Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue

Authors: Masuda, Akari, Itai, Shun, Kurashina, Yuta, Tohyama, Shugo, Onoe, Hiroaki

Source: 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers) Solid-State Sensors, Actuators and Microsystems (Transducers), 2023 22nd International Conference on. :240-243 Jun, 2023

Relation: 2023 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers)

Therapeutic effects of lomerizine on vasculopathy in Fabry disease

Authors: Jong Bin Choi, Hyo-Sang Do, Dong-Won Seol, Hee-Young Yang, Taek-Min Kim, Youkyeong Gloria Byun, Jae-Min Park, Heounjeong Go, Jungjoo Park, Won-Suk Chung, Jae Myoung Suh, Beom Hee Lee, Gabbine Wee, Yong-Mahn Han

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-14 (2025)

Subject Terms: Fabry disease, iPSCs, Vascular endothelial cells, Drug screening, Lomerizine, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3475008085e749a395daab64dd908e52

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity

Authors: Mohammed R. Shaker, Salam Salloum-Asfar, Rowaida Z. Taha, Ibrahim Javed, Ernst J. Wolvetang

Source: Molecular Brain, Vol 18, Iss 1, Pp 1-7 (2025)

Subject Terms: Klotho, β-amyloid, Neurodegeneration, iPSCs, Cortical neurons, Alzheimer’s disease, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1756-6606

Access URL: https://doaj.org/article/0db4b002def94e4c987803426a3fd132

Inhibition of TGF-β signaling enhances osteogenic potential of iPSC-derived MSCs

Authors: Felix Umrath, Sarah-Lena Frick, Valerie Wendt, Andreas Naros, Rüdiger Zimmerer, Dorothea Alexander

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-15 (2025)

Subject Terms: Induced pluripotent stem cells (iPSCs), Mesenchymal stem cells (MSCs), iPSC-derived mesenchymal stem cells (iMSCs), SB431542, TGF-β inhibitor, Osteogenic differentiation, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/68bd7225b6e1466ab73ae4ce062cdda8

MAPT-A152T mutation drives neuronal hyperactivity through Fyn-NMDAR signaling in human iPSC-Derived neurons: Insights into Alzheimer's pathogenesis

Authors: Maika Itsuno, Hirokazu Tanabe, Etsuko Sano, Takashi Sasaki, Chisato Oyama, Hiroko Bannai, Koichi Saito, Kazuhiko Nakata, Setsu Endoh-Yamagami, Hideyuki Okano, Sumihiro Maeda

Source: Regenerative Therapy, Vol 28, Iss , Pp 201-213 (2025)

Subject Terms: Alzheimer's disease (AD), Induced pluripotent stem cells (iPSCs), hTau-A152T mutation, Tau-Fyn-NMDAR pathway, Medicine (General), R5-920, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352320424002281; https://doaj.org/toc/2352-3204

Access URL: https://doaj.org/article/57b7b8a562ec41e3a49f8118c86de3d9

Controlling Firing Point of Microfiber-Shaped Hipsc-Derived Cardiac Tissue with Localized Electrical Stimulation Device

Authors: Masuda, Akari, Itai, Shun, Kurashina, Yuta, Tohyama, Shugo, Onoe, Hiroaki

Source: 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS) Micro Electro Mechanical Systems (MEMS), 2023 IEEE 36th International Conference on. :305-308 Jan, 2023

Relation: 2023 IEEE 36th International Conference on Micro Electro Mechanical Systems (MEMS)

Development of iPSC-derived FIX-secreting hepatocyte sheet as a novel treatment tool for hemophilia B treatment

Authors: Delger Bayarsaikhan, Govigerel Bayarsaikhan, Jaesuk Lee, Teruo Okano, Kyungsook Kim, Bonghee Lee

Source: Stem Cell Research & Therapy, Vol 16, Iss 1, Pp 1-17 (2025)

Subject Terms: CRISPR/Cas9, FIX knock-in, Hepatocytes derived from iPSCs, APOC3, Cell sheet technology, Hepatocyte differentiation, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/c0fef109a69c4379ac40e5db6334b6dc

Development and evaluation of siRNA-mediated gene silencing strategies for ADO2 therapy utilizing iPSCs model and DMPC-SPIONs delivery system

Authors: Jiajun Xu, Gengshuo Chen, Chune Mo, Yu Sha, Sha Luo, Minglin Ou

Source: Stem Cell Research & Therapy, Vol 16, Iss 1, Pp 1-8 (2025)

Subject Terms: ADO2, iPSCs, siRNA, DMPC-SPIONs, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/e28bc61162504220ac8fe26a7321de49

Disruption of mitochondrial homeostasis and permeability transition pore opening in OPA1 iPSC-derived retinal ganglion cells

Authors: Michael Whitehead, Joshua P. Harvey, Paul E. Sladen, Giada Becchi, Kritarth Singh, Yujiao Jennifer Sun, Thomas Burgoyne, Michael R. Duchen, Patrick Yu-Wai-Man, Michael E. Cheetham

Source: Acta Neuropathologica Communications, Vol 13, Iss 1, Pp 1-13 (2025)

Subject Terms: Dominant optic atrophy, OPA1, iPSCs, Retinal ganglion cells, Neurodegeneration, Mitochondrial networks, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/e462392efec24fdda030d7dd6cbe6cb7

Constructing a potential HLA haplo-homozygous induced pluripotent stem cell haplobank using data from an umbilical cord blood bank

Authors: Ji He, Yanmin He, Qigang Zhan, Zhipan Wu, Qi Sheng, Wei Zhang, Faming Zhu

Source: Stem Cell Research & Therapy, Vol 16, Iss 1, Pp 1-10 (2025)

Subject Terms: iPSCs induced pluripotent stem cells, HLA homozygote, Haplobanking, Umbilical cord blood, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/391c76724e8c45ab8b19b56978fd9d6c

TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes

Authors: Wenrui Sun, Jianchao Zhang, Shuang Li, Wanrong Fu, Yangyang Liu, Mengduan Liu, Jianzeng Dong, Xiaoyan Zhao, Xiaowei Li

Source: Molecular Medicine, Vol 31, Iss 1, Pp 1-17 (2025)

Subject Terms: TAB2 knockout, IPSCs, Dilated cardiomyopathy, Mitochondrial calcium overload, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/5d351cdb74c74a318e28c7aece5238ca

Combining Off‐flow, a Nextflow‐coded program, and whole genome sequencing reveals unintended genetic variation in CRISPR/Cas-edited iPSCs

Authors: Carole Shum, Sang Yeon Han, Bhooma Thiruvahindrapuram, Zhuozhi Wang, Jill de Rijke, Benjamin Zhang, Maria Sundberg, Cidi Chen, Elizabeth D. Buttermore, Nina Makhortova, Jennifer Howe, Mustafa Sahin, Stephen W. Scherer

Source: Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 638-647 (2024)

Subject Terms: Induced pluripotent stem cells (iPSCs), Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), Genome editing, Whole genome sequencing (WGS), Off-target detection, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S200103702300510X; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/fce05ccaaede435b84e6e74474bfe7f5

SLC26A4 C.317C > A Variant: Functional Analysis and Patient‐Derived Induced Pluripotent Stem Line Development

Authors: Yijing Li, Tao Sun, Sang Hu, Hongen Xu, Teng Zhang, Jinlong Liu, Shuangshuang Lu, Bing Wang, Guo Dan

Source: Molecular Genetics & Genomic Medicine, Vol 13, Iss 4, Pp n/a-n/a (2025)

Subject Terms: c.317C > a, hearing loss, iPSCs, SLC26A4, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2324-9269

Access URL: https://doaj.org/article/826c4f1ae9a34e4d86d5cee695c641c1

Advances in cell therapy for orthopedic diseases: bridging immune modulation and regeneration

Authors: Jing Wang, Shenghao Xu, Bo Chen, Yanguo Qin

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: cell therapy, orthopedic diseases, immunotherapy, MSCs, iPSCs, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1567640/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ee8ec5ef1b594b3fa005f9bef6c0157b

Fixation-Free Evaluation of Cardiac Contractile Force by Human iPSC-Derived Cardiac Core-Shell Microfiber

Authors: Masuda, Akari, Fukada, Keisuke, Itai, Shun, Kurashina, Yuta, Akizuki, Shuichi, Tohyama, Shugo, Fujita, Jun, Onoe, Hiroaki

Source: 2022 IEEE 35th International Conference on Micro Electro Mechanical Systems Conference (MEMS) Micro Electro Mechanical Systems Conference (MEMS), 2022 IEEE 35th International Conference on. :172-175 Jan, 2022

Relation: 2022 IEEE 35th International Conference on Micro Electro Mechanical Systems Conference (MEMS)

Classification of iPSC-derived cultures using convolutional neural networks to identify single differentiated neurons for isolation or measurement

Authors: Purva Patel, Lina K. Mohammed Ali, Uma Kaushik, Mallory Wright, Kaylee Green, Jason E. Waligorski, Colin L. Kremitzki, Graham W. Bachman, Serena N. Elia, William J. Buchser

Source: Discover Artificial Intelligence, Vol 4, Iss 1, Pp 1-14 (2024)

Subject Terms: iPSCs, Neurons, Machine learning, CNN, Microrafts, Image classification, Computational linguistics. Natural language processing, P98-98.5, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: https://doaj.org/toc/2731-0809

Access URL: https://doaj.org/article/2c929821b2f543e883e00ea1a17ed567

Prolonged cultivation enhances the stimulatory activity of hiPSC mesenchymal progenitor-derived conditioned medium

Authors: Darja Marolt Presen, Vanessa Goeschl, Dominik Hanetseder, Laura Ogrin, Alexandra-Larissa Stetco, Anja Tansek, Laura Pozenel, Bella Bruszel, Goran Mitulovic, Johannes Oesterreicher, Johannes Zipperle, Barbara Schaedl, Wolfgang Holnthoner, Johannes Grillari, Heinz Redl

Source: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-22 (2024)

Subject Terms: Conditioned medium, Secretome, Human iPSCs, Human bone marrow mesenchymal stromal cells, Mesenchymal progenitors, Osteogenic differentiation, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/5f30f58b46244a1a9d29c678452bb930

Saxitoxin potentiates human neuronal cell death induced by Zika virus while sparing neural progenitors and astrocytes

Authors: Leticia R. Q. Souza, Carolina G. da S. Pedrosa, Teresa Puig-Pijuan, Camila da Silva dos Santos, Gabriela Vitória, João M. A. Delou, Pedro Setti-Perdigão, Luiza M. Higa, Amilcar Tanuri, Stevens Kastrup Rehen, Marília Zaluar P. Guimarães

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Subject Terms: Zika Virus (Zikv), Saxitoxin (STX), Congenital Zika Syndrome (SCZ), Induced pluripotent stem cells (IPSCS), Neurons, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/d8dcaae1fcbd48feb4760630394c60cb

Enhanced spinal cord repair using bioengineered induced pluripotent stem cell-derived exosomes loaded with miRNA

Authors: Azar Abbas, Xiaosheng Huang, Aftab Ullah, Lishi Luo, Wenqun Xi, Yuanjiao Qiao, Kun Zeng

Source: Molecular Medicine, Vol 30, Iss 1, Pp 1-12 (2024)

Subject Terms: Spinal cord injury (SCI), Induced pluripotent stem cells-derived exosomes (iPSCs-Exo), miR-23b, miR-21-5p, miR-199b-5p, Etc, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/d08e93e591ed4292b07a290ddc8625ad

Optical genome mapping of structural variants in Parkinson’s disease-related induced pluripotent stem cells

Authors: Joanne Trinh, Susen Schaake, Carolin Gabbert, Theresa Lüth, Sally A. Cowley, André Fienemann, Kristian K. Ullrich, Christine Klein, Philip Seibler

Source: BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)

Subject Terms: Optical genome mapping, iPSCs, Parkinson’s disease, Structural variants, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/cef0b56f4f56419a8a23798df35cef52