Synergistic Genomic Profiling and Predictive Modeling for Health Outcome Anticipation: A Holistic Strategy Leveraging Gene Expression Analysis

Authors: Krishna, Nerella Venkata Anil Rama, Devendra, Vicharapu, Krishna, Dogiparthi Leela, Srikanth, Godavari, Haritha, D

Source: 2023 4th International Conference on Intelligent Technologies (CONIT) Intelligent Technologies (CONIT), 2023 4th International Conference on. :1-5 Jun, 2024

Relation: 2024 4th International Conference on Intelligent Technologies (CONIT)

Real-world data analysis for factors influencing the quality check status in FoundationOne CDx cancer genomic profiling tests

Authors: Hiroaki Niitsu, Hikaru Nakahara, Katsunari Ishida, Yoshie Kaneko, C. Nelson Hayes, Koji Arihiro, Takao Hinoi

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-10 (2025)

Subject Terms: Cancer genomic profiling, FoundationOne CDx, Quality check, Solid tumors, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f77b4827b21540edbb6717c9b8dce3df

Genomic analysis of Enterobacter cloacae complex from Southern Thailand reveals insights into multidrug resistance genotypes and genetic diversity

Authors: Thunchanok Yaikhan, Kamonnut Singkhamanan, Pawarisa Luenglusontigit, Arnon Chukamnerd, Natakorn Nokchan, Nutwadee Chintakovid, Sarunyou Chusri, Rattanaruji Pomwised, Monwadee Wonglapsuwan, Kittinun Leetanaporn, Surasak Sangkhathat, Komwit Surachat

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-13 (2025)

Subject Terms: Enterobacter cloacae complex, Novel ST, Whole genome sequencing, Comprehensive genomic profiling, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/70f4bec5c4df42fdb55355171b43d0ca

Usefulness of Comprehensive Genomic Profiling in Clinical Decision-Making in Oncology: A Systematic Review

Authors: Sewanti Limaye, Jayesh Deshmukh, Nitesh Rohatagi, Kumar Prabhash, Amit Rauthan, Shambhavi Singh, Arun Kumar

Source: Journal of Immunotherapy and Precision Oncology, Vol 8, Iss 1, Pp 55-63 (2025)

Subject Terms: advanced cancer, comprehensive genomic profiling, precision medicine, overall survival, progression-free survival, molecular tumor board, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2666-2345; https://doaj.org/toc/2590-017X

Access URL: https://doaj.org/article/df71a56305a94be4983386b46c35420e

Characterization of the genomic landscape in liver oligometastatic NSCLC

Authors: Rongxin Liao, Guangming Yi, Lu Shen, Xiao Xiao, Chuan Zeng, Liangzhong Liu, Hongjun Tang, Shunping Huang, Xiaoyue Zhang, Zaicheng Xu, Zhenzhou Yang, Yuan Peng

Source: BMC Cancer, Vol 25, Iss 1, Pp 1-11 (2025)

Subject Terms: NSCLC, Liver oligometastasis, Genomic profiling, Next-generation sequencing, Tumor mutational burden, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/62236bf9c825480b96d50a3de9bf3f3b

Expansion of an Academic Molecular Tumor Board to Enhance Access to Biomarker-Driven Trials and Therapies in the Rural Southeastern United States

Authors: Anivarya Kumar, Jennifer R. Owen, Nicholette T. Sloat, Elizabeth Maynard, Vanessa M. Hill, Christopher B. Hubbard, Matthew S. McKinney, Linda M. Sutton, Shannon J. McCall, Michael B. Datto, Ashley N. Moyer, Bennett A. Caughey, John H. Strickler, Ryne C. Ramaker

Source: Current Oncology, Vol 31, Iss 11, Pp 7244-7257 (2024)

Subject Terms: cancer disparities, targeted therapy, molecular profiling, comprehensive genomic profiling, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/31/11/534; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/2311eb1c81e045edb19b30128894b49c

Relevant factors for policy concerning comprehensive genomic profiling in oncology: stakeholder perspectives

Authors: Lucas Frederik van Schaik, Ellen Gurumay Engelhardt, Wim Herbert van Harten, Valesca Pavlawna Retèl

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)

Subject Terms: Value, Precision oncology, Comprehensive genomic profiling, Next-generation sequencing, Health technology assessment, Personalized medicine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/dfa775076b254ef5919331a8af7dd92e

Genomic profiling and expanded use of targeted anticancer drugs in solid cancers with exhausted evidence-based treatment options (PRECODE): study protocol of a prospective, non-randomized, cohort study

Authors: Karin Holmskov Hansen, Maria Bibi Lyng, Annette Raskov Kodahl, Jon Thor Asmussen, Arman Arshad, Henrik Petersen, Lotte Krogh, Sidse Ehmsen, Thomas Kielsgaard Kristensen, Henrik J. Ditzel

Source: BMC Medical Genomics, Vol 17, Iss 1, Pp 1-9 (2024)

Subject Terms: Tumor agnostic therapy, Genomic profiling, Next generation sequencing, Solid cancers, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/18375af606d74035b84b63ee801e359c

Acute Myeloid Leukemia in Older Patients: From New Biological Insights to Targeted Therapies

Authors: Pasquale Niscola, Valentina Gianfelici, Gianfranco Catalano, Marco Giovannini, Carla Mazzone, Nelida Ines Noguera, Paolo de Fabritiis

Source: Current Oncology, Vol 31, Iss 11, Pp 6632-6658 (2024)

Subject Terms: genomic profiling, targeted therapies, hypomethylating agents, venetoclax-based combinations, intensive chemotherapy, transplantation clinical trials, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/31/11/490; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/258041d01a624da3b0a4ff2280cfb46c

Clinical Outcomes of Patients with Colorectal Cancer Who Underwent Comprehensive Genomic Profiling: A Single-institution Non-comparative Prospective Observational Study

Authors: Yoshiko Mori, Okihide Suzuki, Noriko Tanabe, Aoi Sugino, Takehiro Shiraishi, Norimichi Chiyonobu, Kenichi Chikatani, Noriyasu Chika, Satoshi Hatano, Takatoshi Matsuyama, Keiichiro Ishibashi, Hideyuki Ishida

Source: Journal of the Anus, Rectum and Colon, Vol 8, Iss 4, Pp 289-297 (2024)

Subject Terms: colorectal cancer, comprehensive genomic profiling, precision oncology, high tumor mutational burden, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/jarc/8/4/8_2024-006/_pdf/-char/en; https://doaj.org/toc/2432-3853

Access URL: https://doaj.org/article/c07ff7079e574fd788b4a0358c9bde11

Impact of comprehensive genomic profiling on the diagnosis and clinical management of malignant mesenchymal tumours

Authors: Anna Beáta Csepregi, Eszter Papp, Imola Adamik, Erzsébet Csernák, Helga Engi, Zsófia Küronya, Edina Soós, Zsombor Melegh, Erika Tóth

Source: Pathology and Oncology Research, Vol 31 (2025)

Subject Terms: next generation sequencing, comprehensive genomic profiling, targeted therapy, sarcoma, mesenchymal tumours, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Pathology, RB1-214

File Description: electronic resource

Relation: https://www.por-journal.com/articles/10.3389/pore.2025.1612065/full; https://doaj.org/toc/1532-2807

Access URL: https://doaj.org/article/bc4cf7785de142e0b1374d62c5399183

Case report: Efficacy of immune checkpoint inhibitors for high tumour mutational burden malignant phyllodes tumours of the breast as revealed by comprehensive genomic profiling

Authors: Hiroo Katsuya, Haruhiko Sano, Haruna Sano, Tatsuya Mihashi, Chiho Nakashima, Keita Kai, Shinya Kimura

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: immune checkpoint inhibitor (ICI), tumour mutational burden (TMB), malignant phyllodes tumor of the breast, comprehensive genomic profiling (CGP), microsatellite instability, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1549452/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/83e9344db82e4bd189d9ec3bb16ff705

Somatic copy number deletion of chromosome 22q in papillary thyroid carcinoma

Authors: Olivia W Lee, Danielle M Karyadi, Stephen W Hartley, Weyin Zhou, Mitchell J Machiela, Shahriar A Zamani, Liudmyla Yu Zurnadzhy, John N Weinstein, Young Joo Park, Jeong-Sun Seo, Gerry A Thomas, Tetiana I Bogdanova, Mykola D Tronko, Lindsay M Morton, Stephen J Chanock

Source: European Thyroid Journal, Vol 14, Iss 1 (2025)

Subject Terms: papillary thyroid carcinoma, somatic copy number deletion, chromosome 22, genomic profiling, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://etj.bioscientifica.com/view/journals/etj/14/1/ETJ-24-0235.xml; https://doaj.org/toc/2235-0802

Access URL: https://doaj.org/article/5a437cb9a11541f69677af550dd52e10

Metastatic Thymic Mucoepidermoid Carcinoma: The Diagnostic Challenges and Role of CRTC1/MAML2 Translocation in Accurate Diagnosis and Treatment

Authors: Toshiaki Takahashi, Daniel Graham, Evan Wu

Source: Thoracic Cancer, Vol 16, Iss 2, Pp n/a-n/a (2025)

Subject Terms: comprehensive genomic profiling, mucoepidermoid carcinoma, thymic cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/53af2aefcd52425994e0bbfc0f3493b6

Uncovering somatic mosaic variants of PIK3CA-related overgrowth disorders – three cases with different clinical presentations

Authors: M. Tooming, P. Mertsina, T. Kahre, R. Teek, I. Vainumäe, S. Lilles, M. H. Wojcik, P. Ilves, K. Õunap

Source: Frontiers in Genetics, Vol 15 (2025)

Subject Terms: PIK3CA-related overgrowth syndrome, PIK3CA somatic mosaic variants, overgrowth syndrome, next-generation sequencing-based genomic profiling, PIK3CA, PIK3CA somatic mutation, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2024.1484651/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/88fbd5386ab9469c92860365e6e6aea2

Comprehensive genomic profiling of primary bladder mucinous adenocarcinoma, a rare genitourinary cancer: A case report

Authors: Shinkuro Yamamoto, Shingo Ashida, Tomoya Nao, Kaho Murakami, Ryohei Iga, Tsutomu Shimamoto, Hideo Fukuhara, Nobutaka Shimizu, Satoshi Fukata, Atsushi Kurabayashi, Takashi Karashima, Keiji Inoue

Source: Urology Case Reports, Vol 58, Iss , Pp 102892- (2025)

Subject Terms: Bladder cancer, Genomic profiling, Mucinous adenocarcinoma, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214442024002468; https://doaj.org/toc/2214-4420

Access URL: https://doaj.org/article/d29e084a09d54acfb9372ce266296dd9

Comprehensive Genomic Profiling in Non-Myeloid Hematologic Malignancies Identifies Variants That Can Alter Clinical Practice

Authors: Chenyu Lin, Katherine I. Zhou, Michelle F. Green, Bennett A. Caughey, John H. Strickler, Michael B. Datto, Matthew S. McKinney

Source: Hematology Reports, Vol 16, Iss 4, Pp 603-611 (2024)

Subject Terms: non-myeloid hematologic malignancies, comprehensive genomic profiling, actionable variants, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://www.mdpi.com/2038-8330/16/4/59; https://doaj.org/toc/2038-8330

Access URL: https://doaj.org/article/9e871b14035c478d9574989e35d84f43

Equitable Access to Genomic Molecular Testing for Australian Cancer Patients: Insights from the Victorian Precision Oncology Summit

Authors: Genevieve Dall, Karen Harris, Nonie Chan, Stephen J. Luen, Sophia Frentzas, Daphne Day, Michelle Barrett, Anna Kilgour, Mark Buzza

Source: Current Oncology, Vol 31, Iss 8, Pp 4519-4530 (2024)

Subject Terms: cancer, precision oncology, genomic testing, comprehensive genomic profiling, equitable access, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/31/8/337; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/925a83d307a64d109d6bb755f122a7ca

Exploring the impact of GSTM1 as a novel molecular determinant of survival in head and neck cancer patients of African descent

Authors: Fan Yang, Fanghui Chen, Chloe Shay, Georgia Z. Chen, Nabil F. Saba, Yong Teng

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)

Subject Terms: GSTM1, Head and neck cancer, Genomic profiling, African descent, Racial disparities, Tumor tissue microarray, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/2cd138a31c8d40ac99820dee8f89fef9

Comprehensive genomic profiling can predict response to neoadjuvant chemotherapy in triple-negative breast cancer

Authors: Monika Drobniene, Dominyka Breimelyte, Ieva Sadzeviciene, Rasa Sabaliauskaite, Ruta Barbora Valkiuniene, Raimundas Meskauskas, Daiva Dabkeviciene, Sonata Jarmalaite

Source: Breast, Vol 80, Iss , Pp 104423- (2025)

Subject Terms: Triple-negative breast cancer, Neoadjuvant chemotherapy, Comprehensive genomic profiling, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0960977625000426; https://doaj.org/toc/1532-3080

Access URL: https://doaj.org/article/0da8a3b7215e4dd18073d51871e2ce78