Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

Authors: Shafi, Ayesha A., Schiewer, Matthew J., de Leeuw, Renée, Dylgjeri, Emanuela, McCue, Peter A., Shah, Neelima, Gomella, Leonard G., Lallas, Costas D., Trabulsi, Edouard J., Centenera, Margaret M., Hickey, Theresa E., Butler, Lisa M., Raj, Ganesh V., Tilley, Wayne D., Cukierman, Edna, Knudsen, Karen E.

Source: In European Urology Oncology September 2018 1(4):325-337

Tumor cell heterogeneity and resistance; report from the 2018 Coffey‐Holden Prostate Cancer Academy Meeting

Authors: Miyahira, Andrea K., Den, Robert B., Carlo, Maria I., de Leeuw, Renée, Hope, Thomas A., Karzai, Fatima, McKay, Rana R., Salami, Simpa S., Simons, Jonathan W., Pienta, Kenneth J., Soule, Howard R.

Source: Prostate. 79(3):244-258

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083164317.0x000001&indx=1&recIds=ETOCvdc_100083164317.0x000001

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes

Authors: McCann, Jennifer J., Vasilevskaya, Irina A., McNair, Christopher, Gallagher, Peter, Neupane, Neermala Poudel, de Leeuw, Renée, Shafi, Ayesha A., Dylgjeri, Emanuela, Mandigo, Amy C., Schiewer, Matthew J., Knudsen, Karen E.

Source: Oncogene; 20240101, Issue: Preprints p1-15, 15p

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Editorial: Response and Resistance in Castration-Resistant Prostate Cancer.

Authors: de Leeuw, Renée, Cao, Qi, Lam, Hung-Ming

Source: Frontiers in Oncology; 10/23/2020, Vol. 11, pN.PAG-N.PAG, 3p

Subject Terms: CASTRATION-resistant prostate cancer, PROSTATE cancer

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SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors.

Authors: Akihiro Yoshida^1,2 jad283@case.edu, Yiwen Bu¹, Shuo Qie¹, Wrangle, John³, Camp, E. Ramsay⁴, Hazard, E. Starr⁵, Hardiman, Gary^3,5,6, de Leeuw, Renée^7,8, Knudsen, Karen E.⁷, Diehl, J. Alan¹ axy234@case.edu

Source: Science Advances. 9/1/2019, Vol. 5 Issue 9, p1-15. 15p.