The role of the NOTCH1 signaling pathway in the maintenance of mesenchymal stem cell stemness and chondrocyte differentiation and its potential in the treatment of osteoarthritis

Authors: Fuming Wu, Haiquan Yu

Source: Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2025)

Subject Terms: Mesenchymal stem cells, Osteoarthritis, NOTCH1 signaling pathway, EZH2, Chondrocyte differentiation, Endoplasmic reticulum stress, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://doaj.org/toc/1749-799X

Access URL: https://doaj.org/article/1da80be2a3d44850a519e0dc46ebee84

Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis

Authors: Changyuan Huang, Bin Zeng, Bo Zhou, Guanming Chen, Qi Zhang, Wenhong Hou, Guozhi Xiao, Li Duan, Ni Hong, Wenfei Jin

Source: Genes and Diseases, Vol 12, Iss 2, Pp 101241- (2025)

Subject Terms: Cell heterogeneity, Chondrocyte apoptosis, Chondrocyte differentiation, Chondrocyte fibrosis, Osteoarthritis, Single-cell RNA-seq, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304224000382; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/68da3738cd514997aa08c5832dd7aa2e

CDK8 inhibitor KY-065 rescues skeletal abnormalities in achondroplasia model mice

Authors: Sadamori, Koki ^{a, 1}, Kubo, Takuya ^{a, 1}, Yoshida, Tomoki ^b, Yamamoto, Megumi ^c, Shibata, Yui ^c, Fukasawa, Kazuya ^a, Tokumura, Kazuya ^a, Horie, Tetsuhiro ^a, Kadota, Takuya ^a, Yamakawa, Ryotaro ^a, Hojo, Hironori ^{d, e}, Tanaka, Nobutada ^b, Kitao, Tatsuya ^c, Shirahase, Hiroaki ^c, Hinoi, Eiichi ^{a, f, g, ⁎}

Source: In BBA - Molecular Basis of Disease March 2025 1871(3)

Stem Cells in Domestic Animals

Contributors: Iacono, Eleonora, Merlo, Barbara

Subject Terms: canine, reprogramming, iPSCs, VEE RNA, integration-free, stromal vascular fraction, harvest site, adipose-derived MSCs, flow cytometry, One Medicine, mesenchymal stem cells, immune-mediated disorders, ophthalmology, reproduction, equine asthma, equine metabolic syndrome, wounds, laminitis, neurologic disorders, scrapie, prion, sheep, infection, mesenchymal stem cell, in vitro model, canine adipose-derived mesenchymal stem cells (cAD-MSCs), cryopreservation, dimethyl sulfoxide (DMSO), fetal bovine serum (FBS), chicken, culture, disease, probiotics, applications, Camelus dromedarius, bone marrow, synovial fluid, chondrocyte differentiation, dog, foetal adnexa, therapy, platelet lysate, mesenchymal stromal cells (MSC), equine, cell fitness, adhesion, α4β1 integrin, β-lactam agonist, poly L-lactic acid (PLLA) scaffold, stem cells, cell therapy, large animal models, ischemic cardiomyopathies, myocardial infarction, adipose-derived mesenchymal stem cells, stem cell therapy, regenerative veterinary medicine, adipose tissue, olfactory stem cells, isolation, stemness, differentiation, characterization, regenerative medicine, canine mesenchymal stem cells, morphology, phenotype, multilineage potential, bovine, mesenchymal stromal cells, clinical applications, reproductive biotechnologies, Wharton’s jelly, storage, Research and information: general, Biology, life sciences

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Access URL: https://directory.doabooks.org/handle/20.500.12854/96615
https://mdpi.com/books/pdfview/book/6560

A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation

Authors: Shusaku Abe, Hiroaki Nagatomo, Hiroyuki Sasaki, Takashi Ishiuchi

Source: Epigenetics, Vol 16, Iss 10, Pp 1123-1134 (2021)

Subject Terms: histone modification, oncohistone mutation, polycomb complex, chondrocyte differentiation, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/5be4f6b5062b4fd0baaf5383c2f8e329

Targeted Deletion of the Claudin12 Gene in Mice Increases Articular Cartilage and Inhibits Chondrocyte Differentiation

Authors: Weirong Xing, Sheila Pourteymoor, Yian Chen, Subburaman Mohan

Source: Frontiers in Endocrinology, Vol 13 (2022)

Subject Terms: Claudin12, knockout, bone, chondrocyte, cartilage, chondrocyte differentiation, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2022.931318/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/cbdba399f6814996bf65cff0c5c3c037

Collagen-Derived Dipeptide Pro-Hyp Enhanced ATDC5 Chondrocyte Differentiation under Hypoxic Conditions

Authors: Yoshifumi Kimira, Takahiro Sato, Mayu Sakamoto, Yoshihiro Osawa, Hiroshi Mano

Source: Molecules, Vol 28, Iss 12, p 4664 (2023)

Subject Terms: collagen-derived peptide, prolyl-hydroxyproline, chondrocyte differentiation, physiological hypoxic condition, cartilage, extracellular matrix, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/12/4664; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/38cd76ccb1ca41a39a159dfa5ed33862

Neural cell adhesion molecule regulates chondrocyte hypertrophy in chondrogenic differentiation and experimental osteoarthritis

Authors: Bin‐Feng Cheng, Jun‐Jiang Lian, Hai‐Jie Yang, Lei Wang, Hao‐Heng Yu, Jia‐Jia Bi, Yao‐Xin Gao, Su‐Juan Chen, Mian Wang, Zhi‐Wei Feng

Source: Stem Cells Translational Medicine, Vol 9, Iss 2, Pp 273-283 (2020)

Subject Terms: chondrocyte differentiation, chondrocyte hypertrophy, mesenchymal stem cells, NCAM, osteoarthritis, Medicine (General), R5-920, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2157-6564; https://doaj.org/toc/2157-6580

Access URL: https://doaj.org/article/4666f4db9eed450eb8260b35315a0c43

BMP Signaling Stimulates Cellular Differentiation at Multiple Steps During Cartilage Development

Authors: Kobayashi, Tatsuya, Lyons, Karen M., McMahon, Andrew P., Kronenberg, Henry M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Dec . 102(50), 18023-18027.

Access URL: https://www.jstor.org/stable/4152721

Parathyroid Hormone-Related Peptide (PTHrP)-Dependent and-Independent Effects of Transforming Growth Factor β (TGF-β) on Endochondral Bone Formation

Authors: Serra, Rosa, Karaplis, Andrew, Sohn, Philip

Source: The Journal of Cell Biology, 1999 May . 145(4), 783-794.

Access URL: https://www.jstor.org/stable/1619225

Cell Source-Dependent In Vitro Chondrogenic Differentiation Potential of Mesenchymal Stem Cell Established from Bone Marrow and Synovial Fluid of Camelus dromedarius

Authors: Young-Bum Son, Yeon Ik Jeong, Yeon Woo Jeong, Mohammad Shamim Hossein, Per Olof Olsson, Alex Tinson, Kuhad Kuldip Singh, Sang-Yun Lee, Woo Suk Hwang

Source: Animals, Vol 11, Iss 7, p 1918 (2021)

Subject Terms: mesenchymal stem cells, Camelus dromedarius, bone marrow, synovial fluid, chondrocyte differentiation, Veterinary medicine, SF600-1100, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2615/11/7/1918; https://doaj.org/toc/2076-2615

Access URL: https://doaj.org/article/bb78a9e6016543008414d5b1a56b0ee2

Hydroxylation of methylated DNA by TET1 in chondrocyte differentiation of C3H10T1/2 cells

Authors: Ryo Ito, Hiroki Shimada, Kengo Yazawa, Ikuko Sato, Yuuki Imai, Akira Sugawara, Atsushi Yokoyama

Source: Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 134-140 (2016)

Subject Terms: Chondrocyte differentiation, Hydroxymethylcytosine, TET1, Col2, Col10, Igf1, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405580815001296; https://doaj.org/toc/2405-5808

Access URL: https://doaj.org/article/75e6db5d91b8401e9dde9afe7feb3b3e

The signs of differentiation of chondrocytes in the formation of early cartilage lesions in the elderly

Authors: Elena Vasil'evna Chetina, Elena Vasilyevna Chetina

Source: Научно-практическая ревматология, Vol 49, Iss 1, Pp 33-39 (2011)

Subject Terms: articular cartilage, chondrocyte differentiation, gene expression, focal lesions, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://rsp.mediar-press.net/rsp/article/view/998; https://doaj.org/toc/1995-4484; https://doaj.org/toc/1995-4492

Access URL: https://doaj.org/article/a895b4c81a764df08bf7a2d39f201a55

Type II collagen peptide is able to accelerate embryonic chondrocyte differentiation: an association with articular cartilage matrix resorption in osteoarthrosis

Authors: Elena Vasil'evna Chetina, Elena Vasilyevna Chetina

Source: Научно-практическая ревматология, Vol 48, Iss 6, Pp 55-60 (2010)

Subject Terms: growth plate, gene expression, chondrocyte differentiation, type ii collagen peptide, collagenase, Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: https://rsp.mediar-press.net/rsp/article/view/958; https://doaj.org/toc/1995-4484; https://doaj.org/toc/1995-4492

Access URL: https://doaj.org/article/11f0e8daf5b1404ab7c6066f48f39216

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