@hhu.de

Source: BMC Cancer. 2/4/2025, Vol. 25 Issue 1, p1-9. 9p.

Subject Terms: *NEOADJUVANT chemotherapy, *SURGICAL margin, *PANCREATIC duct, *PANCREATIC cancer, *PANCREATICODUODENECTOMY

Gamma-Glutamyl Transferase Plus Carcinoembryonic Antigen Ratio Index: A Promising Biomarker Associated with Treatment Response to Neoadjuvant Chemotherapy for Patients with Colorectal Cancer Liver Metastases.

Authors: Yin, Yanjiang^1,2 (AUTHOR), Xu, Bowen^1,2,3 (AUTHOR) xubowen1112@126.com, Chang, Jianping^1,3 (AUTHOR), Li, Zhiyu^1,4 (AUTHOR), Bi, Xinyu¹ (AUTHOR), Wei, Zhicheng⁴ (AUTHOR), Che, Xu⁴ (AUTHOR), Cai, Jianqiang^1,2 (AUTHOR) caijianqiangcicams@126.com

Source: Current Oncology. Feb2025, Vol. 32 Issue 2, p117. 14p.

Subject Terms: *NEOADJUVANT chemotherapy, *BIOMARKERS, *LIVER metastasis, *MACHINE learning, *COLORECTAL cancer, *GAMMA-glutamyltransferase, *PREDICTION models, *CARCINOEMBRYONIC antigen

Measurement of Intratumor Heterogeneity and Its Changing Pattern to Predict Response and Recurrence Risk After Neoadjuvant Chemotherapy in Breast Cancer.

Authors: Zhu, Mingxi¹ (AUTHOR), Wu, Qiong^1,2 (AUTHOR), Geng, Xiaochuan^2,3 (AUTHOR), Xie, Huaying³ (AUTHOR), Wang, Yan¹ (AUTHOR), Wu, Ziping¹ (AUTHOR), Lin, Yanping¹ (AUTHOR), Zhou, Liheng¹ (AUTHOR), Xu, Shuguang¹ (AUTHOR), Ye, Yumei¹ (AUTHOR), Yin, Wenjin¹ (AUTHOR), Hua, Jia² (AUTHOR) xiehuaying@renji.com, Lu, Jingsong¹ (AUTHOR) huajia@renji.com, Wang, Yaohui¹ (AUTHOR)

Source: Current Oncology. Feb2025, Vol. 32 Issue 2, p93. 14p.

Subject Terms: *BREAST cancer, *NEOADJUVANT chemotherapy, *PHENOTYPIC plasticity, *INDIVIDUALIZED medicine, *DISEASE remission, *DISEASE relapse, *MAGNETIC resonance imaging

Radical Prostatectomy in Multimodal Setting: Current Role of Neoadjuvant and Adjuvant Hormonal or Chemotherapy-Based Treatments.

Authors: Oderda, Marco¹ (AUTHOR) marco.oderda@unito.it, Calleris, Giorgio^1,2 (AUTHOR), Iorio, Giuseppe Carlo^2,3 (AUTHOR), Simone, Giuseppe³ (AUTHOR), Gontero, Paolo¹ (AUTHOR)

Source: Current Oncology. Feb2025, Vol. 32 Issue 2, p92. 11p.

Subject Terms: *PROSTATE cancer, *NEOADJUVANT chemotherapy, *ADJUVANT treatment of cancer, *CANCER prognosis, *RADICAL prostatectomy, *CANCER chemotherapy, *ANDROGEN receptors, *HORMONE therapy

Concurrent Neoadjuvant Chemotherapy and Radiation in Locally Advanced Breast Cancer: Impact on Locoregional Recurrence Rates.

Authors: Grindrod, Natalie^1,2 (AUTHOR), Cecchini, Matthew^1,2 (AUTHOR), Brackstone, Muriel^1,3 (AUTHOR) muriel.brackstone@lhsc.on.ca

Source: Current Oncology. Feb2025, Vol. 32 Issue 2, p85. 11p.

Subject Terms: *NEOADJUVANT chemotherapy, *RADIOTHERAPY, *CLINICAL trials, *TUMOR-infiltrating immune cells, *TREATMENT effectiveness, *HISTOPATHOLOGY, *DISEASE relapse, *METASTATIC breast cancer

Efficacy and safety of neoadjuvant bevacizumab plus chemotherapy in locally advanced gastric cancer patients: a retrospective, comparative study.

Authors: Yin, Bin¹ (AUTHOR), Luo, Wei² (AUTHOR) luowei@hnca.org.cn

Source: World Journal of Surgical Oncology. 1/28/2025, Vol. 23 Issue 1, p1-8. 8p.

Subject Terms: *NEOADJUVANT chemotherapy, *STOMACH cancer, *MEDICAL sciences, *OVERALL survival, *PROGRESSION-free survival

Neoadjuvant Chemotherapy for T3 Tumors in the Era of Precision Medicine—Biology Is Still King.

Authors: Rahman, Rakhshanda Layeequr¹ (AUTHOR) rrahman2@metrohealth.org, Santillan, Alfredo² (AUTHOR), Habibi, Mehran³ (AUTHOR), Beitsch, Peter⁴ (AUTHOR), Whitworth, Pat⁵ (AUTHOR), Ramaswamy, Harshini⁶ (AUTHOR) william.audeh@agendia.com, Chmielewski-Stivers, Nicole⁶ (AUTHOR), Menicucci, Andrea⁶ (AUTHOR), Audeh, William⁶ (AUTHOR), O'Shaughnessy, Joyce⁷ (AUTHOR)

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p491. 9p.

Subject Terms: *NEOADJUVANT chemotherapy, *ODDS ratio, *BREAST cancer, *ONCOLOGY, *CANCER chemotherapy, *BREAST