Interleukin-4 and Atopic Dermatitis: Why Does it Matter? A Narrative Review

Authors: Tiago Torres, Pedro Mendes-Bastos, Maria J. Cruz, Bruno Duarte, Paulo Filipe, Maria J. P. Lopes, Margarida Gonçalo

Source: Dermatology and Therapy, Vol 15, Iss 3, Pp 579-597 (2025)

Subject Terms: Atopic dermatitis, Interleukin-4, Targeted therapies, Atopic march, Disease modification, Pruritus, Dermatology, RL1-803

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8210; https://doaj.org/toc/2190-9172

Access URL: https://doaj.org/article/7d6120fd896543838fcd7b943ab94857

Real-World Effectiveness of Intravenous Belimumab on Clinical Outcomes in Patients With Systemic Lupus Erythematosus in Saudi Arabia: The OBSErve Observational Study

Authors: Al-Homood IA, Almaghlouth I, Asiri AM, Hamdy H, Alhammad A, Mustafa A, Othman M, Khamashta M, Elfishawy T, Teichman L, dos Santos D, Queiroz JD, Noibi S

Source: Open Access Rheumatology: Research and Reviews, Vol Volume 17, Pp 33-45 (2025)

Subject Terms: disease activity, disease modification, glucocorticoids, monoclonal antibody, systemic lupus erythematosus, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://www.dovepress.com/real-world-effectiveness-of-intravenous-belimumab-on-clinical-outcomes-peer-reviewed-fulltext-article-OARRR; https://doaj.org/toc/1179-156X

Access URL: https://doaj.org/article/845c645ec30b461f93a8dd09d8ed7633

Real-world effectiveness of intravenous belimumab in adults with systemic lupus erythematosus: results of the observational OBSErve study in the Russian Federation

Authors: Alexander Mikhailovich Lila, Elena Aleksandrovna Aseeva, Alyona Igorevna Zagrebneva, Irina Borisovna Vinogradova, Ruzana Ramilovna Samigullina, Munther Khamashta, Tamer Elfishawy, Lindsey Teichman, Debora dos Santos, Juliana Queiroz, Larisa Alexandrovna Kniazeva, Saeed Noibi

Source: BMC Rheumatology, Vol 9, Iss 1, Pp 1-10 (2025)

Subject Terms: Belimumab, Biologic drugs, Cohort study, Disease activity, Disease modification, Glucocorticoids, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/2520-1026

Access URL: https://doaj.org/article/dfbd80e4ae5d422e8a5d4bf39960608d

Disease Modification in Asthma: Are We on the Right Way? A Multidisciplinary Expert Delphi Consensus (MODIASTHMA Consensus)

Authors: Miralles-López JC, Alvarez-Gutiérrez FJ, Delgado-Romero J, Quirce S, Soto-Campos JG, Andújar-Espinosa R, Cabrejos-Perotti S, Castilla-Martínez M, Flores-Martín I, Pajarón-Fernández MJ, Valverde-Molina J

Source: Journal of Asthma and Allergy, Vol Volume 17, Pp 1163-1171 (2024)

Subject Terms: severe asthma, disease modification, delphi process, remission, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.dovepress.com/disease-modification-in-asthma-are-we-on-the-right-way-a-multidiscipli-peer-reviewed-fulltext-article-JAA; https://doaj.org/toc/1178-6965

Access URL: https://doaj.org/article/5d1501a0370a477aac7976b6b77f9b45

Roads to remission: evolving treatment concepts in type 2 inflammatory diseases

Authors: Marek Lommatzsch, Katharina Blumchen, Lisa A. Beck, Jean Bousquet, Guy G. Brusselle, Wytske J. Fokkens, Eckard Hamelmann, Susanne Lau, Hagen Ott, Oliver Pfaar, Hugh A. Sampson, Josef S. Smolen, Christian Taube, Ingo H. Tarner, Martin Wagenmann, Thomas Werfel, Margitta Worm, Harald Renz

Source: EClinicalMedicine, Vol 80, Iss , Pp 103050- (2025)

Subject Terms: Remission, Disease modification, Type 2 inflammation, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537024006291; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/28552a17fdfb4aa7bd83f134c2224b10

Epidemiologic Risk and Prevention and Interventions in Parkinson Disease: From a Nutrition-Based Perspective

Authors: Zhang, Fan ^{1, 2, †}, Liu, Yu-Xian ^{1, †}, Zhu, Yun-Yue ², Yu, Qiu-Yan ³, Msigwa, Samwel Sylvester ¹, Zeng, Zhi-Hai ², Zhang, Xiong ¹, Wu, Hong-Mei ^{2, ⁎}, Zhu, Jian-Hong ^{1, 2, ⁎⁎}

Source: In The Journal of Nutrition January 2025

Randomized controlled trial of intermittent hypoxia in Parkinson’s disease: study rationale and protocol

Authors: Jules M. Janssen Daalen, Marjan J. Meinders, Soania Mathur, Hieronymus W.H. van Hees, Philip N. Ainslie, Dick H.J. Thijssen, Bastiaan R. Bloem

Source: BMC Neurology, Vol 24, Iss 1, Pp 1-10 (2024)

Subject Terms: Parkinson's disease, Disease modification, Disease-modifying tria, Hypoxia, hypoxic conditioning, Mitochondrial dysfunction, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/cada589cfb2e4325bb0fca7a3a9b7b05

Promoting Prevention and Targeting Remission of Asthma: A European Forum for Research and Education in Allergy and Airway Diseases Consensus Statement on Raising the Bar in Asthma Care

Authors: Jesenak, Milos ^{a, b, c}, Bobcakova, Anna ^{a, b, c}, Djukanovic, Ratko ^d, Gaga, Mina ^j, Hanania, Nicola A. ^k, Heaney, Liam G. ^h, Pavord, Ian ^e, Quirce, Santiago ^l, Ryan, Dermot ⁱ, Fokkens, Wytske ⁿ, Conti, Diego ^{m, p}, Hellings, Peter W. ^{q, r, t}, Scadding, Glenis ^{f, g}, Van Staeyen, Elizabeth ^p, Bjermer, Leif H. ^u, Diamant, Zuzana ^{o, s, v, ∗}

Source: In Chest

Disease-modifying effects of a glial-targeted inducible nitric oxide synthase inhibitor (1400W) in mixed-sex cohorts of a rat soman (GD) model of epilepsy

Authors: Suraj S. Vasanthi, Nikhil S. Rao, Manikandan Samidurai, Nyzil Massey, Christina Meyer, Meghan Gage, Mihir Kharate, Aida Almanza, Logan Wachter, Candide Mafuta, Lily Trevino, Adriana M. Carlo, Elijah Bryant, Brooke E. Corson, Morgan Wohlgemuth, Morgan Ostrander, Lucas Showman, Chong Wang, Thimmasettappa Thippeswamy

Source: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-25 (2023)

Subject Terms: Nerve agents, Status epilepticus, Disease-modification, Telemetry, Behavioral dysfunction, Spontaneous seizures, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/27b5448e94704f1a86180ed9deaf58b0

Atopic dermatitis: a need to define the disease activity

Authors: Axel De Greef, Laurence de Montjoye, Thomas Bieber, Marie Baeck

Source: Frontiers in Medicine, Vol 10 (2023)

Subject Terms: atopic dermatitis, terminology, consensus, disease activity, disease modification, disease modification treatments, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1293185/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/99efa3e04ceb4476a524a27f0635419b

Protocol for a randomized, placebo-controlled, double-blind phase IIa study of the safety, tolerability, and symptomatic efficacy of the ROCK-inhibitor Fasudil in patients with Parkinson’s disease (ROCK-PD)

Authors: Andreas W. Wolff, Helen Bidner, Yvonne Remane, Janine Zimmer, Dag Aarsland, Olivier Rascol, Richard K. Wyse, Alexander Hapfelmeier, Paul Lingor

Source: Frontiers in Aging Neuroscience, Vol 16 (2024)

Subject Terms: Parkinson’s disease, clinical trial, safety, tolerability, symptomatic efficacy, disease modification, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2024.1308577/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/a442099c606942f292441ea23995dcd7

The Importance of Early Chronic Obstructive Pulmonary Disease: A Lecture from 2022 Asian Pacific Society of Respirology

Authors: Don D. Sin

Source: Tuberculosis and Respiratory Diseases, Vol 86, Iss 2, Pp 71-81 (2023)

Subject Terms: early chronic obstructive pulmonary disease, definition, disease modification, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://e-trd.org/upload/pdf/trd-2023-0005.pdf; https://doaj.org/toc/1738-3536; https://doaj.org/toc/2005-6184

Access URL: https://doaj.org/article/14dfd33af6054f44af92d35a51b0abb4

Early intervention and disease memory in psoriasis: A literature review

Authors: Hakim Ben Abdallah, Thomas Emmanuel, Anne Bregnhøj, Claus Johansen, Lars Iversen

Source: JEADV Clinical Practice, Vol 1, Iss 4, Pp 307-316 (2022)

Subject Terms: biologics, early intervention, disease memory, disease modification, psoriasis, Dermatology, RL1-803, Diseases of the genitourinary system. Urology, RC870-923

File Description: electronic resource

Relation: https://doaj.org/toc/2768-6566

Access URL: https://doaj.org/article/5ec9ce105bc042ff8bd8c393c8f67df1

Editorial: Disease-modifying targets and strategies for Alzheimer's disease and Parkinson's disease

Authors: Xiaoya Gao

Source: Frontiers in Aging Neuroscience, Vol 15 (2023)

Subject Terms: Alzheimer's disease, Parkinson's disease, disease modification, neuroprotection, novel targets, neurodegeneration, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1247256/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/c6da3d92d4674359a86aeadd58e7a2fd

Reducing the Risk of Developing Psoriatic Arthritis in Patients with Psoriasis

Authors: Gisondi P, Bellinato F, Maurelli M, Geat D, Zabotti A, McGonagle D, Girolomoni G

Source: Psoriasis: Targets and Therapy, Vol Volume 12, Pp 213-220 (2022)

Subject Terms: psoriatic arthritis, psoriasis, therapy, prevention, early intervention, disease modification, Dermatology, RL1-803

File Description: electronic resource

Relation: https://www.dovepress.com/reducing-the-risk-of-developing-psoriatic-arthritis-in-patients-with-p-peer-reviewed-fulltext-article-PTT; https://doaj.org/toc/2230-326X

Access URL: https://doaj.org/article/238a960cfdf2458883ca481dc224ff42

Fenfluramine: a plethora of mechanisms?

Authors: Jo Sourbron, Lieven Lagae

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: fintepla, pathways, serotonin, sigma, disease modification, epilepsy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1192022/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/aff4b99698f445948668628c8d783e8c

Efficacy of Japanese cedar pollen sublingual immunotherapy tablets for Japanese cypress pollinosis

Authors: Tomoya Kurokawa, MD, PhD, Syuji Yonekura, MD, PhD, Minoru Gotoh, MD, PhD, Mitsuhiro Okano, MD, PhD, Yuriko Maekawa, BSc, Kimihiro Okubo, MD, PhD, Yoshitaka Okamoto, MD, PhD

Source: Journal of Allergy and Clinical Immunology: Global, Vol 2, Iss 2, Pp 100075- (2023)

Subject Terms: Allergy immunotherapy, sublingual immunotherapy, disease modification, sustained efficacy, Japanese cedar, Japanese cypress, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772829322000984; https://doaj.org/toc/2772-8293

Access URL: https://doaj.org/article/f8be57503f8c4b61b3602f5c6bc2d729

The effect of cardiovascular risk on disease progression in de novo Parkinson's disease patients: An observational analysis

Authors: Max J. Oosterwegel, Jesse H. Krijthe, Melina G. H. E. den Brok, Lieneke van den Heuvel, Edo Richard, Tom Heskes, Bastiaan R. Bloem, Luc J. W. Evers

Source: Frontiers in Neurology, Vol 14 (2023)

Subject Terms: Parkinson's disease, cardiovascular risk, disease modification, longitudinal modeling, BMI, hypertension, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2023.1138546/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/165cef11bcb54f09a7aba874f57068fc

Cox regression and survival analysis from the tauro-urso-deoxycholic trial in amyotrophic lateral sclerosis

Authors: Giorgio Reggiardo, Maria Lo Giudice, Stefania Lalli, Gilberto Rinaldi, Alberto Albanese

Source: Frontiers in Neurology, Vol 14 (2023)

Subject Terms: amyotrophic lateral sclerosis, tauro-urso-deoxycholic acid, bile acids, disease modification, survival, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2023.1163855/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/79e709b9ddb64182a5671278fd4e8a29

Rs205764 and rs547311 in linc00513 may influence treatment responses in multiple sclerosis patients: A pharmacogenomics Egyptian study

Authors: Nada Sherif Amin, Mostafa K. Abd El-Aziz, Mohamed Hamed, Ramez Reda Moustafa, Hend M. El Tayebi

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: pharmacogenomics, multiple sclerosis, autoimmune disease, disease-modification therapies, personalized medicine, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1087595/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/30f9350abf8f4a2a977b69f67f4dc450