Virus-neutralizing monoclonal antibodies against bovine viral diarrhea virus and classical swine fever virus target conformational and linear epitopes on E2 glycoprotein subdomains

Authors: Gleyder Roman-Sosa, Denise Meyer, Mariano Dellarole, Doris à Wengen, Susanne Lerch, Alexander Postel, Paul Becher

Source: Microbiology Spectrum, Vol 13, Iss 4 (2025)

Subject Terms: classical swine fever virus, bovine viral diarrhea virus, glycoprotein E2, epitope mapping, conformational epitope, virus neutralization, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/1b23e75f93a640aa9e789a0931990129

Allergenicity and Conformational Diversity of Allergens

Authors: Clarissa A. Seidler, Ricarda Zeindl, Monica L. Fernández-Quintero, Martin Tollinger, Klaus R. Liedl

Source: Allergies, Vol 4, Iss 1, Pp 1-16 (2024)

Subject Terms: allergens, IgE, cross-reactivity, pH-dependence, linear epitope, conformational epitope, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2313-5786/4/1/1; https://doaj.org/toc/2313-5786

Access URL: https://doaj.org/article/c72f941c8a144f5d931f280e354894b0

Establishment of novel anti-TIM-3 antibodies interfering with its binding to ligands

Authors: Yan, Zhuohong ^{a, ⁎, 1}, Ma, Teng ^{a, 1}, Wang, Xiaojue ^a, Yi, Ling ^a, Wei, Panjian ^a, Zhang, Hongtao ^a, Wang, Jinghui ^{a, b, ⁎⁎}

Source: In Heliyon 15 April 2024 10(7)

A systematic review: B-cell conformational epitope prediction from epitope characteristics view

Authors: Solihah, Binti, Winarko, Edi, Afiahayati, Hartati, Sri, Wibowo, Moh. Edi

Source: 2017 3rd International Conference on Science and Technology - Computer (ICST) Science and Technology - Computer (ICST), 2017 3rd International Conference on. :93-98 Jul, 2017

Relation: 2017 3rd International Conference on Science and Technology - Computer(ICST)

Computational identification of antibody-binding epitopes from mimotope datasets

Authors: Rang Li, Sabrina Wilderotter, Madison Stoddard, Debra Van Egeren, Arijit Chakravarty, Diane Joseph-McCarthy

Source: Frontiers in Bioinformatics, Vol 4 (2024)

Subject Terms: conformational epitope, mimotopes, structure-based mimotope mapping, antigen-antibody binding-site prediction, immunodiagnostics design, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbinf.2024.1295972/full; https://doaj.org/toc/2673-7647

Access URL: https://doaj.org/article/ea77786d346d4f2ba5cfe2a0a4f4dcb1

Linear Epitope Prediction for Grouper Iridovirus Antigens

Authors: Shih, Tao-Chuan, Pai, Tun-Wen, Ho, Li-Ping, Chou, Hsin-Yiu

Source: 2016 International Computer Symposium (ICS) ICS Computer Symposium (ICS), 2016 International. :50-55 Dec, 2016

Relation: 2016 International Computer Symposium (ICS)

Identification of neutralizing epitopes on the D/A domain of the E2 glycoprotein of classical swine fever virus

Authors: Yu-Liang Huang, Denise Meyer, Alexander Postel, Kuo-Jung Tsai, Hsin-Meng Liu, Chia-Huei Yang, Yu-Chun Huang, Hui-Wen Chang, Ming-Chung Deng, Fun-In Wang, Paul Becher, Helen Crooke, Chia-Yi Chang

Source: Virus Research, Vol 336, Iss , Pp 199209- (2023)

Subject Terms: Classical swine fever virus, Pestivirus, Glycoprotein E2, Epitope mapping, Conformational epitope, Virus neutralization, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0168170223001715; https://doaj.org/toc/1872-7492

Access URL: https://doaj.org/article/d5929ebdc5e04b1198ec1498fceb0bef

A humanized anti-human adenovirus 55 monoclonal antibody with good neutralization ability

Authors: Lei Chen, Jiansheng Lu, Junjie Yue, Rong Wang, Peng Du, Yunzhou Yu, Jiazheng Guo, Xi Wang, Yujia Jiang, Kexuan Cheng, Zhixin Yang, Tao Zheng

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: human adenovirus type 55(HAdV55), monoclonal antibody(mAb), scFv-phage immune library, neutralizing antibody, conformational epitope, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1132822/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/64db3b0972de46978a56bc101c32812d

Combined Immunoinformatics to Design and Evaluate a Multi-Epitope Vaccine Candidate against Streptococcus suis Infection

Authors: Song Liang, Shidan Zhang, Yinli Bao, Yumin Zhang, Xinyi Liu, Huochun Yao, Guangjin Liu

Source: Vaccines, Vol 12, Iss 2, p 137 (2024)

Subject Terms: multi-epitope vaccine, Streptococcus suis, conformational epitope, immunoinformatic, immune protection, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/2/137; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/4d190ab0a22e4062a9ffd1d282e7ede6

Production, characterization, and epitope mapping of monoclonal antibodies of ribosomal protein S3 (rpS3)

Authors: Woo-Sung Ahn, Tae-Sung Kim, Yong Jun Park, Young Kwang Park, Hag Dong Kim, Joon Kim

Source: Animal Cells and Systems, Vol 25, Iss 5, Pp 323-336 (2021)

Subject Terms: ribosomal protein subunit small 3, epitope mapping, mab, peptide synthesis, direct elisa, sandwich elisa, linear form epitope, conformational epitope, immunoprecipitation, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1976-8354; https://doaj.org/toc/2151-2485

Access URL: https://doaj.org/article/c46a4749573c4aa58c8e0328226a2599

Molecular Evolutionary Analyses of the Spike Protein Gene and Spike Protein in the SARS-CoV-2 Omicron Subvariants

Authors: Norika Nagasawa, Ryusuke Kimura, Mao Akagawa, Tatsuya Shirai, Mitsuru Sada, Kaori Okayama, Yuka Sato-Fujimoto, Makoto Saito, Mayumi Kondo, Kazuhiko Katayama, Akihide Ryo, Makoto Kuroda, Hirokazu Kimura

Source: Microorganisms, Vol 11, Iss 9, p 2336 (2023)

Subject Terms: SARS-CoV-2 Omicron subvariants, evolution, spike protein gene, conformational epitope, receptor-binding domain (RBD), vaccine evasion, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/11/9/2336; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/8728f7d88448447f8dd6a77c4d21213d

The Empirical Comparison of Machine Learning Algorithm for the Class Imbalanced Problem in Conformational Epitope Prediction

Authors: Binti Solihah, Azhari Azhari, Aina Musdholifah

Source: Jurnal Informatika, Vol 9, Iss 1, Pp 131-138 (2021)

Subject Terms: sampling-based method, class imbalance, conformational epitope, b-cell, machine learning-based, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: http://jurnalnasional.ump.ac.id/index.php/JUITA/article/view/9969; https://doaj.org/toc/2086-9398; https://doaj.org/toc/2579-8901

Access URL: https://doaj.org/article/6f2d794242f34adc9c7a87c75a25e98c

Functional epitopes on hepatitis E virions and recombinant capsids are highly conformation-dependent

Authors: Bin He, Zhigang Zhang, Xinyuan Zhang, Zimin Tang, Chang Liu, Zizheng Zheng, Shaowei Li, Jun Zhang, Ningshao Xia, Qinjian Zhao

Source: Human Vaccines & Immunotherapeutics, Vol 16, Iss 7, Pp 1554-1564 (2020)

Subject Terms: conformational epitope, functional assessment, hepatitis e virus, hev p239 vaccine, particulate antigen, neutralizing antibody, serological assay, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/fe6f12cea8be4039bb19bc713983e3ce

Ascorbylation of a Reactive Cysteine in the Major Apple Allergen Mal d 1

Authors: Linda Ahammer, Jana Unterhauser, Reiner Eidelpes, Christina Meisenbichler, Bettina Nothegger, Claudia E. Covaciu, Valentina Cova, Anna S. Kamenik, Klaus R. Liedl, Kathrin Breuker, Klaus Eisendle, Norbert Reider, Thomas Letschka, Martin Tollinger

Source: Foods, Vol 11, Iss 19, p 2953 (2022)

Subject Terms: chemical modification, conformational epitope, Malus domestica, nuclear magnetic resonance, protein structure, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://www.mdpi.com/2304-8158/11/19/2953; https://doaj.org/toc/2304-8158

Access URL: https://doaj.org/article/9880b798acf44364809c073ffa64b63f

Conformational Changes of the Receptor Binding Domain of SARS-CoV-2 Spike Protein and Prediction of a B-Cell Antigenic Epitope Using Structural Data

Authors: Sangeeta Khare, Marli Azevedo, Pravin Parajuli, Kuppan Gokulan

Source: Frontiers in Artificial Intelligence, Vol 4 (2021)

Subject Terms: spike protein, SARS–CoV−2, receptor binding domian, conformational epitope, viral infection, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frai.2021.630955/full; https://doaj.org/toc/2624-8212

Access URL: https://doaj.org/article/c43bd3b395494891a854c24718b90248

Molecular Evolution of the Fusion Protein (F) Gene in Human Respirovirus 3

Authors: Jumpei Aso, Hirokazu Kimura, Haruyuki Ishii, Takeshi Saraya, Daisuke Kurai, Yuki Matsushima, Koo Nagasawa, Akihide Ryo, Hajime Takizawa

Source: Frontiers in Microbiology, Vol 10 (2020)

Subject Terms: molecular evolution, human respirovirus 3, fusion protein (F) gene, fusion peptide, conformational epitope, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2019.03054/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/10a35e6898ce4ca1afb44059f472baa7

Identification of a Common Conformational Epitope on the Glycoprotein E2 of Classical Swine Fever Virus and Border Disease Virus

Authors: Yu-Liang Huang, Denise Meyer, Alexander Postel, Kuo-Jung Tsai, Hsin-Meng Liu, Chia-Huei Yang, Yu-Chun Huang, Nicholas Berkley, Ming-Chung Deng, Fun-In Wang, Paul Becher, Helen Crooke, Chia-Yi Chang

Source: Viruses, Vol 13, Iss 8, p 1655 (2021)

Subject Terms: classical swine fever virus, border disease virus, glycoprotein E2, epitope mapping, cross reactivity, conformational epitope, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/13/8/1655; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/a2853d3c86f44e7bb4f8702bec942266

Recognition of Dimeric Lewis X by Anti-Dimeric Lex Antibody SH2

Authors: Sinthuja Jegatheeswaran, Ari Asnani, Adam Forman, Jenifer L. Hendel, Christopher J. Moore, Ali Nejatie, An Wang, Jo-Wen Wang, France-Isabelle Auzanneau

Source: Vaccines, Vol 8, Iss 3, p 538 (2020)

Subject Terms: tumor-associated carbohydrate antigens, ELISA, dimeric Lewis X, SH2, conformational epitope, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/8/3/538; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/12db653e77f640e9acb2e3ea5fd1acd3

idiotype

Source: Library of Health and Living: The Encyclopedia of Autoimmune Diseases.

Availability: https://search.credoreference.com/content/entry/fofad/idiotype/0

Mapping Epitopes and Antigenicity by Site-Directed Masking

Authors: Paus, Didrik, Winter, Greg

Source: Proceedings of the National Academy of Sciences of the United States of America, 2006 Jun . 103(24), 9172-9177.

Access URL: https://www.jstor.org/stable/30051916