Mechanism of histone demethylase KDM5A in osteoporotic fracture healing through epigenetic regulation of the miR-495/SKP2/Runx2 axis

Authors: Zhuoran Li, Junyan Zhang, Tingting Xu, Zhiying Hao, Yadong Li

Source: Molecular Medicine, Vol 31, Iss 1, Pp 1-17 (2025)

Subject Terms: Fracture healing, Histone demethylase, KDM5A, Epigenetics, miR-495, SKP2, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

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LSD1 is a targetable vulnerability in gastric cancer harboring TP53 frameshift mutations

Authors: Suzeng Wang, Chunyu Yang, Junhui Tang, Kaiqing Wang, Hao Cheng, Surui Yao, Zhaohui Huang, Bojian Fei

Source: Clinical Epigenetics, Vol 17, Iss 1, Pp 1-14 (2025)

Subject Terms: Gastric cancer, Histone demethylase, TP53, LSD1, Frameshift mutations, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/67a4e9862bf5487296e17df1d8424f41

The Histone Lysine Demethylase KDM7A Contributes to Reward Memory via Fscn1‐Induced Synaptic Plasticity in the Medial Prefrontal Cortex

Authors: Zhuo‐jin Yang, Dong‐yu Yu, Fei‐fei Gao, Dan‐ya Zhou, Ya‐nan Wu, Xi‐xi Yang, Jie Chen, Jing‐si Yang, Meng‐qing Shen, Yu‐xiang Zhang, Lai Wei, Chun‐xia Yan

Source: Advanced Science, Vol 12, Iss 10, Pp n/a-n/a (2025)

Subject Terms: Fscn1, histone demethylase KDM7A, medial prefrontal cortex, morphine, reward memory, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/f090b93dce6149c88ab58874dae38801

The multifaceted role of post-translational modifications of LSD1 in cellular processes and disease pathogenesis

Authors: Yinrui Li, Bo Wang, Yichao Zheng, Huiqin Kang, Ang He, Lijuan Zhao, Ningjie Guo, Hongmin Liu, Adil Mardinoglu, M.A.A. Mamun, Ya Gao, Xiaobing Chen

Source: Genes and Diseases, Vol 12, Iss 3, Pp 101307- (2025)

Subject Terms: Enzyme activity, Histone demethylase, Human diseases, LSD1, Post-translational modifications, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304224001041; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/439c05ae75084c5b826052de85adadcb

Centromere inactivation during aging can be rescued in human cells

Authors: Sikder, Sweta ¹, Baek, Songjoon ¹, McNeil, Truman ^{1, 2}, Dalal, Yamini ^{1, 3, ∗}

Source: In Molecular Cell 20 February 2025 85(4):692-707

Research progress on histone acetylation/methylation in oral diseases

Authors: LUO Yuchuan, LI Feifei, YU Fanyuan, YIN Bei, YE Ling

Source: 口腔疾病防治, Vol 32, Iss 6, Pp 463-469 (2024)

Subject Terms: histone modification, histone methylation, histone demethylation, histone acetylation, histone deacetylation, histone demethylase inhibitors, histone deacetylase inhibitors, dental fluorosis, periodontitis, pulpitis, Medicine

File Description: electronic resource

Relation: https://www.kqjbfz.com/fileup/2096-1456/PDF/2096-1456（2024）06-463-07.pdf; https://doaj.org/toc/2096-1456

Access URL: https://doaj.org/article/c83ef6d393f2414eb80d6e994ab2d980

ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer

Authors: DiCiaccio, Benedetto ^{1, 2, 3}, Seehawer, Marco ^{1, 2, 3}, Li, Zheqi ^{1, 2, 3}, Patmanidis, Andriana ¹, Bui, Triet ^{1, 2, 3}, Foidart, Pierre ^{1, 2, 3}, Nishida, Jun ^{1, 2, 3}, D’Santos, Clive S. ⁴, Papachristou, Evangelia K. ⁴, Papanastasiou, Malvina ⁵, Reiter, Andrew H. ⁵, Qiu, Xintao ⁶, Li, Rong ⁶, Jiang, Yijia ⁶, Huang, Xiao-Yun ¹, Simeonov, Anton ⁷, Kales, Stephen C. ⁷, Rai, Ganesha ⁷, Lal-Nag, Madhu ⁷, Jadhav, Ajit ⁷, Brown, Myles ^{1, 2, 3}, Carroll, Jason S. ⁴, Long, Henry W. ⁶, Polyak, Kornelia ^{1, 2, 3, 5, 6, 8, 9, ∗}

Source: In Cell Reports 24 December 2024 43(12)

The transcription regulators ZNF750 and LSD1/KDM1A dampen inflammation on the skin’s surface by silencing pattern recognition receptors

Authors: Liu, Ye ¹, Chen, Yifang ¹, Batzorig, Uyanga ¹, Li, Jingting ², Fernández-Méndez, Celia ¹, Mahapatra, Samiksha ¹, Li, Fengwu ¹, Sam, Shebin ¹, Dokoshi, Tatsuya ¹, Hong, Seung-Phil ^{1, 3}, Nakatsuji, Teruaki ¹, Gallo, Richard L. ¹, Sen, George L. ^{1, 4, ∗}

Source: In Immunity 8 October 2024 57(10):2296-2309

H3K4 demethylase SsJMJ11 promotes flowering in sugarcane

Authors: Chen, Daoqian ^{a, 1}, Yu, Guangrun ^{a, b, 1}, Wu, Xiaoge ^{a, 1}, Ye, Meiling ^a, Wang, Qiongli ^{a, ⁎}

Source: In Industrial Crops & Products 15 September 2024 216

Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

Authors: Guak, Hannah ^{1, 2, 8}, Weiland, Matthew ^{1, 8}, Ark, Alexandra Vander ¹, Zhai, Lukai ¹, Lau, Kin ³, Corrado, Mario ^{1, 4}, Davidson, Paula ¹, Asiedu, Ebenezer ¹, Mabvakure, Batsirai ^{1, 5, 6}, Compton, Shelby ¹, DeCamp, Lisa ¹, Scullion, Catherine A. ^{1, 7}, Jones, Russell G. ¹, Nowinski, Sara M. ¹, Krawczyk, Connie M. ^{1, 9, ∗}

Source: In Cell Reports 27 August 2024 43(8)

The roles of histone methylation in the regulation of abiotic stress responses in plants

Authors: Lei Shi, Xiaoyun Cui, Yuan Shen

Source: Plant Stress, Vol 11, Iss , Pp 100303- (2024)

Subject Terms: Abiotic stress, Histone methylation, Histone methyltransferase, Histone demethylase, Epigenetic memory, Metabolic regulation, Plant ecology, QK900-989

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667064X23001707; https://doaj.org/toc/2667-064X

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Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5

Authors: Matanel Yheskel, Simone Sidoli, Julie Secombe

Source: Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-16 (2023)

Subject Terms: KDM5, Histone demethylase, TurboID, Proximity labeling, Mass spectrometry, Chromatin modifiers, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8935

Access URL: https://doaj.org/article/58e77dd544d441039134b2ff7d072bf7

Histone demethylase KDM4B contributes to advanced clear cell renal carcinoma and association with copy number variations and cell cycle progression

Authors: Heting Tang, Yaping Guan, Zhihao Yuan, Tuanjie Guo, Xiangyin Tan, Yu Fan, Encheng Zhang, Xiang Wang

Source: Epigenetics, Vol 18, Iss 1 (2023)

Subject Terms: renal cancer, epigenetics, histone demethylase 4b, copy number variation, cell cycle, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/9cb3f8f6fc734ff19163084e83c3c06c

Methylation of the epigenetic JMJD2D protein by SET7/9 promotes prostate tumorigenesis

Authors: Ruicai Gu, Tae-Dong Kim, Hanlin Jiang, Sook Shin, Sangphil Oh, Ralf Janknecht

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: CBLC, gene expression, histone demethylase, KDM4D, PLAGL1, posttranslational modification, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1295613/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/98703971f8d74952b58ab49316928a02

LSD2 Is an Epigenetic Player in Multiple Types of Cancer and Beyond

Authors: Hyun-Min Kim, Zifei Liu

Source: Biomolecules, Vol 14, Iss 5, p 553 (2024)

Subject Terms: LSD2, KDM1B, AOF1, LSD1, KDM1A, histone demethylase, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/5/553; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/42e123ffb5b94a7898edf678453e4e04

Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

Authors: Rossella Fioravanti, Veronica Rodriguez, Jonatan Caroli, Ugo Chianese, Rosaria Benedetti, Elisabetta Di Bello, Beatrice Noce, Clemens Zwergel, Davide Corinti, Dolores Viña, Lucia Altucci, Andrea Mattevi, Sergio Valente, Antonello Mai

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 973-985 (2022)

Subject Terms: Epigenetics, histone demethylase, anticancer activity, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/93fcd4f9950b49e69e71b43501b4fcde

Analysis on Cloning and Expression of Histone Demethylase Gene OsJMJ719 in Rice

Authors: Junting JIA, Bingxian CHEN, Rouxian WU, Zhangyan DAI, Mingsheng ZHONG, Hao XIE, Shuangxing LIU, Jun LIU

Source: Guangdong nongye kexue, Vol 49, Iss 11, Pp 152-161 (2022)

Subject Terms: rice, osjmj719, histone demethylase, gene cloning, expression analysis, Agriculture

File Description: electronic resource

Relation: http://gdnykx.cnjournals.org/gdnykx/ch/reader/view_abstract.aspx?file_no=202211016; https://doaj.org/toc/1004-874X

Access URL: https://doaj.org/article/6ff7473747444a6889c3ed2f35103ab6

Histone demethylase KDM5A regulates the functions of human periodontal ligament stem cells during periodontitis via the miR-495-3p/HOXC8 axis

Authors: Fang Niu, Jing Xu, Yujuan Yan

Source: Regenerative Therapy, Vol 20, Iss , Pp 95-106 (2022)

Subject Terms: Periodontitis, hPDLSCs, Histone demethylase, KDM5A, miR-495-3p, Stem cell function, Medicine (General), R5-920, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352320421000997; https://doaj.org/toc/2352-3204

Access URL: https://doaj.org/article/1d293448bb3945768b552133bb968c28

Relationship between histone demethylase LSD family and development and prognosis of gastric cancer

Authors: Liyan Dong, Jiaxing Zhu, Anyi Deng, Junping Wei, Jiawei Li, Xinru Mao, Zhenghu Jia

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: gastric cancer, histone modification, histone demethylase, protein structure, catalytic mechanism, biological function, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1170773/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/60bde31fb1a8487ebf356216786eb3bf

Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles

Authors: Lea M. Stitzlein, Achintyan Gangadharan, Leslie M. Walsh, Deokhwa Nam, Alexsandra B. Espejo, Melissa M. Singh, Kareena H. Patel, Yue Lu, Xiaoping Su, Ravesanker Ezhilarasan, Joy Gumin, Sanjay Singh, Erik Sulman, Frederick F. Lang, Joya Chandra

Source: Frontiers in Neurology, Vol 14 (2023)

Subject Terms: histone demethylase inhibitors, epigenetics, lysine specific demethylase (KDM), glioblastoma, drug resistance, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2023.1112207/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/8cf1141c8fd94cffbd85efb1ee005dde