An Overview of the Applications of Gemfibrozil Nano-Formulation in Hyperlipidemia †.

Authors: Patel, Kiran¹, kiranpatel6770@gmail.comtejasweeni20@gmail.com, Patil, Javesh², kiranpatel6770@gmail.com, Girase, Tejasweeni¹, aayushitatiya@gmail.com, Tatiya, Aayushi¹, patil.devyani017@gmail.com, Patil, Devyani¹

Source: Materials Proceedings; 2023, Vol. 14, p45, 7p

Effect of dietary supplementation of Fructobacillus fructosus MCC 3996 on body weight, serum lipid and liver histopathology of high‑fat diet-fed swiss albino mice

Authors: Mahesh P. Patil, Jayshri Bhuktar, Jayesh J. Ahire, Ulhas K. Patil

Source: The Microbe, Vol 7, Iss , Pp 100295- (2025)

Subject Terms: Fructobacillus fructosus MCC 3996, Probiotic, Lipid profile, Weight gain, Gemfibrozil, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2950194625000639; https://doaj.org/toc/2950-1946

Access URL: https://doaj.org/article/3620d30ac8b140bb889def5b00b7521c

Gemfibrozil mitigates caspase-11-driven myocardial pyroptosis in ischemia/reperfusion injury in mice

Authors: Tetsuro Marunouchi, Mayu Kyono, Naoko Kikuchi, Kouichi Tanonaka

Source: Journal of Molecular and Cellular Cardiology Plus, Vol 12, Iss , Pp 100292- (2025)

Subject Terms: Caspase-11, Pyroptosis, Gemfibrozil, Ischemia, Reperfusion, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S277297612500011X; https://doaj.org/toc/2772-9761

Access URL: https://doaj.org/article/86dfbcfe52894c2b93c76f19724fbfdb

Advances in Chromatographic Analysis of Bioactive Compounds

Contributors: Liu, Liangliang

Subject Terms: 3,5-disubstituted hydantoins, HPLC, SFC, enantioseparation, immobilized polysaccharide-based chiral stationary phases, DMC, green solvent, Boerhavia diffusa, boeravinone B, caffeic acid, optimization, hepatoprotective activity, HPTLC, LC, MS/MS, mass spectrometry, liquid chromatography, glycosphingolipids, ceramides, gangliosides, GM3, GD3, antibacterial, cannabidiolic acid, cannabidivarinic acid, Escherichia coli, industrial hemp, antioxidant, deep eutectic solvents, flavonoids, lotus leaves, ultrasound-assisted, denaturation, peptides, separation, retention prediction, allyl chloride, gemfibrozil, genotoxic impurity, organochlorine, GC-MS/MS, protected peptides, hydrophobicity index, retention time prediction, purification, protecting groups, cyclisation, fragment condensation, adsorption, Congo red, Hibiscus cannabinus L., zinc oxide, Angelica dahurica, furocoumarin, quantitative analysis of multicomponents by single marker (QAMS), risk assessment (RA), toxic equivalency factors (TEFs), hazard index (HI), trans-β-lactam ureas, chiral chromatography, high-performance liquid chromatography (HPLC), supercritical fluid chromatography (SFC), dimethyl carbonate (DMC), immobilized polysaccharide-based CSPs, green solvents, Dioscorea alata, anticancer, phytochemical, antioxidants, electric soldering iron, rapid evaporative ionization mass spectrometry, camellia oil, adulteration, Research and information: general, Biology, life sciences

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/152697
https://mdpi.com/books/pdfview/book/9880

Six-year follow-up of a child with familial chylomicronemia syndrome: disease course and effectiveness of gemfibrozil treatment --case report and literature review

Authors: Manal Mustafa, Mira Almheiri

Source: Annals of Pediatric Endocrinology & Metabolism, Vol 29, Iss 2, Pp 130-134 (2024)

Subject Terms: hypertriglyceridemia, familial chylomicronemia syndrome, gemfibrozil, Pediatrics, RJ1-570

File Description: electronic resource

Relation: http://e-apem.org/upload/pdf/apem-2346208-104.pdf; https://doaj.org/toc/2287-1012; https://doaj.org/toc/2287-1292

Access URL: https://doaj.org/article/637a5610c1c64ae28dc5c44fe6af0225

Testing the PPAR hypothesis of tobacco use disorder in humans: A randomized trial of the impact of gemfibrozil (a partial PPARα agonist) in smokers.

Authors: Gendy, Marie N. S.^1,2, Di Ciano, Patricia¹, Kowalczyk, William J.^3,4, Barrett, Sean P.⁵, George, Tony P.^6,7,8,9, Heishman, Stephen³, Le Foll, Bernard^{1,2,6,7,8,10,11} bernard.lefoll@camh.ca

Source: PLoS ONE. 9/27/2018, Vol. 13 Issue 9, p1-14. 14p.

Subject Terms: *GEMFIBROZIL, *PLACEBOS, *DRUG efficacy, *SMOKING cessation, *THERAPEUTICS, TOBACCO & health

Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders.

Authors: Kyeongsoon Kim¹, Kleinman, Hynda K.^2,3 hyndakk@aol.com, Hahn-Jun Lee², Pahan, Kalipada⁴, Kim, Kyeongsoon¹ (AUTHOR), Lee, Hahn-Jun² (AUTHOR)

Source: Orphanet Journal of Rare Diseases. 6/17/2017, Vol. 12, p1-9. 9p.

Subject Terms: *GEMFIBROZIL, *NEURONAL ceroid-lipofuscinosis, *TREATMENT of lipidoses, *MEDICATION safety, *DRUG efficacy, *THERAPEUTICS

Amelioration of experimental autoimmune encephalomyelitis by gemfibrozil in mice via PPARβ/δ: implications for multiple sclerosis

Authors: Susanta Mondal, Monica Sheinin, Suresh B. Rangasamy, Kalipada Pahan

Source: Frontiers in Cellular Neuroscience, Vol 18 (2024)

Subject Terms: gemfibrozil, EAE, MS, blood–brain barrier, neuroinflammation, PPAR, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fncel.2024.1375531/full; https://doaj.org/toc/1662-5102

Access URL: https://doaj.org/article/b8c0de87998f42d3976c3fa4f52fb65f

PPARα-dependent increase of mouse urine output by gemfibrozil and fenofibrate.

Authors: Song, Danjun¹, Luo, Min¹, Dai, Manyun¹, Bu, Shizhong¹, Wang, Weihua², Zhang, Burong², Gonzalez, Frank J.³, Liu, Aiming¹

Source: Canadian Journal of Physiology & Pharmacology. 2017, Vol. 95 Issue 2, p199-205. 7p.

Subject Terms: *GEMFIBROZIL, *FENOFIBRATE, *DYSLIPIDEMIA, *METABOLIC syndrome, *URINALYSIS, *THERAPEUTICS

Pharmacological Effects of Gemfibrozil on Some Isolated Smooth Muscle Preparations Of Experimental Animals.

Authors: El Makkawy, Fatma Sabry¹, Ezzo, Azza Mohammed¹, El-Aty Ouda, Enass Abd¹, El-Said Mahmoud Al-Kassas, Azza¹

Source: Egyptian Journal of Hospital Medicine. Jan2017, Vol. 66, p1-17. 17p.

Subject Terms: *GEMFIBROZIL, *DRUG efficacy, *SMOOTH muscle, *DYSLIPIDEMIA, *PEROXISOME proliferator-activated receptors, *DRUG dosage, *THERAPEUTICS

Neonatal hyperlipidemia with pancreatitis: Novel gene mutation of lipoprotein lipase.

Authors: Shah, M¹, Roshan, R², Desai, R¹, Kadam, S¹

Source: Journal of Postgraduate Medicine. Oct-Dec2018, Vol. 64 Issue 4, p247-249. 3p.

Subject Terms: *LYSOSOMAL storage diseases, *GEMFIBROZIL, *DIET, *ESTERASES, *FEVER, *HYPERLIPIDEMIA, *LIPIDS, *GENETIC mutation, *NEUROLOGIC manifestations of general diseases, *OPHTHALMOSCOPY, *PANCREATITIS, *RETINAL diseases, *TRIGLYCERIDES, *VOMITING, *GENETIC testing, *SEVERITY of illness index, *DISEASE complications, *CHILDREN, *GENETICS, *THERAPEUTICS

Synthesis and identification of magnetic nickel oxide nanoparticles for the magnetic solid phase extraction of gemfibrozil and its determination by UV-Vis spectrometer.

Authors: Narges Salehi, ali moghimi

Source: شیمی کاربردی روز, Vol 18, Iss 68, Pp 323-342 (2023)

Subject Terms: modification of nickel oxide, gemfibrozil, magnetic solid phase extraction, adsorption, Chemistry, QD1-999

File Description: electronic resource

Relation: https://chemistry.semnan.ac.ir/article_8185_e9d4a059d82fdbc4fd01c78aa6f5e032.pdf; https://doaj.org/toc/2981-2437

Access URL: https://doaj.org/article/3611be81811b4c79a2a93b98e06a34e8

The fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies.

Authors: Sharina, I G¹, Sobolevsky, M¹, Papakyriakou, A², Rukoyatkina, N^3,4, Spyroulias, G A⁵, Gambaryan, S^3,4, Martin, E¹

Source: British Journal of Pharmacology. May2015, Vol. 172 Issue 9, p2316-2329. 14p.

Subject Terms: *GEMFIBROZIL, *GUANYLATE cyclase, *NITRIC oxide, *DYSLIPIDEMIA, *PEROXISOME proliferator-activated receptors, *LIPID metabolism

The Effects of Gemfibrozil and Ovariectomy on the Peroxisome Proliferator Activated Receptors (PPARs) in Mice with Experimentally Induced Obesity.

Alternate Title: Deneysel Obezite Oluşturulan Farelerde Ovarioektomi Operasyonu ve Gemfibrozilin Peroksizom Proliferatörleri ile Aktive Olan Reseptörler (PPARs) ve Obezite Üzerine Etkilerinin Araştırılması.

Authors: TUNCA, Recai¹ rtunca26@hotmail.com, DEVRIM, Alparslan Kadir², SOZMEN, Mahmut³, DAG, Serpil⁴, GUNGOR, Orsan⁵, IPEK, Emrah¹

Source: Kafkas Universitesi Veteriner Fakultesi Dergisi. Sep/Oct2013, Vol. 19 Issue 5, p783-792. 10p.

Subject Terms: *OVARIECTOMY, *GEMFIBROZIL, *PEROXISOME proliferator-activated receptors, *LABORATORY mice, *FATTY degeneration, *IMMUNOHISTOCHEMISTRY, *BLOOD cholesterol

Determination of Gemfibrozil in Drug Matrix and Human Biological Fluid by Dispersive Liquid-Liquid Microextraction with High Performance Liquid Chromatography.

Authors: Panahi, Homayon Ahmad¹ h.ahmadpanahi@iauctb.ac.ir, Feizbakhsh, Alireza¹, Karimpour, Morteza¹, Moniri, Elham²

Source: Journal of Food & Drug Analysis. Mar2013, Vol. 21 Issue 1, p109-114. 6p. 1 Diagram, 3 Charts, 6 Graphs.

Subject Terms: *GEMFIBROZIL, *ANTILIPEMIC agents, *HIGH performance liquid chromatography, *MOLECULAR structure, *SOLVENTS, *SPECTROPHOTOMETRY, *DATA analysis software, *DESCRIPTIVE statistics, *IN vitro studies

Effects of Gemfibrozil and L-carnitine on PON1 Activity, Oxidative/Anti-Oxidative Parameters and Hepatosteatosis in Rabbits Feed With Fat-Rich Diet.

Alternate Title: Yüksek Yağlı Diyetle Beslenen Tavşanlarda Gemfibrozil ve L-carnitine Uygulamalarının PON1 Aktivitesi, Oksidatif/Anti- Oksidatif Parametreleri ve Hepatosteatozis Üzerine Etkileri.

Authors: Selek, Sahabettin¹ sahselek@gmail.com, Karapehlivan, Mahmut², Citil, Mehmet³, Tunca, Recai⁴, Uzlu, Erdogan³, Erdogan, Hidayet Metin³

Source: Kafkas Universitesi Veteriner Fakultesi Dergisi. 2011, Vol. 17 Issue 2, p183-190. 8p.

Subject Terms: *RABBITS, *GEMFIBROZIL, *PARAOXONASE, *CARNITINE, *SERUM, *LIPOPROTEINS, *CHOLESTEROL, *ANIMAL health

Geographic Terms: NEW Zealand

Acute pancreatitis secondary to tamoxifen-associated hypertriglyceridemia: A clinical update.

Authors: Goraya, Muhammad Hassan Naeem, Abbasi, Ehsan ul Haq, Amin, Muhammad Kashif, Inayat, Faisal, Ashraf, Muhammad Junaid, Qayyum, Mahrukh, Hussain, Nadeem, Nawaz, Gul, Zaman, Muhammad Adnan, Malik, Adnan

Source: Journal of Oncology Pharmacy Practice; Jan2023, Vol. 29 Issue 1, p218-225, 8p

Subject Terms: PANCREATITIS diagnosis, DRUG therapy for hyperlipidemia, PANCREATITIS treatment, LIPASES, TRIGLYCERIDES, INTRAVENOUS therapy, GENERIC drug substitution, LETROZOLE, GEMFIBROZIL, DIFFERENTIAL diagnosis, HYPERLIPIDEMIA, INSULIN, TAMOXIFEN, PANCREATITIS, ABDOMINAL pain, BREAST tumors, DISEASE complications, SYMPTOMS

Combined gemfibrozil (peroxisome proliferator-activated receptor alpha agonist) with reduced steroid dose gives a similar management picture as the full steroid dose in a rat adjuvant-induced arthritis model.

Authors: Ashour, Hend¹ hend.a.hassan@kasralainy.edu.eg, Ahmed Rashed, Laila², Mahmoud El-Sebaie, Mohamed², Mohammed Sabry, Marwa³, Abdelmohsen, Manal Ali³, Eissa, Mervat⁴

Source: Modern Rheumatology. Jul2019, Vol. 29 Issue 4, p602-611. 10p.

Subject Terms: *GEMFIBROZIL, *PREDNISOLONE, *ADJUVANT arthritis, *RHEUMATOID arthritis, *STEROIDS

Parental gemfibrozil exposure impacts zebrafish F1 offspring, but not subsequent generations.

Authors: Fraz, Shamaila¹ (AUTHOR) shumailafaraz@gmail.com, Lee, Abigail H.¹ (AUTHOR) abigail.ha.lee@gmail.com, Pollard, Simon¹ (AUTHOR) pollarsm@gmail.com, Srinivasan, Krishna¹ (AUTHOR) srinivk@mcmaster.ca, Vermani, Abhilasha¹ (AUTHOR) avermani05@gmail.com, Wilson, Joanna Y.¹ (AUTHOR) joanna.wilson@mcmaster.ca

Source: Aquatic Toxicology. Jul2019, Vol. 212, p194-204. 11p.

Subject Terms: *Endocrine disruptors, *Fresh water, *Water pollution, Fish reproduction, Gemfibrozil, Zebra danio, Testosterone

Effects of gemfibrozil on sex hormones and reproduction related performances of Oryzias latipes following long-term (155 d) and short-term (21 d) exposure.

Authors: Lee, Gowoon¹, Lee, Sangwoo^1,2, Ha, Nayoung¹, Kho, Younglim³, Park, Kyunghwa⁴, Kim, Pilje⁴, Ahn, Byeongwoo⁵, Kim, Sunmi¹, Choi, Kyungho¹ kyungho@snu.ac.kr

Source: Ecotoxicology & Environmental Safety. May2019, Vol. 173, p174-181. 8p.

Subject Terms: *Freshwater ecology, Gemfibrozil, Sex hormones, Oryzias latipes, Gene expression