Bioinformatics analysis of coronary microvascular dysfunction in rats based on single-cell RNA sequencing

Authors: Hao Li, Yiding Jia, Zelin Chen, Luqun Yang, Lin Ni, Yuchen Cao, Rong Fan, Zitong Yuan, Kaiyi Zhu, Zhijun Zhang, Lin Zuo, Ping Wu, Yuping Gao, Yuanyuan Lin

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-13 (2025)

Subject Terms: Coronary microvascular dysfunction, Single-cell RNA sequencing, Bioinformatics analysis, Endothelial cells, Endothelial-to-mesenchymal transition, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/25baf8228a4f47eb822bf220088f44e3

The role of epithelial-mesenchymal transition in pulmonary fibrosis: lessons from idiopathic pulmonary fibrosis and COVID-19

Authors: Reyhaneh Niayesh-Mehr, Mojtaba Kalantar, Giulio Bontempi, Claudia Montaldo, Saeedeh Ebrahimi, Abdolamir Allameh, Ghader Babaei, Faezeh Seif, Raffaele Strippoli

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)

Subject Terms: Idiopathic pulmonary fibrosis (IPF), COVID-19, Pulmonary fibrosis (PF), Epithelial to mesenchymal transition (EMT), Endothelial to mesenchymal transition (EndMT), Mesothelial to mesenchymal transition (MMT), Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/eb2fbefc3d8f4831a55341f22cd70047

Endothelial KLF11 is a novel protector against diabetic atherosclerosis

Authors: Guizhen Zhao, Yang Zhao, Wenying Liang, Haocheng Lu, Hongyu Liu, Yongjie Deng, Tianqing Zhu, Yanhong Guo, Lin Chang, Minerva T. Garcia-Barrio, Y. Eugene Chen, Jifeng Zhang

Source: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-21 (2024)

Subject Terms: Atherosclerosis, Diabetes, Endothelial cell, KLF11, Endothelial-to-mesenchymal transition (EndMT), Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/5ceec1f643e142d68958d73f93f18010

Assessing personalized molecular portraits underlying endothelial-to-mesenchymal transition within pulmonary arterial hypertension

Authors: Ruhao Wu, Ge Zhang, Mingzhou Guo, Yue Li, Lu Qin, Tianci Jiang, Pengfei Li, Yu Wang, Ke Wang, Yize Liu, Zhiqiu He, Zhe Cheng

Source: Molecular Medicine, Vol 30, Iss 1, Pp 1-17 (2024)

Subject Terms: Endothelial-to-mesenchymal transition, Pulmonary arterial hypertension, Machine learning, Biomarker, Molecular signature, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/9a39d49464f742fa95c4fea841bd7cff

siLOXL2 Inhibits Endothelial Inflammatory Response and EndMT Induced by ox-LDL

Authors: Jing Ma, Jia Ling, Rui Tong, Jiefen Guo, Zhongsheng Zhu

Source: Cerebrovascular Diseases Extra, Vol 14, Iss 1, Pp 165-176 (2024)

Subject Terms: lysyl oxidase-like 2, inflammation, human umbilical vein endothelial cells, oxidized low-density lipoprotein, endothelial-to-mesenchymal transition, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://beta.karger.com/Article/FullText/541906; https://doaj.org/toc/1664-5456

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Secretomes From Non‐Small Cell Lung Cancer Cells Induce Endothelial Plasticity Through a Partial Endothelial‐to‐Mesenchymal Transition

Authors: Clara Bourreau, Emilie Navarro, Marine Cotinat, Morgane Krejbich, François Guillonneau, Catherine Guette, Alice Boissard, Cécile Henry, Isabelle Corre, Lucas Treps, Nicolas Clere

Source: Cancer Medicine, Vol 14, Iss 5, Pp n/a-n/a (2025)

Subject Terms: EndMT, endothelial cell plasticity, endothelial‐to‐mesenchymal transition, non‐small cell lung cancer, secretome, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/18f05edb78c648f7b5385badf1b3ea3f

Cellular cross-talk drives mesenchymal transdifferentiation in diabetic kidney disease

Authors: Arunita Chatterjee, Jacqueline Tumarin, Sharma Prabhakar

Source: Frontiers in Medicine, Vol 11 (2025)

Subject Terms: diabetes mellitus, kidney disease, cellular cross-talk, EMT, endothelial-to-mesenchymal transition, SGLT-2 inhibitors, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1499473/full; https://doaj.org/toc/2296-858X

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Oxidative stress mediates glycidol-induced endothelial injury and its protection by 6-C-(E-2-fluorostyryl)naringenin

Authors: Yue Zhou, Hui Xu, Ka-Wing Cheng, Feng Chen, Qian Zhou, Mingfu Wang

Source: Food Science and Human Wellness, Vol 13, Iss 5, Pp 2584-2594 (2024)

Subject Terms: glycidol, endothelial cells, 6-c-(e-2-fluorostyryl)naringenin, oxidative stress, endothelial-to-mesenchymal transition, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.sciopen.com/article/10.26599/FSHW.2022.9250207; https://doaj.org/toc/2097-0765; https://doaj.org/toc/2213-4530

Access URL: https://doaj.org/article/7ca0c2c412f3479eb3a6084aeb557eaa

ASF1A-dependent P300-mediated histone H3 lysine 18 lactylation promotes atherosclerosis by regulating EndMT

Authors: Mengdie Dong, Yunjia Zhang, Minghong Chen, Yongkang Tan, Jiao Min, Xian He, Fuhao Liu, Jiaming Gu, Hong Jiang, Longbin Zheng, Jiajing Chen, Quanwen Yin, Xuesong Li, Xiang Chen, Yongfeng Shao, Yong Ji, Hongshan Chen

Source: Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3027-3048 (2024)

Subject Terms: Histone lactylation, Atherosclerosis, Endothelial-to-mesenchymal transition, ASF1A, SNAI1, Endothelial dysfunction, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383524000893; https://doaj.org/toc/2211-3835

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circZNF532 promotes endothelial-to-mesenchymal transition in diabetic retinopathy by recruiting TAF15 to stabilize PIK3CD

Authors: Xiao-Lin Fu, Fu-Tao He, Mo-Han Li, Chun-Yan Fu, Jian-Zhi Chen

Source: Endocrine Journal, Vol 71, Iss 7, Pp 675-686 (2024)

Subject Terms: diabetic retinopathy (dr), human retinal microvascular endothelial cells (hrmecs), endothelial-to-mesenchymal transition (endmt), circrna zinc finger protein 532 (circznf532), phosphoinositide-3 kinase catalytic subunit δ (pik3cd), Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/endocrj/71/7/71_EJ23-0683/_html/-char/en; https://doaj.org/toc/1348-4540

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LncRNAH19 acts as a ceRNA of let-7 g to facilitate endothelial-to-mesenchymal transition in hypoxic pulmonary hypertension via regulating TGF-β signalling pathway

Authors: Xin Yu, Jiabing Huang, Xu Liu, Juan Li, Miao Yu, Minghui Li, Yuliang Xie, Ye Li, Junyu Qiu, Zhou Xu, Tiantian Zhu, Weifang Zhang

Source: Respiratory Research, Vol 25, Iss 1, Pp 1-15 (2024)

Subject Terms: Hypoxic pulmonary hypertension, lncRNA-H19, Endothelial-to-mesenchymal transition, microRNA-let-7 g, TGFβR1, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/fdd37253054f4882a9007b15ee26ef07

Inhalation of hydrogen gas protects against mitomycin-induced pulmonary veno-occlusive disease

Authors: Chenting Zhang, Yue Xing, Xuefen Wu, Qian Jiang, Xiaoyun Luo, Wei He, Shiyun Liu, Wenju Lu, Jian Wang

Source: Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)

Subject Terms: Hydrogen gas, Pulmonary veno-occlusive disease, Antioxidant, Anti-inflammatory, Endothelial-to-mesenchymal transition, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/bcb4ec9e23ed4b9090c87538a4569548

Tianlong Kechuanling decoction attenuates pulmonary hypertension by inhibiting endothelial-to-mesenchymal transition

Authors: Gong, Jing ^a, Li, Huihua ^a, Cui, Xiaoqing ^a, Yan, Yuling ^a, Yu, Qinghe ^a, Ding, Qi ^{b, ⁎⁎⁎}, Shi, Yuanyuan ^{b, ⁎⁎}, Wang, Peng ^{a, ⁎}

Source: In Journal of Ethnopharmacology 13 March 2025 343

Role of Xuefu Zhuyu decoction in improving pulmonary vascular remodeling by inhibiting endothelial-to-mesenchymal transition

Authors: Zeng, Zuomei ^a, Wang, Xinyue ^a, Wang, Hongjuan ^b, Tian, Leiyu ^a, Cui, Lidan ^a, Guo, Jian ^{a, ∗}, Chen, Yucai ^{a, ⁎}

Source: In Vascular Pharmacology March 2025 158

METTL3-mediated m6A modification of EGR1 mRNA promotes T2DM vasculopathy

Authors: Tao, Meng ^{a, b, 1}, Shan, Li ^{a, 1}, Zhang, Wei ^b, Wei, LiangBing ^a, Guo, MingFei ^{c, d}, Fang, ZhaoHui ^{a, e}, Zhao, JinDong ^{a, e}, Gao, JiaRong ^{a, ⁎}

Source: In Cellular Signalling March 2025 127

Rhythmic forces shaping the zebrafish cardiac system

Authors: Fukui, Hajime ^{1, 2}, Chow, Renee Wei-Yan ³, Yap, Choon Hwai ⁴, Vermot, Julien ^{4, ∗}

Source: In Trends in Cell Biology February 2025 35(2):166-176

USP25 ameliorates vascular remodeling by deubiquitinating FOXO3 and promoting autophagic degradation of FOXO3

Authors: Chen, Yanghao ^{a, b, †}, Ye, Bozhi ^{a, b, †}, Xu, Diyun ^{a, b, †}, Lin, Wante ^{a, b}, Fang, Zimin ^{a, b}, Qu, Xuefeng ^c, Han, Xue ^c, Luo, Wu ^b, Chen, Chen ^a, Huang, Weijian ^a, Zhou, Hao ^a, Wu, Gaojun ^a, Wang, Yi ^{b, d, ⁎}, Liang, Guang ^{a, b, c, ⁎}

Source: In Acta Pharmaceutica Sinica B July 2024

PKM2‐Driven Lactate Overproduction Triggers Endothelial‐To‐Mesenchymal Transition in Ischemic Flap via Mediating TWIST1 Lactylation

Authors: Yining Xu, Xianhui Ma, Weiyu Ni, Lin Zheng, Zhongnan Lin, Yingying Lai, Ningning Yang, Zhanqiu Dai, Teng Yao, Zeyang Chen, Lifeng Shen, Haitao Wang, Long Wang, Yizheng Wu, Weiyang Gao

Source: Advanced Science, Vol 11, Iss 47, Pp n/a-n/a (2024)

Subject Terms: endothelial‐to‐mesenchymal transition, lactate, lactylation, Pyruvate kinase M2, random‐pattern skin flap, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/19f8e773f3014b079786577b4ec6bee4

Promotor Hypomethylation Mediated Upregulation of VCAN Targets Twist1 to Promote EndMT in Hypoxia‐Induced Pulmonary Hypertension

Authors: Jinyan Yu, Shanchao Hong, Lingjia Yang, Shugao Ye, Zhen Yu, Zheming Zhang, Ziteng Wang, Shulun Huang, Yuan Chen, Tao Bian, Yan Wu

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 23 (2024)

Subject Terms: DNA methylation, endothelial‐to‐mesenchymal transition, hypoxia‐induced pulmonary hypertension, Twist1, versican, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/1c3fd786d0ae4f5997c7362798e1d55d

Perspective: Pathological transdifferentiation—a novel therapeutic target for cardiovascular diseases and chronic inflammation

Authors: William Y. Yang, Mohammed Ben Issa, Fatma Saaoud, Keman Xu, Ying Shao, Yifan Lu, Waleska Dornas, Ramon Cueto, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

Source: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

Subject Terms: pathological transdifferentiation, chronic inflammation, cardiovascular diseases, epithelial to mesenchymal transition, endothelial to mesenchymal transition, vascular smooth muscle to mesenchymal transition, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2024.1500775/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/6c44708d21ae49d1a2be22238d6b67b6