Up-front blinatumomab improves MRD clearance and outcome in adult Ph– B-lineage ALL: the GIMEMA LAL2317 phase 2 study

Authors: Bassan, Renato ^{1, ∗}, Chiaretti, Sabina ², Della Starza, Irene ^{2, 3}, Santoro, Alessandra ⁴, Spinelli, Orietta ⁵, Tosi, Manuela ⁵, Elia, Loredana ², Cardinali, Deborah ², De Propris, Maria Stefania ², Piccini, Matteo ⁶, Lussana, Federico ^{5, 7}, Annunziata, Mario ⁸, Chiusolo, Patrizia ^{9, 10}, Zappasodi, Patrizia ¹¹, Borlenghi, Erika ¹², Leoncin, Matteo ¹, Califano, Catello ¹³, Bocchia, Monica ¹⁴, Di Raimondo, Francesco ¹⁵, Grimaldi, Francesco ¹⁶, Tiribelli, Mario ¹⁷, Candoni, Anna ^{17, 18}, Lico, Albana ¹⁹, Audisio, Ernesta ²⁰, Lunghi, Monia ²¹, Mianulli, Anna Maria ²², Di Trani, Mariangela ², Arena, Valentina ²³, Messina, Monica ²³, Piciocchi, Alfonso ²³, Fazi, Paola ²³, Rambaldi, Alessandro ^{5, 7}, Foà, Robin ²

Source: In Blood January 2025

Circulating cell‐free DNA for target quantification in hematologic malignancies: Validation of a protocol to overcome pre‐analytical biases

Authors: Soscia, Roberta, Della Starza, Irene, Novi, Lucia Anna, Ilari, Caterina, Ansuinelli, Michela, Cavalli, Marzia, Bellomarino, Vittorio, Cafforio, Luciana, Di Trani, Mariangela, Cazzaniga, Giovanni, Fazio, Grazia, Santoro, Alessandra, Salemi, Domenico, Spinelli, Orietta, Tosi, Manuela, Terragna, Carolina, Robustelli, Valentina, Bellissimo, Teresa, Colafigli, Gioia, Breccia, Massimo, Chiaretti, Sabina, Di Rocco, Alice, Martelli, Maurizio, Guarini, Anna, Del Giudice, Ilaria, Foà, Robin

Source: Hematological oncology. 41(1):50-60

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173068604.0x000001&indx=1&recIds=ETOCvdc_100173068604.0x000001

CD146 Molecule Expression in B Cells Acute Lymphoblastic Leukemia (B-ALLs): A Flow-Cytometric Marker for an Accurate Diagnostic Workup.

Authors: Laganà, Alessandro, Totaro, Matteo, Laura Bisegna, Maria, Elia, Loredana, Intoppa, Stefania, Beldinanzi, Marco, Matarazzo, Mabel, di Trani, Mariangela, Costa, Alessandro, Maglione, Raffaele, Mandelli, Biancamaria, Chiaretti, Sabina, Martelli, Maurizio, Stefania De Propris, Maria

Source: Mediterranean Journal of Hematology & Infectious Diseases; 2024, Vol. 16 Issue 1, p1-9, 9p

Subject Terms: PHILADELPHIA chromosome, LYMPHOBLASTIC leukemia, PROTEIN-tyrosine kinase inhibitors, ACUTE leukemia, B cells

NG2 Molecule Expression in Acute Lymphoblastic Leukemia B Cells: A Flow-Cytometric Marker for the Rapid Identification of KMT2A Gene Rearrangements.

Authors: Laura Bisegna, Maria, Peragine, Nadia, Elia, Loredana, Matarazzo, Mabel, Laura Milani, Maria, Intoppa, Stefania, Di Trani, Mariangela, Malfona, Francesco, Martelli, Maurizio, Stefania De Propris, Maria

Source: Mediterranean Journal of Hematology & Infectious Diseases; 2024, Vol. 16 Issue 1, p1-7, 7p

Subject Terms: LYMPHOBLASTIC leukemia, GENE expression, ACUTE leukemia, GENE rearrangement, CD45 antigen

Digital droplet PCR for T315I BCR::ABL1 KD mutation assessment in adult Ph-positive acute lymphoblastic leukemia with a minimal residual disease increase.

Authors: Cardinali, Deborah, Beldinanzi, Marco, Ansuinelli, Michela, Elia, Loredana, Della Starza, Irene, Bellomarino, Vittorio, Matarazzo, Mabel, Di Trani, Mariangela, Cola, Mattia, Salutari, Prassede, Cedrone, Michele, Bassan, Renato, De Gobbi, Marco, Della Porta, Matteo Giovanni, De Simone, Mariacarla, Alati, Caterina, Fracchiolla, Nicola Stefano, Lunghi, Monia, Intermesoli, Tamara, Cardinali, Valeria

Source: Leukemia & Lymphoma; Nov2023, Vol. 64 Issue 11, p1884-1887, 4p

Subject Terms: LYMPHOBLASTIC leukemia, ACUTE leukemia, PROTEIN-tyrosine kinase inhibitors, DISEASE relapse

Research Topic: Measurable Residual Disease in Hematologic Malignancies. Can digital droplet PCR improve measurable residual disease monitoring in chronic lymphoid malignancies?

Authors: Assanto, Giovanni Manfredi, Del Giudice, Ilaria, Starza, Irene Della, Soscia, Roberta, Cavalli, Marzia, Cola, Mattia, Bellomarino, Vittorio, Di Trani, Mariangela, Guarini, Anna, Foà, Robin

Source: Frontiers in Oncology; 3/14/2023, Vol. 13, p1-10, 10p

Subject Terms: HEMATOLOGIC malignancies, BLOOD diseases, NUCLEOTIDE sequencing, CHRONIC lymphocytic leukemia, CHRONIC diseases, INTRA-abdominal hypertension

Use of Ponatinib Alone or Combined with Other Therapies in Relapsed/Refractory Ph-like Acute Lymphoblastic Leukemia. a Campus ALL Real-Life Study

Authors: Lunghi, Monia, Kaiser, Francesca, Cardinali, Deborah, Basilico, Claudia, Defina, Marzia, Mastaglio, Sara, Davide, Lazzarotto, Salutari, Prassede, Piccini, Matteo, Cardinali, Valeria, Pierini, Antonio, Fracchiolla, Nicola, Di Biase, Federica, Annunziata, Mario, Di Trani, Mariangela, Ferrara, Felicetto, Pizzolo, Giovanni, Foà, Robin, Chiaretti, Sabina

Source: In Blood 28 November 2023 142 Supplement 1:1507-1507

Comparison between Dasatinib-Blinatumomab Vs Ponatinib-Blinatumomab Chemo-Free Strategy for Newly Diagnosed Ph+ Acute Lymphoblastic Leukemia Patients. Preliminary Results of the Gimema ALLL2820 Trial

Authors: Chiaretti, Sabina, Leoncin, Matteo, Elia, Loredana, Piciocchi, Alfonso, Matarazzo, Mabel, Di Trani, Mariangela, Sica, Simona, Luppi, Mario, Mancini, Valentina, Borlenghi, Erika, Imbergamo, Silvia, Selleri, Carmine, Visani, Giuseppe, Martino, Bruno, Vallisa, Daniele, Vetro, Calogero, Soddu, Stefano, Messina, Monica, Fazi, Paola, Rambaldi, Alessandro, Foà, Robin

Source: In Blood 2 November 2023 142 Supplement 1:4249-4249

Sequential Chemotherapy and Blinatumomab to Improve Minimal Residual Disease in Adult Ph- B-Lineage Acute Lymphoblastic Leukemia. Final Results of the Phase II Gimema LAL2317 Trial

Authors: Chiaretti, Sabina, Della Starza, Irene, Santoro, Alessandra, Spinelli, Orietta, Elia, Loredana, De Propris, Maria Stefania, Piccini, Matteo, Chiusolo, Patrizia, Ferrara, Felicetto, Zappasodi, Patrizia, Borlenghi, Erika, Califano, Catello, Bocchia, Monica, Mauro, Elisa, Pane, Fabrizio, Candoni, Anna, Lico, Albana, Audisio, Ernesta, Lunghi, Monia, Mianulli, Anna Maria, Di Trani, Mariangela, Arena, Valentina, Messina, Monica, Piciocchi, Alfonso, Fazi, Paola, Rambaldi, Alessandro, Foà, Robin, Bassan, Renato

Source: In Blood 2 November 2023 142 Supplement 1:826-826

Digital Droplet PCR for Minimal Residual Disease Assessment in Philadelphia-Positive Acute Lymphoblastic Leukemia Using IG/TR Genes and BCR/ABL1 as Markers. Preliminary Results of a Comparative Analysis

Authors: Beldinanzi, Marco ^*, Della Starza, Irene ^*, Cardinali, Deborah ^*, Bellomarino, Vittorio ^*, Elia, Loredana ^*, Matarazzo, Mabel ^*, Di Trani, Mariangela ^*, Chiaretti, Sabina, Foà, Robin ^*

Source: In Blood 15 November 2022 140 Supplement 1:11866-11867

Dissecting Ph-like ALL: The Role of Genomic Lesion and Minimal Residual Disease in Refining Outcome

Authors: Cardinali, Deborah ^*, Della Starza, Irene ^*, Bellomarino, Vittorio ^*, Beldinanzi, Marco ^*, Di Trani, Mariangela ^*, Ferrara, Felicetto ^*, Bocchia, Monica ^*, Salutari, Prassede ^*, Lunghi, Monia ^*, Borlenghi, Erika ^*, Piccini, Matteo ^*, Califano, Catello ^*, Piciocchi, Alfonso ^*, De Propris, Maria Stefania ^*, Foà, Robin ^*, Chiaretti, Sabina

Source: In Blood 15 November 2022 140 Supplement 1:6350-6351

Digital Droplet PCR for Minimal Residual Disease Assessment in Philadelphia-Positive Acute Lymphoblastic Leukemia Using IG/TR Genes and BCR/ABL1as Markers. Preliminary Results of a Comparative Analysis

Authors: Beldinanzi, Marco, Della Starza, Irene, Cardinali, Deborah, Bellomarino, Vittorio, Elia, Loredana, Matarazzo, Mabel, Di Trani, Mariangela, Chiaretti, Sabina, Foà, Robin

Source: Blood; November 2022, Vol. 140 Issue: 1, Number 1 Supplement 1 p11866-11867, 2p