Percutaneous pedicle screw fixation in the surgical treatment of monosegmental pyogenic spondylodiscitis.

Authors: Chen, Zhen-Zhong^1,2, Zhu, Ke-Jun³, Pan, Bin³, Lou, Chao^1,2, Yu, Wei-Yang^1,2, He, Deng-Wei^1,2 hedw_spine@163.com

Source: Journal of Orthopaedic Surgery & Research. 3/6/2025, Vol. 20 Issue 1, p1-9. 9p.

Subject Terms: *INFLAMMATORY mediators, *RESEARCH funding, *BONE screws, *FRACTURE fixation, *VISUAL analog scale, *QUESTIONNAIRES, *EPIDURAL abscess, *TREATMENT effectiveness, *SURGICAL blood loss, *SURGICAL complications, *SPINAL fusion, *DISCITIS, *SURGICAL instruments, *DEBRIDEMENT, *SPINE diseases, *JOINT instability, *EVALUATION, *DISEASE risk factors

Scopolamine-induced memory impairment in mice: Soursop leaf extract and fractions protect the hippocampus and prefrontal cortex.

Authors: Afolabi, Faith¹, Alabi, Babatunde Adebola^2,3 adebolalabi@gmail.com, Badejo, Joseph Ayo¹, Nsor, Okim Okim¹, Lawal, Sodiq Kolawole⁴, Iwalewa, Ezekiel Olugbenga¹

Source: Iranian Journal of Basic Medical Sciences. Mar2025, Vol. 28 Issue 3, p355-365. 11p.

Subject Terms: *GLUTAMATE decarboxylase, *INFLAMMATORY mediators, *ORNAMENTAL plants, *MEMORY disorders, *GLUTAMIC acid

Time-sensitive effects of quercetin on rat basophilic leukemia (RBL-2H3) cell responsiveness and intracellular signaling.

Authors: Matsuo, Mana¹ (AUTHOR), Liu, Shuang¹ (AUTHOR) liussmzk@m.ehime-u.ac.jp, Yamada, Haruna¹ (AUTHOR), Takemasa, Erika¹ (AUTHOR), Suzuki, Yasuyuki^1,2,3 (AUTHOR), Mogi, Masaki¹ (AUTHOR)

Source: PLoS ONE. 2/24/2025, Vol. 20 Issue 2, p1-16. 16p.

Subject Terms: *MAST cells, *INFLAMMATORY mediators, *QUERCETIN, *GHRELIN receptors, *CELLULAR signal transduction

Polymorphic Variants of Peptidylarginine Deiminase Gene from P. gingivalis —Searching for Targets for Supportive Therapy of Periodontitis.

Authors: Strzelec, Karolina¹ (AUTHOR), Dziedzic-Kowalska, Agata^1,2 (AUTHOR), Sieron, Łukasz^2,3 (AUTHOR), Bereta, Grzegorz P.^3,4 (AUTHOR), Stepien, Karolina L.^1,5 (AUTHOR), Ferenc, Klara^1,6 (AUTHOR), Łazarz-Bartyzel, Katarzyna^1,4 (AUTHOR), Olszewska-Czyż, Iwona^2,4 (AUTHOR), Rąpalska, Iwona^3,5 (AUTHOR), Aptekorz, Małgorzata^4,6 (AUTHOR), Kaczmarzyk, Tomasz⁵ (AUTHOR), Cześnikiewicz-Guzik, Marta^4,6 (AUTHOR), Gawron, Katarzyna¹ (AUTHOR) kgawron@sum.edu.pl

Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 4, p1662. 23p.

Subject Terms: *MISSENSE mutation, *INFLAMMATORY mediators, *GENETIC variation, *ORAL diseases, *PERIODONTITIS

Increased plasma lipopolysaccharide-binding protein and altered inflammatory mediators reveal a pro-inflammatory state in overweight women.

Authors: Metz, Christine N.^1,2 (AUTHOR) cmetz@northwell.edu, Brines, Michael¹ (AUTHOR), Xue, Xiangying¹ (AUTHOR), Chatterjee, Prodyot K.¹ (AUTHOR), Adelson, Robert P.¹ (AUTHOR), Roth, Jesse^1,2 (AUTHOR), Tracey, Kevin J.^1,2 (AUTHOR), Gregersen, Peter K.^1,2 (AUTHOR), Pavlov, Valentin A.^1,2 (AUTHOR) vpavlov@northwell.edu

Source: BMC Women's Health. 2/10/2025, Vol. 25 Issue 1, p1-8. 8p.

Subject Terms: *INFLAMMATORY mediators, *BLOOD proteins, *HYPERTENSION, *INFLAMMATION, *LEPTIN

The Anti-Inflammatory Potential of Tricyclic Antidepressants (TCAs): A Novel Therapeutic Approach to Atherosclerosis Pathophysiology.

Authors: Eslami, Majid¹ (AUTHOR) m.eslami@semums.ac.ir, Monemi, Marzieh² (AUTHOR), Nazari, Mohammad Ali³ (AUTHOR), Azami, Mohammad Hossein³ (AUTHOR), Shariat Rad, Parand⁴ (AUTHOR), Oksenych, Valentyn⁵ (AUTHOR) valentyn.oksenych@uib.no, Naderian, Ramtin⁶ (AUTHOR) ramtinndn@gmail.com

Source: Pharmaceuticals (14248247). Feb2025, Vol. 18 Issue 2, p197. 27p.

Subject Terms: *PYRIN (Protein), *INFLAMMATORY mediators, *TRICYCLIC antidepressants, *CARDIOVASCULAR diseases risk factors, *MENTAL depression

The Potential Roles of IL-1β, IL-6, and RIPK3 in the Pathogenesis of Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis.

Authors: Sooranahalli, Chandana¹ (AUTHOR) csooranahalli@luc.edu, Rao, Vidhya R.² (AUTHOR) vrao2@luc.edu, Zelman, Brandon³ (AUTHOR) brandon.zelman@luhs.org, Shekhar, Mallika¹ (AUTHOR) mshekhar@luc.edu, Komurlu Keceli, Sevnur⁴ (AUTHOR) skomurlu@luc.edu, Bouchard, Charles² (AUTHOR) cboucha@lumc.edu, Iqbal, Omer⁵ (AUTHOR) oiqbal@luc.edu

Source: Diagnostics (2075-4418). Feb2025, Vol. 15 Issue 3, p290. 13p.

Subject Terms: *TOXIC epidermal necrolysis, *INFLAMMATORY mediators, *LICHEN planus, *SKIN biopsy, *INTERLEUKIN-6

Advances in the Regulation of Inflammatory Mediators in Nitric Oxide Synthase: Implications for Disease Modulation and Therapeutic Approaches.

Authors: Kim, Mi Eun¹ (AUTHOR) kimme0303@chosun.ac.kr, Lee, Jun Sik¹ (AUTHOR) junsiklee@chosun.ac.kr

Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 3, p1204. 19p.

Subject Terms: *INFLAMMATORY mediators, *CELL communication, *CELLULAR signal transduction, *CARDIOVASCULAR diseases, *HOMEOSTASIS, *NITRIC-oxide synthases

Nobiletin and Eriodictyol Suppress Release of IL-1β, CXCL8, IL-6, and MMP-9 from LPS, SARS-CoV-2 Spike Protein, and Ochratoxin A-Stimulated Human Microglia.

Authors: Tsilioni, Irene¹ (AUTHOR), Kempuraj, Duraisamy² (AUTHOR), Theoharides, Theoharis C.^1,2 (AUTHOR) ttheohar@nova.edu

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p636. 11p.

Subject Terms: *SARS-CoV-2, *INFLAMMATORY mediators, *POST-acute COVID-19 syndrome, *ENZYME-linked immunosorbent assay, *MAST cells, *OCHRATOXINS

Effects of the pan-caspase inhibitor Q-VD-OPh on human neutrophil lifespan and function.

Authors: Khuu, Lisa¹ (AUTHOR), Pillay, Alisha¹ (AUTHOR), Prichard, Allan^1,2 (AUTHOR), Allen, Lee-Ann H.^1,2 (AUTHOR) lee-ann.allen@health.missouri.edu

Source: PLoS ONE. 1/7/2025, Vol. 19 Issue 1, p1-24. 24p.

Subject Terms: *MYELOID cells, *INFLAMMATORY mediators, *NADPH oxidase, *CELL separation, *GROWTH factors

Gedunin Mitigates Cutibacterium acnes -Induced Skin Inflammation by Inhibiting the NF-κB Pathway.

Authors: Sim, Ju Kyoung¹ (AUTHOR) tla0156@kangwon.ac.kr, Heo, Ye Ji¹ (AUTHOR) hyj001001@kangwon.ac.kr, Shin, Jin Hak¹ (AUTHOR) wlsgkr1876@kangwon.ac.kr, Kim, Seon Sook² (AUTHOR) painniche@kangwon.ac.kr, Seo, Su Ryeon^1,3 (AUTHOR) suryeonseo@kangwon.ac.kr

Source: Pharmaceuticals (14248247). Jan2025, Vol. 18 Issue 1, p71. 15p.

Subject Terms: *INFLAMMATORY mediators, *CUTIBACTERIUM acnes, *NITRIC-oxide synthases, *NF-kappa B, *MITOGEN-activated protein kinases

Agathisflavone Inhibits Viability and Modulates the Expression of miR-125b, miR-155, IL-6, and Arginase in Glioblastoma Cells and Microglia/Macrophage Activation.

Authors: da Silva, Karina Costa¹ (AUTHOR) enf.karinac@gmail.com, Lima, Irlã Santos¹ (AUTHOR) irlalima@ufba.br, Santos, Cleonice Creusa dos¹ (AUTHOR) cleonicemev@gmail.com, Nonaka, Carolina Kymie Vasques² (AUTHOR) carolina.nonaka@hsr.com.br, Souza, Bruno Solano de Freitas^2,3 (AUTHOR) bruno.solano@idor.org.br, David, Jorge Mauricio⁴ (AUTHOR) jmdavid@ufba.br, Ulrich, Henning⁵ (AUTHOR) henning@iq.usp.br, Nascimento, Ravena Pereira do¹ (AUTHOR) ravenanascimento@ufba.br, Costa, Maria de Fátima Dias^1,6 (AUTHOR) fatima@ufba.br, dos Santos, Balbino Lino^1,7 (AUTHOR) balbino.lino@univasf.edu.br, Costa, Silvia Lima^1,6 (AUTHOR) balbino.lino@univasf.edu.br

Source: Molecules. Jan2025, Vol. 30 Issue 1, p158. 15p.

Subject Terms: *INFLAMMATORY mediators, *GENE expression, *CELL migration, *MACROPHAGE activation, *MICROGLIA

Association of The MCP-1 rs1024611 Polymorphism with Polycystic Ovary Syndrome in A Population of Indian Women: A Case-Control Study.

Authors: Francis, Jijo^1,2, Sebastian, Honey³, Daniel, Saley⁴, Varghese, Leyon¹, Gilvaz, Sareena⁴, Sankarankutty, Ragitha Thenkattil², George, Siji Susan⁵, Varghese, Pulikkottil Raphael², Raveendran, Suresh Kumar² drsureshkumar@jmmc.ac.in

Source: International Journal of Fertility & Sterility. Jan-Mar2025, Vol. 19 Issue 1, p44-49. 6p.

Subject Terms: *INFLAMMATORY mediators, *POLYMERASE chain reaction, *POLYCYSTIC ovary syndrome, *GENETIC polymorphisms, *GENETIC variation, *CASE-control method, *WOMEN'S health, *GENOTYPES, *ALLELES

Geographic Terms: INDIA

In Silico Study of Neoagaro-Oligosaccharides (NAOS) Anti- Inflammatory Activity: Molecular Docking with iNOS and COX-2 Proteins.

Authors: Puspitasari, Pinki Anggrahini¹ pinkianggrahinipuspitasari@mail.ugm.ac.id, Pratitis, Visi Endah¹ visiendahpratitis@mail.ugm.ac.id, Wibowo, Syahputra^1,2 syahputra.wibowo@brin.go.id, Wijayanti, Nastiti¹ nastiti_wijayanti@ugm.ac.id, Sofyantoro, Fajar¹ fajar.sofyantoro@ugm.ac.id

Source: Pertanika Journal of Tropical Agricultural Science. Jan2025, Vol. 48 Issue 1, p279-293. 15p.

Subject Terms: *INFLAMMATORY mediators, *DEGREE of polymerization, *MOLECULAR docking, *CYCLOOXYGENASE 2, *LIGANDS (Biochemistry), *PROTEIN-ligand interactions

Bacterial endotoxin-lipopolysaccharide role in inflammatory diseases: An overview.

Authors: Arya, Priyanka¹, Sharma, Vikram¹, Singh, Priyanka², Thapliyal, Surabhi³, Sharma, Manu²

Source: Iranian Journal of Basic Medical Sciences. May2025, Vol. 28 Issue 5, p553-564. 12p.

Subject Terms: *INFLAMMATORY mediators, *ALZHEIMER'S disease, *SEPTIC shock, *INFLAMMATION, *TOLL-like receptors

Ameliorative effect of morin on diclofenac-induced testicular toxicity in rats: An investigation into different signal pathways.

Authors: Şimşek, Hasan¹ hasansimsek@aksaray.edu.tr, Akaras, Nurhan², Gür, Cihan³, Küçükler, Sefa⁴, İleritürk, Mustafa⁵, Kandemir, Fatih Mehmet⁶

Source: Iranian Journal of Basic Medical Sciences. Apr2025, Vol. 28 Issue 4, p507-515. 9p.

Subject Terms: *INFLAMMATORY mediators, *ENDOPLASMIC reticulum, *FLAVONOIDS, *OXIDATIVE stress, *HUMAN body

Cannabichromene as a Novel Inhibitor of Th2 Cytokine and JAK/STAT Pathway Activation in Atopic Dermatitis Models.

Authors: Kim, Ki Chan¹ (AUTHOR) kimkichan01@naver.com, Jeong, Ga Hee¹ (AUTHOR) worldgh27@naver.com, Bang, Chul Hwan^1,2 (AUTHOR) mrbangga@catholic.ac.kr, Lee, Ji Hyun^1,2 (AUTHOR) ejee@catholic.ac.kr

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13539. 13p.

Subject Terms: *REVERSE transcriptase polymerase chain reaction, *INFLAMMATORY mediators, *TRP channels, *CANNABIDIOL, *WESTERN immunoblotting, *ATOPIC dermatitis, *GENE expression

Exploring the Link Between Psoriasis and Adipose Tissue: One Amplifies the Other.

Authors: Di Caprio, Roberta¹ (AUTHOR) rob.dicaprio@gmail.com, Nigro, Ersilia^2,3 (AUTHOR), Di Brizzi, Eugenia Veronica¹ (AUTHOR), Buononato, Dario¹ (AUTHOR), Mallardo, Marta^3,4 (AUTHOR), Tancredi, Vittorio¹ (AUTHOR), Daniele, Aurora^3,4 (AUTHOR), Balato, Anna¹ (AUTHOR) rob.dicaprio@gmail.com

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13435. 11p.

Subject Terms: *SKIN inflammation, *INFLAMMATORY mediators, *ORGAN culture, *INFLAMMATION, *INTERLEUKIN-17, *ADIPOKINES

Exploration and breakthrough in the mode of intervertebral disc cell death may lead to significant advances in treatments for intervertebral disc degeneration.

Authors: Chen, Heng^1,2, Tang, Tian¹, Xue, Congyang^1,2, Liu, Xin^1,2, Xi, Zhipeng¹, Xie, Lin^1,3 xielin@njucm.edu.cn, Kang, Ran^1,3 kangran126@126.com

Source: Journal of Orthopaedic Surgery & Research. 12/5/2024, Vol. 19 Issue 1, p1-15. 15p.

Subject Terms: *CELL transplantation, *INFLAMMATORY mediators, *APOPTOSIS, *CELLULAR aging, *CELL physiology, *EPIGENOMICS, *CELLULAR signal transduction, *INTERVERTEBRAL disk, *CELL death, *PHYSIOLOGIC strain, *MOLECULAR biology, *SPINE diseases, *DISEASE progression, *LUMBAR pain

Nerelimomab Alleviates Capsaicin-Induced Acute Lung Injury by Inhibiting TNF Signaling and Apoptosis.

Authors: Huang, Lijuan^1,2 (AUTHOR) huanglijuanlmm@sina.com, Du, Bing² (AUTHOR), Cui, Xiaohu² (AUTHOR), Zhao, Hanqing² (AUTHOR), Feng, Yanlin² (AUTHOR), Xu, Ziying² (AUTHOR), Long, Jianhai³ (AUTHOR), Yuan, Jing² (AUTHOR) yuanjing6216@163.com, You, Fuping¹ (AUTHOR) yuanjing6216@163.com

Source: Pharmaceuticals (14248247). Dec2024, Vol. 17 Issue 12, p1694. 17p.

Subject Terms: *LUNG injuries, *INFLAMMATORY mediators, *EPITHELIAL cells, *PATHOLOGICAL physiology, *CELL analysis, *LUNGS