Computational Development of Transmission-Blocking Vaccine Candidates Based on Fused Antigens of Pre- and Post-fertilization Gametocytes Against Plasmodium falciparum.

Authors: Adeleke, Matthew A.¹ (AUTHOR) adelekem@ukzn.ac.za

Source: Bioinformatics & Biology Insights. 3/3/2025, p1-22. 22p.

Subject Terms: *CHOLERA toxin, *MOLECULAR dynamics, *PLASMODIUM falciparum, *SALMONELLA enterica, *PLASMODIUM

Challenges and strategies in the soluble expression of CTA1-(S14P5)4-DD and CTA1-(S21P2)4-DD fusion proteins as candidates for COVID-19 intranasal vaccines.

Authors: Tarigan, Simson¹ (AUTHOR) sitariganta@gmail.com, Sekarmila, Gita¹ (AUTHOR), Apas¹ (AUTHOR), Sumarningsih¹ (AUTHOR), Tarigan, Ronald² (AUTHOR), Putri, Riyandini¹ (AUTHOR), Setyawati, Damai Ria¹ (AUTHOR)

Source: PLoS ONE. 12/26/2024, Vol. 19 Issue 12, p1-17. 17p.

Subject Terms: *CHIMERIC proteins, *CHOLERA toxin, *CATALYTIC domains, *VACCINE development, *COVID-19 vaccines

Administration of novobiocin and apomorphine mitigates cholera toxin mediated cellular toxicity: Lessons from cholera toxin yeast model system.

Authors: Bhalerao, Sonali Eknath¹ (AUTHOR), Sen, Himanshu^1,2 (AUTHOR), Raychaudhuri, Saumya^1,2 (AUTHOR) saumya@rocketmail.com

Source: PLoS ONE. 12/5/2024, Vol. 19 Issue 12, p1-14. 14p.

Subject Terms: *CHOLERA toxin, *SMALL molecules, *PARKINSON'S disease, *ADP-ribosylation, DEVELOPING countries

Environmental Vibrio cholerae Strains Harboring Cholera Toxin and Vibrio Pathogenicity Island 1, Nigeria, 2008-2015.

Authors: Morgado, Sergio¹ sergio.morgado@ioc.fiocruz.br, Adewale, Akinsinde², Abiodun, Iwalokun², Lawal, Salako², Freitas, Fernanda¹, Fonseca, Érica¹, Carolina Vicente, Ana¹

Source: Emerging Infectious Diseases. Nov2024, Vol. 30 Issue 11, p2441-2444. 4p.

Subject Terms: *CHOLERA toxin, *VIBRIO cholerae, *CHOLERA

Geographic Terms: NIGERIA

Orbitofrontal cortex to dorsal striatum circuit is critical for incubation of oxycodone craving after forced abstinence.

Authors: Lin, Hongyu¹ (AUTHOR), Olaniran, Adedayo¹ (AUTHOR), Luo, Xiang¹ (AUTHOR), Strauch, Jessica¹ (AUTHOR), Burke, Megan A. M.¹ (AUTHOR), Matheson, Chloe L.^1,2 (AUTHOR), Li, Xuan^1,2 (AUTHOR) annali@umd.edu

Source: Addiction Biology. Oct2024, Vol. 29 Issue 10, p1-16. 16p.

Subject Terms: *PREFRONTAL cortex, *CHOLERA toxin, *OPIOID abuse, *DOPAMINE receptors, *OXYCODONE

Vibrio mimicus Lineage Carrying Cholera Toxin and Vibrio Pathogenicity Island, United States and China.

Authors: Morgado, Sergio Mascarenhas¹ sergio.morgado@ioc.fiocruz.br, dos Santos Freitas, Fernanda¹, Lourenço da Fonseca, Erica¹, Paulo Vicente, Ana Carolina¹

Source: Emerging Infectious Diseases. Aug2024, Vol. 30 Issue 8, p1729-1732. 4p.

Subject Terms: *CHOLERA toxin, *VIBRIO cholerae, *VIBRIO, *GENOMICS, CHINA-United States relations

Geographic Terms: CHINA, UNITED States

Marked enhancement of the immunogenicity of plant‐expressed IgG‐Fc fusion proteins by inclusion of cholera toxin non‐toxic B subunit within the single polypeptide.

Authors: Kim, Mi‐Young^1,2 (AUTHOR), Vergara, Emil² (AUTHOR), Tran, Andy² (AUTHOR), Paul, Matthew John² (AUTHOR), Kwon, Tae‐Ho³ (AUTHOR), Ma, Julian K.C.² (AUTHOR), Jang, Yong‐Suk¹ (AUTHOR) yongsuk@jbnu.ac.kr, Reljic, Rajko² (AUTHOR) rreljic@sgul.ac.uk

Source: Plant Biotechnology Journal. May2024, Vol. 22 Issue 5, p1402-1416. 15p.

Subject Terms: *CHOLERA toxin, *CHIMERIC proteins, *IMMUNE response, *ANTIGEN presenting cells, *VIRAL proteins, *TOXINS, *VIRAL envelope proteins

Investigation of potentially pathogenic Vibrionaceae in Saint-Louis city, Senegal.

Authors: Lo, Seynabou^1,2, Ba, Bissoume Sambe³, Niang, Aissatou Ahmet^4,5, N'diaye, Issa³, Diop, Mamadou¹, De Magny, Guillaume Constantin^3,6,7 guillaume.demagny@ird.fr

Source: Pan African Medical Journal. May-Aug2024, Vol. 48, p1-11. 11p.

Subject Terms: *CHOLERA toxin, *PATHOGENIC bacteria, *VIBRIONACEAE, *BACTERIAL colonies, *BACTERIAL cultures, *VIBRIO cholerae

Mucosal immunization with the lung Lactobacillus-derived amphiphilic exopolysaccharide adjuvanted recombinant vaccine improved protection against P. aeruginosa infection.

Authors: Zhang, Haochi^1,2, Sheng, Shouxin¹, Li, Chunhe¹, Bao, Xuemei¹, Zhao, Lixia², Chen, Jian^1,2, Guan, Pingyuan², Li, Xiaoyan², Pan, Na¹, Liang, Yanchen¹, Wang, Xueqi¹, Sun, Jingmin¹, Wang, Xiao¹, wangxiao@imu.edu.cn

Source: PLoS Pathogens; 11/18/2024, Vol. 20 Issue 11, p1-29, 29p

The Mutagenic Plasticity of the Cholera Toxin B-Subunit Surface Residues: Stability and Affinity.

Authors: Au, Cheuk W.¹ (AUTHOR), Manfield, Iain^1,2 (AUTHOR), Webb, Michael E.^2,3 (AUTHOR), Paci, Emanuele⁴ (AUTHOR), Turnbull, W. Bruce^2,3 (AUTHOR), Ross, James F.^1,2 (AUTHOR) j.f.ross@leeds.ac.uk

Source: Toxins. Mar2024, Vol. 16 Issue 3, p133. 16p.

Subject Terms: *CHOLERA toxin, *SURFACE stability, *ISOTHERMAL titration calorimetry, *PROTEIN stability, *MUTAGENS, *NANOBIOTECHNOLOGY, *CELL membranes

Vibrio cholerae virulence and its suppression through the quorum-sensing system.

Authors: Sajeevan, Anusree¹ (AUTHOR), Ramamurthy, Thandavarayan² (AUTHOR), Solomon, Adline Princy¹ (AUTHOR) adlineprinzy@sastra.ac.in

Source: Critical Reviews in Microbiology. Feb2025, Vol. 51 Issue 1, p22-43. 22p.

Subject Terms: *CHOLERA toxin, *VIBRIO cholerae, *RESOURCE-limited settings, *HUMAN ecology, *CHOLERA, *QUORUM sensing

Design and computational analysis of an effective multi-epitope vaccine candidate using subunit B of cholera toxin as a build-in adjuvant against urinary tract infections.

Authors: Rezaei, Maryam¹, Habibi, Mehri¹, Ehsani, Parastoo¹, Asadi Karam, Mohammad Reza¹ m_asadi12@yahoo.com, Bouzari, Saeid¹ saeidbouzari@yahoo.com

Source: BioImpacts. Jan2024, Vol. 14 Issue 1, p1-13. 13p.

Subject Terms: *CHOLERA toxin, *URINARY tract infections, *VACCINE effectiveness, *VACCINE immunogenicity, *TERTIARY structure, *VACCINE development

Detection of Cholera Toxin in Culture Medium by Dot-Immunoassay on Dipsticks.

Authors: Boyko, A. V.¹ (AUTHOR) rusrapi@microbe.ru, Mikheeva, E. A.¹ (AUTHOR), Zakharova, T. L.¹ (AUTHOR), Osina, N. A.¹ (AUTHOR)

Source: Applied Biochemistry & Microbiology. Dec2023, Vol. 59 Issue 8, p1113-1117. 5p.

Subject Terms: *CHOLERA toxin, *VIBRIO cholerae, *MONOCLONAL antibodies, *TOXINS

Development of Heterologous Expression System and Optimization of the Method of Cholera Toxin β-Subunit Production in E. coli.

Authors: Jamgochian, Hamesd H.¹ (AUTHOR), Zamakhaev, Mikhail V.¹ (AUTHOR), Sluchanko, Nikolai N.¹ (AUTHOR), Goncharenko, Anna V.¹ (AUTHOR) pylaevanna@gmail.com, Shumkov, Mikhail S.¹ (AUTHOR)

Source: Biochemistry (00062979). Sep2023, Vol. 88 Issue 9, p1304-1317. 14p.

Subject Terms: *ESCHERICHIA coli, *CHOLERA toxin, *MATHEMATICAL optimization, *RECOMBINANT proteins, *TOXINS, *AFFINITY chromatography, *GABA receptors

Expression of Cholera Toxin (CT) and the Toxin Co-Regulated Pilus (TCP) by Variants of ToxT in Vibrio cholerae Strains.

Authors: Lee, Donghyun^1,2 (AUTHOR), Choi, Hunseok^1,2 (AUTHOR), Son, Seonghyeon^1,2 (AUTHOR), Bae, Jonghyun^1,2 (AUTHOR), Joo, Jayun^1,2 (AUTHOR), Kim, Dong Wook^1,2 (AUTHOR) dongwook@hanyang.ac.kr, Kim, Eun Jin^1,2 (AUTHOR) dongwook@hanyang.ac.kr

Source: Toxins. Aug2023, Vol. 15 Issue 8, p507. 14p.

Subject Terms: *CHOLERA toxin, *GENE expression, *VIBRIO cholerae, *GENETIC regulation, *TOXINS

The Functions of Cholera Toxin Subunit B as a Modulator of Silica Nanoparticle Endocytosis.

Authors: Susnik, Eva¹ (AUTHOR) eva.susnik@unifr.ch, Balog, Sandor¹ (AUTHOR) sandor.balog@unifr.ch, Taladriz-Blanco, Patricia² (AUTHOR) patricia.taladriz@inl.int, Petri-Fink, Alke^1,3 (AUTHOR) alke.fink@unifr.ch, Rothen-Rutishauser, Barbara¹ (AUTHOR) barbara.rothen@unifr.ch

Source: Toxins. Aug2023, Vol. 15 Issue 8, p482. 16p.

Subject Terms: *CHOLERA toxin, *NANOPARTICLES, *ENDOCYTOSIS, *CELL physiology, *EPITHELIAL cells

Hypothalamic cerebrospinal fluid‐contacting neurons project to the rostral agranular insular cortex: An immunofluorescence and ultrastructural analysis in the rat.

Authors: Martínez‐Lorenzana, Guadalupe¹ (AUTHOR), Gamal‐Eltrabily, Mohammed^2,3 (AUTHOR), Palma‐Tirado, Lourdes⁴ (AUTHOR), González‐Hernández, Abimael¹ (AUTHOR), Condés‐Lara, Miguel¹ (AUTHOR) condes@unam.mx

Source: European Journal of Neuroscience. Nov2024, Vol. 60 Issue 9, p6222-6236. 15p.

Subject Terms: *CHOLERA toxin, *OXYTOCIN receptors, *PARAVENTRICULAR nucleus, *OXYTOCIN, *TRANSMISSION electron microscopy, *HYPOTHALAMUS

Characterization and utility of two monoclonal antibodies to cholera toxin B subunit.

Authors: Verjan Garcia, Noel¹ (AUTHOR), Santisteban Celis, Ian Carlosalberto² (AUTHOR), Dent, Matthew³ (AUTHOR), Matoba, Nobuyuki^1,2,3 (AUTHOR) n.matoba@louisville.edu

Source: Scientific Reports. 3/15/2023, Vol. 13 Issue 1, p1-14. 14p.

Subject Terms: *CHOLERA toxin, *MONOCLONAL antibodies, *CYCLIC adenylic acid, *SURFACE plasmon resonance, *ORAL drug administration, *EPITHELIAL cells

Engineered selective biotoxin‐binding hydrogels for toxin sequestration.

Authors: Morris, Melody A.¹ (AUTHOR), Yang, Yun Jung¹ (AUTHOR), Mai, Danielle J.¹ (AUTHOR), Olsen, Bradley D.¹ (AUTHOR) bdolsen@mit.edu

Source: Journal of Separation Science. Aug2024, Vol. 47 Issue 16, p3861-3869. 9p.

Subject Terms: *CHOLERA toxin, *CARRIER proteins, *ELASTIC solids, *BIOMACROMOLECULES, *NEUTRON scattering

B-Cell Epitope Mapping of the Vibrio cholera Toxins A, B, and P and an ELISA Assay.

Authors: De-Simone, Salvatore G.^1,2,3 (AUTHOR) dsimone@cdts.fiocruz.br, Napoleão-Pêgo, Paloma^1,2 (AUTHOR), Gonçalves, Priscilla S.^1,2,3 (AUTHOR), Lechuga, Guilherme C.^1,2 (AUTHOR), Cardoso, Sergian V.⁴ (AUTHOR), Provance Jr., David W.^1,2 (AUTHOR), Morel, Carlos M.¹ (AUTHOR), da Silva, Flavio R.^1,2 (AUTHOR)

Source: International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 1, p531. 13p.

Subject Terms: *CHOLERA toxin, *B cells, *VIBRIO cholerae, *PEPTIDES, *ENZYME-linked immunosorbent assay, *SERODIAGNOSIS, *B cell receptors