Hypothesis on the role of cholesterol crystals in spontaneously ruptured aortic plaques: Potential triggers for inflammation and systemic effects

Authors: Chikao Yutani, Hirotaka Noda, Nobuzo Iwa, Sei Komatsu, Satoru Takahashi, Yoshiharu Higuchi, Kazuhisa Kodama

Source: American Heart Journal Plus, Vol 51, Iss , Pp 100507- (2025)

Subject Terms: Innate immunity, Aorta, Spontaneous ruptured aortic plaque, Cholesterol crystals, Angioscopy, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666602225000102; https://doaj.org/toc/2666-6022

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Plaques and Ulcers of Both Lower Limbs: A Quiz

Authors: Qianling Zhang, Sha Lu, Xiqing Li, Liangchun Wang, Jianchi Ma

Source: Acta Dermato-Venereologica, Vol 105 (2025)

Subject Terms: Necrobiotic Xanthogranuloma, cholesterol crystals, tofacitinib, Dermatology, RL1-803

File Description: electronic resource

Relation: https://medicaljournalssweden.se/actadv/article/view/42510; https://doaj.org/toc/0001-5555; https://doaj.org/toc/1651-2057

Access URL: https://doaj.org/article/55d00fca87754804ae96d6221e23025b

Predictive models for cholesterol crystals and plaque vulnerability in acute myocardial infarction: Insights from an optical coherence tomography study

Authors: Deng, Chancui ^{a, 1}, Liu, Zhijiang ^{a, 1}, Li, Chaozhong ^{a, 1}, Xu, Guanxue ^b, Zhang, Renyi ^a, Bai, Zhixun ^a, Hu, Xingwei ^a, Xia, Qianhang ^a, Pan, Li ^a, Wang, Sha ^a, Xia, Jie ^a, Zhao, Ranzun ^{a, ⁎}, Shi, Bei ^{a, ⁎}

Source: In International Journal of Cardiology 1 January 2025 418

Imaging human coronary cholesterol/urate crystals with cross-polarized micro-optical coherence tomography

Authors: Kensuke Nishimiya, Gargi Sharma, Kanwarpal Singh, Osman O. Ahsen, Joseph A. Gardecki, Guillermo J. Tearney

Source: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

Subject Terms: optical coherence tomography, coronary artery disease, cholesterol crystals, gout, uric acid, inflammation, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2024.1433227/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/38311d41d38a4d9bbd02cddcb037dc41

Targeting transcription factor pu.1 for improving neurologic outcomes after spinal cord injury

Authors: Yi Shi, Meige Zheng, Yang Luo, Jianjian Li, Fangru Ouyang, Yuanzhe Zhao, Jingwen Wang, Zhida Ma, Congpeng Meng, Yihui Bi, Li Cheng, Juehua Jing

Source: Frontiers in Neuroscience, Vol 18 (2024)

Subject Terms: spinal cord injury, pu.1, lipid droplet, cholesterol crystals, lipid metabolism, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2024.1418615/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/282d7e08bc434e658266afa936460186

Cholesterol Crystal Dissolution Rate of Serum Predicts Outcomes in Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement

Authors: Baravan Al‐Kassou, Lara Al‐Kassou, Thorsten Mahn, Dieter Lütjohann, Jasmin Shamekhi, Nicola Willemsen, Sven Thomas Niepmann, Stephan Baldus, Malte Kelm, Georg Nickenig, Eicke Latz, Sebastian Zimmer

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 3 (2024)

Subject Terms: calcific aortic stenosis, cholesterol crystal dissolution rate, cholesterol crystals, TAVR, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/8256c019cdd446ceb39c342897b4d23c

The effect of colchicine on cholesterol crystal formation, expansion and morphology: a potential mechanism in atherosclerosis

Authors: Zain Ul Abideen, Dorothy R. Pathak, Rand Sabanci, Megan Manu, George S. Abela

Source: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

Subject Terms: cholesterol crystals, atherosclerosis, colchicine, plaque rupture, cardiovascular events, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2024.1345521/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/13cb816d9028463e903fd2cd08a697cc

Cholesterol crystals induce mechanical trauma, inflammation, and neo-vascularization in solid cancers as in atherosclerosis

Authors: George S. Abela, Venkat R. Katkoori, Dorothy R. Pathak, Harvey L. Bumpers, Monika Leja, Zain ul Abideen, Manel Boumegouas, Daniel Perry, Anas Al-Janadi, James E. Richard, Carlo Barnaba, Ilce G. Medina Meza

Source: American Heart Journal Plus, Vol 35, Iss , Pp 100317- (2023)

Subject Terms: Cancer, Atherosclerosis, Biomarkers, Neovascularization, Cholesterol crystals, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666602223000691; https://doaj.org/toc/2666-6022

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The relationships between cholesterol crystals, NLRP3 inflammasome, and coronary atherosclerotic plaque vulnerability in acute coronary syndrome: An optical coherence tomography study

Authors: Chao Xue, Qizhi Chen, Ling Bian, Zhaofang Yin, Zuojun Xu, Huili Zhang, Qingyong Zhang, Junfeng Zhang, Changqian Wang, Run Du, Li Fan

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Subject Terms: acute coronary syndrome, cholesterol crystals, NLRP3 inflammasome, interleukin (IL)-1β, IL-18, optical coherence tomography, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.905363/full; https://doaj.org/toc/2297-055X

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Detecting Free Cholesterol Crystals in a Patient With Spontaneous Cholesterol Embolization Syndrome

Authors: Sei Komatsu, MD, PhD, Chikao Yutani, MD, PhD, Mitsuhiko Takewa, MD, PhD, Satoru Takahashi, MD, Kazuhisa Kodama, MD, PhD

Source: JACC: Case Reports, Vol 2, Iss 4, Pp 615-618 (2020)

Subject Terms: blue toe, cholesterol crystals, cholesterol embolization syndrome, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666084919306709; https://doaj.org/toc/2666-0849

Access URL: https://doaj.org/article/4e21f0c48cf24ecf93f60fdf5cf4830f

Effect of aspirin on cholesterol crystallization: A potential mechanism for plaque stabilization

Authors: Levi Fry, Andre Lee, Shaza Khan, Kusai Aziz, Ameeth Vedre, George S. Abela

Source: American Heart Journal Plus, Vol 13, Iss , Pp 100083- (2022)

Subject Terms: Aspirin, Cholesterol crystals, Plaque stabilization, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666602221000811; https://doaj.org/toc/2666-6022

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Cholesterol-embolization syndrome: current perspectives

Authors: Ozkok A

Source: Vascular Health and Risk Management, Vol Volume 15, Pp 209-220 (2019)

Subject Terms: Cholesterol embolization syndrome, cholesterol crystals, atherosclerosis, inflammation, autoinflammation, corticosteroids, interleukin-1, NLRP3, colchicine, canakinumab, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.dovepress.com/cholesterol-embolization-syndrome-current-perspectives-peer-reviewed-article-VHRM; https://doaj.org/toc/1178-2048

Access URL: https://doaj.org/article/f49033a9b96d4574a0708c9266a3249a

Cholesterol crystals tubulointerstitial injury during nephrotic syndrome; can be classified as tubular crystallopathy?

Authors: Rachele Del Sordo, Carla Covarelli, Rachele Brugnano, Raffaela Sciri, Guido Bellezza, Martina Mandarano, Angelo Sidoni

Source: Journal of Nephropathology, Vol 10, Iss 2, Pp e20-e20 (2021)

Subject Terms: nephrotic syndrome, cholesterol crystals, tubulointerstitial injury, tubular crystallopathy, glomerulonephritis, chronic kidney injury, Pathology, RB1-214, Internal medicine, RC31-1245, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://nephropathol.com/PDF/jnp-10-e20.pdf; https://doaj.org/toc/2251-8363; https://doaj.org/toc/2251-8819

Access URL: https://doaj.org/article/b876992f7af04136a6195514e9b870cd

Micro Optical Coherence Tomography for Coronary Imaging

Authors: Kensuke Nishimiya, Guillermo Tearney

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: optical coherence tomography, micro-OCT, endothelial cells, inflammatory cells, macrophage—cell, cholesterol crystals, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.613400/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/9de8671c0cbc449e955aaab09637c09c

Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis

Authors: Nathalie Niyonzima, Siril S. Bakke, Ida Gregersen, Sverre Holm, Øystein Sandanger, Hilde L. Orrem, Bjørnar Sporsheim, Liv Ryan, Xiang Yi Kong, Tuva Børresdatter Dahl, Mona Skjelland, Kirsten Krohg Sørensen, Anne Mari Rokstad, Arne Yndestad, Eicke Latz, Lars Gullestad, Geir Ø. Andersen, Jan Kristian Damås, Pål Aukrust, Tom E. Mollnes, Bente Halvorsen, Terje Espevik

Source: EBioMedicine, Vol 60, Iss , Pp 102985- (2020)

Subject Terms: Cholesterol crystals, Complement system, NLRP3 inflammasome, Coronary artery disease, Carotid atherosclerosis, Atherosclerosis, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396420303613; https://doaj.org/toc/2352-3964

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Cholesterol Crystals and NLRP3 Mediated Inflammation in the Uterine Wall Decidua in Normal and Preeclamptic Pregnancies

Authors: Gabriela Brettas Silva, Lobke Marijn Gierman, Johanne Johnsen Rakner, Guro Sannerud Stødle, Siv Boon Mundal, Astrid Josefin Thaning, Bjørnar Sporsheim, Mattijs Elschot, Karin Collett, Line Bjørge, Marie Hjelmseth Aune, Liv Cecilie Vestrheim Thomsen, Ann-Charlotte Iversen

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: cholesterol crystals, decidua, fetal growth restriction, NLRP3 inflammasome, inflammation, IL-1β, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.564712/full; https://doaj.org/toc/1664-3224

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Acalculous Cholecystitis Complicated by Liver Abscess as a Manifestation of Cholesterol Embolization Syndrome – Infrequent Manifestation Precipitated by a Common Procedure

Authors: Ossama Maadarani, Hany Alfayed, Zouheir Bitar, Moataz Daher, Tamer Zaalouk, Mohamed Abdelfatah

Source: European Journal of Case Reports in Internal Medicine (2020)

Subject Terms: cholesterol crystals, acalculous cholecystitis, liver abscess, Medicine

File Description: electronic resource

Relation: https://www.ejcrim.com/index.php/EJCRIM/article/view/1953; https://doaj.org/toc/2284-2594

Access URL: https://doaj.org/article/4f554fa321274d059f1687e300643eaa

Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions

Authors: Abdul Muneer, P.M. ^{a, b}, Alikunju, Saleena ^b, Mishra, Vikas ^{a, b}, Schuetz, Heather ^b, Szlachetka, Adam M. ^b, Burnham, Ellen L. ^c, Haorah, James ^{a, b, ⁎}

Source: In Brain Behavior and Immunity May 2017 62:291-305

Atheroembolic kidney disease: The under‐recognized silent killer

Authors: Gabriel Ștefan, Adrian Zugravu, Simona Stancu, Mihaela Gherghiceanu, George Terinte‐Balcan

Source: Clinical Case Reports, Vol 9, Iss 3, Pp 1824-1825 (2021)

Subject Terms: atheroembolic kidney disease, blue toe, cholesterol crystals, livedo reticularis, systemic atherosclerosis, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0904

Access URL: https://doaj.org/article/551d8842f77f4285a9da25233a824f90

Acute Myocardial Infarction Caused by Distal Embolization From a Proximal Ruptured Plaque

Authors: Sei Komatsu, MD, PhD, Chikao Yutani, MD, PhD, Satoru Takahashi, MD, Kazuhisa Kodama, MD, PhD

Source: JACC: Case Reports, Vol 2, Iss 1, Pp 33-34 (2020)

Subject Terms: acute coronary syndrome, cholesterol crystals, coronary artery, nonobstructive general angioscopy, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666084919305777; https://doaj.org/toc/2666-0849

Access URL: https://doaj.org/article/061ad1eaf6bc4633a529d7df28a9aaed