A novel truncated variant in SPAST results in spastin accumulation and defects in microtubule dynamics

Authors: Jie Wang, Yihan Wu, Hong Dong, Yunpeng Ji, Lichun Zhang, Yaxian Liu, Yueshi Liu, Xin Gao, Yueqi Jia, Xiaohua Wang

Source: BMC Medical Genomics, Vol 16, Iss 1, Pp 1-9 (2023)

Subject Terms: SPAST, Hereditary spastic paraplegias, Spastin, Intracellular accumulation, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/9e1740a5dff44831af5edc7ef8df83e4

Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells

Authors: Kupryushkin, Maxim S. ^{1, 7}, Filatov, Anton V. ^{1, 7}, Mironova, Nadezhda L. ^{1, ∗}, Patutina, Olga A. ¹, Chernikov, Ivan V. ¹, Chernolovskaya, Elena L. ¹, Zenkova, Marina A. ¹, Pyshnyi, Dmitrii V. ¹, Stetsenko, Dmitry A. ^{2, 3}, Altman, Sidney ^{4, 5, 6, ∗∗}, Vlassov, Valentin V. ¹

Source: In Molecular Therapy - Nucleic Acids 8 March 2022 27:211-226

Microbubble-Assisted Ultrasound for Drug Delivery to the Retina in an Ex Vivo Eye Model

Authors: Charis Rousou, Nicky van Kronenburg, Andreas F. P. Sonnen, Marijke van Dijk, Chrit Moonen, Gert Storm, Enrico Mastrobattista, Roel Deckers

Source: Pharmaceutics, Vol 15, Iss 4, p 1220 (2023)

Subject Terms: ultrasound, microbubbles, intracellular accumulation, ex vivo perfused eye, retinal drug delivery, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/4/1220; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/4c3e25033dd34dc18301425251e35cd8

Intracellular Accumulation of Novel and Clinically Used TB Drugs Potentiates Intracellular Synergy

Authors: Lloyd Tanner, Gabriel T. Mashabela, Charles C. Omollo, Timothy J. de Wet, Christopher J. Parkinson, Digby F. Warner, Richard K. Haynes, Lubbe Wiesner

Source: Microbiology Spectrum, Vol 9, Iss 2 (2021)

Subject Terms: TB chemotherapy, intracellular accumulation, macrophages, intracellular efficacy, phenoxazine, artemisinin, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/55ee631add7144e2a9c75f600d8c779b

Synthesis of Cobalt Bis(Dicarbollide)—Curcumin Conjugates for Potential Use in Boron Neutron Capture Therapy

Authors: Lyubov G. Dezhenkova, Anna A. Druzina, Yulia L. Volodina, Nadezhda V. Dudarova, Natalia A. Nekrasova, Olga B. Zhidkova, Mikhail A. Grin, Vladimir I. Bregadze

Source: Molecules, Vol 27, Iss 14, p 4658 (2022)

Subject Terms: curcumin, cobalt bis(dicarbollide), polyhedral boron compounds, cell viability, intracellular accumulation, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/14/4658; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/c61d34e92a1940008678e5e0d3240630

The Effect of Microbubble-Assisted Ultrasound on Molecular Permeability across Cell Barriers

Authors: Charis Rousou, Josanne de Maar, Boning Qiu, Kim van der Wurff-Jacobs, Marika Ruponen, Arto Urtti, Sabrina Oliveira, Chrit Moonen, Gert Storm, Enrico Mastrobattista, Roel Deckers

Source: Pharmaceutics, Vol 14, Iss 3, p 494 (2022)

Subject Terms: ultrasound, microbubbles, epithelial permeation, paracellular permeability, intracellular accumulation, nanobody, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/3/494; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/617e21bbdeb14c44b399418198e81166

Spreading of amyloid-β peptides via neuritic cell-to-cell transfer is dependent on insufficient cellular clearance

Authors: Jakob Domert, Sahana Bhima Rao, Lotta Agholme, Ann-Christin Brorsson, Jan Marcusson, Martin Hallbeck, Sangeeta Nath

Source: Neurobiology of Disease, Vol 65, Iss , Pp 82-92 (2014)

Subject Terms: Alzheimer's disease, Amyloid-β oligomers, Cell-to-cell transfer, Prion-like propagation, Intracellular accumulation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996114000060; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/96c2d315cfd949618e393a8c2edc1f4e

Intracellular Accumulation as an Indicator of Cytotoxicity to Screen Hepatotoxic Components of Chelidonium majus L. by LC–MS/MS

Authors: Cuiting Wu, Xin Wang, Ming Xu, Youping Liu, Xin Di

Source: Molecules, Vol 24, Iss 13, p 2410 (2019)

Subject Terms: intracellular accumulation, LC–MS/MS, alkaloids, hepatotoxicity, Chelidonium majus L., cytotoxicity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/13/2410; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/82f6a5e2d2c24bc8a280d9c92bbdaeea

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