Harnessing imaging tools to guide immunotherapy trials: summary from the National Cancer Institute Cancer Imaging Steering Committee workshop

Authors: Shankar, Lalitha K, Schöder, Heiko, Sharon, Elad, Wolchok, Jedd, Knopp, Michael V, Wahl, Richard L, Ellingson, Benjamin M, Hall, Nathan C, Yaffe, Martin J, Towbin, Alexander J, Farwell, Michael D, Pryma, Daniel, Poussaint, Tina Young, Wright, Chadwick L, Schwartz, Lawrence, Harisinghani, Mukesh, Mahmood, Umar, Wu, Anna M, Leung, David, de Vries, Elisabeth G E, Tang, Ying, Beach, Gillian, Reeves, Steven A

Source: Lancet oncology. 24(3):e133-e143

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Cancer medicines on the WHO Model List of Essential Medicines: processes, challenges, and a way forward

Authors: Jenei, Kristina, Aziz, Zeba, Booth, Christopher, Cappello, Bernadette, Ceppi, Francesco, de Vries, Elisabeth G E, Fojo, Antonio, Gyawali, Bishal, Ilbawi, Andre, Lombe, Dorothy, Sengar, Manju, Sullivan, Richard, Trapani, Dario, Huttner, Benedikt D, Moja, Lorenzo ^*

Source: In The Lancet Global Health December 2022 10(12):e1860-e1866

Dose optimisation to improve access to effective cancer medicines.

Authors: Tannock, Ian F¹ (AUTHOR), de Vries, Elisabeth G E² (AUTHOR), Fojo, Antonio³ (AUTHOR), Buyse, Marc⁴ (AUTHOR), Moja, Lorenzo^1,5 (AUTHOR) mojal@who.int

Source: Lancet Oncology. Mar2025, Vol. 26 Issue 3, pe171-e180. 10p.

Subject Terms: *IMMUNE checkpoint inhibitors, *LOW-income countries, *TREATMENT effectiveness, *STATISTICAL significance, *MIDDLE-income countries

mRNA-1273 COVID-19 vaccination in patients receiving chemotherapy, immunotherapy, or chemoimmunotherapy for solid tumours: a prospective, multicentre, non-inferiority trial

Authors: Oosting, Sjoukje F ^*, van der Veldt, Astrid A M ^{*, *}, GeurtsvanKessel, Corine H, Fehrmann, Rudolf S N, van Binnendijk, Rob S, Dingemans, Anne-Marie C, Smit, Egbert F, Hiltermann, T Jeroen N, den Hartog, Gerco, Jalving, Mathilda, Westphal, Tatjana T, Bhattacharya, Arkajyoti, van der Heiden, Marieke, Rimmelzwaan, Guus F, Kvistborg, Pia, Blank, Christian U, Koopmans, Marion P G, Huckriede, Anke L W, van Els, Cecile A C M, Rots, Nynke Y, van Baarle, Debbie, Haanen, John B A G, de Vries, Elisabeth G E

Source: In The Lancet Oncology December 2021 22(12):1681-1691

Access to cancer medicines deemed essential by oncologists in 82 countries: an international, cross-sectional survey

Authors: Fundytus, Adam, Sengar, Manju, Lombe, Dorothy, Hopman, Wilma, Jalink, Matthew, Gyawali, Bishal, Trapani, Dario, Roitberg, Felipe, De Vries, Elisabeth G E, Moja, Lorenzo, Ilbawi, André, Sullivan, Richard, Booth, Christopher M ^*

Source: In The Lancet Oncology October 2021 22(10):1367-1377

Mesothelin/CD3 Half-Life—Extended Bispecific T-Cell Engager Molecule Shows Specific Tumor Uptake and Distributes to Mesothelin and CD3-Expressing Tissues

Authors: Suurs, Frans V., Lorenczewski, Grit, Bailis, Julie M., Stienen, Sabine, Friedrich, Matthias, Lee, Fei, van der Vegt, Bert, de Vries, Elisabeth G. E., de Groot, Derk Jan A., Hooge, Marjolijn N. Lub-de

Source: Journal of nuclear medicine. 62(12):1797-1804

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Molecular imaging in lymphoma beyond 18F-FDG-PET: understanding the biology and its implications for diagnostics and therapy

Authors: Kahle, Xaver U, Montes de Jesus, Filipe M, Glaudemans, Andor W J M, Lub-de Hooge, Marjolijn N, Jorritsma-Smit, Annelies, Plattel, Wouter J, van Meerten, Tom, Diepstra, Arjan, van den Berg, Anke, Kwee, Thomas C, Noordzij, Walter, de Vries, Elisabeth G E, Nijland, Marcel ^*

Source: In The Lancet Haematology June 2020 7(6):e479-e489

Immunogenicity after second and third mRNA-1273 vaccination doses in patients receiving chemotherapy, immunotherapy, or both for solid tumours

Authors: Oosting, Sjoukje F, van der Veldt, Astrid A M, Fehrmann, Rudolf S N, GeurtsvanKessel, Corine H, van Binnendijk, Rob S, Dingemans, Anne-Marie C, Smit, Egbert F, Hiltermann, T Jeroen N, den Hartog, Gerco, Jalving, Mathilda, Westphal, Tatjana T, Bhattacharya, Arkajyoti, de Wilt, Faye, Boerma, Annemarie, van Zijl, Lisanne, Rimmelzwaan, Guus F, Kvistborg, Pia, van Els, Cecile A C M, Rots, Nynke Y, van Baarle, Debbie, Haanen, John B A G, de Vries, Elisabeth G E

Source: Lancet oncology. 23(7):833-835

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Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study

Authors: Banerji, Udai, van Herpen, Carla M L, Saura, Cristina, Thistlethwaite, Fiona, Lord, Simon, Moreno, Victor, Macpherson, Iain R, Boni, Valentina, Rolfo, Christian, de Vries, Elisabeth G E, Rottey, Sylvie, Geenen, Jill, Eskens, Ferry, Gil-Martin, Marta, Mommers, Ellen C, Koper, Norbert P, Aftimos, Philippe

Source: In The Lancet Oncology August 2019 20(8):1124-1135

Molecular Imaging of PD-L1 Expression and Dynamics with the Adnectin-Based PET Tracer ^1^8F-BMS-986192

Authors: Stutvoet, Thijs S., van der Veen, Elly L., Kol, Arjan, Antunes, Inês F., de Vries, Erik F. J., Hospers, Geke A. P., de Vries, Elisabeth G. E., de Jong, Steven, Hooge, Marjolijn N. Lub-de

Source: Journal of nuclear medicine. 61(12):1839-1844

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The Biodistribution of a CD3 and EpCAM Bispecific T-Cell Engager Is Driven by the CD3 Arm

Authors: Suurs, Frans V., Lorenczewski, Grit, Stienen, Sabine, Friedrich, Matthias, de Vries, Elisabeth G. E., de Groot, Derk Jan A., Hooge, Marjolijn N. Lub-de

Source: Journal of nuclear medicine. 61(11):1594-1601

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Development and Evaluation of Interleukin-2—Derived Radiotracers for PET Imaging of T Cells in Mice

Authors: van der Veen, Elly L., Suurs, Frans V., Cleeren, Frederik, Bormans, Guy, Elsinga, Philip H., Hospers, Geke A. P., Hooge, Marjolijn N. Lub-de, de Vries, Elisabeth G. E., de Vries, Erik F. J., Antunes, Inês F.

Source: Journal of nuclear medicine. 61(9):1355-1360

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Use of selective serotonin reuptake inhibitors is associated with very low plasma-free serotonin concentrations in humans

Authors: Peters, Marloes A. M., van Faassen, Martijn, de Jong, Wilhelmina H. A., Bouma, Grietje, Meijer, Coby, Walenkamp, Annemiek M. E., de Vries, Elisabeth G. E., Oosting, Sjoukje F., Ruhé, Henricus G., Kema, Ido P.

Source: Annals of clinical biochemistry. 57(1):59-63

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622648050&indx=1&recIds=ETOCRN622648050

Microparticles from tumors exposed to radiation promote immune evasion in part by PD-L1

Authors: Timaner, Michael, Kotsofruk, Ruslana, Raviv, Ziv, Magidey, Ksenia, Shechter, Dvir, Kan, Tal, Nevelsky, Alexander, Daniel, Shahar, de Vries, Elisabeth G. E., Zhang, Tongwu, Kaidar-Person, Orit, Kerbel, Robert S., Shaked, Yuval

Source: Oncogene. 39(1):187-203

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193644869.0x000001&indx=1&recIds=ETOCvdc_100193644869.0x000001

Neuroendocrine tumours and their microenvironment

Authors: de Hosson, Lotte D., Takkenkamp, Tim J., Kats-Ugurlu, Gursah, Bouma, Grietje, Bulthuis, Marian, de Vries, Elisabeth G. E., van Faassen, Martijn, Kema, Ido P., Walenkamp, Annemiek M. E.

Source: Cancer immunology, immunotherapy. 69(8):1449-1459

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mRNA-1273 vaccination induces polyfunctional memory CD4 and CD8 T cell responses in patients with solid cancers undergoing immunotherapy or/and chemotherapy.

Authors: Gangaev, Anastasia, van Sleen, Yannick, Brandhorst, Nicole, Hoefakker, Kelly, Prajapati, Bimal, Singh, Amrita, Boerma, Annemarie, van der Heiden, Marieke, Oosting, Sjoukje F., van der Veldt, Astrid A. M., Hiltermann, T. Jeroen N., GeurtsvanKessel, Corine H., Dingemans, Anne-Marie C., Smit, Egbert F., de Vries, Elisabeth G. E., Haanen, John B. A. G., Kvistborg, Pia, van Baarle, Debbie

Source: Frontiers in Immunology; 2024, p1-13, 13p

Subject Terms: T cells, CANCER chemotherapy, COVID-19 vaccines, CANCER cells, FLOW cytometry

Clinical trial design for systemic agents in patients with brain metastases from solid tumours: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group

Authors: Camidge, D Ross, Lee, Eudocia Q, Lin, Nancy U, Margolin, Kim, Ahluwalia, Manmeet S, Bendszus, Martin, Chang, Susan M, Dancey, Janet, de Vries, Elisabeth G E, Harris, Gordon J, Hodi, F Stephen, Lassman, Andrew B, Macdonald, David R, Peereboom, David M, Schiff, David, Soffietti, Ricardo, van den Bent, Martin J, Wefel, Jeffrey S, Wen, Patrick Y

Source: In The Lancet Oncology January 2018 19(1):e20-e32

Interlesional Heterogeneity of Metastatic Neuroendocrine Tumors Based on 18F-DOPA PET/CT

Authors: de Hosson, Lotte D., van der Loo–van der Schaaf, Aline M., Boellaard, Ronald, van Snick, Johannes H., de Vries, Elisabeth G. E., Brouwers, Adrienne H., Walenkamp, Annemiek M. E.

Source: Clinical nuclear medicine. 44(8):612-619

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Interobserver reproducibility of tumor uptake quantification with 89Zr-immuno-PET: a multicenter analysis

Authors: Jauw, Yvonne W. S., Bensch, Frederike, Brouwers, Adrienne H., Hoekstra, Otto S., Zijlstra, Josée M., Pieplenbosch, Simone, Schröder, Carolien P., Zweegman, Sonja, van Dongen, Guus A. M. S., Menke-van der Houven van Oordt, C. Willemien, de Vries, Elisabeth G. E., de Vet, Henrica C. W., Boellaard, Ronald, Huisman, Marc C.

Source: European journal of nuclear medicine and molecular imaging. 46(9):1840-1849

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Lesion detection by [89Zr]Zr-DFO-girentuximab and [18F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma

Authors: Verhoeff, Sarah R., van Es, Suzanne C., Boon, Eline, van Helden, Erik, Angus, Lindsay, Elias, Sjoerd G., Oosting, Sjoukje F., Aarntzen, Erik H., Brouwers, Adrienne H., Kwee, Thomas C., Heskamp, Sandra, Hoekstra, Otto S., Verheul, Henk, van der Veldt, Astrid A. M., de Vries, Elisabeth G. E., Boerman, Otto C., van der Graaf, Winette T. A., Oyen, Wim J. G., van Herpen, Carla M. L.

Source: European journal of nuclear medicine and molecular imaging. 46(9):1931-1939

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125526967.0x000001&indx=1&recIds=ETOCvdc_100125526967.0x000001