Ezrin works as a scaffold protein for a macrophage checkpoint molecule CD47, leading to a poor prognosis for patients with uterine cervical squamous cell carcinoma

Authors: Takuro Kobori, Yui Ito, Yoko Urashima, Takuya Ito, Nobumasa Takagaki, Kikuko Hotta, Tokio Obata

Source: Taiwanese Journal of Obstetrics & Gynecology, Vol 64, Iss 2, Pp 239-247 (2025)

Subject Terms: Uterine cervical squamous cell carcinoma, Cancer immunotherapy, Macrophage checkpoint, CD47, Ezrin–radixin-moesin family member, Gynecology and obstetrics, RG1-991

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1028455925000208; https://doaj.org/toc/1028-4559

Access URL: https://doaj.org/article/4ade50ac70694b209a0a9dcf964b4abf

Preclinical evaluation of the efficacy of an antibody to human SIRPα for cancer immunotherapy in humanized mouse models

Authors: Yasuyuki Saito, Rie Iida-Norita, Tania Afroj, Alaa Refaat, Daisuke Hazama, Satomi Komori, Shinya Ohata, Tomoko Takai, Okechi S. Oduori, Takenori Kotani, Yohei Funakoshi, Yu-Ichiro Koma, Yoji Murata, Kimikazu Yakushijin, Hiroshi Matsuoka, Hironobu Minami, Hiroshi Yokozaki, Markus G. Manz, Takashi Matozaki

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: humanized mouse, tumor-associated macrophages, SIRP alpha, cancer immunotherapy, patient-derived xenograft (PDX) model, macrophage checkpoint, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1294814/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/784d3137dd2e455384e08104a9ce3615