Exploring Novel Plumbagin Derivatives as Potential Inhibitors For HepG2 Cell Line Using QSAR And Molecular Docking Models

Authors: Quang, Nguyen Minh, Minh, Nguyen Hoang, Van Tat, Pham

Source: 2023 1st International Conference on Health Science and Technology (ICHST) Health Science and Technology (ICHST), 2023 1st International Conference on. :1-6 Dec, 2023

Relation: 2023 1st International Conference on Health Science and Technology (ICHST)

New tetrahydroisoquinolines bearing nitrophenyl group targeting HSP90 and RET enzymes: synthesis, characterization and biological evaluation

Authors: Etify A. Bakhite, Reda Hassanien, Nasser Farhan, Eman M. Sayed, Marwa Sharaky

Source: BMC Chemistry, Vol 19, Iss 1, Pp 1-20 (2025)

Subject Terms: Anticancer, Apoptosis, Cell cycle, RET enzyme (rearranged during transfection) enzyme, Heat shock protein (HSP90) enzyme, HEPG2 cell line, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2661-801X

Access URL: https://doaj.org/article/905045953f9a48409bcd15903cc2420f

Evaluation of potentially toxic elements and pharmaceutical compounds in leachate and exhaust air from non-incineration medical waste treatment devices

Authors: Zohreh Bahmani, Ramin Nabizadeh, Kamyar Yaghmaeian, Masud Yunesian

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

Subject Terms: Cytotoxicity, HepG2, A549, Potentially toxic elements, Non-incineration, Hospital waste, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9df98989d310414bbbff920f902a398b

Experimental study of iodine-131 labeling of a novel tumor-targeting peptide, TFMP-Y4, in the treatment of hepatocellular carcinoma with internal irradiation

Authors: Juan Du, Weiwei Ren, Wenjie Liu, Yixuan Zhou, Yushan Li, Qingyi Lai, Xiongying Liu, Tongsheng Chen, Wenjuan Liu, Zhuanming Chen, Jinhe Zhang, Peipei Zhang, Jianwei Yuan

Source: BMC Cancer, Vol 25, Iss 1, Pp 1-12 (2025)

Subject Terms: Modified polypeptide, Caerin polypeptide, Iodine-131 labeling, Hepg2 cells, In vitro therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/61c83009242b46cbbd5c1d3653cccff0

Investigation of the Cytotoxic Effect of A New N-Phenyl Benzimidazole Derivative on Cell Viability in A549 and HepG2 Cell Lines

Authors: Esra Bilici, Senem Akkoç

Source: Van Tıp Dergisi, Vol 32, Iss 1, Pp 3-6 (2025)

Subject Terms: cytotoxic activity, n-phenyl benzimidazole, hepg2, a549, cisplatin, Medicine

File Description: electronic resource

Relation: https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vmj&un=VMJ-58077; https://doaj.org/toc/2587-0351

Access URL: https://doaj.org/article/5ef22a722cb84b4bafaaccf7970cb63e

Calcium hydroxide nanoparticles induce cell death, genomic instability, oxidative stress and apoptotic gene dysregulation on human HepG2 cells

Authors: Hanan R. H. Mohamed, Esraa H. Ibrahim, Shahd E. E. Shaheen, Nesma O. E. Hussein, Ayman Diab, Gehan Safwat

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

Subject Terms: Calcium hydroxide nanoparticles, DNA breaks, ROS generation, Apoptosis induction, HSF and HepG2 cells, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/919817befed6450c8e1a760ccae973f1

Tolterodine is a novel candidate for assessing CYP3A4 activity through metabolic volatiles to predict drug responses

Authors: Valentina Stock, Rebecca Hofer, Franziska Lochmann, Vera Spanke, Klaus R. Liedl, Jakob Troppmair, Thierry Langer, Hubert Gstach, Christian Dank, Chris A. Mayhew, Sarah Kammerer, Veronika Ruzsanyi

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

Subject Terms: Breath test, CYP3A4, HepG2, Tolterodine, Acetone, Volatile biomarkers, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/c331948a591b4c32beff2a1a76ba3a01

Unveiling the potential anticancer activity of Spirulina maxima extract-nanoemulsion through in vitro and in vivo studies

Authors: Mohammed Yasser Hussein, Merna Nasr, Veronia Emad, Julie Maged, Portia George, Amina Emad, Abeer Mahmoud Badr, Mehrez E. El-Naggar, Sayeda M. Abdo, Jihan Hussein

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-18 (2025)

Subject Terms: miR-221-3p, miR-222-3p, HepG2 cells, MCF-7 cells, Gallic acid, EAC model, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ea9d1ed1c6ca478b97f22b485c2274b3

Anticancer Activity Of Ginger Oleoresin Against Liver cancer Cell Line

Authors: Arsath, N. Mohamed, Roya, Anitha, Raghunandhakumar, S.

Source: 2023 International Conference on Business Analytics for Technology and Security (ICBATS) Business Analytics for Technology and Security (ICBATS), 2023 International Conference on. :1-4 Mar, 2023

Relation: 2023 International Conference on Business Analytics for Technology and Security (ICBATS)

Niosome as a Drug Delivery Carrier for Sorafenib: Preparation, Investigation of Physicochemical Properties, and In Vitro Effects on HepG2 Cell Line

Authors: Mohammad Amin Raeisi Estabragh, Behzad Behnam, Masoud Torkzadeh-Mahani, Abbas Pardakhty

Source: Advanced Pharmaceutical Bulletin, Vol 14, Iss 4, Pp 836-845 (2024)

Subject Terms: hepg2 cell line, niosome, sorafenib, target drug delivery, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://apb.tbzmed.ac.ir/PDF/apb-14-836.pdf; https://doaj.org/toc/2228-5881; https://doaj.org/toc/2251-7308

Access URL: https://doaj.org/article/0bdb4f01c76846cc99c9d8581a6d5ff8

Prediction of bioactive compounds hepatotoxicity using in silico and in vitro analysis

Authors: Kwanyong Choi, Soyeon Lee, Sunyong Yoo, Hyoung-Yun Han, Soo-yeon Park, Ji Yeon Kim

Source: Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-13 (2024)

Subject Terms: Drug-induced liver injury, Prediction, In silico, HepG2, Hepatotoxicity, Agriculture (General), S1-972, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2468-0842

Access URL: https://doaj.org/article/22f615c6ae5e46908a8197ab2e16efb0

Multiomics Analysis of Molecules Associated with Cancer in Mesenchymal-Stem-Cell-(MSC)-Derived Exosome-Treated Hepatocellular Carcinoma Cells

Authors: Wen-Yong Gao, Chantana Boonyarat, Nutjakorn Samar, Benjabhorn Sethabouppha, Pornthip Waiwut

Source: Current Issues in Molecular Biology, Vol 46, Iss 12, Pp 13296-13310 (2024)

Subject Terms: UC-MSCs, HepG2 cells, RNA sequencing analysis, exosomal proteins, neutrophil extracellular trap formation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/12/793; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/2eec2cedceb842d98d3255c69d23c54a

Polysaccharide-rich extract of Potentilla anserina ameliorates nonalcoholic fatty liver disease in free fatty acid-induced HepG2 cells and high-fat/sugar diet-fed mice

Authors: Xiujun Lin, Yimei Zheng, Yingying Yan, Hongting Deng, Shunxin Wang, Yuanju He, Yuting Tian, Wenhui Zhang, Hui Teng

Source: Food Science and Human Wellness, Vol 13, Iss 6, Pp 3351-3360 (2024)

Subject Terms: potentilla anserina l., non-alcoholic fatty liver disease, lipid accumulation, hepg2 cells, high fat diet, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.sciopen.com/article/10.26599/FSHW.2023.9250020; https://doaj.org/toc/2097-0765; https://doaj.org/toc/2213-4530

Access URL: https://doaj.org/article/c715697e8df54f5790218e61a8ff4124

Toxic Effects of Synthesized Bismuth Oxide/Reduced Graphene Oxide (Bi2O3/RGO) Nanocomposites in Two Distinct Mammalian Cell Lines: Role Oxidative Stress and Apoptosis

Authors: Lateef R, Ahmad I, Mahdi AA, Lohia N, Alhadlaq HA, Akhtar MJ, Ahamed M

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 12655-12674 (2024)

Subject Terms: bi2o3/rgo nanocomposites, health effects, nrk52e, hepg2, caspase-3, ros, apoptosis, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/toxic-effects-of-synthesized-bismuth-oxidereduced-graphene-oxide-bi2o3-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/9fcb89da97e4494aa9da9797e30a6265

Protective Effect of Probiotic-fermented Gardenia jasminoides Ellis against Alcoholic Oxidative Damage in HepG2 Cells

Authors: Jingru LIAO, Jing YAN, Wenjun ZHAO, Dongqiu CHEN, Lieyu WANG, Qilin ZHANG, Bing DU, Pan LI

Source: Shipin gongye ke-ji, Vol 45, Iss 21, Pp 350-357 (2024)

Subject Terms: bacillus sp. du-106, liver injury, oxidative stress, anti-inflammatory, hepg2 cells, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://doaj.org/toc/1002-0306

Access URL: https://doaj.org/article/b7c0e10a0b834846a52c103eb64abd3f

Isolation of highly polar galloyl glucoside tautomers from Saxifraga tangutica through preparative chromatography and assessment of their in vitro antioxidant activity

Authors: Yingying Tong, Ming Chu, Jia Zhou, Qilan Wang, Gang Li, A. M. Abd El-Aty, Jun Dang

Source: BMC Chemistry, Vol 18, Iss 1, Pp 1-12 (2024)

Subject Terms: Saxifraga tangutica, Isolation, Galloyl glucoside tautomers, Antioxidative activity, HepG2 cells, Structure‒activity relationships, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2661-801X

Access URL: https://doaj.org/article/402d24a51d5d4678a6e2c268c8a42387

The effect of gelatinized brown rice extract on type 2 diabetes mellitus via inhibition of insulin resistance mediators in HepG2 cells

Authors: Min Ho Kang, Ha Young Park, Yeop Jang, Jung Eun Park, Jin Woo Kim

Source: Discover Food, Vol 4, Iss 1, Pp 1-13 (2024)

Subject Terms: Gelatinized brown rice extract, Type 2 diabetes mellitus, Insulin resistance, Glucose transport, HepG2 cells, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://doaj.org/toc/2731-4286

Access URL: https://doaj.org/article/fb96862784f042e7923e4ced71d89a83

Citronellol Attenuates High Glucose-Induced Oxidative Stress and Inflammatory Responses in HepG2 Cells

Authors: Razieh Choghakhori, Mojgan Azadpour, Amir Abbasnezhad, Farzad Ebrahimzadeh, Hassan Ahmadvand

Source: Cell Journal, Vol 26, Iss 10, Pp 602-610 (2024)

Subject Terms: citronellol, hepg2 cells, hyperglycemia, inflammation, oxidative stress, Medicine, Science

File Description: electronic resource

Relation: https://www.celljournal.org/article_721279_d41d8cd98f00b204e9800998ecf8427e.pdf; https://doaj.org/toc/2228-5806; https://doaj.org/toc/2228-5814

Access URL: https://doaj.org/article/9114e98ee8ff4497a814212283dcd222

Preliminary Study on Lutetium-177 and Gold Nanoparticles: Apoptosis and Radiation Enhancement in Hepatic Cancer Cell Line

Authors: Maria Anthi Kouri, Anastasios Georgopoulos, George E. Manios, Eirini Maratou, Aris Spathis, Sofia Chatziioannou, Kalliopi Platoni, Efstathios P. Efstathopoulos

Source: Current Issues in Molecular Biology, Vol 46, Iss 11, Pp 12244-12259 (2024)

Subject Terms: gold nanoparticles, Lutetium-177, radionuclide therapy, molecular therapy, HepG2 cancer cell line, gold nanospheres, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/11/727; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/4ad66ca9bc324fc1bf0e9335879bc020

Role and Mechanism of 20-Hydroxyecdysone in Oxidative Damage of HepG2 Cells Induced by High Glucose

Authors: Mengyuan WANG, Xianjun LIU, Xianglong MENG, Hao LI, Zhandong LI, Yuhe YIN

Source: Shipin gongye ke-ji, Vol 45, Iss 20, Pp 369-377 (2024)

Subject Terms: 20-hydroxyecdysone, high glucose, hepg2 cells, oxidative stress, pi3k/akt signaling pathway, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://doaj.org/toc/1002-0306

Access URL: https://doaj.org/article/c6a59c7cac334adc8cf9e26502373d80