ImmRegInformer: an interpretable Transformer-based method for prioritizing immune-regulatory cancer drivers

Authors: Xu, Liwen, Ji, Boya, Peng, Yijun, Pi, Wending, Zeng, Xiangxiang, Zhao, Peng, Peng, Shaoliang

Source: 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2023 IEEE International Conference on. :712-717 Dec, 2023

Relation: 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

Driver mutation detected in cerebrospinal fluid despite negative liquid biopsy results

Authors: Kei Kunimasa, Daisuke Aohara, Kazumi Nishino

Source: Discover Oncology, Vol 16, Iss 1, Pp 1-5 (2025)

Subject Terms: Liquid biopsy, Cerebrospinal fluid, Cell free DNA, Gene panel, Driver mutation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2730-6011

Access URL: https://doaj.org/article/e463f876622f4b7798f28713a69addf3

An ensemble machine learning-based performance evaluation identifies top In-Silico pathogenicity prediction methods that best classify driver mutations in cancer

Authors: Subrata Das, Vatsal Patel, Shouvik Chakravarty, Arnab Ghosh, Anirban Mukhopadhyay, Nidhan K. Biswas

Source: BioData Mining, Vol 18, Iss 1, Pp 1-25 (2025)

Subject Terms: Driver mutation, Machine learning, Pathogenecity prediction algorithm, Computer applications to medicine. Medical informatics, R858-859.7, Analysis, QA299.6-433

File Description: electronic resource

Relation: https://doaj.org/toc/1756-0381

Access URL: https://doaj.org/article/593c024a4a3c471ba043c61e4b1bbdaf

An observational study on the efficacy of targeted therapy for pulmonary sarcomatoid carcinoma

Authors: Takeshi Tsuda, Tomomi Ichikawa, Masahiro Matsumoto, Isami Mizusihima, Kenji Azechi, Naoki Takata, Nozomu Murayama, Kana Hayashi, Takahiro Hirai, Zenta Seto, Kotaro Tokui, Yasuaki Masaki, Chihiro Taka, Seisuke Okazawa, Kenta Kambara, Shingo Imanishi, Hirokazu Taniguchi, Toshiro Miwa, Ryuji Hayashi, Shoko Matsui, Minehiko Inomata

Source: Discover Oncology, Vol 15, Iss 1, Pp 1-9 (2024)

Subject Terms: Driver mutation, Pleomorphic carcinoma, Survival, Treatment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2730-6011

Access URL: https://doaj.org/article/0daef32daf774bb8b141fae7e8643c1d

Efficacy of chemotherapy plus immune checkpoint inhibitors in patients with non-small cell lung cancer who have rare oncogenic driver mutations: a retrospective analysis

Authors: Teppei Yamaguchi, Junichi Shimizu, Reiko Matsuzawa, Naohiro Watanabe, Yoshitsugu Horio, Yutaka Fujiwara

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)

Subject Terms: Non-small cell lung cancer, Immune checkpoint inhibitors, Immunotherapy, Driver mutation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/1c2193dbf8174ff9817695be22a0730a

Targeted and cytotoxic inhibitors used in the treatment of lung cancers

Authors: Robert Roskoski Jr.

Source: Pharmacological Research, Vol 209, Iss , Pp 107465- (2024)

Subject Terms: Driver mutation, Immune checkpoint inhibitor, Non-small cell lung cancer, Protein kinase inhibitor, Radiation therapy, Tumor node metastasis staging, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661824004109; https://doaj.org/toc/1096-1186

Access URL: https://doaj.org/article/1098f4c94b314deb9702a8bdf2335bd8

Temporal Effect on PD‐L1 Detection and Novel Insights Into Its Clinical Implications in Non–Small Cell Lung Cancer

Authors: Gopal P. Pathak, Rashmi Shah, Mathieu Castonguay, Angela Cheng, John Fris, Rowan Murphy, Gail Darling, Alexander Ednie, Daniel French, Harry Henteleff, Aneil Mujoomdar, Madelaine Plourde, Alison Wallace, Zhaolin Xu

Source: Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)

Subject Terms: checkpoint inhibitor, driver mutation, immunotherapy, NSCLC, PD‐L1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/ff5a5695ce2448108b9d6431f5d82b1b

A New Maximum Weight Submatrix Solver Tool for Identifying Mutated Driver Pathways in Cancer using Python

Authors: Kharroubi, Fouad, El Kati, Yassine, Wang, Shu-Lin, El Jourmi, Mohammed, Ouahmane, Hassan

Source: 2020 10th Annual Computing and Communication Workshop and Conference (CCWC) Computing and Communication Workshop and Conference (CCWC), 2020 10th Annual. :0895-0900 Jan, 2020

Relation: 2020 10th Annual Computing and Communication Workshop and Conference (CCWC)

Spatial whole exome sequencing reveals the genetic features of highly-aggressive components in lung adenocarcinoma

Authors: Jianfu Li, Shan Xiong, Ping He, Peng Liang, Caichen Li, Ran Zhong, Xiuyu Cai, Zhanhong Xie, Jun Liu, Bo Cheng, Zhuxing Chen, Hengrui Liang, Shen Lao, Zisheng Chen, Jiang Shi, Feng Li, Yi Feng, Zhenyu Huo, Hongsheng Deng, Ziwen Yu, Haixuan Wang, Shuting Zhan, Yang Xiang, Huiting Wang, Yongmin Zheng, Xiaodong Lin, Jianxing He, Wenhua Liang

Source: Neoplasia: An International Journal for Oncology Research, Vol 54, Iss , Pp 101013- (2024)

Subject Terms: Invasive lung adenocarcinoma, Histological grades, Histological subtypes, Driver mutation, TTN mutation, Laser-capture microdissection, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558624000551; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/a7f9d5aab6224b4eb212dc3fc8b06c4f

Rare subclonal sequencing of breast cancers indicates putative metastatic driver mutations are predominately acquired after dissemination

Authors: Matthew R. Lawrence-Paul, Tien-chi Pan, Dhruv K. Pant, Natalie N. C. Shih, Yan Chen, George K. Belka, Michael Feldman, Angela DeMichele, Lewis A. Chodosh

Source: Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)

Subject Terms: Breast cancer, Metastasis, Rare subclonal sequencing, Ultra-deep sequencing, Genomics, Metastatic driver mutation, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/e39183bc9dda4422b08a07e9f44a1073

Mathematical modeling the gene mechanism of colorectal cancer and the effect of radiation exposure

Authors: Lingling Li, Yulu Hu, Xin Li, Tianhai Tian

Source: Mathematical Biosciences and Engineering, Vol 21, Iss 1, Pp 1186-1202 (2024)

Subject Terms: mathematical modeling, colorectal cancer, incidence rate, driver mutation, radiation exposure, Biotechnology, TP248.13-248.65, Mathematics, QA1-939

File Description: electronic resource

Relation: https://doaj.org/toc/1551-0018

Access URL: https://doaj.org/article/a0786e3ec93647ab861880c7e6a921af

A Multi-Model Based Approach for Driver Missense Identification

Authors: Soliman, Ahmed, Shyu, Mei-Ling

Source: 2018 IEEE International Conference on Information Reuse and Integration (IRI) IRI Information Reuse and Integration (IRI), 2018 IEEE International Conference on. :419-425 Jul, 2018

Relation: 2018 IEEE International Conference on Information Reuse and Integration (IRI)

Genetic/Epigenetic Alteration and Tumor Immune Microenvironment in Intrahepatic Cholangiocarcinoma: Transforming the Immune Microenvironment with Molecular-Targeted Agents

Authors: Naoshi Nishida, Masatoshi Kudo

Source: Liver Cancer, Pp 1-14 (2023)

Subject Terms: cholangiocarcinoma, immune checkpoint inhibitors, tumor immune microenvironment, driver mutation, molecular-targeted agents, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://beta.karger.com/Article/FullText/534443; https://doaj.org/toc/1664-5553

Access URL: https://doaj.org/article/afca5ee737d0431ab8c8d7797f7b80dd

Network-based prediction approach for cancer-specific driver missense mutations using a graph neural network

Authors: Narumi Hatano, Mayumi Kamada, Ryosuke Kojima, Yasushi Okuno

Source: BMC Bioinformatics, Vol 24, Iss 1, Pp 1-15 (2023)

Subject Terms: Driver mutation prediction, Cancer missense mutation, Graph neural network, Molecular interaction, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/56ed2cc9a45640999bccc12a560db9ff

Assessment of targeted therapy opportunities in sinonasal cancers using patient-derived functional tumor models

Authors: Noora Lehtinen, Janne Suhonen, Kiesha Rice, Eetu Välimäki, Mervi Toriseva, Johannes Routila, Perttu Halme, Melissa Rahi, Heikki Irjala, Ilmo Leivo, Markku Kallajoki, Matthias Nees, Teijo Kuopio, Sami Ventelä, Juha K. Rantala

Source: Translational Oncology, Vol 44, Iss , Pp 101935- (2024)

Subject Terms: Sinonasal cancer, Ex vivo drug screening, Driver mutation, Targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523324000627; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/1043b19b0c8148dc8cfad7e1e4daf8d5

Secondary Publication: Role of Molecular Targeted Drugs in Oncology

Authors: Hidekazu Kuramochi

Source: Tokyo Women's Medical University Journal, Vol 7, Iss 0, Pp 14-20 (2023)

Subject Terms: biomarker, cancer gene panel, driver mutation, molecular targeted drug, Medicine

File Description: electronic resource

Relation: https://www.jstage.jst.go.jp/article/twmuj/7/0/7_2023004/_pdf/-char/en; https://doaj.org/toc/2432-6186

Access URL: https://doaj.org/article/a59cb97705784b928c7d3149a4311920

Myeloid neoplasms in inflammatory bowel disease: A case series and review of the literature

Authors: David M. Mueller, Daniel I. Nathan, Angela Liu, John Mascarenhas, Bridget K. Marcellino

Source: Leukemia Research Reports, Vol 21, Iss , Pp 100458- (2024)

Subject Terms: Inflammatory bowel disease, Myeloid neoplasm, Thiopurine, Clonal hematopoiesis, Driver Mutation, Case Series, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213048924000487; https://doaj.org/toc/2213-0489

Access URL: https://doaj.org/article/aeaaad5a52a64853acd0da183f1cd591

The Additional Exclusions of ROS1 Fusions (In Addition to EGFR Mutation and ALK Fusions) in the Cemiplimab NSCLC FDA Indication (EMPOWER-Lung 1 and -Lung 3). Catching Up with Current Scientific View of Immunotherapy in Never-Smoker Predominant Actionable Driver Mutation Positive NSCLC?

Authors: Brazel D, Ou SI

Source: Lung Cancer: Targets and Therapy, Vol Volume 14, Pp 63-69 (2023)

Subject Terms: cemiplimab, immunotherapy, actionable driver mutation, ros1 fusion, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.dovepress.com/the-additional-exclusions-of-ros1-fusions-in-addition-to-egfr-mutation-peer-reviewed-fulltext-article-LCTT; https://doaj.org/toc/1179-2728

Access URL: https://doaj.org/article/b9a9beaa77c44696b3d3f50164437b17

Genomic landscape of pancreatic cancer in the Japanese version of the Cancer Genome Atlas

Authors: Taisuke Imamura, Ryo Ashida, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Yukiyasu Okamura, Katsuhisa Ohgi, Sumiko Ohnami, Takeshi Nagashima, Ken Yamaguchi

Source: Annals of Gastroenterological Surgery, Vol 7, Iss 3, Pp 491-502 (2023)

Subject Terms: copy number variant, driver mutation, pancreatic cancer, prognosis, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/2475-0328

Access URL: https://doaj.org/article/aee6e68457b443c18d26b791aa107919

F-18 FDG PET/CT characterization and predictive efficacy for driver mutation positive and negative pulmonary adenocarcinoma in correlation with clinico-pathologic data

Authors: Ashish Acharya K, Shelley Simon, Indirani M

Source: National Board of Examinations Journal of Medical Sciences, Vol 1, Iss 4, Pp 188-197 (2023)

Subject Terms: fdg/pet ct, driver mutation, pulmonary adenocarcinoma, metabolic parameters, egfr, alk, Medicine

File Description: electronic resource

Relation: https://natboard.edu.in/ejournal/articledtl?x=Q1k4b1Vkbk03SytYT09YazBCRElQUT09; https://doaj.org/toc/2583-7524

Access URL: https://doaj.org/article/5829e9b496b749c484b7ee8bb2cf57e8