Dysregulated lipid metabolism and intervertebral disc degeneration: the important role of ox-LDL/LOX-1 in endplate chondrocyte senescence and calcification

Authors: Tan Bing, Xiang Shanlin, Wang Jisheng, Hao Jie, Cao Ruichao, Zhang Zhiwei, Yu Bin, Ma Zhaoxin, Hu Zhenming, Zhou Nian

Source: Molecular Medicine, Vol 30, Iss 1, Pp 1-23 (2024)

Subject Terms: Intervertebral disc degeneration, Cell senescence and calcification, Lipid metabolism disorders, Oxidized low-density lipoprotein, Lectin-like oxidized low-density lipoprotein receptor 1, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/0c4632ac778b40c69048a85239072ef2

The Role of Natural Low Molecular Weight Dicarbonyls in Atherogenesis and Diabetogenesis

Authors: Vadim Z. Lankin, Alla K. Tikhaze, Mars G. Sharapov, Galina G. Konovalova

Source: Reviews in Cardiovascular Medicine, Vol 25, Iss 8, p 295 (2024)

Subject Terms: reactive oxygen species (ros), free radical oxidation (fro), superoxide anion radical (o2•-), lipoperoxides (looh), oxidative stress, low molecular weight dicarbonyls, malondialdehyde (mda), glyoxal, methylglyoxal, reactive carbonyl species (rcs), carbonyl stress, low density lipoproteins (ldl), oxidized (looh contained) ldl (looh-ldl), mda-modified ldl (mda-ldl), lectin like oxidized low density lipoprotein receptor 1 (lox-1), nadph oxidase 1 (nox-1), antioxidant enzymes, superoxide dismutase (sod), glutathione peroxidase (gsh-px), peroxiredoxines, endotheliocites, apoptosis, atherosclerosis, diabetes, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.imrpress.com/journal/RCM/25/8/10.31083/j.rcm2508295; https://doaj.org/toc/1530-6550

Access URL: https://doaj.org/article/844d8504a1e2472ca458692820769e09

Toll-like receptor 2 activation primes and upregulates osteoclastogenesis via lox-1

Authors: Kimiko Ohgi, Hiroshi Kajiya, Kazuko Goto-T, Fujio Okamoto, Yasunori Yoshinaga, Koji Okabe, Ryuji Sakagami

Source: Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-9 (2018)

Subject Terms: Dyslipidemia, Osteoclastogenesis, Toll-like receptor, Lectin-like oxidized low-density-lipoprotein receptor 1, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12944-018-0787-4; https://doaj.org/toc/1476-511X

Access URL: https://doaj.org/article/6ebd97ca2b7543728e04aefb55f1641b

Electronegative LDL circulating in smokers impairs endothelial progenitor cell differentiation by inhibiting Akt phosphorylation via LOX-1

Authors: Daming Tang, Jonathan Lu, Jeffrey P. Walterscheid, Hsin-Hung Chen, David A. Engler, Tatsuya Sawamura, Po-Yuan Chang, Hazim J. Safi, Chao-Yuh Yang, Chu-Huang Chen

Source: Journal of Lipid Research, Vol 49, Iss 1, Pp 33-47 (2008)

Subject Terms: electronegative low density lipoprotein, L5, lectin-like oxidized low density lipoprotein receptor 1, signal transduction, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520428780; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/b6a36432dbcd4385874d9023d4460f87

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