Modified mesenchymal stromal cells by in vitro transcribed mRNA: a therapeutic strategy for hepatocellular carcinoma

Authors: María José Cantero, Barbara Bueloni, Lucrecia Gonzalez Llamazares, Esteban Fiore, Lucia Lameroli, Catalina Atorrasagasti, Guillermo Mazzolini, Mariana Malvicini, Juan Bayo, Mariana G. García

Source: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)

Subject Terms: Mesenchymal stromal cell, Granulocyte-macrophage colony-stimulating factor, In vitro transcribed mRNA, Immunogenic cell death, Immunotherapy, Hepatocellular carcinoma, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/b013aa8bb06f46989471717cdc2d7aa1

mRNA PROTACs: engineering PROTACs for high‐efficiency targeted protein degradation

Authors: Xiaoqi Xue, Chen Zhang, Xiaolin Li, Junqiao Wang, Haowei Zhang, Ying Feng, Naihan Xu, Hongyan Li, Chunyan Tan, Yuyang Jiang, Ying Tan

Source: MedComm, Vol 5, Iss 2, Pp n/a-n/a (2024)

Subject Terms: in vitro transcribed mRNA (IVT‐mRNA), mRNA, peptide proteolysis‐argeting chimeras, proteolysis‐argeting chimeras (PROTAC), Targeted protein degradation (TPD), Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/740a31d92bb346b099efe772c93b2261

Lateral flow immunoassay for rapid and sensitive detection of dsRNA contaminants in in vitro-transcribed mRNA products

Authors: Dengwang Luo, Zhanfeng Wu, Daming Wang, Jieli Zhang, Fei Shao, Shuo Wang, Stefano Cestellos-Blanco, Dawei Xu, Yuhong Cao

Source: Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 445-453 (2023)

Subject Terms: MT: Oligonucleotides: Diagnostics and Biosensors, In vitro-transcribed mRNA, double-stranded RNA, lateral flow strip assay, rapid and sensitive detection, dot-blot assay, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253123000914; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/16bebe1cdeee40ed8822234e5ca15d26

Advances in DNA Vaccines

Contributors: Isaguliants, Maria, Ljungberg, Karl

Subject Terms: alphaviruses, layered RNA/DNA vectors, DNA vaccines, RNA replicons, recombinant particles, tumor regression, protection against tumor challenges and infectious agents, ebola virus disease, artificial T-cell antigens, DNA vaccine constructs, computer design, gene expression, immunogenicity, DNA vaccine, mRNA vaccine, plasmid DNA, in vitro transcribed mRNA, immune responses, formulations, Cytolytic T Lymphocytes, antibodies, innate immunity, adjuvants, vaccine delivery, plasmid, cytolytic, perforin, bicistronic, HCV, HIV, IL-36, adjuvant, DNA, Zika, Epstein-Barr virus, latent proteins, LMP2, EBNA1, LMP1, HIV-1, enhancer element, circovirus, influenza, immunization, intranasal, lipid, flagellin, BCG, vaccine, rBCG, HTI, T-cell, AIDS, clinical trial, therapeutic vaccine, hepatitis C virus (HCV), mesenchymal stem cells (MSC), modified MSC, DNA immunization, nonstructural HCV proteins, immune response, HCV vaccine, myeloid derived suppressor cells (MDSCs), Medicine and Nursing, Epidemiology and Medical statistics

File Description: image/jpeg

Access URL: https://directory.doabooks.org/handle/20.500.12854/76819
https://mdpi.com/books/pdfview/book/4268

Protein Transduction Domain-Mediated Delivery of Recombinant Proteins and In Vitro Transcribed mRNAs for Protein Replacement Therapy of Human Severe Genetic Mitochondrial Disorders: The Case of Sco2 Deficiency

Authors: Androulla N. Miliotou, Parthena F. Foltopoulou, Alexandra Ingendoh-Tsakmakidis, Asterios S. Tsiftsoglou, Ioannis S. Vizirianakis, Ioannis S. Pappas, Lefkothea C. Papadopoulou

Source: Pharmaceutics, Vol 15, Iss 1, p 286 (2023)

Subject Terms: protein replacement therapy, mitochondrial disorders, protein transduction domain technology, recombinant proteins, in vitro transcribed mRNA (IVT-mRNA), Sco2, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/1/286; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/9409a121f06649b0b969862185ffe7b2

Design of in vitro Transcribed mRNA Vectors for Research and Therapy

Authors: Marina Tusup, Lars E. French, Mara De Matos, David Gatfield, Thomas Kundig, Steve Pascolo

Source: CHIMIA, Vol 73, Iss 5 (2019)

Subject Terms: Cap, Gene therapy, Globin utr, In vitro transcribed mrna, Ivt rna, Vaccination, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/1249; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

Access URL: https://doaj.org/article/a09f881ec4c8407db4012e9113d7d935

mRNA-Based Anti-TCR CDR3 Tumour Vaccine for T-Cell Lymphoma

Authors: Marina Tusup, Severin Läuchli, Natalia Teresa Jarzebska, Lars E. French, Yun-Tsan Chang, Maya Vonow-Eisenring, Andreas Su, Thomas M. Kündig, Emmanuella Guenova, Steve Pascolo

Source: Pharmaceutics, Vol 13, Iss 7, p 1040 (2021)

Subject Terms: in vitro transcribed mRNA, ivt mRNA, vaccine, T-cell lymphoma, CTCL, TCR, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/7/1040; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/740ac46bbfb44586b93eb42bb91c79c1

Neoantigen Vaccine Delivery for Personalized Anticancer Immunotherapy

Authors: Yugang Guo, Kewen Lei, Li Tang

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: neoantigen, cancer vaccine, cancer immunotherapy, vaccine delivery, in vitro transcribed mRNA, synthetic long peptide, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01499/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/49086caec0ab4d36a403004cc3fd6480

A Comparison of Plasmid DNA and mRNA as Vaccine Technologies

Authors: Margaret A. Liu

Source: Vaccines, Vol 7, Iss 2, p 37 (2019)

Subject Terms: DNA vaccine, mRNA vaccine, plasmid DNA, in vitro transcribed mRNA, immune responses, formulations, Cytolytic T Lymphocytes, antibodies, innate immunity, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/7/2/37; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/7f70c8bf80cc4a01882db0944cf1d4a9

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