Dexrazoxane prevents vascular toxicity in doxorubicin-treated mice

Authors: Dustin N. Krüger, Matthias Bosman, Emeline M. Van Craenenbroeck, Guido R. Y. De Meyer, Constantijn Franssen, Pieter-Jan Guns

Source: Cardio-Oncology, Vol 10, Iss 1, Pp 1-11 (2024)

Subject Terms: Doxorubicin, Dexrazoxane, Vascular toxicity, Endothelial cell dysfunction, SERPINA3, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/56a98f05017b45b4b30d87d48e86a2eb

Oxidative Stress and Its Biomarkers in Cardiovascular Diseases

Authors: Julija Valaitienė, Agnė Laučytė-Cibulskienė

Source: Artery Research, Vol 30, Iss 1, Pp 1-12 (2024)

Subject Terms: Biomarkers, Cardiovascular diseases, Endothelial cell dysfunction, Inflammation, Oxidative stress, Reactive oxygen species, Specialties of internal medicine, RC581-951, Diseases of the circulatory (Cardiovascular) system, RC666-701

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Relation: https://doaj.org/toc/1876-4401

Access URL: https://doaj.org/article/70f0769e6b3846f2bc241ef6924e35c4

VAMP8 as a biomarker and potential therapeutic target for endothelial cell dysfunction in atherosclerosis

Authors: Yang, Luqun, Guan, Xin, Cheng, Jiangwei, Ni, Lin, Yao, Huijing, Gao, Yuping, Zhu, Kaiyi, Shi, Xiushan, Li, Bingjie, Lin, Yuanyuan ^⁎

Source: In Gene 20 March 2025 942

Endothelial SHP-1 regulates diabetes-induced abnormal collateral vessel formation and endothelial cell senescence

Authors: Nadeau, Alexandre ^a, Ouellet, Marike ^a, Béland, Raphaël ^a, Mercier, Clément ^a, Robillard, Stéphanie ^a, Lizotte, Farah ^a, Despatis, Marc-Antoine ^b, Bentzinger, C. Florian ^{a, c}, Geraldes, Pedro ^{a, d, ⁎}

Source: In Journal of Molecular and Cellular Cardiology May 2025 202:50-63

Endothelial cell dysfunction and targeted therapeutic drugs in sepsis

Authors: Kunwei Chen, Dongdong Wang, Minyue Qian, Mengcao Weng, Zhongteng Lu, Kai Zhang, Yue Jin

Source: Heliyon, Vol 10, Iss 13, Pp e33340- (2024)

Subject Terms: Sepsis, Vascular endothelial cells, Endothelial cell dysfunction, Targeted therapeutic drugs, Science (General), Q1-390, Social sciences (General), H1-99

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Relation: http://www.sciencedirect.com/science/article/pii/S240584402409371X; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/a38585b530b0449992e7f5ec37092288

Diagnostic and prognostic potential of long non-coding RNA NORAD in patients with acute deep vein thrombosis and its role in endothelial cell function

Authors: Kun Zhou, Na Li, Jia Qi, Pingping Tu, Yan Yang, Hui Duan

Source: Thrombosis Journal, Vol 22, Iss 1, Pp 1-13 (2024)

Subject Terms: NORAD/miR-93-5p axis, Deep venous thrombosis, Clinical value, Endothelial cell dysfunction, Diseases of the blood and blood-forming organs, RC633-647.5

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Relation: https://doaj.org/toc/1477-9560

Access URL: https://doaj.org/article/a41f70f1fb2444fb949bd50ad794bc2a

Novel Morphological Profiling Assay Connects ex Vivo Endothelial Cell Responses to Disease Severity in Liver Cirrhosis

Authors: Rudmer J. Postma, Annelotte G.C. Broekhoven, Hein W. Verspaget, Hetty de Boer, Thomas Hankemeier, Minneke J. Coenraad, Vincent van Duinen, Anton Jan van Zonneveld

Source: Gastro Hep Advances, Vol 3, Iss 2, Pp 238-249 (2024)

Subject Terms: Endothelial Cell Dysfunction, Liver Cirrhosis, Morphological Profiling, Mitochondria, Diseases of the digestive system. Gastroenterology, RC799-869

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Relation: http://www.sciencedirect.com/science/article/pii/S2772572323001656; https://doaj.org/toc/2772-5723

Access URL: https://doaj.org/article/742f63ba3443492ebb728d8cb78e9eb4

Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches

Contributors: Jeon, Byeong Hwa

Subject Terms: endothelial cells, oxidative stress, inflammageing, endothelial dysfunction, aldehyde dehydrogenase-2, cardiovascular disease, neurovascular disease, vascular inflammation, APE1/Ref-1, cardiovascular diseases, subcellular localization, serological biomarkers, atherosclerosis, aerobic exercise, PCSK9, LOX-1, insulin resistance, macrophage polarity, serum γ-glutamyltransferase, essential hypertension, cardiovascular risk factors, angiogenesis, nargenicin A1, compound 9, VEGF, VEGFR2, HIF-1α, electronegative low-density lipoprotein, LDL(–), L5 LDL, oxidized LDL, oxLDL, ADMA, arginine, arginine paradox, BH4, blood pressure, COVID-19, dietary supplements, endothelium, eNOS uncoupling, heart failure, hypertension, L-arginine, myocardial infarction, NADPH, nitric oxide, peripheral artery disease, ApoE knockout mouse, atorvastatin, VCAM-1, galectin-3, neutrophil/lymphocyte ratio, electronegative LDL, LDL(−), lectin-like oxLDL receptor-1, dyslipidemia, chronic venous insufficiency, prolyl oligopeptidase (POP), inflammation, endothelial disfunction, lung disease, endothelial to mesenchymal transition, pulmonary hypertension, pulmonary fibrosis, metformin, diabetes, CV risk, hyperglycemia, glycated lipoproteins, glycated LDL, glycated HDL, endothelial cell dysfunction, molecular mechanisms, epigenetic factors, therapeutic approaches, vasoactive factors, EndoMT, TGF-β, epigenetics, endothelial cell, glycolysis, metabolism, pathological angiogenesis, tumor microenvironment, MRI (magnetic resonance imaging), high-fat diets, plaque burden, low-level laser therapy, phototherapy, vascular disease, healing, ischemia, vascular calcification, chronic kidney disease, CKD, uremic toxins, hyperphosphatemia, vascular smooth muscle cells, VSMCs, macrophages, Technology: general issues, Biotechnology

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Access URL: https://directory.doabooks.org/handle/20.500.12854/81021
https://mdpi.com/books/pdfview/book/5363

Ginsenoside Rh1 protects human endothelial cells against lipopolysaccharide-induced inflammatory injury through inhibiting TLR2/4-mediated STAT3, NF-κB, and ER stress signaling pathways

Authors: Jin, Yujin, Nguyen, Thuy Le Lam, Myung, Chang-Seon, Heo, Kyung-Sun ^⁎

Source: In Life Sciences 15 November 2022 309

LncRNA HOXA11‐AS promotes vascular endothelial cell injury in atherosclerosis by regulating the miR‐515‐5p/ROCK1 axis

Authors: Feng Gao, Xiao‐Chen Wang, Zhi‐Dan Luo, Guang‐Quan Hu, Meng‐Qing Ma, Yi Liang, Bang‐Long Xu, Xian‐He Lin

Source: ESC Heart Failure, Vol 9, Iss 4, Pp 2259-2271 (2022)

Subject Terms: LncRNA HOXA11‐AS, Atherosclerosis, miR‐515‐5p, ROCK1, Vascular endothelial cell dysfunction, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/c8de64d1865d4af894a3332d01aa8b8a

Hyperphosphatemia and its relationship with blood pressure, vasoconstriction, and endothelial cell dysfunction in hypertensive hemodialysis patients

Authors: Jinwoo Jung, Haekyung Jeon-Slaughter, Hang Nguyen, Jiten Patel, Kamalanathan K. Sambandam, Shani Shastri, Peter Noel Van Buren

Source: BMC Nephrology, Vol 23, Iss 1, Pp 1-8 (2022)

Subject Terms: Phosphate, Hemodialysis, Endothelial cell dysfunction, Mineral bone disease, Vasoconstriction, Diseases of the genitourinary system. Urology, RC870-923

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Relation: https://doaj.org/toc/1471-2369

Access URL: https://doaj.org/article/2e02c4f93103480e887ea9a39965cbc2

Oridonin attenuates low shear stress-induced endothelial cell dysfunction and oxidative stress by activating the nuclear factor erythroid 2-related factor 2 pathway

Authors: Zhipeng Chen, Heqian Liu, Xiaoqi Zhao, Subinur Mamateli, Cheng Liu, Lei Wang, Jing Yu, Yutong Liu, Jing Cai, Tong Qiao

Source: BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-14 (2022)

Subject Terms: Oridonin, Low shear stress, Atherosclerosis, Endothelial cell dysfunction, Oxidative stress, Zebrafish, Other systems of medicine, RZ201-999

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Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/ee4fc4870f344e9faf79af37f1022ca7

Circulating extracellular vesicles from patients with traumatic brain injury induce cerebrovascular endothelial dysfunction

Authors: Lei Li, Fanjian Li, Xuesong Bai, Haoran Jia, Cong Wang, Peng Li, Qiaoling Zhang, Siyu Guan, Ruilong Peng, Shu Zhang, Jing-fei Dong, Jianning Zhang, Xin Xu

Source: Pharmacological Research, Vol 192, Iss , Pp 106791- (2023)

Subject Terms: Traumatic brain injury, Endothelial cell dysfunction, Extracellular vesicles, High mobility group box 1, Von Willebrand factor, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S1043661823001470; https://doaj.org/toc/1096-1186

Access URL: https://doaj.org/article/b0c00c8e0bd54897ba380d6e5cc05222

A novel OSA-related model of intermittent hypoxia in endothelial cells under flow reveals pronounced inflammatory pathway activation

Authors: Martin B. Müller, Clemens Stihl, Annika Schmid, Simon Hirschberger, Rea Mitsigiorgi, Martin Holzer, Martin Patscheider, Bernhard G. Weiss, Christoph Reichel, Max Hübner, Bernd Uhl

Source: Frontiers in Physiology, Vol 14 (2023)

Subject Terms: obstructive sleep apnea, intermittent hypoxia (IH), endothelial cell dysfunction, cell culture models, culture under flow, inflammation, Physiology, QP1-981

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Relation: https://www.frontiersin.org/articles/10.3389/fphys.2023.1108966/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/4a9b5118629344b39a875644f6afa592

Circulatory metabolites trigger ex vivo arterial endothelial cell dysfunction in population chronically exposed to diesel exhaust

Authors: Wenting Cheng, Huanhuan Pang, Matthew J. Campen, Jianzhong Zhang, Yanting Li, Jinling Gao, Dunqiang Ren, Xiaoya Ji, Nathaniel Rothman, Qing Lan, Yuxin Zheng, Shuguang Leng, Zeping Hu, Jinglong Tang

Source: Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-14 (2022)

Subject Terms: Diesel exhaust, Endothelial cell dysfunction, Circulatory metabolites, Cardiovascular disease risk, Toxicology. Poisons, RA1190-1270, Industrial hygiene. Industrial welfare, HD7260-7780.8

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Relation: https://doaj.org/toc/1743-8977

Access URL: https://doaj.org/article/a74fe31706334d50bb71590b1409744b

Reduced circulating BMP9 and pBMP10 in hospitalized COVID‐19 patients

Authors: Benjamin J. Dunmore, Paul D. Upton, Kate Auckland, Romit J. Samanta, CITIID‐NIHR BioResource COVID‐19 Collaboration, The EpiCov Database, Paul A. Lyons, Kenneth G. C. Smith, Stefan Gräf, Charlotte Summers, Nicholas W. Morrell

Source: Pulmonary Circulation, Vol 13, Iss 1, Pp n/a-n/a (2023)

Subject Terms: BMPs, endothelial cell dysfunction, viral infections and pathogenesis, Diseases of the circulatory (Cardiovascular) system, RC666-701, Diseases of the respiratory system, RC705-779

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Relation: https://doaj.org/toc/2045-8940

Access URL: https://doaj.org/article/6cf8c4a70f85404985b5af34ee39b021

Neutrophil, neutrophil extracellular traps and endothelial cell dysfunction in sepsis

Authors: Hao Zhang, Yanghanzhao Wang, Mengdi Qu, Wenqian Li, Dan Wu, Juan P. Cata, Changhong Miao

Source: Clinical and Translational Medicine, Vol 13, Iss 1, Pp n/a-n/a (2023)

Subject Terms: endothelial cell dysfunction, neutrophil, neutrophil extracellular traps, sepsis, Medicine (General), R5-920

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Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/f9c2c455a42f4154a5dde728863f3b1c

Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease

Authors: Kyoung Woon Kim, Yoo Jin Shin, Bo-Mi Kim, Sheng Cui, Eun Jeong Ko, Sun Woo Lim, Chul Woo Yang, Byung Ha Chung

Source: Kidney Research and Clinical Practice, Vol 40, Iss 4, Pp 698-711 (2021)

Subject Terms: cd31, endothelial cell dysfunction, end-stage renal disease, pluripotent stem cell, microarray, Internal medicine, RC31-1245, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.krcp-ksn.org/upload/pdf/j-krcp-20-252.pdf; https://doaj.org/toc/2211-9132; https://doaj.org/toc/2211-9140

Access URL: https://doaj.org/article/52bb8878333c48e4a939010da92aae09

Liver injury in COVID-19 and IL-6 trans-signaling-induced endotheliopathy

Authors: McConnell, Matthew J. ^{1, †}, Kawaguchi, Nao ^{1, †}, Kondo, Reiichiro ^{1, 2}, Sonzogni, Aurelio ³, Licini, Lisa ³, Valle, Clarissa ^{4, 5}, Bonaffini, Pietro A. ^{4, 5}, Sironi, Sandro ^{4, 5}, Alessio, Maria Grazia ⁶, Previtali, Giulia ⁶, Seghezzi, Michela ⁶, Zhang, Xuchen ⁷, Lee, Alfred I. ⁸, Pine, Alexander B. ⁸, Chun, Hyung J. ⁹, Zhang, Xinbo ¹⁰, Fernandez-Hernando, Carlos ^{7, 10}, Qing, Hua ¹¹, Wang, Andrew ¹¹, Price, Christina ¹¹, Sun, Zhaoli ¹², Utsumi, Teruo ¹, Hwa, John ⁹, Strazzabosco, Mario ¹, Iwakiri, Yasuko ^{1, ∗}

Source: In Journal of Hepatology September 2021 75(3):647-658

Endothelial cell dysfunction: Implications for the pathogenesis of peripheral artery disease

Authors: Mary M. Kavurma, Christina Bursill, Christopher P. Stanley, Freda Passam, Siân P. Cartland, Sanjay Patel, Jacky Loa, Gemma A. Figtree, Jonathan Golledge, Sarah Aitken, David A. Robinson

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Subject Terms: peripheral artery disease (PAD), inflammation, therapeutics, endothelial cell dysfunction, thrombosis, angiogenesis, Diseases of the circulatory (Cardiovascular) system, RC666-701

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Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.1054576/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/835f614d8bbb416b9e36fccc5793d3dd