Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics

Authors: Isy Petit, Quentin Faucher, Jean-Sébastien Bernard, Perrine Giunchi, Antoine Humeau, François-Ludovic Sauvage, Pierre Marquet, Nicolas Védrenne, Florent Di Meo

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

Subject Terms: Organ-On-a-Chip, Pharmacokinetics, Drug membrane transporters, Proximal tubule-On-a-Chip, Drug-Drug Interactions, Drug-Endogenous metabolite Interactions, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/cfdf4b852a454451b8699495f37a24ff

Corrigendum: Extracellular vesicles from human breast cancer-resistant cells promote acquired drug resistance and pro-inflammatory macrophage response

Authors: Patrick Santos, Caroline P. Rezende, Renan Piraine, Bianca Oliveira, Francielle B. Ferreira, Vinicius S. Carvalho, Rodrigo T. Calado, Matteo Pellegrini, Fausto Almeida

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: chemoresistance, tamoxifen, doxorubicin, immunomodulation, membrane transporters, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595885/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3dc355c6d22f416cb5a3f99f092f5ebf

Understanding, inhibiting, and engineering membrane transporters with high-throughput mutational screens

Authors: Miller, Silas T. ^{1, 2, 3}, Macdonald, Christian B. ^{2, 4}, Raman, Srivatsan ^{3, 5, 6, ∗}

Source: In Cell Chemical Biology 17 April 2025 32(4):529-541

Waterlogging stress mechanism and membrane transporters in soybean (Glycine max (L.) Merr.)

Authors: Rajendran, Ambika ^{a, 1, ⁎}, Ramlal, Ayyagari ^{a, b, 1}, Harika, Amooru ^c, Subramaniam, Sreeramanan ^{b, d, e}, Raju, Dhandapani ^f, Lal, S.K. ^a

Source: In Plant Physiology and Biochemistry March 2025 220

Sulfur and phosphorus transporters in plants: Integrating mechanisms for optimized nutrient supply

Authors: Singh, Ajey ^a, Khare, Shubhra ^b, Niharika ^a, Gupta, Praveen ^{a, ⁎}

Source: In Plant Physiology and Biochemistry July 2025 224

Membrane Proteins: Function, Structure, and Dynamic

Contributors: Senju, Yosuke, Suetsugu, Shiro

Subject Terms: single-molecule tracking, confinement, plasma membrane, antimicrobial resistance, bacterial proteins, outer membrane proteins, uropathogenic Escherichia coli, membrane proteins, lipid transport, scramblases, ion channels, biological membrane, structure, function, immune response, Entamoeba histolytica, vaccine, cholecystokinin, cholecystokinin receptor, G protein-coupled receptor, positive allosteric modulator, obesity, protein stabilization, disulfide bonds, photosynthetic reaction center, integral membrane protein, site-directed mutagenesis, crystal structure, membrane transporters, protein–lipid interactions, Bor1, SLC4A1, yeast, bilayer lipid membranes, cytochrome c, electrical conductance, lipid pores, G-protein-coupled-receptors, GPCRs, membrane protein, sterols, cholesterol, class C GPCRs, synaptotagmin, SNARE complex, complexin, lipid bilayers, exocytosis, neuronal transmitters, transmembrane proteins, dimerization, cancer immunotherapy, small-molecule drugs, dimerization regulation, interfacial enzymes, fatty acid metabolism, peripheral membrane proteins, membrane binding, mechanism, Applied mathematics

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/137514
https://mdpi.com/books/pdfview/book/8673

Extracellular vesicles from human breast cancer-resistant cells promote acquired drug resistance and pro-inflammatory macrophage response

Authors: Patrick Santos, Caroline P. Rezende, Renan Piraine, Bianca Oliveira, Francielle B. Ferreira, Vinicius S. Carvalho, Rodrigo T. Calado, Matteo Pellegrini, Fausto Almeida

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: chemoresistance, tamoxifen, doxorubicin, immunomodulation, membrane transporters, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1468229/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9fe98e93046d4cd79ee572cf27a180c9

Modified plant‐derived exosomes: Precision medicine in cancer treatment

Authors: Swastika Maitra, Subham Sarkar, Bikram Dhara

Source: Clinical and Translational Discovery, Vol 4, Iss 4, Pp n/a-n/a (2024)

Subject Terms: cancer therapy, mammalian derived exosome, membrane transporters, nanomedicine, plant derived exosome, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2768-0622

Access URL: https://doaj.org/article/2d9f4fef781049b983cfde8f35f98b97

Determining expression changes of ANO7 and SLC38A4 membrane transporters in colorectal cancer

Authors: Khosroshahi, Elaheh Mohandesi ^{a, b, 1}, Maghsoudloo, Mazaher ^{c, 1}, Fahimi, Hossein ^{a, b}, Mokhtari, Khatere ^d, Entezari, Maliheh ^{b, a, ⁎⁎}, Peymani, Maryam ^{e, ⁎⁎⁎}, Hashemi, Mehrdad ^{a, b, ⁎⁎⁎⁎}, Wan, Runlan ^{f, g, ⁎}

Source: In Heliyon 30 July 2024 10(14)

Seasonal patterns in microbial carbon and iron transporter expression in the Southern Ocean

Authors: Pavla Debeljak, Barbara Bayer, Ying Sun, Gerhard J. Herndl, Ingrid Obernosterer

Source: Microbiome, Vol 11, Iss 1, Pp 1-12 (2023)

Subject Terms: Prokaryotic membrane transporters, Organic substrate utilization, Iron uptake, Metatranscriptomics, Metaproteomics, Metagenome-assembled genomes, Microbial ecology, QR100-130

File Description: electronic resource

Relation: https://doaj.org/toc/2049-2618

Access URL: https://doaj.org/article/b7dfe6cb1dba4f07af239d0b4e978476

Mechanisms by Which Exogenous Substances Enhance Plant Salt Tolerance through the Modulation of Ion Membrane Transport and Reactive Oxygen Species Metabolism

Authors: Shiqing Jiang, Zuwen Lan, Yinkang Zhang, Xinna Kang, Liran Zhao, Xiaolei Wu, Hongbo Gao

Source: Antioxidants, Vol 13, Iss 9, p 1050 (2024)

Subject Terms: salt stress, exogenous substances, membrane transporters, ROS, plant hormones, signal transduction substances, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/9/1050; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/97c97b21becd4b9d87002d9a0d250255

Possible interactions between selected food processing and medications

Authors: Giuseppe Poli, Ettore Bologna, I. Sam Saguy

Source: Frontiers in Nutrition, Vol 11 (2024)

Subject Terms: food processing, thermal processing, non-thermal processing, food-drug interaction, membrane transporters, cytochrome P450, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2024.1380010/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/ae2ea44e22d14225ac65ec6b1c68a261

Sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xFAD mouse model of Alzheimer’s disease

Authors: Elena Puris, Liudmila Saveleva, Seppo Auriola, Mikko Gynther, Katja M. Kanninen, Gert Fricker

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: Alzheimer’s disease, membrane transporters, brain, 5XFAD mice, animal model, sex, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1365051/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/6b1f10f12cd449b08eba11fdd71da552

High-Throughput Expression and Purification of Human Solute Carriers for Structural and Biochemical Studies

Authors: Sagar Raturi, author¹, Huanyu Li, author¹, Yung-Ning Chang, author², Andreea Scacioc, author¹, Tina Bohstedt, author¹, Alejandra Fernandez-Cid, author¹, Adam Evans, author¹, Patrizia Abrusci, author¹, Abilasha Balakrishnan, author¹, Tomas C. Pascoa, author¹, Didi He, author¹, Gamma Chi, author¹, Nanki Kaur Singh, author¹, Mingda Ye, author¹, Anna Li, author¹, Leela Shrestha, author¹, Dong Wang, author¹, Eleanor P. Williams, author¹, Nicola A. Burgess-Brown, author¹, Katharina L. Dürr, author¹, Vera Puetter, author², Alvaro Ingles-Prieto, author³, David B. Sauer, author¹

Source: Journal of Visualized Experiments. (199)

Availability: http://www.jove.com/video/65878

Association between genetic variants of membrane transporters and the risk of high-grade hematologic adverse events in a cohort of Mexican children with B-cell acute lymphoblastic leukemia

Authors: Deyanira Escalante-Bautista, Doris Cerecedo, Elva Jiménez-Hernández, Carolina González-Torres, Javier Gaytán-Cervantes, Juan Carlos Núñez-Enríquez, Omar Alejandro Sepúlveda-Robles, Marlon De Ita, Silvia Jiménez-Morales, José Manuel Sánchez-López, Minerva Mata-Rocha, José Refugio Torres-Nava, Jorge Alfonso Martín-Trejo, Luz Victoria Flores-Villegas, María de Lourdes Gutiérrez-Rivera, Laura Elizabeth Merino-Pasaye, Karina Anastacia Solís-Labastida, María Raquel Miranda-Madrazo, Gabriela Alicia Hernández-Echáurregui, Darío Orozco-Ruíz, Janet Flores-Lujano, María Luisa Pérez-Saldívar, Juan Manuel Mejía-Aranguré, Haydeé Rosas-Vargas

Source: Frontiers in Oncology, Vol 13 (2024)

Subject Terms: pharmacogenomics, membrane transporters, toxicity, acute lymphoblastic leukemia, ATP-binding cassette transporter, solute carrier family, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1276352/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/65c3521f048247de93d211be7a5e6802

Editorial: Understanding membrane transporters: from structure to function

Authors: Andrea Pasquadibisceglie, Maria Carmela Bonaccorsi Di Patti, Daniela Valeria Miniero, Giovanni Musci, Fabio Polticelli

Source: Frontiers in Molecular Biosciences, Vol 10 (2023)

Subject Terms: membrane transporters, protein structure, protein function, molecular modeling, molecular dynamics, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1323824/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/feeb43744e2d44c18612347398c6e679

Inflammation and Organic Cation Transporters Novel (OCTNs)

Authors: Lorena Pochini, Michele Galluccio, Lara Console, Mariafrancesca Scalise, Ivano Eberini, Cesare Indiveri

Source: Biomolecules, Vol 14, Iss 4, p 392 (2024)

Subject Terms: membrane transporters, SLC, antioxidant, cation transporters, carnitine, acetylcholine, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/4/392; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/e599cf5177134ca3acc91aecbac10af1

Types of Membrane Transporters and the Mechanisms of Interaction between Them and Reactive Oxygen Species in Plants

Authors: Ding Yuan, Xiaolei Wu, Xiangqun Jiang, Binbin Gong, Hongbo Gao

Source: Antioxidants, Vol 13, Iss 2, p 221 (2024)

Subject Terms: membrane transporters, ROS, interaction mechanism, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/2/221; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/5da626b0435948bb95df16dbbdb27904

Cerebrospinal fluid production by the choroid plexus: a century of barrier research revisited

Authors: Nanna MacAulay, Richard F. Keep, Thomas Zeuthen

Source: Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-18 (2022)

Subject Terms: Cerebrospinal fluid, CSF, Choroid plexus, Blood-CSF-barrier, Osmotic gradients, Membrane transporters, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/6dcb57c57f894af5ba60d7b179b6044d

The effect of cinnamon (Cinnamomum zeylanicum) extract on modulating the expression of cation-chloride transporters (NKCC1 and KCC2) after stroke in rats receiving high-fat diet

Authors: Parvin Hojati, Mehdi Rahnema, Ali Rostami, Hossein Mostafavi

Source: Fiyz̤, Vol 26, Iss 5, Pp 491-500 (2022)

Subject Terms: strokes, cinnamon, membrane transporters, ischemia reperfusion injury, Medicine (General), R5-920

File Description: electronic resource

Relation: http://feyz.kaums.ac.ir/article-1-4707-en.html; https://doaj.org/toc/1029-7855; https://doaj.org/toc/2008-9821

Access URL: https://doaj.org/article/a84d16a348374aba8dc42f9651e15e52