Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor

Authors: Ke Sun, Yong-Li Wang, Chen-Chen Hou, Da Shang, Lin-Juan Du, Lan Bai, Xing-Yu Zhang, Chuan-Ming Hao, Sheng-Zhong Duan

Source: Journal of Advanced Research, Vol 68, Iss , Pp 75-87 (2025)

Subject Terms: Hypertension, Collecting duct, NCOR1, MR, ENaC, Medicine (General), R5-920, Science (General), Q1-390

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Relation: http://www.sciencedirect.com/science/article/pii/S2090123224000535; https://doaj.org/toc/2090-1232

Access URL: https://doaj.org/article/f9e0aaa9584648d9987339eaef2ec93e

Effects of CFTR-ENaC on spinal cord edema after spinal cord injury

Authors: Shen Guowei, Zhang Yunpeng, Cheng Xinkun, Li Dongdong, Ding Zhiyong, Tian Jiwei, Chen Hui, Ding Huiming

Source: Open Medicine, Vol 19, Iss 1, Pp 387-93 (2024)

Subject Terms: lps, cftr-enac, spinal cord edema, spinal cord injury, pi3k/akt, Medicine

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Relation: https://doaj.org/toc/2391-5463

Access URL: https://doaj.org/article/48cf894b6ed948f98dd9a5006ad5440d

Evaluation of aldosterone to direct renin ratio, low renin and related Phenotypes in Afro-Colombian patients with apparent treatment resistant hypertension

Authors: C. E. Durán, M. Bustamante, M. Barbosa, E. M. Useche, J. Triviño, L. Sandoval, P. A. Moncayo, A. M. Rivas, J. S. Zapata, J. D. Hernández Quintero, S. Meza, J. S. Bolaños, J. Schweineberg, L. Mesa, J. G. Posada

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: ENaC, Afro-American, Resistant hypertension, Low renin hypertension, Amiloride, Medicine, Science

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Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/10c1cdd21fef4609b7f2f35c900d074a

Structural insights into subunit-dependent functional regulation in epithelial sodium channels

Authors: Houser, Alexandra ¹, Baconguis, Isabelle ^{2, 3, ∗}

Source: In Structure 6 February 2025 33(2):349-362

Diarylamidine activation of a brachiopod DEG/ENaC/ASIC channel

Authors: Martí-Solans, Josep ¹, Børve, Aina ², Hejnol, Andreas ², Lynagh, Timothy ^{1, ∗}

Source: In Journal of Biological Chemistry January 2025 301(1)

The co-expression of the depolarizing and hyperpolarizing mechanosensitive ion channels in mammalian retinal neurons

Authors: Vivian Y. Pang, Zhuo Yang, Samuel M. Wu, Ji-Jie Pang

Source: Frontiers in Medicine, Vol 11 (2024)

Subject Terms: TRAAK, BK, TRPV2, TRPV4, ENaC, immunocytochemistry, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1463898/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/304875d44709417396006f965506be2e

TGR5 attenuates DOCA-salt hypertension through regulating histone H3K4 methylation of ENaC in the kidney

Authors: Xu, Long ^{a, b, 1}, Wu, Xinyan ^{a, c, 1}, Long, Luosha ^{a, b}, Li, Suchun ^{d, e}, Huang, Meiying ^{a, c}, Li, Meng ^{a, b}, Feng, Pinning ^f, Levi, Moshe ^g, Chen, Wei ^{d, e}, Wang, Lei ^{h, ⁎}, Li, Chunling ^{a, b, ⁎⁎}, Wang, Weidong ^{a, c, ⁎⁎⁎}

Source: In Metabolism April 2025 165

Anticoagulation with Nafamostat Mesilate During Impella Support: A Case Report

Authors: Makiko Nakamura, Teruhiko Imamura, Yuki Hida, Toshihide Izumida, Masaki Nakagaito, Saori Nagura, Toshio Doi, Koichiro Kinugawa

Source: Medicina, Vol 61, Iss 2, p 309 (2025)

Subject Terms: thrombocytopenia, ECMO, ENaC, hyponatremia, case report, Medicine (General), R5-920

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Relation: https://www.mdpi.com/1648-9144/61/2/309; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144

Access URL: https://doaj.org/article/0c61fec629334e68b457294398d52aea

Mice lacking ASIC2 and βENaC are protected from high-fat-diet-induced metabolic syndrome

Authors: Madison Hamby, David E. Stec, Emily Hildebrandt, Donald F. Stec, Heather A. Drummond

Source: Frontiers in Endocrinology, Vol 15 (2024)

Subject Terms: degenerin, ENaC, ASIC, obesity, high fat diet, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

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Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1449344/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/3c7e9cc65eb34f8783f044e04d5924a0

A novel in-house built printed circuit board-ceria based electrochemical device for rapid detection of Epithelial Sodium Channel (ENaC), a hypertension biomarker

Authors: Riyanto Setiyono, Muhammad Ihda H.L. Zein, Pamungkas Daud, Anni Anggraeni, Yeni Wahyuni Hartati, Husein Hernandi Bahti

Source: Sensors and Actuators Reports, Vol 7, Iss , Pp 100200- (2024)

Subject Terms: Hypertension, ENaC, PCB-SPCE, Cerium, Immunosensor, UnpadStat, Instruments and machines, QA71-90

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266605392400016X; https://doaj.org/toc/2666-0539

Access URL: https://doaj.org/article/39f540f39550456f9529a2f545672cfa

Light-Controlled Modulation and Analysis of Neuronal Functions

Contributors: Bregestovski, Piotr, Matera, Carlo

Subject Terms: parietal association cortex, fear memory, c-fos, calcium activity, transgenic mice, two-photon imaging, neuromuscular junction, neurotransmitter release, acetylcholine, nicotinic receptor, calcium channel, calcium transient, Parkinson′s disease, α-synuclein, neurogenesis, neural stem cell, neural progenitor cell, astrocyte, optogenetics, astrocytes, hippocampal neurons, patch-clamp, channelrhodopsin-2, opto-α1-adrenoreceptor, photopharmacology, photoswitchable ligands, ion channels, voltage-gated ion channels, ligand-gated ion channels, homology modeling, molecular docking, molecular dynamics, enhanced sampling, genetically encoded biosensors, optopharmacology, intracellular pH, intracellular chloride, brain slices, pH and Cl− transporters, Ca2+ indicators, calcium in vivo imaging, place cells, place fields, cognitive maps, ENaC, phosphoinositides, PIP2, optogenetic, CRY2, sodium channel, CoroNa Green, azobenzene, behavior, brainwave, dopamine, GPCR, in vivo electrophysiology, photochromism, photoswitch, zebrafish, neural plasticity, tropomyosin kinase receptor B, parvalbumin-positive interneurons, calcium/calmodulin positive pyramidal neurons, V1/visual cortex, multiple regression with interaction and simple slopes analysis, Research and information: general, Biology, life sciences

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Access URL: https://directory.doabooks.org/handle/20.500.12854/96737
https://mdpi.com/books/pdfview/book/6683

Discovery and development of BI 1265162, an ENaC inhibitor for the treatment of cystic fibrosis

Authors: Betzemeier, Bodo ^a, Braun, Clemens ^b, Sieger, Peter ^b, Heckel, Armin ^c, Linz, Günter ^a, Linehan, Brian ^d, Veser, Thomas ^c, Wiedenmayer, Dieter ^c, Kley, Jörg T. ^{c, ∗}

Source: In European Journal of Medicinal Chemistry 5 February 2024 265

Extracellular vesicles from BALF of pediatric cystic fibrosis and asthma patients increase epithelial sodium channel activity in small airway epithelial cells

Authors: Al-Humiari, Mohammed A. ^a, Yu, Ling ^b, Liu, Lauren P. ^b, Nouri, Mohammad-Zaman ^c, Tuna, Kubra M. ^d, Denslow, Nancy D. ^c, Alli, Abdel A. ^{a, b, e, ⁎}

Source: In BBA - Biomembranes January 2024 1866(1)

30-Min Exposure to Tobacco Smoke Influences Airway Ion Transport—An In Vitro Study

Authors: Katarzyna Henke, Irena Balcerzak, Ewa Czepil, Alicja Bem, Elżbieta Piskorska, Dorota Olszewska-Słonina, Alina Woźniak, Karolina Szewczyk-Golec, Iga Hołyńska-Iwan

Source: Current Oncology, Vol 30, Iss 7, Pp 7007-7018 (2023)

Subject Terms: airways, CFTR, chloride, ENaC, ion transport, smoking, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://www.mdpi.com/1718-7729/30/7/508; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/895134f6275e433280acdea2d5ad0e7b

Activation of renal epithelial Na+ channels (ENaC) in infants with congenital heart disease

Authors: Laura A. Ortmann, Shyam Nandi, Yu-long Li, Hong Zheng, Kaushik P. Patel

Source: Frontiers in Pediatrics, Vol 12 (2024)

Subject Terms: ENaC, sodium retention, proteases, congenital heart disease, pediatric, Pediatrics, RJ1-570

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Relation: https://www.frontiersin.org/articles/10.3389/fped.2024.1338672/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/d804d65175ac4f48b938313818a2ba7e

The epithelial sodium channel in inflammation and blood pressure modulation

Authors: Taseer Ahmad, Lale A. Ertuglu, Sepiso K. Masenga, Thomas R. Kleyman, Annet Kirabo

Source: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

Subject Terms: epithelial sodium channel (ENaC), δ-ENaC, antigen presenting cells, inflammation, endothelium dysfunction, blood pressure, Diseases of the circulatory (Cardiovascular) system, RC666-701

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Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1130148/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/67a864c59c304fd79f51acbfc452eeb8

Sodium Intake and Related Diseases

Contributors: Strazzullo, Pasquale, Santini, Antonello, Lucarini, Massimo, Durazzo, Alessandra, Lombardi-Boccia, Ginevra, Sette, Stefania

Subject Terms: tight junction, Na+ cotransport, leaky epithelia, blood pressure, inflammation, mineralocorticoid receptor, Rac1, renal injury, salt-sensitive hypertension, salt intake, sodium, hypertension, cardiovascular risk, mortality, prognosis, salt, heart failure, ambulatory heart failure, epidemiological studies, MST3, STK24, high potassium, ENaC, NKCC2, SPAK, OSR1, WNK4, Research and information: general, Biology, life sciences, Cultural studies: food and society

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Access URL: https://directory.doabooks.org/handle/20.500.12854/81224
https://mdpi.com/books/pdfview/book/5256

Direct endothelial ENaC activation mitigates vasculopathy induced by SARS-CoV2 spike protein

Authors: Maritza J. Romero, Qian Yue, Bhupesh Singla, Jürg Hamacher, Supriya Sridhar, Auriel S. Moseley, Chang Song, Mobarak A. Mraheil, Bernhard Fischer, Markus Zeitlinger, Trinad Chakraborty, David Fulton, Lin Gan, Brian H. Annex, Gabor Csanyi, Douglas C. Eaton, Rudolf Lucas

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: Epithelial sodium channel (ENaC), SARS-CoV2 spike protein, receptor binding domain (RBD), human ACE-2, endothelial dysfunction, NADPH oxidase 2 (NOX2), Immunologic diseases. Allergy, RC581-607

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Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1241448/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/601f9caadea24ac78d5e6a33f31a23e1

Molecular Basis for Mambalgin-2 Interaction with Heterotrimeric α-ENaC/ASIC1a/γ-ENaC Channels in Cancer Cells

Authors: Ekaterina N. Lyukmanova, Maxim M. Zaigraev, Dmitrii S. Kulbatskii, Aizek B. Isaev, Ilya D. Kukushkin, Maxim L. Bychkov, Mikhail A. Shulepko, Anton O. Chugunov, Mikhail P. Kirpichnikov

Source: Toxins, Vol 15, Iss 10, p 612 (2023)

Subject Terms: three-finger toxins, acid-sensing ion channels, cancer, DEG/ENaC, ASIC1a, α-ENaC, Medicine

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Relation: https://www.mdpi.com/2072-6651/15/10/612; https://doaj.org/toc/2072-6651

Access URL: https://doaj.org/article/dfc5d92e10344ed5904eaa6a5cb5eb24

Nephrotic Syndrome: From Pathophysiology to Novel Therapeutic Approaches

Authors: Valentina-Georgiana Frățilă, Gabriela Lupușoru, Bogdan Marian Sorohan, Bogdan Obrișcă, Valentin Mocanu, Mircea Lupușoru, Gener Ismail

Source: Biomedicines, Vol 12, Iss 3, p 569 (2024)

Subject Terms: nephrotic syndrome, underfill and overfill hypothesis, serin protease, diuretic resistance, ENaC-blockers, Biology (General), QH301-705.5

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Relation: https://www.mdpi.com/2227-9059/12/3/569; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/02df6d0399844340911af95ef493b563