Efficacy of once-daily tiotropium Respimat in adults with asthma at GINA Steps 2–5

Authors: Buhl, Roland, FitzGerald, J.M., Meltzer, Eli O., de la Hoz, Alberto, Sigmund, Ralf, Kerstjens, Huib A.M., Bleecker, Eugene R.

Source: In Pulmonary Pharmacology & Therapeutics February 2020 60

Tiotropium Respimat® add-on therapy to inhaled corticosteroids in patients with symptomatic asthma improves clinical outcomes regardless of baseline characteristics

Authors: Casale, Thomas B., Aalbers, René, Bleecker, Eugene R., Meltzer, Eli O., Zaremba-Pechmann, Liliana, de la Hoz, Alberto, Kerstjens, Huib A.M.

Source: In Respiratory Medicine October-November 2019 158:97-109

Tiotropium/Olodaterol Delays Clinically Important Deterioration Compared with Tiotropium Monotherapy in Patients with Early COPD: a Post Hoc Analysis of the TONADO® Trials

Authors: Rabe, Klaus F., Chalmers, James D., Miravitlles, Marc, Kocks, Janwillem W. H., Tsiligianni, Ioanna, de la Hoz, Alberto, Xue, Wenqiong, Singh, Dave, Ferguson, Gary T., Wedzicha, Jadwiga

Source: Advances in therapy. 38(1):579-593

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194066315.0x000001&indx=1&recIds=ETOCvdc_100194066315.0x000001

Tiotropium/Olodaterol Decreases Exacerbation Rates Compared with Tiotropium in a Range of Patients with COPD: Pooled Analysis of the TONADO®/DYNAGITO® Trials

Authors: Wedzicha, Jadwiga A., Buhl, Roland, Singh, Dave, Vogelmeier, Claus F., de la Hoz, Alberto, Xue, Wenqiong, Anzueto, Antonio, Calverley, Peter M. A.

Source: Advances in therapy. 37(10):4266-4279

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176339531.0x000001&indx=1&recIds=ETOCvdc_100176339531.0x000001

Benefits of Tiotropium/Olodaterol Compared with Tiotropium in Patients with COPD Receiving only LAMA at Baseline: Pooled Analysis of the TONADO® and OTEMTO® Studies

Authors: Buhl, Roland, Singh, Dave, de la Hoz, Alberto, Xue, Wenqiong, Ferguson, Gary T.

Source: Advances in therapy. 37(8):3485-3499

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174310459.0x000001&indx=1&recIds=ETOCvdc_100174310459.0x000001

Efficacy of Tiotropium/Olodaterol Compared with Tiotropium as a First-Line Maintenance Treatment in Patients with COPD Who Are Naïve to LAMA, LABA and ICS: Pooled Analysis of Four Clinical Trials

Authors: Buhl, Roland, de la Hoz, Alberto, Xue, Wenqiong, Singh, Dave, Ferguson, Gary T.

Source: Advances in therapy. 37(10):4175-4189

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174315212.0x000001&indx=1&recIds=ETOCvdc_100174315212.0x000001

A comparison of tiotropium, long-acting β2-agonists and leukotriene receptor antagonists on lung function and exacerbations in paediatric patients with asthma

Authors: Vogelberg, Christian, Goldstein, Stanley, Graham, LeRoy, Kaplan, Alan, de la Hoz, Alberto, Hamelmann, Eckard

Source: Respiratory research. 21(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127200381.0x000001&indx=1&recIds=ETOCvdc_100127200381.0x000001

Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials

Authors: Singh, Dave, Wedzicha, Jadwiga A., Siddiqui, Salman, de la Hoz, Alberto, Xue, Wenqiong, Magnussen, Helgo, Miravitlles, Marc, Chalmers, James D., Calverley, Peter M. A.

Source: Respiratory research. 21(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171925293.0x000001&indx=1&recIds=ETOCvdc_100171925293.0x000001

EFFECTIVENESS OF COPD MAINTENANCE THERAPY WITH LAMA/LABA VS LAMA/LABA/ICS IN A UNITED STATES CLAIMS DATABASE

Authors: QUINT, JENNIFER, MONTONEN, JUKKA, HE, XINTONG, DE LA HOZ, ALBERTO, ESPOSITO, DAINA

Source: Chest. 160(S):A1863-A1864

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148275171.0x000001&indx=1&recIds=ETOCvdc_100148275171.0x000001

Factors associated with health status and exacerbations in COPD maintenance therapy with dry powder inhalers.

Authors: W. H. Kocks, Janwillem, Wouters, Hans, Bosnic-Anticevich, Sinthia, van Cooten, Joyce, Correia de Sousa, Jaime, Cvetkovski, Biljana, Dekhuijzen, Richard, Dijk, Lars, Dvortsin, Evgeni, Garcia Pardo, Marina, Gardev, Asparuh, Gawlik, Radosław, van Geer - Postmus, Iris, van der Ham, Iris, Harbers, Marten, de la Hoz, Alberto, Janse, Ymke, Kerkhof, Marjan, Lavorini, Federico, Maricoto, Tiago

Source: NPJ Primary Care Respiratory Medicine; 5/26/2022, Vol. 32 Issue 1, p1-10, 10p

A Pooled Analysis of Mortality in Patients with COPD Receiving Dual Bronchodilation with and without Additional Inhaled Corticosteroid.

Authors: Miravitlles, Marc, Verhamme, Katia, Calverley, Peter MA, Dreher, Michael, Bayer, Valentina, Gardev, Asparuh, de la Hoz, Alberto, Wedzicha, Jadwiga, Price, David

Source: International Journal of COPD; Mar2022, Vol. 17, p545-558, 14p

Impact of PIF, Inhalation Technique and Medication Adherence on Health Status and Exacerbations in COPD: Protocol of a Real-World Observational Study (PIFotal COPD Study).

Authors: Leving, Marika, Wouters, Hans, de la Hoz, Alberto, Bosnic-Anticevich, Sinthia, Dekhuijzen, Richard, Gardev, Asparuh, Lavorini, Federico, Meijer, Jiska, Price, David, Rodríguez, Miguel Román, Tsiligianni, Ioanna, Usmani, Omar, Wijnsma, Birgit, Kocks, Janwillem

Source: Pulmonary Therapy; Dec2021, Vol. 7 Issue 2, p591-606, 16p

Subject Terms: PATIENT compliance, OBSTRUCTIVE lung diseases, PRIMARY care, TREATMENT effectiveness, INSTITUTIONAL review boards

TRONARTO: A Randomized, Placebo-Controlled Study of Tiotropium/Olodaterol Delivered via Soft Mist Inhaler in COPD Patients Stratified by Peak Inspiratory Flow.

Authors: Mahler, Donald A, Ludwig-Sengpiel, Andrea, Ferguson, Gary T, de la Hoz, Alberto, Ritz, John, Shaikh, Asif, Watz, Henrik

Source: International Journal of COPD; Aug2021, Vol. 16, p2455-2465, 11p

Effectiveness and Safety of COPD Maintenance Therapy with Tiotropium/Olodaterol versus LABA/ICS in a US Claims Database.

Authors: Quint, Jennifer K., Montonen, Jukka, Esposito, Daina B., He, Xintong, Koerner, Leslie, Wallace, Laura, de la Hoz, Alberto, Miravitlles, Marc

Source: Advances in Therapy; May2021, Vol. 38 Issue 5, p2249-2270, 22p

Subject Terms: ADRENERGIC beta agonists, RESEARCH, COMBINATION drug therapy, ADRENOCORTICAL hormones, HETEROCYCLIC compounds, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, BRONCHODILATOR agents, TREATMENT effectiveness, COMPARATIVE studies, OBSTRUCTIVE lung diseases, INHALATION administration, MUSCARINIC antagonists

Effects of Tiotropium/Olodaterol on Activity-Related Breathlessness, Exercise Endurance and Physical Activity in Patients with COPD: Narrative Review with Meta-/Pooled Analyses.

Authors: Maltais, François, de la Hoz, Alberto, Casaburi, Richard, O'Donnell, Denis

Source: Advances in Therapy; Feb2021, Vol. 38 Issue 2, p835-853, 19p

Tiotropium/Olodaterol Delays Clinically Important Deterioration Compared with Tiotropium Monotherapy in Patients with Early COPD: a Post Hoc Analysis of the TONADO^® Trials.

Authors: Rabe, Klaus F., Chalmers, James D., Miravitlles, Marc, Kocks, Janwillem W. H., Tsiligianni, Ioanna, de la Hoz, Alberto, Xue, Wenqiong, Singh, Dave, Ferguson, Gary T., Wedzicha, Jadwiga

Source: Advances in Therapy; 2021, Vol. 38 Issue 1, p579-593, 15p

The effect of tiotropium/olodaterol versus fluticasone propionate/salmeterol on left ventricular filling and lung hyperinflation in patients with COPD.

Authors: Herth, Felix, Hohlfeld, Jens M., Haas, Johannes, de la Hoz, Alberto, Xidong Jin, Kreitner, Karl-Friedrich, Vogelmeier, Claus, Vogel-Claussen, Jens, Watz, Henrik

Source: BMJ Open Respiratory Research; 12/2/2020, p1-5, 5p

No Influence on Cardiac Arrhythmia or Heart Rate from Long-Term Treatment with Tiotropium/Olodaterol versus Monocomponents by Holter ECG Analysis in Patients with Moderate-to-Very-Severe COPD.

Authors: Andreas, Stefan, Bothner, Ulrich, de la Hoz, Alberto, Kloer, Isabel, Trampisch, Matthias, Alter, Peter

Source: International Journal of COPD; Aug2020, Vol. 15, p1945-1953, 9p

Absence of Adverse Effects of Tiotropium/Olodaterol Compared with the Monocomponents on Long-Term Heart Rate and Blood Pressure in Patients with Moderate-to-Very-Severe COPD.

Authors: Andreas, Stefan, McGarvey, Lorcan, Bothner, Ulrich, Trampisch, Matthias, de la Hoz, Alberto, Fležar, Matjaz, Buhl, Roland, Alter, Peter

Source: International Journal of COPD; Aug2020, Vol. 15, p1935-1944, 10p

A Post Hoc Holter ECG Analysis of Olodaterol and Formoterol in Moderate-to-Very-Severe COPD.

Authors: Andreas, Stefan, Bothner, Ulrich, de la Hoz, Alberto, Kloer, Isabel, Trampisch, Matthias, Alter, Peter

Source: International Journal of COPD; Aug2020, Vol. 15, p1955-1965, 11p