The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis

Authors: Javier Conde, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Rocío García‐Gómez, Berta Casar, Piero Crespo, Xosé R. Bustelo

Source: Molecular Oncology, Vol 19, Iss 1, Pp 56-80 (2025)

Subject Terms: cholesterol, guanosine nucleotide exchange factors, oncogenic signaling, RAC1, RHO GTPases, sterol regulatory element‐binding protein, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/2c7e929d5aea4d67b1d799eeae224d67

VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma

Authors: Natalia Fernández-Parejo, L. Francisco Lorenzo-Martín, Juana M. García-Pedrero, Juan P. Rodrigo, Mercedes Dosil, Xosé R. Bustelo

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Subject Terms: Guanosine nucleotide exchange factors, RHO GTPases, RAC1, RHOA, PAK1, ROCK, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/cc4d6834c3764ff9ae00a5011ff571bb

Rho GTPases in Skeletal Muscle Development and Homeostasis

Authors: Sonia Rodríguez-Fdez, Xosé R. Bustelo

Source: Cells, Vol 10, Iss 11, p 2984 (2021)

Subject Terms: small G protein, RhoA, Rac1, Cdc42, guanosine nucleotide exchange factors, GTPase activating proteins, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/11/2984; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/e6a95c5e87654111b521eec414bf7d9e

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