Unveiling the future of cancer stem cell therapy: a narrative exploration of emerging innovations

Authors: Joseph Nhyira Obisi, Abike Ndidiamaka Josephine Abimbola, Oluwasegun Adesina Babaleye, Peter Kwame Atidoglo, Saviour God’swealth Usin, Eudora Obioma Nwanaforo, Faith Sutu Patrick-Inezi, Ilemobayo Victor Fasogbon, Joseph Chimezie, Christianah Adebimpe Dare, Oluwadoyinsayemi Oluwadamilare Kuti, Daniel Ejim Uti, Humphrey Chukwudi Omeoga

Source: Discover Oncology, Vol 16, Iss 1, Pp 1-23 (2025)

Subject Terms: Cancer stem cells (CSCs), Tumour initiation and progression, Chemotherapeutic drug resistance, CAR T-cell therapy, Nanoparticular drug delivery, Gene editing methods, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2730-6011

Access URL: https://doaj.org/article/5ad60c35619c4bb4bf0f8fc05c41f8fd

Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT)

Authors: Chantel P. J. Rice, Vipin Shankar Chelakkot, Noah T. Conohan, Kensuke Hirasawa

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025)

Subject Terms: 5-aminolevulinic acid (5-ALA), Photodynamic therapy (PDT), Cancer stem cells (CSCs), CD133, 5-ALA-PDT resistance, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e575c89b696544f1a6a02a1b167f189f

Unraveling the underlying mechanisms of cancer stem cells in therapeutic resistance for optimizing treatment strategies

Authors: Yunhan Tan, Siyuan Qin, Zhe Zhang, Yongen Liu, Li Zhou, Bowen Li, Edouard C. Nice, Yuanyuan Zhang, Jing Jing

Source: MedComm – Oncology, Vol 4, Iss 1, Pp n/a-n/a (2025)

Subject Terms: cancer stem cells (CSCs), combination therapy, CSC‐targeted therapy, drug resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2769-6448

Access URL: https://doaj.org/article/5f575703db714ecbb80faa998e8475cd

Editorial: Improving stem cell transplantation delivery using computational modelling

Authors: Pawan Kumar Raghav

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: Hematopoietic stem cells (HSCs), HSC transplantation (HSCT), regenerative medicine, cancer stem cells (CSCs), immunomodulation, graft-versus-host disease (GVHD), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1579353/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ae992119032c4628a83f3de9fabe436b

Hypoxia-driven mobilization of altruistic cancer stem cells in platinum-treated head and neck cancer

Authors: Lekhika Pathak, Bidisha Pal, Joyeeta Talukdar, Partha Jyoti Saikia, Sorra Sandhya, Wale Tasabehji, Hong Li, Jyotirmoy Phukan, Anjan Bhuyan, Sanjukta Patra, Bikul Das

Source: Frontiers in Immunology, Vol 15 (2025)

Subject Terms: circulating tumor cells, head and neck squamous cell carcinoma (HNSCC), tumor stemness defense (TSD), cancer stem cells (CSCs), tumor hypoxia, platinum chemotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1336882/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/6c7b21ab2914454a93500e8c6bbc5548

Stearoyl CoA desaturase inhibition can effectively induce apoptosis in bladder cancer stem cells

Authors: Yuchen Li, Chiyuan Piao, Chuize Kong

Source: Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)

Subject Terms: Bladder cancer, Stearoyl-CoA desaturase, DNA damage (DDR), Cancer stem cells (CSCs), Apoptosis, ER stress, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/9d23c1b0ae594d0591a3189e6e576037

Nonthermal plasma boosted dichloroacetate induces metabolic shifts to combat glioblastoma CSCs via oxidative stress

Authors: Jaiswal, Apurva ^{a, 1}, Kaushik, Neha ^{b, 1}, Patel, Paritosh ^a, Acharya, Tirtha Raj ^a, Mukherjee, Subhadip ^a, Choi, Eun Ha ^{a, ⁎⁎}, Kaushik, Nagendra Kumar ^{a, ⁎}

Source: In Free Radical Biology and Medicine 1 March 2025 229:264-275

Redox regulation of cancer stem cells: Biology and therapeutic implications

Authors: Min Du, Jian Zhang, Max S. Wicha, Ming Luo

Source: MedComm – Oncology, Vol 3, Iss 4, Pp n/a-n/a (2024)

Subject Terms: cancer stem cells (CSCs), epithelial–mesenchymal plasticity, reactive oxygen species (ROS), redox‐sensitive transcription factors, therapeutic resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2769-6448

Access URL: https://doaj.org/article/967cca8e600a452aa7ef4a9013cbf3e6

Peptide-functionalized gold nanostars-assisted single-cell Raman spectra for molecular analysis of tumor metastasis based on cancer stem cells

Authors: Peng, Zhiyi ^a, Yao, Han ^a, Li, Junqi ^b, Shen, Shuwei ^a, Chen, Guoguang ^{a, ⁎⁎⁎}, Cao, Meng ^{c, ⁎⁎}, Liu, Jia ^{a, ⁎}

Source: In Talanta 1 May 2025 286

Iron metabolism: backfire of cancer cell stemness and therapeutic modalities

Authors: Rong Yu, Yinhui Hang, Hsiang-i Tsai, Dongqing Wang, Haitao Zhu

Source: Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)

Subject Terms: Cancer stem cells (CSCs), Ferroptosis, Iron metabolism, Nanotechnology, Photodynamic diagnosis/Photodynamic therapy, Stemness, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/b7ba04c52cfe4cdd9b336e90ea8b2bd1

ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia

Authors: Tao-Yan Lin, Jun-Shuang Jia, Wei-Ren Luo, Xiao-Lin Lin, Sheng-Jun Xiao, Jie Yang, Jia-Wei Xia, Chen Zhou, Zhi-Hao Zhou, Shu-Jun Lin, Qi-Wen Li, Zhi-Zhi Yang, Ye Lei, Wen-Qing Yang, Hong-Fen Shen, Shi-Hao Huang, Sheng-Chun Wang, Lin-Bei Chen, Yu-Lin Yang, Shu-Wen Xue, Yong-Long Li, Guan-Qi Dai, Ying Zhou, Ying-Chun Li, Fang Wei, Xiao-Xiang Rong, Xiao-Jun Luo, Bing-Xia Zhao, Wen-Hua Huang, Dong Xiao, Yan Sun

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-30 (2024)

Subject Terms: Hyperthermia, Nasopharyngeal carcinoma (NPC), Cold-inducible RNA-binding protein (Cirbp), Temperature-sensitive miRNA-377-3p (termed thermomiR-377-3p), Cancer stem cells (CSCs), Chemotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/4330fc2b5316486db16ac03fb650d0c7

Pen2/ErbB4 signaling regulates stemness of pancreatic ductal carcinoma

Authors: Zhu, Zhongfei ^a, Ding, Dan ^b, Hu, Hao ^{a, ⁎}, He, Tianlin ^{a, ⁎}

Source: In BBA - Molecular Basis of Disease October 2024 1870(7)

Cellular Systems for Colorectal Stem Cancer Cell Research

Authors: Tatyana A. Grigoreva, Daria N. Kindt, Aleksandra V. Sagaidak, Daria S. Novikova, Vyacheslav G. Tribulovich

Source: Cells, Vol 14, Iss 3, p 170 (2025)

Subject Terms: cancer stem cells (CSCs), spheroid, colonosphere, organoid, 3D cell culture, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/3/170; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/ae3348f32e124fd094a42be6f9776f57

iNOS-Produced Nitric Oxide from Cancer Cells as an Intermediate of Stemness Regulation by PARP-1 in Colorectal Cancer

Authors: María del Moral-Martinez, Paula Sánchez-Uceta, Ruben Clemente-Gonzalez, Sara Moreno-SanJuan, Jose D. Puentes-Pardo, Huda Khaldy, David Lopez-Perez, Javier Arnedo, Jorge Casado, Luis Martínez-Heredia, Angel Carazo, Josefa León

Source: Biomolecules, Vol 15, Iss 1, p 125 (2025)

Subject Terms: colorectal cancer (CRC), PARP-1, iNOS, cancer stem cells (CSCs), Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/15/1/125; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/2e778b9d284b42dbb3a541b56730a13c

Natural Killer Cell-Secreted IFN-γ and TNF-α Mediated Differentiation in Lung Stem-like Tumors, Leading to the Susceptibility of the Tumors to Chemotherapeutic Drugs

Authors: Kawaljit Kaur, Angie Perez Celis, Anahid Jewett

Source: Cells, Vol 14, Iss 2, p 90 (2025)

Subject Terms: NK cells, lung cancer, cancer stem cells (CSCs), cytotoxicity, chemo-drugs, IFN-γ, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/2/90; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/a296be5bcb504cda9032be0056964dcb

Hierarchical self-recognition and response in CSC and non-CSC micro-niches for cancer therapy

Authors: Yang, Yiliang ^a, Peng, Yiwei ^a, Du, Yitian ^a, Lin, Meng ^a, Li, Jiajia ^a, Gao, Datong ^a, Yang, Zhenzhen ^{a, b}, Wang, Wei ^c, Zhou, Yanxia ^a, Li, Xinru ^a, Yan, Taiqiang ^{c, ⁎⁎}, Qi, Xianrong ^{a, ⁎}

Source: In Biomaterials July 2024 308

Transcending frontiers in prostate cancer: the role of oncometabolites on epigenetic regulation, CSCs, and tumor microenvironment to identify new therapeutic strategies

Authors: Giulia Ambrosini, Marco Cordani, Ali Zarrabi, Sergio Alcon-Rodriguez, Rosa M. Sainz, Guillermo Velasco, Pedro Gonzalez-Menendez, Ilaria Dando

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)

Subject Terms: Prostate cancer, Oncometabolites, Epigenetic alterations, Cancer stem cells (CSCs), Metabolic Enzymes, EMT, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/f7de861908ba488998eaa45fa750eeaf

Cancer cell cycle heterogeneity as a critical determinant of therapeutic resistance

Authors: Ebrahim H. Maleki, Ahmad Reza Bahrami, Maryam M. Matin

Source: Genes and Diseases, Vol 11, Iss 1, Pp 189-204 (2024)

Subject Terms: Cancer stem cells (CSCs), Carcinoma, Cell cycle heterogeneity, Quiescence, Therapy resistance, Therapy tolerance, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304223000041; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/7af5a0cd7e2943e0b01dfef07236101a

A niche-mimicking polymer hydrogel-based approach to identify molecular targets for tackling human pancreatic cancer stem cells

Authors: Yoshitaka Murota, Mariko Nagane, Mei Wu, Mithun Santra, Seshasailam Venkateswaran, Shinji Tanaka, Mark Bradley, Tetsuya Taga, Kouichi Tabu

Source: Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-11 (2023)

Subject Terms: Cancer stem cells (CSCs), Niche mimicry, Synthetic polymer, Polymer microarray, Hydrogel, Biomaterial, Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/1880-8190

Access URL: https://doaj.org/article/ab5b71a87dc844aabafc19b6d13ea0db

Human Papillomavirus and Head and Neck Cancer

Contributors: Walline, Heather

Subject Terms: head and neck cancer, human papillomavirus, oropharyngeal cancer, virus-related cancers, human papillomavirus diagnosis, sinonasal squamous cell carcinoma, prevalence, detection method, anatomic subsite, photodynamic therapy, ER/mitochondrial photosensitizer, paraptosis, apoptosis, autophagy, HPV, OPSCC, tonsillar cancer, survival, OS, DFS, p16, recurrence, cancer subtypes, gene expression, oropharynx, HPV integration, immune response, keratinization, TATI, Human Papillomavirus (HPV), immune status, hematological parameters, radiotherapy, oropharyngeal squamous cell carcinoma, DNA methylation, transposable elements, overall survival, head and neck squamous cell carcinoma, extracellular vesicle, proteomic, oropharyngeal cancer (OPC), human papillomavirus (HPV), cancer stem cells (CSCs), CSC markers, prognosis, tumor heterogeneity, positron emission tomography, diffusion-weighted, dynamic contrast-enhanced, kinetic modeling, fast exchange regime model, community detection algorithm, spin-glass model, high-risk human papillomaviruses, head and neck squamous cell carcinomas, viral DNA integration, PCR, DIPS-PCR, APOT-PCR, WGS, WES, capture-based assay, RNASeq, FISH, consequences of HPV integration, p53, cancer, glycolysis, oxidative phosphorylation, metabolism, biomarkers, staging, TNM, prognostic, T regulatory lymphocytes, FoxP3, Langerhans cells, CD1a, immune cells, Technology: general issues

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Access URL: https://directory.doabooks.org/handle/20.500.12854/98048
https://mdpi.com/books/pdfview/book/6794