Novel Antiviral Agents: Synthesis, Molecular Modelling Studies and Biological Investigation

Contributors: Brogi, Simone

Subject Terms: dialysis, end-stage kidney disease, hepatitis C virus, sofosbuvir, sustained viral response, carbapenem-resistant, Pseudomonas aeruginosa, bacteriophage, hydrogel, thermal injury model, histopathology, foot-and-mouth disease virus (FMDV), RNA-dependent RNA polymerase (RdRp), 3D polymerase (3Dpol), small molecule, virtual screening, antiviral cell-based assay, antiviral agent, PSP, HIV, proteomics, cofilin-1, PKR, IRE1α, UPR, Zika virus, peptide, antiviral, DV2 peptide, dengue virus, flavivirus, deep learning, SARS-CoV-2 Mpro, transfer learning, drug development, natural compound, virus, picornavirus, enterovirus, edible plant, PI4KB, influenza, neuraminidase inhibitors, noncompetitive inhibition, ligand docking, screening pitfalls, screening problems, HIV-1 gp120 V3 loop, chemokine receptor CXCR4, molecular recognition, D-peptide, HIV-1 entry, antiviral agents, coronaviruses, viral entry, antimicrobial, coronavirus, abietane, dehydroabietylamine, phenol, phthalimide, COVID-19, microscale thermophoresis, SLC6A20 amino acid transporter, Dengue virus, natural compounds, NS5 protein, antiviral activity, heterocycles, natural products, Structure Activity Relationship (SAR), synthetic methods, SARS-CoV-2, NSP3, macrodomain-I, medicinal compounds, computational biology, Medicine and Nursing

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/137483
https://mdpi.com/books/pdfview/book/8640

Targeting SARS-CoV-2 Macrodomain-1 to Restore the Innate Immune Response Using In Silico Screening of Medicinal Compounds and Free Energy Calculation Approaches

Authors: Anwar Mohammad, Eman Alshawaf, Hossein Arefanian, Sulaiman K. Marafie, Abbas Khan, Dong-Qing Wei, Fahd Al-Mulla, Jehad Abubaker

Source: Viruses, Vol 15, Iss 9, p 1907 (2023)

Subject Terms: SARS-CoV-2, NSP3, macrodomain-I, medicinal compounds, computational biology, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/9/1907; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/76bf277a9c774a0f9038c395c6c41ba0