Fostamatinib alleviates temporomandibular joint osteoarthritis by maintaining cartilage homeostasis through MAPK/NF-κB and AKT/mTOR pathways

Authors: Zhang, Yuxin ^{a, b, 1}, Zhang, Dahe ^{a, 1}, Xu, Qingyu ^a, Xia, Simo ^a, Shen, Pei ^{a, ⁎}, Yang, Chi ^{a, ⁎}

Source: In International Immunopharmacology 6 February 2025 147

A biomimetic targeted nanosystem delivering synergistic inhibitors for glioblastoma immune microenvironment reprogramming and treatment

Authors: Yulei Mu, Zhen Zhang, Huiqun Zhou, Min Jin, Liang Ma, Bangheng Liu, Cheng Ma, Xu Hu, Yi Zhang, Dong-An Wang

Source: Materials Today Bio, Vol 28, Iss , Pp 101222- (2024)

Subject Terms: Glioblastoma, Small-molecule inhibitors, CXCL12/CXCR4 axis, mTOR pathways, Blood-brain barrier, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590006424002837; https://doaj.org/toc/2590-0064

Access URL: https://doaj.org/article/9c81fb243816412694b710f07cab64af

Tongguan capsule for treating myocardial ischemia-reperfusion injury: integrating network pharmacology and mechanism study

Authors: Jiantao Liu, Chunping Liu, Huiqi Chen, Huan Cen, Hailong Yang, Peijian Liu, Fang Liu, Liuling Ma, Quanfu Chen, Lei Wang

Source: Pharmaceutical Biology, Vol 61, Iss 1, Pp 437-448 (2023)

Subject Terms: Hypoxia/reoxygenation, apoptosis, mTOR pathways, autophagy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1388-0209; https://doaj.org/toc/1744-5116

Access URL: https://doaj.org/article/a40cda96a9e74d58a9aed75136b46847

Enhanced apoptotic activity of Pluronic F127 polymer-encapsulated chlorogenic acid nanoparticles through the PI3K/Akt/mTOR signaling pathway in liver cancer cells and in vivo toxicity studies in zebrafish

Authors: Alanazi Fehaid, Elderdery Abozer Y., Alzahrani Badr, Alzerwi Nasser A. N., Althobiti Maryam Musleh, Rayzah Musaed, Alanazi Abdulaziz Suailem, Kuriri Fahd A., Idrees Bandar, Alenazy Fawaz O., Alsultan Afnan, Rayzah Fares, Baksh Yaser, Subbiah Suresh Kumar, Mok Pooi Ling

Source: e-Polymers, Vol 23, Iss 1, Pp 6-411 (2023)

Subject Terms: pluronic f127, chlorogenic acid nanoparticles, hepg2 cell lines, pi3k/akt, mtor pathways, Polymers and polymer manufacture, TP1080-1185

File Description: electronic resource

Relation: https://doaj.org/toc/1618-7229

Access URL: https://doaj.org/article/bd1faa6068a2470883660dae3c2eaf28

The Effects of Different Concentrations of Hydrogen-Rich Water on the Growth Performance, Digestive Ability, Antioxidant Capacity, Glucose Metabolism Pathway, mTOR Signaling Pathway, and Gut Microbiota of Largemouth Bass (Micropterus salmoides)

Authors: Yin Yuan, Huixiang Li, Songwei Chen, Yongchun Lin, Jiangyuan Peng, Junru Hu, Yongsheng Wang

Source: Fishes, Vol 9, Iss 6, p 210 (2024)

Subject Terms: hydrogen rich water, growth performance, glucose metabolism, mTOR pathways, gut microbiota, largemouth bass, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.mdpi.com/2410-3888/9/6/210; https://doaj.org/toc/2410-3888

Access URL: https://doaj.org/article/145696710f5e4acbbd12e37502367d0c

The HIF-1α and mTOR Pathways Amplify Heterotopic Ossification

Authors: Haitao Wang, Frederick S. Kaplan, Robert J. Pignolo

Source: Biomolecules, Vol 14, Iss 2, p 147 (2024)

Subject Terms: fibrodysplasia ossificans progressiva, hypoxia-inducible factor, mechanistic target of rapamycin (mTOR) pathways, heterotopic ossification, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/2/147; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/0ee5486526b04424ab942dfbac84108c

AKT–THE MAMMALIAN TARGET OF RAPAMYCIN (MTOR) PATHWAY INHIBITION INCREASES CERVICAL CANCER CELL CHEMOSENSITIVITY TO ACTIVE FORM OF IRINOTECAN (SN-38)

Authors: Leri Septiani, Yudi Mulyana Hidayat, Yusuf Sulaeman Effendi, Tono Djuwantono, Dimas Erlangga Luftimas, Ahmad Faried

Source: International Journal of Integrated Health Sciences, Vol 1, Iss 1, Pp 13-21 (2015)

Subject Terms: Akt-mTOR pathways anti-neoplastic drugs, cervix cancer cells, LY294002, rapamycin, Medicine

File Description: electronic resource

Relation: http://journal.fk.unpad.ac.id/index.php/ijihs/article/view/103/91; https://doaj.org/toc/2302-1381; https://doaj.org/toc/2338-4506

Access URL: https://doaj.org/article/548d89c32ab344f6b5bc2a529348f4a9

PI3K-mTOR-S6K Signaling Mediates Neuronal Viability via Collapsin Response Mediator Protein-2 Expression

Authors: Eun J. Na, Hye Yeon Nam, Jiyoung Park, Myung Ah Chung, Hyun Ae Woo, Hwa-Jung Kim

Source: Frontiers in Molecular Neuroscience, Vol 10 (2017)

Subject Terms: mTOR pathways, PI3K, CRMP-2, neuronal outgrowth, pentylentetrazole, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fnmol.2017.00288/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/49bf6198903147c3af301b8ff0ec51d9

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