The mechanism of high mobility group box-1 in the proliferation and macrophage polarization in esophageal squamous cell carcinoma cells

Authors: Liling Luo, Chao Jiang, Songxi Xie

Source: European Journal of Medical Research, Vol 30, Iss 1, Pp 1-13 (2025)

Subject Terms: High mobility group box 1, Proliferation, Macrophage polarization, Insulin-like growth factor binding protein 3/DNA-dependent protein kinase catalytic subunit axis, Esophageal squamous cell carcinoma, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/1d1eaa833e714124996209fb391a4693

Serial cerebrospinal fluid concentrations of high mobility group box 1 in bacterial meningitis: a retrospective cohort study

Authors: Takeshi Matsushige, Hirofumi Inoue, Madoka Hoshide, Fumitaka Kohno, Hikaru Kobayashi, Kiyoshi Ichihara, Takashi Ichiyama, Shunji Hasegawa

Source: BMC Infectious Diseases, Vol 25, Iss 1, Pp 1-10 (2025)

Subject Terms: Bacterial meningitis, Cerebrospinal fluid, High mobility group box 1, Cytokine, Prognosis, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/1b846f4336e44bb48aa2c2d2eeb22043

High mobility group box 1 in the central nervous system: regeneration hidden beneath inflammation

Authors: Hanki Kim, Bum Jun Kim, Seungyon Koh, Hyo Jin Cho, Xuelian Jin, Byung Gon Kim, Jun Young Choi

Source: Neural Regeneration Research, Vol 20, Iss 1, Pp 107-115 (2025)

Subject Terms: central nervous system, damage-associated molecular pattern, ethyl pyruvate, glycyrhizzin, high mobility group box 1, inflammation, neural stem cells, neurodevelopment, oligodendrocyte progenitor cells, redox status, regeneration, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://journals.lww.com/10.4103/NRR.NRR-D-23-01964; https://doaj.org/toc/1673-5374; https://doaj.org/toc/1876-7958

Access URL: https://doaj.org/article/1c95b644f6ae42e9a394b6d69a3b3241

Dual alarmin-receptor-specific targeting peptide systems for treatment of sepsis

Authors: Seok-Jun Mun, Euni Cho, Woo Jin Gil, Seong Jae Kim, Hyo Keun Kim, Yu Seong Ham, Chul-Su Yang

Source: Acta Pharmaceutica Sinica B, Vol 14, Iss 12, Pp 5451-5463 (2024)

Subject Terms: Sepsis, High mobility group box 1, Pentraxin 3, Liposome, Antibiotics, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383524003344; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/98d4ee0fd71b4942a5258ba3ae527783

High Translocation of High Mobility Group Box 1 in the Brain Tissue of Patients with Sturge-Weber Syndrome

Authors: Cheng Z, Li X, Wang S, Sun W, Pan J, Wang X, Zhou J, Li T, Luan G, Guan Y

Source: Journal of Inflammation Research, Vol Volume 17, Pp 9347-9358 (2024)

Subject Terms: high mobility group box 1, translocation, sturge weber syndrome, drug-resistant epilepsy, cell subtype, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/high-translocation-of-high-mobility-group-box-1-in-the-brain-tissue-of-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Access URL: https://doaj.org/article/2b3b02774ca14dd4a4f0665cead1ba49

The lactate metabolism and protein lactylation in epilepsy

Authors: Xi Kuang, Shuang Chen, Qingmei Ye

Source: Frontiers in Cellular Neuroscience, Vol 18 (2025)

Subject Terms: protein lactylation, histone deacetylase, epilepsy, high-mobility group box 1, hypoxia-inducible factor-1α, lactate, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fncel.2024.1464169/full; https://doaj.org/toc/1662-5102

Access URL: https://doaj.org/article/3597d4b76aaa47e393433225b65baea9

MiR- 146b-5p inhibits Candida albicans-induced inflammatory response through targeting HMGB1 in mouse primary peritoneal macrophages

Authors: Jing Cheng, Xiaoxing Tian, Chuanxin Wu, Jiaojiao Wang, Huiling Liu, Sha Cheng, Hang Sun

Source: Heliyon, Vol 11, Iss 1, Pp e41464- (2025)

Subject Terms: Candida albicans, High mobility group box 1, miRNAs, Inflammation, NF-κB, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024174956; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/d0521748aefb4369a1220011c302afff

Roles of HMGB1 on life-threatening traumatic brain injury and sequential peripheral organ damage

Authors: Chihiro Kawai, Masashi Miyao, Hirokazu Kotani, Hirozo Minami, Hitoshi Abiru, Keiji Tamaki, Yoko Nishitani

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Subject Terms: Traumatic brain injury, Weight drop model, Multiple organ injury, High mobility group box 1, Peripheral immune suppression, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5a4c530b40274b9fb325990ac4fd5cd1

Elevated Serum HMGB1 Levels and Their Association with Recurrence of Acute Ischaemic Stroke

Authors: Shen L, Yang J, Zhu Z, Li W, Cui J, Gu L

Source: Journal of Inflammation Research, Vol Volume 17, Pp 6887-6894 (2024)

Subject Terms: high mobility group box 1, acute ischemic stroke, recurrence, Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/elevated-serum-hmgb1-levels-and-their-association-with-recurrence-of-a-peer-reviewed-fulltext-article-JIR; https://doaj.org/toc/1178-7031

Access URL: https://doaj.org/article/319d16bcf0b3488db4eec8f1d18a8583

The Role of Alarmins in the Pathogenesis of Atherosclerosis and Myocardial Infarction

Authors: Kajetan Kiełbowski, Patryk Skórka, Paulina Plewa, Estera Bakinowska, Andrzej Pawlik

Source: Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8995-9015 (2024)

Subject Terms: atherosclerosis, myocardial infarction, alarmins, high-mobility group box 1, S100 proteins, interleukin-33, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/8/532; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/fb702b748ce34f378a5ef76cd6f6886d

Feature Paper in Physiology and Pathology

Contributors: Roumeliotis, Stefanos, Minervini, Giuseppe

Subject Terms: kidney fibrosis, chronic kidney disease, TGFβR-1, flavonoids, pharmacokinetics, molecular docking, molecular dynamics simulations, retrospective cohort study, kidney disease, end-stage kidney disease, vitamin D, tuberculosis, type 2 diabetes mellitus, genetic susceptibility, molecular chaperons, heat shock factor 1 (HSF1), single nucleotide polymorphism, gene expression, protein folding, unfolded protein response, body mass index, obesity, sex dimorphism, NF-κB signaling, signaling dynamics, cell-fate decision, encoding and decoding, cellular information, human diseases, prolyl hydroxylase domain-containing protein, PHD protein, Phd1 gene, osteoblast, chondrocyte, knockout mice, phenotype, hypoxia-inducible factor, endochondral bone formation, MRI, prefrontal areas, putamen, gray matter volume, specific phobia, cognition, rice intake, adults, Qatar Biobank study, Neoplasia, exercise, sensitivity, chemotherapy, measurement of results reported by the patient, biomechanics, osteoarthritis, cartilage, musculoskeletal simulation, probabilistic modelling, experimental autoimmune encephalomyelitis, colitis, growth factors, nematode adaptation, angiogenesis, knee joint, biomarkers, extracellular vesicles, sepsis, coagulation, disseminated intravascular coagulation, sepsis-induced coagulopathy, laboratory evaluation, guidelines, cell competition, cellular Potts model, invasion, travelling wave, neutrophil extracellular traps, peripheral blood, infection, digital white blood cell differential, genetic disease, prevalence, penetrance, accurate diagnosis, disease iceberg effect, cumulative lifetime risk, familial aggregation, ozone, ozone therapy, oxidative stress, antioxidants defense, inflammation, dupilumab, biologic, dermatitis, lichen amyloidosis, primary cutaneous amyloidosis, primary localized cutaneous amyloidosis, IgG4-related disease, IgG4-related skin disease, immunoglobulin G4-related disease, immunoglobulin G4-related skin disease, WNT16, chondrocytes, mice, chondrogenesis, cell culture, subarachnoid hemorrhage, bone-marrow mesenchymal stem cells, cognitive impairment, high-mobility group box 1, central centrifugal cicatricial alopecia, scarring alopecia, pediatric, scarring hair loss, skin of colour, public health, ambulatory blood pressure, antihypertensive therapy, peritoneal dialysis, sex differences, geranylgeraniol, GGOH, bisphosphonates, medication-related osteonecrosis of the jaw, MRONJ, mevalonate pathway, platelets, PEVs, hemostasis, wound healing, carcinogenesis, therapy, imidacloprid, apoptosis, telencephalon, zebrafish, serous endometrial intraepithelial carcinoma, SEIC, MUSC, adjuvant therapy, relapse, BK-polyomavirus, decoy cell, polyoma nephropathy, large T antigen, VP1, complications, congenital heart disease, ECMO, extracorporeal life support, mortality, risk factors, single ventricle, BOLD signal variability, pediatrics, biomarker, fMRI, neurodevelopment, grip strength, young children, active play, growth and development, platelet-rich plasma, rhein, knee osteoarthritis, Crohn’s disease, intestinal ultrasonography, contrast-enhanced ultrasound, MR enterography, depressive disorders, cognitive function, physical function, dementia, older people, copepods, lipidomics, climate change, oceanic food chain, sentinel species, patient blood management, red blood cell, transfusion, hemoglobin, retrospective study, social isolation, space radiation, blood–brain barrier, lateral ventricle, post-stroke depression, behavioral tests, social activity, motor function, antidepressants, murine models of depression, Theatre studies, Music

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/152786
https://mdpi.com/books/pdfview/book/10019

Glycyrrhizin alleviates brain injury in necrotizing enterocolitis model mice by suppressing HMGB1/TLR4 pathway

Authors: Sun, Qian ^{a, b, c, d, e}, Li, Ling ^{a, b, c, d, e}, Li, Jing ^{a, b, c, d, e}, Li, Si-yu ^{a, b, c, d, e}, Zhang, Yan ^{a, b, c, d, e}, Chen, Xin-si ^{a, b, c, d, e}, Liu, Sha-sha ^{a, b, c, d, e}, Hua, Zi-yu ^{a, b, c, d, e, ⁎}

Source: In International Immunopharmacology 26 March 2025 150

Tumor Necrosis Factor-α–Dependent Inflammation Upregulates High Mobility Group Box 1 To Induce Tumor Promotion and Anti–Programmed Cell Death Protein-1 Immunotherapy Resistance in Lung Adenocarcinoma

Authors: Kang, Lifei ^{a, b}, Cao, Jingjing ^{a, c, d}, Guo, Wenli ^{a, e}, Cui, Xiaohui ^{a, c}, Wei, Yangxuan ^c, Zhang, Jiayu ^c, Liu, Feiran ^f, Duan, Chenyang ^{a, c}, Lin, Qiang ^g, Lv, Ping ^h, Ni, Zhiyu ^{i, j, k, ∗}, Zuo, Jing ^{c, f, k, ∗}, Shen, Haitao ^{a, c, k, ∗}

Source: In Laboratory Investigation February 2025 105(2)

Lipocalin-2 aggravates blood-brain barrier dysfunction after intravenous thrombolysis by promoting endothelial cell ferroptosis via regulating the HMGB1/Nrf2/HO-1 pathway

Authors: Jie Liu, Shu-Yan Pang, Sheng-Yu Zhou, Qian-Yan He, Ruo-Yu Zhao, Yang Qu, Yi Yang, Zhen-Ni Guo

Source: Redox Biology, Vol 76, Iss , Pp 103342- (2024)

Subject Terms: Hemorrhagic transformation, Lipocalin-2, Blood-brain barrier, Ferroptosis, High mobility group box 1, Intravenous thrombolysis, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231724003203; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/ed5b1f5709cd4b76bf6410e65e5391c9

An early HMGB1 rise 12 hours before creatinine predicts acute kidney injury and multiple organ failure in a smoke inhalation and burn swine model

Authors: Zhangsheng Yang, Tomas S. Cancio, Robert P. Willis, Matthew D. Young, Dustin M. Kneifel, Jose Salinas, Andrew D. Meyer

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: high-mobility group box 1, acute kidney injury, multiple organ failure, swine, polytrauma, inflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1447597/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e082b22a9e97483098e13d81cffc8733

Enhancement of tracheal cartilage regeneration by local controlled release of stromal cell-derived factor 1α with gelatin hydrogels and systemic administration of high-mobility group box 1 peptide

Authors: Kumiko (Ogi) Suzuki, Tatsuya Okamoto, Katsuto Tamai, Yasuhiko Tabata, Etsuro Hatano

Source: Regenerative Therapy, Vol 26, Iss , Pp 415-424 (2024)

Subject Terms: High-mobility group box 1 peptide, Mesenchymal stem cell, Stromal cell-derived factor-1α, Endogenous regenerative therapy, Tracheobronchomalacia, Gelatin hydrogel, Medicine (General), R5-920, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235232042400124X; https://doaj.org/toc/2352-3204

Access URL: https://doaj.org/article/cb98c019f17d429cad951e90339feeb8

Investigation of the hydromechanical threshold of high-mobility group box 1 release from synovial cells and chondrocytes

Authors: TONG Qiaoying, SHAO Bo, XU Yingjie, JIA Mengying, MA Youyi, GONG Zhongcheng

Source: 口腔疾病防治, Vol 32, Iss 6, Pp 411-419 (2024)

Subject Terms: temporomandibular joint osteoarthritis, synovial cells, chondrocytes, fluid flow shear stress, threshold, high-mobility group box 1, interleukin-1β, Medicine

File Description: electronic resource

Relation: https://www.kqjbfz.com/fileup/2096-1456/PDF/2096-1456（2024）06-411-09.pdf; https://doaj.org/toc/2096-1456

Access URL: https://doaj.org/article/632e2ab4df62421e806f225a41f69b35

Glycyrrhizic Acid Showed Therapeutic Effects on Severe Pulmonary Damages in Mice Induced by Pneumonia Virus of Mice Infection

Authors: LIU Yun, FENG Tingting, TONG Wei, GUO Zhi, LI Xia, KONG Qi, XIANG Zhiguang

Source: Shiyan dongwu yu bijiao yixue, Vol 44, Iss 3, Pp 251-258 (2024)

Subject Terms: glycyrrhizic acid, high mobility group box 1, pneumonia virus of mice, lung damage, balb/c mice, Medicine

File Description: electronic resource

Relation: https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2024.014; https://doaj.org/toc/1674-5817

Access URL: https://doaj.org/article/e5f11206a94c475f940e9195b12253f2

Analysis of changes in high‐mobility group box 1, receptor for advanced glycation endproducts, and T helper 17/regulatory T balance in severe preeclampsia with acute heart failure

Authors: Chen De, Liang Xuan, Zhang jingjing, Zhang Honghong, Zuo Kun, Du Song, Song Yaqi, Jiang Ying, Cheng Cheng, Liu Jian

Source: The Journal of Clinical Hypertension, Vol 26, Iss 4, Pp 431-440 (2024)

Subject Terms: acute heart failure, high‐mobility group box 1 protein, receptor for advanced glycation endproducts, severe preeclampsia, Th17/Treg, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1524-6175; https://doaj.org/toc/1751-7176

Access URL: https://doaj.org/article/16fb42e0814a4430b6af76b6223ec68b

The Role of Alarmins in the Pathogenesis of Rheumatoid Arthritis, Osteoarthritis, and Psoriasis

Authors: Kajetan Kiełbowski, Wiktoria Stańska, Estera Bakinowska, Marcin Rusiński, Andrzej Pawlik

Source: Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3640-3675 (2024)

Subject Terms: alarmins, high-mobility group box 1, S100 proteins, rheumatoid arthritis, osteoarthritis, psoriasis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/4/228; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/4f8a9a5492e94fb7b782c618a8987b82