Effect of E7777 Immunogenicity on Pharmacokinetics, Efficacy, and Safety in Adult Patients With Relapsed or Refractory Cutaneous T‐Cell Lymphoma.

Authors: Thway, Theingi M.¹ (AUTHOR) theingi_thway@eisai.com, Aluri, Jagadeesh¹ (AUTHOR), Lalovic, Bojan² (AUTHOR), Ooi, Chean E.³ (AUTHOR), Sauter, Nicholas³ (AUTHOR), Xing, Dongyuan³ (AUTHOR), Czuczman, Myron⁴ (AUTHOR), Yasuda, Sanae¹ (AUTHOR)

Source: CTS: Clinical & Translational Science. Mar2025, Vol. 18 Issue 3, p1-12. 12p.

Subject Terms: *PHARMACOKINETICS, *CUTANEOUS T-cell lymphoma, *IMMUNE response, *ANTI-antibodies, *SAFETY, *TREATMENT effectiveness, *CLINICAL trials, *THERAPEUTIC use of proteins

The CD39/CD73/Adenosine and NAD/CD38/CD203a/CD73 Axis in Cutaneous T-Cell Lymphomas.

Authors: Lin, Liyun¹ (AUTHOR) liyun.lin@unito.it, Roccuzzo, Gabriele² (AUTHOR) gabriele.roccuzzo@unito.it, Yakymiv, Yuliya¹ (AUTHOR) yuliya.yakymiv@unito.it, Marchisio, Sara¹ (AUTHOR) sara.marchisio@unito.it, Ortolan, Erika¹ (AUTHOR) erika.ortolan@unito.it, Funaro, Ada¹ (AUTHOR) ada.funaro@unito.it, Senetta, Rebecca³ (AUTHOR) rebecca.senetta@unito.it, Pala, Valentina² (AUTHOR) v.pala@unito.it, Bagot, Martine⁴ (AUTHOR) martine.bagot@gmail.com, de Masson, Adèle⁴ (AUTHOR) adele.demasson@aphp.fr, Battistella, Maxime⁵ (AUTHOR) maxime.battistella@aphp.fr, Guenova, Emmanuella^6,7 (AUTHOR) emmanuella.guenova@unil.ch, Ribero, Simone² (AUTHOR) pietro.quaglino@unito.it, Quaglino, Pietro² (AUTHOR)

Source: Cells (2073-4409). Feb2025, Vol. 14 Issue 4, p309. 17p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *MYCOSIS fungoides, *SEZARY syndrome, *CANCER cells, *CD26 antigen

Mycosis fungoides and Sézary syndrome – Simplifying the approach for dermatologists. Part 1: Etiopathogenesis, clinical features and evaluation.

Authors: Singh, Gautam Kumar¹ (AUTHOR), Das, Pankaj² (AUTHOR) pankaj3609@gmail.com, Sharma, Pragya³ (AUTHOR), Srivastava, Shailendra⁴ (AUTHOR), Singh, Vikram³ (AUTHOR), Singh, Kanwaljeet⁵ (AUTHOR), Barui, Sanghita⁶ (AUTHOR), Mulajkar, Deepak⁷ (AUTHOR), Dubey, Indra Prakash⁸ (AUTHOR)

Source: Indian Journal of Dermatology, Venereology & Leprology. Jan/Feb2025, Vol. 91 Issue 1, p1-9. 9p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *MYCOSIS fungoides, *SEZARY syndrome, *T cells, *DERMATOLOGISTS

Pharmacological Modulation of the Unfolded Protein Response as a Therapeutic Approach in Cutaneous T-Cell Lymphoma.

Authors: St. Thomas, Nadia¹ (AUTHOR) stthoman@musc.edu, Christopher, Benjamin N.¹ (AUTHOR) christob@musc.edu, Reyes, Leticia¹ (AUTHOR) reyesl@musc.edu, Robinson, Reeder M.¹ (AUTHOR) robinree@musc.edu, Golick, Lena¹ (AUTHOR) golick@musc.edu, Zhu, Xiaoyi² (AUTHOR) xiaoyizhu@ufl.edu, Chapman, Eli² (AUTHOR) chapmaneli@ufl.edu, Dolloff, Nathan G.^1,3,4 (AUTHOR) dolloffn@musc.edu

Source: Biomolecules (2218-273X). Jan2025, Vol. 15 Issue 1, p76. 22p.

Subject Terms: *UNFOLDED protein response, *CUTANEOUS T-cell lymphoma, *GENE regulatory networks, *PATIENT experience, *PROTEASOME inhibitors

Pegylated interferon α-2a in the management of cutaneous T-cell lymphoma.

Authors: Asermouh, Marwa¹ marwasermouh@gmail.com, Khabba, ChaïmaeAït¹, Senouci, Karima¹, Fares, Salma², Hidane, Zakia, Chakiri, Radia³, Benzekri, Laila¹

Source: Our Dermatology Online / Nasza Dermatologia Online. Jan2025, Vol. 16 Issue 1, p72-75. 4p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *MYCOSIS fungoides, *LYMPHOPROLIFERATIVE disorders, *INTERFERON alpha, *INTERFERONS

A retrospective study of prognostic factors and treatment outcome in advanced-stage Mycosis Fungoides and Sezary Syndrome.

Authors: Xu, Zhuo-fan^1,2 (AUTHOR), Chen, Hongyun¹ (AUTHOR), Liu, Yuehua³ (AUTHOR), Zhang, Wei¹ (AUTHOR) vv1223@vip.sina.com, Jin, Hongzhong³ (AUTHOR) jinhongzhong@263.net, Liu, Jie³ (AUTHOR) liujie04672@pumch.cn

Source: Hematology. Dec2024, Vol. 29 Issue 1, p1-9. 9p.

Subject Terms: *PROGRESSION-free survival, *CUTANEOUS T-cell lymphoma, *MYCOSIS fungoides, *PROGNOSIS, *OVERALL survival

Synergistic Activation of VDR-RXR Heterodimers by Vitamin D and Rexinoids in Human Kidney and Brain Cells.

Authors: Doost, Mobin Emran¹ (AUTHOR) medoost@asu.edu, Hong, Jennifer¹ (AUTHOR), Broatch, Jennifer E.¹ (AUTHOR), Applegate, Michael T.¹ (AUTHOR), Wagner, Carl E.¹ (AUTHOR), Marshall, Pamela A.¹ (AUTHOR) pamela.marshall@asu.edu, Jurutka, Peter W.¹ (AUTHOR)

Source: Cells (2073-4409). Nov2024, Vol. 13 Issue 22, p1878. 24p.

Subject Terms: *VITAMIN D receptors, *CUTANEOUS T-cell lymphoma, *LIGANDS (Biochemistry), *GENETIC transcription, *HETERODIMERS

CD4/CD8 double-negative mycosis fungoides: a review.

Authors: Nagshabandi, Khalid Nabil¹, Shadid, Abdulrahman¹, Shadid, Asem¹, Almuhanna, Nouf K.¹

Source: Dermatology Reports. 2024, Vol. 16 Issue 4, p39-42. 4p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *MYCOSIS fungoides, *PROGNOSIS, *IMMUNOLOGIC memory, *SYMPTOMS

Diagnostic Approach to Adult Erythroderma: A Rare Case of Sezary Syndrome.

Authors: Savitri, Quri Meihaerani¹, Rettobyan, Fitria², Astari, Linda², Rahmatika, Amira Suryani, Diansyah, Muhammad Noor³, Amrita, Putu Niken Ayu³, Romadhon, Pradana Zaky³, Bintoro, Sipirianus Ugroseno Yudho^3,4, Ashariati, Ami³, Savitri, Merlyna³ merlyna.savitri@gmail.com

Source: Iranian Journal of Pathology. Fall2024, Vol. 19 Issue 4, p460-466. 7p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *SYMPTOMS, *HOSPITAL admission & discharge, *HEPATITIS B, *SKIN biopsy, *DYSTROPHY

Prevalence, clinical features, and survival outcome trends of 627 patients with primary cutaneous lymphoma over 29 years: a retrospective review from single tertiary center in Korea.

Authors: Moon, Ik Jun¹, Won, Chong Hyun¹, Chang, Sung Eun¹, Park, Chan-Sik², Yoon, Dok-Hyun³, Song, Si Yeol⁴, Lee, Mi Woo¹ miumiu@amc.seoul.kr, Lee, Woo Jin¹ uucm79@hanmail.net

Source: Scientific Reports. 8/29/2024, Vol. 14 Issue 1, p1-9. 9p.

Subject Terms: *SURVIVAL rate, *CUTANEOUS T-cell lymphoma, *T-cell lymphoma, *MUCOSA-associated lymphoid tissue lymphoma, *MYCOSIS fungoides, *B cells

Beyond the pale: Insights into hypopigmented mycosis fungoides -- A case report.

Authors: Zauddin, Nur Zafirah¹ zafirahzauddin@gmail.com, Hadi, Azwanis Abdul¹

Source: Malaysian Family Physician. 8/17/2024, p1-5. 5p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *NON-Hodgkin's lymphoma, *SKIN infections, *MYCOSES, *SKIN biopsy, *SEZARY syndrome

Neurolymphomatosis as primary presentation of extra-nodal NK/T-cell lymphoma, nasal type.

Authors: Silva, Maria Inês¹ (AUTHOR) m.sanches@campus.ul.pt, Santos, Pedro² (AUTHOR), Viegas, Diana² (AUTHOR), Miranda, Miguel¹ (AUTHOR), Montes, Vera¹ (AUTHOR), Pita, Fernando¹ (AUTHOR), Carmona, Cátia¹ (AUTHOR)

Source: Neurological Sciences. Aug2024, Vol. 45 Issue 8, p4003-4006. 4p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *PERIPHERAL nervous system, *MAGNETIC resonance imaging, *POSITRON emission tomography, *LYMPHOMAS, *CENTRAL nervous system

Reverse causation bias: A simulation study comparing first- and second-line treatments with an overlap of symptoms between treatment indication and studied outcome.

Authors: Øland, Christian Bjerregård¹ (AUTHOR) qbodk@leo-pharma.com, Ranch, Lise Skov¹ (AUTHOR), Skaaby, Tea¹ (AUTHOR), Delvin, Thomas¹ (AUTHOR), Jakobsen, Henny Bang¹ (AUTHOR), Pipper, Christian Bressen¹ (AUTHOR)

Source: PLoS ONE. 7/12/2024, Vol. 19 Issue 7, p1-15. 15p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *SYMPTOMS, *PROPORTIONAL hazards models

Dermatological disorders with varioliform scars: A clinical approach.

Authors: Devi Gunasekaran, Anu Kiruba¹ archanasingal@gmail.com, Singal, Archana¹

Source: Indian Journal of Dermatology, Venereology & Leprology. Jul/Aug2024, Vol. 90 Issue 4, p542-548. 7p.

Subject Terms: *MEDICAL sciences, *CUTANEOUS T-cell lymphoma, *SUDDEN onset of disease, *SKIN diseases, *MULTINUCLEATED giant cells, *CHICKENPOX, *DERMATOMYOSITIS

Dermoscopy of nevoid hyperkeratosis of the nipple and/or areola in Fitzpatrick skin type IV.

Authors: Chauhan, Payal¹ (AUTHOR) chauhanpayal89@gmail.com, Dhiman, Avita¹ (AUTHOR), Daroach, Manju¹ (AUTHOR)

Source: Journal of Cutaneous & Aesthetic Surgery. Oct-Dec2024, Vol. 17 Issue 4, p1-3. 3p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *KERATOSIS follicularis, *ACANTHOSIS nigricans, *HUMAN skin color, *HEMATOXYLIN & eosin staining

Cutaneous lymphoproliferative disorders: Back to the future.

Authors: Willemze, Rein¹ (AUTHOR) rein.willemze@planet.nl

Source: Journal of Cutaneous Pathology. Jun2024, Vol. 51 Issue 6, p468-476. 9p.

Subject Terms: *LYMPHOPROLIFERATIVE disorders, *CUTANEOUS T-cell lymphoma, *T-cell receptor genes, *MUCOSA-associated lymphoid tissue lymphoma, *T-cell lymphoma, *KILLER cell receptors, *B cell receptors

Application of Photodynamic Therapy with 5-Aminolevulinic Acid to Extracorporeal Photopheresis in the Treatment of Cutaneous T-Cell Lymphoma: A First-in-Human Phase I/II Study †.

Authors: Christensen, Eidi^1,2,3 (AUTHOR) eidi.christensen@ntnu.no, Foss, Olav Andreas⁴ (AUTHOR) olav.foss@ntnu.no, Holien, Toril^5,6 (AUTHOR) toril.holien@ntnu.no, Juzenas, Petras³ (AUTHOR) qian.peng@rr-research.no, Peng, Qian^3,7 (AUTHOR)

Source: Pharmaceutics. Jun2024, Vol. 16 Issue 6, p815. 12p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *PHOTODYNAMIC therapy, *LEUKOCYTES, *T cells, *TREATMENT effectiveness, *RITUXIMAB

Effects of Body Mass Index on Hypertriglyceridemia Associated with Oral Bexarotene Therapy: A Post Hoc Analysis of an Open-Label Comparative Clinical Study of Combined Bexarotene and Phototherapy Versus Bexarotene Monotherapy for Japanese Patients with Cutaneous T-Cell Lymphoma

Authors: Sanagawa, Akimasa^1,2,3 (AUTHOR) phsanag@med.nagoya-cu.ac.jp, Hayakawa, Tomoaki^1,2 (AUTHOR), Yamamoto, Aya⁴ (AUTHOR), Hotta, Yuji^1,2,3 (AUTHOR), Furukawa-Hibi, Yoko^1,2 (AUTHOR), Morita, Akimichi⁴ (AUTHOR)

Source: Drugs in R&D. Jun2024, Vol. 24 Issue 2, p227-238. 12p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *BODY mass index, *DRUG efficacy, *JAPANESE people, *HYPERTRIGLYCERIDEMIA

The Role of Surgery to Relieve Symptomatic Cutaneous T-Cell Lymphoma Refractory to Medical Treatments.

Authors: Zhang, Wesley Q.¹ (AUTHOR), Hecox, Emily E.² (AUTHOR), Dogar, Shireen² (AUTHOR), Walker, Marc E.² (AUTHOR)

Source: Case Reports in Oncological Medicine. 4/26/2024, Vol. 2024, p1-4. 4p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *MYCOSIS fungoides, *CARPAL tunnel syndrome, *THERAPEUTICS, *HEALTH facilities, *MEDIAN nerve, *MEDICAL care standards

XPO1 blockade with KPT-330 promotes apoptosis in cutaneous T-cell lymphoma by activating the p53–p21 and p27 pathways.

Authors: Chakravarti, Nitin¹ (AUTHOR) nitin.chakravarti@jefferson.edu, Boles, Amy² (AUTHOR), Burzinski, Rachel² (AUTHOR), Sindaco, Paola² (AUTHOR), Isabelle, Colleen² (AUTHOR), McConnell, Kathleen² (AUTHOR), Mishra, Anjali² (AUTHOR), Porcu, Pierluigi³ (AUTHOR) pierluigi.porcu@jefferson.edu

Source: Scientific Reports. 4/23/2024, Vol. 14 Issue 1, p1-12. 12p.

Subject Terms: *CUTANEOUS T-cell lymphoma, *DIFFUSE large B-cell lymphomas, *MULTIPLE myeloma, *HEMATOLOGIC malignancies, *SMALL molecules, *RITUXIMAB