Method development and validation for determination of N-Nitrosamines in pharmaceutical preparations by LC-MS/MS: Application to extractables and leachables studies

Authors: Dalkılıç, Oğuzhan ^a, Demircioğlu, İbrahim Hakkı ^a, Çelik, Saffet ^b, Can, Hasan ^c, Akman, Tugrul Cagri ^d, Atila, Alptuğ ^{c, e, ⁎}, Kılıç, Hamdullah ^{c, f}, Kandemir, Levent ^a

Source: In Journal of Chromatography A 29 March 2025 1745

Occurrence, fate, and transport of N-nitrosamines and precursors in sewage treatment plants and receiving rivers in a highly urbanized basin

Authors: Liu, Jie ^a, Zhao, Bo ^{a, ⁎}, Wang, Longfei ^a, Zhang, Wenlong ^a, Zan, Tingchao ^b, Chen, Zhenguo ^{c, d}, Li, Yi ^{a, ⁎⁎}

Source: In Environmental Pollution 1 March 2025 368

Oxidative coupling of N-nitrosoanilines with substituted allyl alcohols under rhodium (III) catalysis

Authors: Priyanka Chaudhary

Source: Frontiers in Chemistry, Vol 12 (2024)

Subject Terms: N-nitrosamines, oxidative coupling, allyl alcohols, rhodium (III) catalysis, C-H activation and functionalization, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fchem.2024.1506493/full; https://doaj.org/toc/2296-2646

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Synergism of Fusobacterium periodonticum and N-nitrosamines promote the formation of EMT subtypes in ESCC by modulating Wnt3a palmitoylation

Authors: Mingjun Sun, Zhenyan Peng, Weitao Shen, Xinxin Guo, Yinghao Liao, Yang Huang, Ping Ye, Mohan Hu, Qiang Lin, Ran Liu

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Esophageal squamous cell carcinoma, N-Nitrosamines, Fusobacterium periodonticum, FadAL, Palmitoylation, Epithelial-mesenchymal transition, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/410971be972a48aeac57d8e98392aec2

Formation of advanced glycation end-products and N-nitrosamines in salami of different recipes and fermented at different stages

Authors: Wang, Wenjing ¹, Song, Zixiong ¹, Jing, Ying, Wei, Xiaoxiao, Li, Haizhen, Xie, Jianhua, Shen, Mingyue ^⁎

Source: In Food Chemistry 15 May 2025 474

Metabolic activation of short-chain alkyl N-nitrosamines using Aroclor 1254 or phenobarbital/beta-naphthoflavone-induced rat or hamster S9 – A comparative analysis

Authors: Jessica Dieckhoff, Frank Bringezu, Stephanie Simon

Source: Toxicology Reports, Vol 12, Iss , Pp 215-223 (2024)

Subject Terms: N-Nitrosamines, Bacterial Reverse Mutation Assay, Rat liver S9, Hamster liver S9, uninduced S9, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221475002400012X; https://doaj.org/toc/2214-7500

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Preparation of ortho-hydroxyl/carboxyl dual-functionalized hypercrosslinked polymers for highly efficient enrichment of nitrosamines with broad polarity prior to gas chromatography-mass spectrometry analysis

Authors: Yang, Kai, Zhang, Xiaoqing, Shen, Jiwei, Wei, Yinmao, Wang, Chaozhan ^⁎

Source: In Journal of Hazardous Materials 5 December 2024 480

Variability in addictive and carcinogenic potential of smokeless tobacco products marketed in Mumbai, India: a surveillance studyResearch in context

Authors: Sampada S. Nikam, Vikram Gota, Prakash C. Gupta, Namrata Puntambekar, Arjun Singh, Pankaj Chaturvedi, Peter W. Villalta, Dorothy K. Hatsukami, Jasjit S. Ahluwalia, Saonli Basu, Samir S. Khariwala, Irina Stepanov

Source: The Lancet Regional Health - Southeast Asia, Vol 29, Iss , Pp 100457- (2024)

Subject Terms: Smokeless tobacco, Carcinogens, Nicotine, Tobacco-specific N-Nitrosamines, India, Tobacco control, Public aspects of medicine, RA1-1270

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Relation: http://www.sciencedirect.com/science/article/pii/S2772368224001070; https://doaj.org/toc/2772-3682

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Fate of quaternary ammonium compounds upon the UV/monochloramine process: Kinetics, transformation pathways and the formation of N-nitroso-N-methyl-N-alkylamines

Authors: Kong, Angel Wing-Yin ^a, Law, Japhet Cheuk-Fung ^a, Leung, Kelvin Sze-Yin ^{a, b, ⁎}

Source: In Journal of Hazardous Materials 5 October 2024 478

Residual Nitrite, Nitrate, and Volatile N-Nitrosamines in Organic and Conventional Ham and Salami Products

Authors: Kathrine H. Bak, Susanne Bauer, Christoph Eisenreich, Peter Paulsen

Source: Foods, Vol 14, Iss 1, p 112 (2025)

Subject Terms: cured meat, curing, human health, microbial safety, processed meat, volatile N-nitrosamines, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://www.mdpi.com/2304-8158/14/1/112; https://doaj.org/toc/2304-8158

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Investigation of the Formaldehyde-Catalyzed N[sbnd]Nitrosation of Dialkyl Amines: An Automated Experimental and Kinetic Modelling Study Using Dibutylamine

Authors: Diab, Samir ^{a, ⁎}, Ferrini, Paola ^b, Dominey, Andrew P. ^b, Whiting, Matthew P. ^b, Wickens, James R. ^b, Ashworth, Ian W. ^c, Rainey, Trevor J. ^d

Source: In Journal of Pharmaceutical Sciences June 2024 113(6):1624-1635

Levels of nitrate, nitrite and nitrosamines in model sausages during heat treatment and in vitro digestion – The impact of adding nitrite and spinach (Spinacia oleracea L.)

Authors: Niklas, Agnieszka A. ^{a, ⁎}, Borge, Grethe Iren A. ^b, Rødbotten, Rune ^b, Berget, Ingunn ^b, Müller, Mette H.B. ^c, Herrmann, Susan S. ^a, Granby, Kit ^a, Kirkhus, Bente ^b

Source: In Food Research International April 2023 166

Effects of Spice Essential Oils on Quality and Safety of Catfish Surimi Dry Sausages

Authors: Yuting ZHANG, Yu ZHANG, Lizhen MA, Liya LIANG

Source: Shipin gongye ke-ji, Vol 44, Iss 3, Pp 108-115 (2023)

Subject Terms: essential oil of spices, catfish surimi, air dried sausage, quality, biogenic amine, n-nitrosamines, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://doaj.org/toc/1002-0306

Access URL: https://doaj.org/article/05b6a1819ec34df7aae94cf464b0d521

Effects of Inoculating Autochthonous Starter Cultures on Changes of N-Nitrosamines and Their Precursors in Chinese Traditional Fermented Fish during In Vitro Human Digestion

Authors: Han Li, Qian Li, Qi Wang, Jiwang Chen, Wenshui Xia, E Liao

Source: Foods, Vol 13, Iss 13, p 2021 (2024)

Subject Terms: Chinese traditional fermented fish, biogenic amines, nitrite, N-nitrosamines, in vitro human digestion, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://www.mdpi.com/2304-8158/13/13/2021; https://doaj.org/toc/2304-8158

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Maximizing N-Nitrosamine Rejection via RO Membrane Plugging with Hexylamine and Hexamethylenediamine

Authors: Silvia Morović, Katarina Marija Drmić, Sandra Babić, Krešimir Košutić

Source: Nanomaterials, Vol 14, Iss 13, p 1117 (2024)

Subject Terms: N-nitrosamines, RO membranes, molecular plugging, membrane modification, water reuse, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/14/13/1117; https://doaj.org/toc/2079-4991

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Genetic and epigenetic instability induced by betel quid associated chemicals

Authors: Rajendra Bose Muthukumaran, Pritha Bhattacharjee, Priya Bhowmick, Lalrinawma Zote, Malsawmtluangi, Nachimuthu Senthil Kumar, Lalrintluanga Jahau, Marcus S. Cooke, Chiung-Wen Hu, Mu-Rong Chao

Source: Toxicology Reports, Vol 10, Iss , Pp 223-234 (2023)

Subject Terms: Areca nut, Tobacco, Alkaloids, N-nitrosamines, DNA adducts, Epigenetic modifications, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750023000148; https://doaj.org/toc/2214-7500

Access URL: https://doaj.org/article/da9e6729ebe4439a9d2a85fecf2b47f9

Simultaneous determination of 10 N-nitrosamines in drinking water by tandem solid phase extraction-gas chromatography tandem mass spectrometry

Authors: Dengkun LI, Chunjing CHEN, Xiangping LIU, Yun ZHANG, Haiping NI, Lei LI

Source: 环境与职业医学, Vol 39, Iss 8, Pp 924-930 (2022)

Subject Terms: tandem solid phase extraction, gas chromatography tandem mass spectrometry, drinking water, n-nitrosamines, Medicine (General), R5-920, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.jeom.org/article/cn/10.11836/JEOM21505; https://doaj.org/toc/2095-9982

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The Effect of Tobacco Smoke N-Nitrosamines, NNK and NDEA, and Nicotine, on DNA Mismatch Repair Mechanism and miRNA Markers, in Hypopharyngeal Squamous Cell Carcinoma: An In Vivo Model and Clinical Evidence

Authors: Sotirios G. Doukas, Dimitra P. Vageli, Panagiotis G. Doukas, Dragana Nikitovic, Aristidis Tsatsakis, Benjamin L. Judson

Source: Current Oncology, Vol 29, Iss 8, Pp 5531-5549 (2022)

Subject Terms: DNA mismatch repair, tobacco smoke, N-Nitrosamines, NNK, NDEA, nicotine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/29/8/437; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/20c7993c319d4f799cd94fa10e7fd001

Changes in N-nitrosamines, Residual Nitrites, Lipid Oxidation, Biogenic Amines, and Microbiota in Chinese Sausages Following Treatment with Tea Polyphenols and Their Palmitic Acid-modified Derivatives

Authors: Qin Zhou, Min Mo, Anliang Wang, Bobin Tang, Qiang He

Source: Journal of Food Protection, Vol 86, Iss 5, Pp 100072- (2023)

Subject Terms: Biogenic amines, Chinese sausages, Lipid oxidation, Nitrite, N-nitrosamines, Palmitoyl-tea polyphenols, Food processing and manufacture, TP368-456, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0362028X23067443; https://doaj.org/toc/0362-028X

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Risk assessment of N‐nitrosamines in food

Authors: EFSA Panel on Contaminants in the Food Chain (EFSA CONTAM Panel), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús delMazo, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Christiane Vleminckx, Heather Wallace, Benigni Romualdo, Cristina Fortes, Stephen Hecht, Marco Iammarino, Olaf Mosbach‐Schulz, Francesca Riolo, Anna Christodoulidou, Bettina Grasl‐Kraupp

Source: EFSA Journal, Vol 21, Iss 3, Pp n/a-n/a (2023)

Subject Terms: N‐nitrosamines (N‐NAs), cancer, genotoxicity, occurrence, exposure, food, Nutrition. Foods and food supply, TX341-641, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://doaj.org/toc/1831-4732

Access URL: https://doaj.org/article/e273443793d34434ab060cb79c4ee6a6