α-Bisabolol alleviates doxorubicin-induced cognitive dysfunction in rats via enhancing the hippocampal BDNF/TrKB signaling and inhibiting neuroinflammation

Authors: Sara T. Elazab, Walter H. Hsu

Source: Frontiers in Pharmacology, Vol 16 (2025)

Subject Terms: chemobrain, cognitive impairment, doxorubicin, α-bisabolol, oxidative stress, BDNF/TrKB signaling, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2025.1549009/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/44fb2f39f903460fa858a173ff3803ac

Longitudinal study of cognitive and mental functions among adult Hodgkin-lymphoma survivors, based on data from a primary treatment center in Hungary

Authors: István Virga, Karolina Kósa, Anna Illés, Zsófia Miltényi, Tibor Ivánka, Roland Berecz, Anikó Égerházi, Árpád Illés, Ferenc Magyari

Source: Frontiers in Oncology, Vol 15 (2025)

Subject Terms: Hodgkin-lymphoma, cancer-related cognitive impairment (CRCI), computerized neuropsychological test battery (CANTAB), health-related quality of life, chemobrain, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2025.1509424/full; https://doaj.org/toc/2234-943X

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Dynamin-1 is a potential mediator in cancer-related cognitive impairment

Authors: Ding Quan Ng, Casey Hudson, Tracy Nguyen, Sukesh Kumar Gupta, Yong Qin Koh, Munjal M. Acharya, Alexandre Chan

Source: Neurotherapeutics, Vol 22, Iss 1, Pp e00480- (2025)

Subject Terms: Cancer-related cognitive impairment, Chemobrain, Dynamin-1, Extracellular vesicle, Exosome, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1878747924001673; https://doaj.org/toc/1878-7479

Access URL: https://doaj.org/article/db9c7caa305e4f8e8a5290b47ce94a4f

Cancer-related cognitive impairment and hippocampal functioning: The role of dynamin-1

Authors: Barbara Johanne Thomas Nordhjem, Lisa Lyngsie Hjalgrim

Source: Neurotherapeutics, Vol 22, Iss 1, Pp e00508- (2025)

Subject Terms: Cancer-related cognitive impairment, Chemobrain, Hippocampus, Memory, Dynamin-1, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1878747924001958; https://doaj.org/toc/1878-7479

Access URL: https://doaj.org/article/2734d88347bd4725b8ae23b5f22fe58d

Toward better understanding and management of chemobrain: the potential utilities of the MemTrax memory test

Authors: Yun Ma, Wenying Chai, Deyong Bu, Xuemin Feng, J. Wesson Ashford, Limei He, Ying Zheng, Curtis B. Ashford, Feng Li, Jun Li, Yuan Dong, Shumo Li, Xianbo Zhou

Source: BMC Women's Health, Vol 24, Iss 1, Pp 1-7 (2024)

Subject Terms: MemTrax memory test, Breast cancer, Chemobrain, Gynecology and obstetrics, RG1-991, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6874

Access URL: https://doaj.org/article/f4c3fc06f50e47caa5e36173454f3f8f

Neuromodulatory effect of troxerutin against doxorubicin and cyclophosphamide-induced cognitive impairment in rats: Potential crosstalk between gut–brain and NLRP3 inflammasome axes

Authors: Gamal, Nada K. ^a, El-Naga, Reem N. ^a, Ayoub, Iriny M. ^b, George, Mina Y. ^{a, ⁎}

Source: In International Immunopharmacology 6 March 2025 149

Changes in cognition and astrocytic reactivity in a female rodent model of chemotherapy-induced cognitive impairment are variable both acutely and chronically

Authors: Haller, Olivia J. ^{a, 1, ⁎}, Semendric, Ines ^{a, 1}, Collins-Praino, Lyndsey E. ^a, Whittaker, Alexandra L. ^b, George, Rebecca P. ^{a, b}

Source: In Behavioural Brain Research 5 March 2025 480

In silico and In vivo protective effect of biochanin-A mitigating doxorubicin- induced cognitive deficits and neuroinflammation: Insights to the role of p-Tau and miR-132

Authors: Hussein, Sarah A. ^a, Tolba, Mai F. ^{a, b}, Michel, Haidy E. ^b, Albohy, Amgad ^{c, d}, Azab, Samar S. ^{b, ⁎, 1}

Source: In Neurotoxicology March 2025 107:22-36

Roflumilast attenuates doxorubicin and cyclophosphamide combination-induced chemobrain in rats through modulation of NLRP3/ASC/caspase-1/GSDMD axis

Authors: Eskander, Georgette ^a, Abdelhamid, Sherihan G. ^b, Wahdan, Sara A. ^c, Radwan, Sara M. ^{b, ⁎}

Source: In Life Sciences 1 February 2025 362

MRI Voxel Morphometry Shows Brain Volume Changes in Breast Cancer Survivors: Implications for Treatment

Authors: Alexandra Nikolaeva, Maria Pospelova, Varvara Krasnikova, Albina Makhanova, Samvel Tonyan, Aleksandr Efimtsev, Anatoliy Levchuk, Gennadiy Trufanov, Mark Voynov, Matvey Sklyarenko, Konstantin Samochernykh, Tatyana Alekseeva, Stephanie E. Combs, Maxim Shevtsov

Source: Pathophysiology, Vol 32, Iss 1, p 11 (2025)

Subject Terms: breast cancer, breast cancer survivors, «chemobrain», brain morphometry, magnetic resonance imaging, voxel morphometry, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.mdpi.com/1873-149X/32/1/11; https://doaj.org/toc/1873-149X

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Cancer-Related Cognitive Impairments (CRCIs) in Non-Central Nervous System Adult Patients: Outcome Measures and Methodology of Assessment: A Literature Review

Authors: Andrea Pace, Antonio Tanzilli, Enrico Marchioni, Alessia Pellerino, Antonino Carmelo Tralongo, Paola Bini, Paolo Tralongo, Stefano Francesco Cappa

Source: Brain Sciences, Vol 14, Iss 11, p 1119 (2024)

Subject Terms: cognitive deficit, survivorship, neurotoxicity, chemobrain, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/14/11/1119; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/55ef09d00aac422484959c2b984ca859

Doxorubicin-induced neurotoxicity differently affects the hippocampal formation subregions in adult mice

Authors: Dias-Carvalho, Ana ^{a, b, ⁎⁎}, Ferreira, Mariana ^{a, b, c}, Reis-Mendes, Ana ^{a, b}, Ferreira, Rita ^c, de Lourdes Bastos, Maria ^{a, b}, Fernandes, Eduarda ^d, Sá, Susana Isabel ^{e, f}, Capela, João Paulo ^{a, b, g}, Carvalho, Félix ^{a, b}, Costa, Vera Marisa ^{a, b, ⁎}

Source: In Heliyon 15 June 2024 10(11)

Chemotherapy and cognitive function: comprehensive review on methotrexate‐induced chemobrain

Authors: Nadine C. Sabry, Haidy E. Michel, Esther T. Menze

Source: Archives of Pharmaceutical Sciences Ain Shams University, Vol 7, Iss 2, Pp 402-420 (2023)

Subject Terms: chemobrain, methotrexate, chemotherapy, cognition, neuroprotection, hippocampus., Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://aps.journals.ekb.eg/article_329481.html; https://doaj.org/toc/2356-8380; https://doaj.org/toc/2356-8399

Access URL: https://doaj.org/article/2e2a046f61e44c1e9960d8b7add98df2

Association of Circulating Levels of Inflammatory Cytokines and Chemotherapy-Associated Subjective Cognitive Impairment in a South African Cohort of Breast Cancer Patients

Authors: Nicholas Keetile, Elzbieta Osuch, Antonio G. Lentoor, Tsakani Rasakanya

Source: NeuroSci, Vol 4, Iss 4, Pp 296-304 (2023)

Subject Terms: chemotherapy, breast cancer, cognitive impairment, chemobrain, neuroinflammation, cytokines, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2673-4087/4/4/24; https://doaj.org/toc/2673-4087

Access URL: https://doaj.org/article/126478dd495e432f9ee45d2fe67fdb9e

Cancer related cognitive impairment: a downside of cancer treatment

Authors: Kimberly Demos-Davies, Jessica Lawrence, Davis Seelig

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: cancer related cognitive impairment, CRCI, cancer treatment, chemobrain, neurobehavior, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1387251/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/7d456c01b25440c082195ac48bd118b9

Diosmin alleviates doxorubicin-induced chemobrain in rats via inhibition of oxido-inflammation, apoptosis and modulation of autophagy

Authors: Oyovwi O. Mega, Falajiki Y. Faith, Ohwin P. Ejiro, Joseph G. Uchechukwu, Olowe G. Temitope, Onome B. Oghenetega, Emojevwe Victor, Tesi P. Edesiri, Rotu A. Rume, Rotu A. Rotu, Oyeleke Abiodun Abioye, Okwute Patrick Godwin

Source: Brain Disorders, Vol 13, Iss , Pp 100111- (2024)

Subject Terms: Chemobrain, Diosmin, Doxorubicin, Inflammation, Oxidative stress, Autophagic flux, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666459323000483; https://doaj.org/toc/2666-4593

Access URL: https://doaj.org/article/bc3cb7086ad8461cbb02766ebb5c7b98

Nasal administration of mesenchymal stem cells prevents accelerated age-related tauopathy after chemotherapy in mice

Authors: Miriam Zamorano, Jenolyn F. Alexander, Desiree Catania, Shruti Dharmaraj, Annemieke Kavelaars, Cobi J. Heijnen

Source: Immunity & Ageing, Vol 20, Iss 1, Pp 1-18 (2023)

Subject Terms: chemobrain, accelerated aging, cellular therapy, regenerative medicine, cancer treatment, chemotherapy, Immunologic diseases. Allergy, RC581-607, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/1742-4933

Access URL: https://doaj.org/article/fefcbd1c7c8f45ca871d07b0cc6694ed

An update on neurobiological mechanisms involved in the development of chemotherapy-induced cognitive impairment (CICI)

Authors: Laura Catalina Murillo, Jhon Jairo Sutachan, Sonia Luz Albarracín

Source: Toxicology Reports, Vol 10, Iss , Pp 544-553 (2023)

Subject Terms: Chemobrain, Cognitive impairment, Neurotoxicity, Chemotherapy drugs, CICI, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214750023000513; https://doaj.org/toc/2214-7500

Access URL: https://doaj.org/article/78ca7d8ac0e54c97802870481f4663af

Chemical characterization of the polyphenolic rich fraction of Thunbergia erecta and its therapeutic potential against doxorubicin and cyclophosphamide-induced cognitive impairment in rats

Authors: El-Din, Mariam I. Gamal ^a, George, Mina Y. ^{b, ∗∗}, Youssef, Fadia S. ^{a, ∗}

Source: In Journal of Ethnopharmacology 10 May 2023 307

The selective cyclooxygenase-2 inhibitor NS398 ameliorates cisplatin-induced impairments in mitochondrial and cognitive function

Authors: Mohammad Abdur Rashid, Jason J. Tang, Ki-Hyun Yoo, Ana Corujo-Ramirez, Alfredo Oliveros, Sang Hoon Kim, Faheem Ullah, Raad Altawell, John R. Hawse, Peter D. Cole, Mi-Hyeon Jang

Source: Frontiers in Molecular Neuroscience, Vol 16 (2023)

Subject Terms: chemobrain, cisplatin, cyclooxygenase-2, NS398, mitochondria, cognitive impairment, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2023.1295991/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/2e8a00bc8a824f1c868666a021f4f0a5