Semisynthetic derivatives of haemanthamine and their in vitro antiproliferative activity evaluation against a panel of human cell lines

Authors: Martin Uher, Miloš Hroch, Rozálie Peřinová, Radim Havelek, Jana Křoustková, Martina Řezáčová, Darina Muthná, Darja Koutová, Jiří Kuneš, Lucie Cahlíková

Source: Arabian Journal of Chemistry, Vol 15, Iss 5, Pp 103746- (2022)

Subject Terms: Haemanthamine, Amaryllidaceae alkaloids, 11-O-(4-chloro-3-nitrobenzoyl)haemanthamine, Antiproliferative activity, Cytotoxicity, In vitro, Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1878535222000624; https://doaj.org/toc/1878-5352

Access URL: https://doaj.org/article/0b444150ae55421aa2d68d3af1eaeb57

Recent Development of Electrospinning for Drug Delivery

Authors: Zelkó, Romána, Lamprou, Dimitrios A., Sebe, István

Subject Terms: R5-920, RM1-950, antibacterial activity, piroxicam, tissue engineering, biotechnology, polydextrose, solvent casting, antibacterial, drug delivery, diabetic, pectin, nanotechnology, nanocomposite, hydroxypropyl methyl cellulose, poorly water-soluble drug, artificial red blood cells, oral dosage form, Lactobacillus, scanning electron microscopy, wound healing, UV imaging, wetting, biocompatibility, scale-up, polylactide-co-polycaprolactone, nanofibers, growth factor, drug release kinetics, hydrogel, differential scanning calorimetry, bacterial bioreporters, physical solid-state properties, PCL, coaxial spinning, drug delivery system, haemanthamine, probiotics, amphiphilic nanofibers, wound dressings, grinding, scanning white light interferometry, biopharmaceuticals, clove essential oil, viability, plant-origin alkaloid, oligochitosan, local delivery, electrospinning, Lactococcus, self-assembled liposomes, microcapsules, microfibers, nanofiber, in situ drug release, biomedical, core-sheath nanofibers, processability, polymeric carrier, aceclofenac, drying, gentamicin sulfate, traditional electrospinning, electrospinning and electrospray, fourier transform infrared spectroscopy, drug release, gelatin, ultrasound-enhanced electrospinning, 3D printing, Medicine and Nursing

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/57765
https://mdpi.com/books/pdfview/book/2145

Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro

Authors: Kateřina Hradiská Breiterová, Aneta Ritomská, Diana Fontinha, Jana Křoustková, Daniela Suchánková, Anna Hošťálková, Marcela Šafratová, Eliška Kohelová, Rozálie Peřinová, Rudolf Vrabec, Denise Francisco, Miguel Prudêncio, Lucie Cahlíková

Source: Pharmaceutics, Vol 15, Iss 3, p 1007 (2023)

Subject Terms: alkaloids, Amaryllidaceae, ambelline, cytotoxicity, haemanthamine, hepatic stage, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/3/1007; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/5d092062cf334c5a91abe4f5fd1bdbb9

Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells

Authors: Veronique Mathieu, Breana Laguera, Marco Masi, Sara Adriana Dulanto, Tanner W. Bingham, Lucas W. Hernandez, David Sarlah, Antonio Evidente, Denis L. J. Lafontaine, Alexander Kornienko, Michelle A. Lane

Source: Biomolecules, Vol 12, Iss 9, p 1267 (2022)

Subject Terms: colorectal cancer, Amaryllidaceae, narciclasine, pancratistatin, lycorine, haemanthamine, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/9/1267; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/b9b5ab1ef3e34de6aeefbfe47a867b39

The Chemical Synthesis of the Crinine and Haemanthamine Alkaloids: Biologically Active and Enantiomerically-Related Systems that Serve as Vehicles for Showcasing New Methodologies for Molecular Assembly

Authors: Nan Hu, Lorenzo V. White, Ping Lan, Martin G. Banwell

Source: Molecules, Vol 26, Iss 3, p 765 (2021)

Subject Terms: alkaloid, crinine, haemanthamine, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/3/765; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/ee5f14614bb546558f93084667c3cb1b

Preformulation Study of Electrospun Haemanthamine-Loaded Amphiphilic Nanofibers Intended for a Solid Template for Self-Assembled Liposomes

Authors: Khan Viet Nguyen, Ivo Laidmäe, Karin Kogermann, Andres Lust, Andres Meos, Duc Viet Ho, Ain Raal, Jyrki Heinämäki, Hoai Thi Nguyen

Source: Pharmaceutics, Vol 11, Iss 10, p 499 (2019)

Subject Terms: haemanthamine, plant-origin alkaloid, electrospinning, amphiphilic nanofibers, self-assembled liposomes, physical solid-state properties, drug release, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/11/10/499; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/c4d373c386604167b451c48843ece46b

Derivatives of the β-Crinane Amaryllidaceae Alkaloid Haemanthamine as Multi-Target Directed Ligands for Alzheimer’s Disease

Authors: Eliška Kohelová, Rozálie Peřinová, Negar Maafi, Jan Korábečný, Daniela Hulcová, Jana Maříková, Tomáš Kučera, Loreto Martínez González, Martina Hrabinova, Katarina Vorčáková, Lucie Nováková, Angela De Simone, Radim Havelek, Lucie Cahlíková

Source: Molecules, Vol 24, Iss 7, p 1307 (2019)

Subject Terms: haemanthamine, Amaryllidaceae, Alzheimer’s disease, acetylcholinesterase, butyrylcholinesterase, glycogen synthase kinase-3β inhibition, docking studies, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/7/1307; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/e5c8419b582741039c32514f94ab04aa

Novel Topologically Complex Scaffold Derived from Alkaloid Haemanthamine

Authors: Karthik Govindaraju, Marco Masi, Margaux Colin, Veronique Mathieu, Antonio Evidente, Todd W. Hudnall, Alexander Kornienko

Source: Molecules, Vol 23, Iss 2, p 255 (2018)

Subject Terms: natural product-like, diversity-oriented synthesis, haemanthamine, haemanthidine, iodoalkoxylation, biological activity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/23/2/255; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/69a47887b9b144639ebfca6fa859370f

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