Bevacizumab-IRDye800CW for tumor detection in fluorescence-guided meningioma surgery (LUMINA trial): a single-center phase I study.

Authors: Dijkstra, Bianca M., Cordia, Quirine C. F., Nonnekens, Julie, Jan Meersma, Gert, Donthu, Venkata Sasank, Nagengast, Wouter B., Kruijff, Schelto, den Dunnen, Wilfred F. A., Kruyt, Frank A. E., Groen, Rob J. M.

Source: Journal of Neurosurgery; Dec2024, Vol. 141 Issue 6, p1655-1666, 12p

The link between amyloid β and ferroptosis pathway in Alzheimer's disease progression.

Authors: Majerníková, Naďa, Marmolejo-Garza, Alejandro, Salinas, Casandra Salinas, Luu, Minh D. A., Zhang, Yuequ, Trombetta-Lima, Marina, Tomin, Tamara, Birner-Gruenberger, Ruth, Lehtonen, Šárka, Koistinaho, Jari, Wolters, Justina C., Ayton, Scott, den Dunnen, Wilfred F. A., Dolga, Amalia M.

Source: Cell Death & Disease; Oct2024, Vol. 15 Issue 10, p1-15, 15p

Primary Cauda Equina T-Cell Lymphoblastic Lymphoma

Authors: De Vries, Jorrit, Oterdoom, Marinus D., Den Dunnen, Wilfred F., Enting, Roelien H., Kloet, Reina W., Roeloffzen, Wilfried W., Jeltema, Hanne-Rinck R.

Source: World neurosurgery. 142:227-232

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120023930.0x000001&indx=1&recIds=ETOCvdc_100120023930.0x000001

Viral presence and immunopathology in a kidney transplant recipient with fatal COVID-19: a clinical autopsy report.

Authors: van Eijk, Larissa E, Bourgonje, Arno R, Mastik, Mirjam F, Snippe, Dirk, Bulthuis, Marian L C, Vos, Wim, Bugiani, Marianna, Smit, Jolanda M, Berger, Stefan P, van der Voort, Peter H J, van Goor, Harry, den Dunnen, Wilfred F A, Hillebrands, Jan-Luuk

Source: Journal of Leukocyte Biology; Apr2024, Vol. 115 Issue 4, p780-789, 10p

Subject Terms: KIDNEY transplantation, REVERSE transcriptase polymerase chain reaction, BK virus, COVID-19, IMMUNOPATHOLOGY, AUTOPSY

Serial FLT PET imaging to discriminate between true progression and pseudoprogression in patients with newly diagnosed glioblastoma: a long-term follow-up study

Authors: Brahm, Cyrillo G., den Hollander, Martha W., Enting, Roelien H., de Groot, Jan Cees, Solouki, A. Millad, den Dunnen, Wilfred F. A., Heesters, Mart A. A. M., Wagemakers, Michiel, Verheul, Henk M. W., de Vries, Elisabeth G. E., Pruim, Jan, Walenkamp, Annemiek M. E.

Source: European journal of nuclear medicine and molecular imaging. 45(13):2404-2412

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125532031.0x000001&indx=1&recIds=ETOCvdc_100125532031.0x000001

Glioblastoma and its treatment are associated with extensive accelerated brain aging.

Authors: Ainslie, Anna P., Klaver, Myrthe, Voshart, Daniëlle C., Gerrits, Emma, den Dunnen, Wilfred F. A., Eggen, Bart J. L., Bergink, Steven, Barazzuol, Lara

Source: Aging Cell; Mar2024, Vol. 23 Issue 3, p1-14, 14p

Subject Terms: METHYLGUANINE, DNA damage, GLIOBLASTOMA multiforme, AGING, BRAIN tumors, ALZHEIMER'S disease, TAU proteins

Cell Junction Pathology of Neural Stem Cells Is Associated With Ventricular Zone Disruption, Hydrocephalus, and Abnormal Neurogenesis

Authors: Guerra, María Montserrat, Henzi, Roberto, Ortloff, Alexander, Lichtin, Nicole, Vío, Karin, Jiménez, Antonio J., Dominguez-Pinos, María Dolores, González, César, Jara, Maria Clara, Hinostroza, Fernando, Rodríguez, Sara, Jara, Maryoris, Ortega, Eduardo, Guerra, Francisco, Sival, Deborah A., den Dunnen, Wilfred F. A., Pérez-Fígares, José M., McAllister, James P., Johanson, Conrad E., Rodríguez, Esteban M.

Source: Journal of neuropathology and experimental neurology. 74(7):653-671

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100034360143.0x000001&indx=1&recIds=ETOCvdc_100034360143.0x000001

The Correlation of In Vivo MR Spectroscopy and Ex Vivo 2-Hydroxyglutarate Concentration for the Prediction of Isocitrate Dehydrogenase Mutation Status in Diffuse Glioma.

Authors: van Dijken, Bart R. J., Jeltema, Hanne-Rinck, Kłos, Justyna, van Laar, Peter Jan, Enting, Roelien H., Maatman, Ronald G. H. J., Bijsterveld, Klaas, Den Dunnen, Wilfred F. A., Dierckx, Rudi A., Sijens, Paul E., van der Hoorn, Anouk

Source: Diagnostics (2075-4418); Sep2023, Vol. 13 Issue 17, p2791, 9p

Subject Terms: ISOCITRATE dehydrogenase, GLIOMAS, GAS chromatography/Mass spectrometry (GC-MS), SPECTROMETRY, PEARSON correlation (Statistics)

Feasibility of bevacizumab-IRDye800CW as a tracer for fluorescence-guided meningioma surgery.

Authors: Dijkstra, Bianca M., Nonnekens, Julie, Nagengast, Wouter, Kruijff, Schelto, Meersma, Gert Jan, den Dunnen, Wilfred F. A., Kruyt, Frank A. E., Groen, Rob J. M.

Source: Journal of Neurosurgery; May2023, Vol. 138 Issue 5, p1263-1272, 10p

Possible Obesogenic Effects of Bisphenols Accumulation in the Human Brain

Authors: Charisiadis, Pantelis, Andrianou, Xanthi D., van der Meer, Thomas P., den Dunnen, Wilfred F. A., Swaab, Dick F., Wolffenbuttel, Bruce H. R., Makris, Konstantinos C., van Vliet-Ostaptchouk, Jana V.

Source: Scientific reports. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131277020.0x000001&indx=1&recIds=ETOCvdc_100131277020.0x000001

Distinct DNA Methylation Patterns of Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex.

Authors: Bongaarts, Anika, Mijnsbergen, Caroline, Anink, Jasper J., Jansen, Floor E., Spliet, Wim G. M., den Dunnen, Wilfred F. A., Coras, Roland, Blümcke, Ingmar, Paulus, Werner, Gruber, Victoria E., Scholl, Theresa, Hainfellner, Johannes A., Feucht, Martha, Kotulska, Katarzyna, Jozwiak, Sergiusz, Grajkowska, Wieslawa, Buccoliero, Anna Maria, Caporalini, Chiara, Giordano, Flavio, Genitori, Lorenzo

Source: Cellular & Molecular Neurobiology; Nov2022, Vol. 42 Issue 8, p2863-2892, 30p

Subject Terms: TUBEROUS sclerosis, DNA methylation, ASTROCYTOMAS, BRAIN tumors, GENE expression

CD146 increases stemness and aggressiveness in glioblastoma and activates YAP signaling.

Authors: Liang, Yuanke, Voshart, Daniëlle, Paridaen, Judith T. M. L., Oosterhof, Nynke, Liang, Dong, Thiruvalluvan, Arun, Zuhorn, Inge S., den Dunnen, Wilfred F. A., Zhang, Guojun, Lin, Haoyu, Barazzuol, Lara, Kruyt, Frank A. E.

Source: Cellular & Molecular Life Sciences; Aug2022, Vol. 79 Issue 8, p1-39, 39p

Histological characterisation of segmental neuromuscular dysfunction in fetuses with spina bifida aperta

Authors: Sollie Krystyna M, Verbeek Renate J, Brouwer Oebele F, Sival Deborah A, den Dunnen Wilfred F

Source: Cerebrospinal Fluid Research, Vol 3, Iss Suppl 1, p S25 (2006)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1743-8454

Access URL: https://doaj.org/article/56023e3ca67e4f83a46f4abaa92e9502

Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation.

Authors: Zois, Christos E., Hendriks, Anne M., Haider, Syed, Pires, Elisabete, Bridges, Esther, Kalamida, Dimitra, Voukantsis, Dimitrios, Lagerholm, B. Christoffer, Fehrmann, Rudolf S. N., den Dunnen, Wilfred F. A., Tarasov, Andrei I., Baba, Otto, Morris, John, Buffa, Francesca M., McCullagh, James S. O., Jalving, Mathilde, Harris, Adrian L.

Source: Cell Death & Disease; Jun2022, Vol. 13 Issue 6, p1-15, 15p

The developmental stage of the medulloblastoma cell-of-origin restricts Sonic hedgehog pathway usage and drug sensitivity.

Authors: Smit, Marlinde J., Martini, Tosca E. I., Armandari, Inna, Bǒkaj, Irena, Zomerman, Walderik W., de Camargo Magalhães, Eduardo S., Siragna, Zillah, Meeuwsen, Tiny G. J., Scherpen, Frank J. G., Schoots, Mirthe H., Ritsema, Martha, den Dunnen, Wilfred F. A., Hoving, Eelco W., Paridaen, Judith T. M. L., de Haan, Gerald, Guryev, Victor, Bruggeman, Sophia W. M.

Source: Journal of Cell Science; Jun2022, Vol. 135 Issue 11, p1-14, 14p

Subject Terms: HEDGEHOG signaling proteins, MEDULLOBLASTOMA, GENE expression, TRANSCRIPTOMES, INFANTS

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The Potential of Ferroptosis-Targeting Therapies for Alzheimer's Disease: From Mechanism to Transcriptomic Analysis.

Authors: Majerníková, Nad'a, den Dunnen, Wilfred F. A., Dolga, Amalia M.

Source: Frontiers in Aging Neuroscience; 12/20/2021, Vol. 13, p1-14, 14p

Subject Terms: ALZHEIMER'S disease, APOPTOSIS, TAU proteins, TRANSCRIPTOMES, BLEPHAROPTOSIS

COVID-19: immunopathology, pathophysiological mechanisms, and treatment options.

Authors: van Eijk, Larissa E., Binkhorst, Mathijs, Bourgonje, Arno R., Offringa, Annette K., Mulder, Douwe J., Bos, Eelk M., Kolundzic, Nikola, Abdulle, Amaal E., van der Voort, Peter H. J., Olde Rikkert, Marcel G. M., van der Hoeven, Johannes G., den Dunnen, Wilfred F. A., Hillebrands, Jan-Luuk, van Goor, Harry

Source: Journal of Pathology; Jul2021, Vol. 254 Issue 4, p307-331, 25p

Subject Terms: COVID-19, COVID-19 pandemic, ADULT respiratory distress syndrome, IMMUNOPATHOLOGY, PATHOLOGICAL physiology

Growth-Factor-Driven Rescue to Receptor Tyrosine Kinase (RTK) Inhibitors through Akt and Erk Phosphorylation in Pediatric Low Grade Astrocytoma and Ependymoma.

Authors: Sie, Mariska¹, den Dunnen, Wilfred F. A.², Lourens, Harm Jan¹, Meeuwsen-de Boer, Tiny G. J.¹, Scherpen, Frank J. G.¹, Zomerman, Walderik W.¹, Kampen, Kim R.¹, Hoving, Eelco W.³, de Bont, Eveline S. J. M.¹ e.s.j.m.de.bont@umcg.nl

Source: PLoS ONE. Mar2015, Vol. 10 Issue 3, p1-16. 16p.

Subject Terms: *BRAIN tumors, *PROTEIN-tyrosine kinase inhibitors, *PHOSPHORYLATION, *PEDIATRICS, *ASTROCYTOMAS, *EPENDYMOMA, *VASCULAR endothelial growth factor receptors

Evaluation of Ac-Lys0(IRDye800CW)Tyr3-octreotate as a novel tracer for SSTR2-targeted molecular fluorescence guided surgery in meningioma.

Authors: Dijkstra, Bianca M., de Jong, Marion, Stroet, Marcus C. M., Andreae, Fritz, Dulfer, Sebastiaan E., Everts, Marieke, Kruijff, Schelto, Nonnekens, Julie, den Dunnen, Wilfred F. A., Kruyt, Frank A. E., Groen, Rob J. M.

Source: Journal of Neuro-Oncology; Jun2021, Vol. 153 Issue 2, p211-222, 12p