Turning Down the Food Noise.

Authors: YOUNG, LAUREN J. (AUTHOR)

Source: Scientific American. Jul/Aug2024, Vol. 331 Issue 1, p36-41. 6p. 1 Diagram, 1 Cartoon or Caricature.

Subjects: WEIGHT loss, INGESTION, PERIPHERAL nervous system, WEIGHT gain, REWARD (Psychology), GASTROINTESTINAL agents, GASTRIC inhibitory polypeptide, PANCREAS, BLOOD-brain barrier

Hyphal penetration is the major pathway of translocation of Candida albicans across the blood-cerebrospinal fluid barrier.

Authors: Schmidt, S.¹ (AUTHOR), Schwerk, C.² (AUTHOR), Schroten, H.² (AUTHOR), Ishikawa, H.³ (AUTHOR), Schubert, R.⁴ (AUTHOR), Lehrnbecher, T.¹ (AUTHOR), Rudolph, H.¹ (AUTHOR) rudolph@med.uni-frankfurt.de

Source: Fluids & Barriers of the CNS. 4/4/2025, Vol. 22 Issue 1, p1-10. 10p.

Subject Terms: *BLOOD-brain barrier, *TIGHT junctions, *ADHERENS junctions, *CENTRAL nervous system, *CANDIDIASIS

PepH3-modified nanocarriers for delivery of therapeutics across the blood-brain barrier.

Authors: Szecskó, Anikó^1,2 (AUTHOR), Mészáros, Mária^1,3 (AUTHOR), Simões, Beatriz⁴ (AUTHOR), Cavaco, Marco⁴ (AUTHOR), Chaparro, Catarina⁴ (AUTHOR), Porkoláb, Gergő¹ (AUTHOR), Castanho, Miguel A.R.B.⁴ (AUTHOR), Deli, Mária A.¹ (AUTHOR), Neves, Vera⁴ (AUTHOR) veraneves@medicina.ulisboa.pt, Veszelka, Szilvia¹ (AUTHOR) veszelka.szilvia@brc.hu

Source: Fluids & Barriers of the CNS. 4/1/2025, Vol. 22 Issue 1, p1-18. 18p.

Subject Terms: *BLOOD-brain barrier, *PEPTIDES, *GOLGI apparatus, *DRUG delivery systems, *CATIONIC lipids, *ALZHEIMER'S disease

Oxidative Stress: A New Pathophysiological Pathway in Parkinson's Disease and a Potential Target of the Brain‐Sport Crosstalk.

Authors: Caproni, Stefano¹ (AUTHOR), Di Fonzo, Alessio² (AUTHOR), Colosimo, Carlo¹ (AUTHOR) carlo.colosimo@uniroma1.it, Madeo, Graziella (AUTHOR)

Source: Parkinson's Disease (20420080). 3/21/2025, Vol. 2025, p1-10. 10p.

Subject Terms: *MITOCHONDRIA, *BLOOD-brain barrier, *APOPTOSIS, *PARKINSON'S disease, *OXIDATIVE stress, *DOPAMINE, *PHYSICAL activity, *PREVENTIVE health services, *DISEASE risk factors

RBM10 deficiency promotes brain metastasis by modulating sphingolipid metabolism in a BBB model of EGFR mutant lung adenocarcinoma.

Authors: Xu, Gang¹ (AUTHOR), An, Bo¹ (AUTHOR), Wang, Ruqiong¹ (AUTHOR), Pan, Bo¹ (AUTHOR), Hao, Huiting² (AUTHOR), Ren, Xingmei¹ (AUTHOR), Jing, Zihan¹ (AUTHOR), Gao, Weitong¹ (AUTHOR), Li, Yajie¹ (AUTHOR), Jin, Yan³ (AUTHOR), Lin, Enguang⁴ (AUTHOR), Shang, Lihua¹ (AUTHOR) shanglhsmile@163.com, Jia, Dexin¹ (AUTHOR) jiade_xin@126.com, Yu, Yan¹ (AUTHOR) yuyan@hrbmu.edu.cn

Source: Journal of Experimental & Clinical Cancer Research (17569966). 3/11/2025, Vol. 44 Issue 1, p1-20. 20p.

Subject Terms: *EPIDERMAL growth factor receptors, *BLOOD-brain barrier, *BRAIN metastasis, *MOLECULAR biology, *MEDICAL sciences, *RNA-binding proteins

A Single Bout of Physical Exercise Mimicking a Motor Seizure Increases Serum MMP-9, but Not S100B.

Authors: Sielczak, Jan Karol¹ (AUTHOR), Krawczyk, Maciej¹ (AUTHOR), Cudna, Agnieszka¹ (AUTHOR), Kurkowska-Jastrzębska, Iwona¹ (AUTHOR) ikurkowska@ipin.edu.pl

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 5, p1906. 10p.

Subject Terms: *MATRIX metalloproteinases, *BLOOD-brain barrier, *PEOPLE with epilepsy, *SEIZURES (Medicine), *EPILEPSY

Microglial galectin-3 increases with aging in the mouse hippocampus.

Authors: Hyun Joo Shin¹, So Jeong Lee¹, Hyeong Seok An¹, Ha Nyeoung Choi², Eun Ae Jeong¹, Jaewoong Lee¹, Kyung Eun Kim¹, Bong-Hoi Choi³, Seung Pil Yun², Dawon Kang⁴, Sang Soo Kang¹, Gu Seob Roh¹ anaroh@gnu.ac.kr

Source: Korean Journal of Physiology & Pharmacology. Mar2025, Vol. 29 Issue 2, p215-225. 11p.

Subject Terms: *GALECTINS, *BLOOD-brain barrier, *LABORATORY mice, *PHAGOCYTOSIS, *MICROGLIA

Surface-engineered bio-manufactured gas vesicles for multimodal imaging of glioma.

Authors: Li, Juanjuan^1,2 (AUTHOR), Cui, Yutong^2,3 (AUTHOR), Jiang, Xiaoli^1,2 (AUTHOR), Chi, Xue² (AUTHOR), Li, Hong² (AUTHOR), Ma, Xiang² (AUTHOR), Tang, Yanqiong² (AUTHOR), Huang, Denggao⁴ (AUTHOR), Liu, Zhu^1,2 (AUTHOR) zhuliu@ynau.edu.cn

Source: Journal of Nanobiotechnology. 2/18/2025, Vol. 23 Issue 1, p1-14. 14p.

Subject Terms: *BLOOD-brain barrier, *CENTRAL nervous system, *MEDICAL sciences, *ULTRASONIC imaging, *CONTRAST media

Choroid plexus organoids reveal mechanisms of Streptococcus suis translocation at the blood-cerebrospinal fluid barrier.

Authors: Zhao, Tiantong¹ (AUTHOR) tiantongzhao24@gmail.com, Pellegrini, Laura^2,3 (AUTHOR) laura.pellegrini@kcl.ac.uk, van der Hee, Bart¹ (AUTHOR) bart.vanderhee@wur.nl, Boekhorst, Jos¹ (AUTHOR) jos.boekhorst@wur.nl, Fernandes, Aline¹ (AUTHOR), Brugman, Sylvia¹ (AUTHOR) sylvia.brugman@wur.nl, van Baarlen, Peter¹ (AUTHOR) peter.vanbaarlen@wur.nl, Wells, Jerry M.¹ (AUTHOR) jerry.wells@wur.nl

Source: Fluids & Barriers of the CNS. 2/10/2025, Vol. 22 Issue 1, p1-17. 17p.

Subject Terms: *BLOOD-brain barrier, *INDUCED pluripotent stem cells, *TISSUE plasminogen activator, *MEDICAL sciences, *CHOROID plexus

Caloric Restriction Preserves BBB Integrity After Transient Focal Cerebral Ischemia Through Reducing Neutrophil Infiltration.

Authors: Wang, Chenran¹ (AUTHOR), Mao, Leilei¹ (AUTHOR), He, Miao¹ (AUTHOR), Zhang, Jia¹ (AUTHOR), Huang, Yichen¹ (AUTHOR), Zhang, Yue¹ (AUTHOR), Xu, Jing¹ (AUTHOR) shxujing1234@hotmail.com, Huang, Shaoqiang¹ (AUTHOR) drhuangsq@fudan.edu.cn, Gao, Yanqin¹ (AUTHOR) yqgao@shmu.edu.cn

Source: CNS Neuroscience & Therapeutics. Feb2025, Vol. 31 Issue 2, p1-15. 15p.

Subject Terms: *BLOOD-brain barrier, *NEUTROPHILS, *INFLAMMATION, *NEUROPROTECTIVE agents, *TRANSIENT ischemic attack, *STROKE, *LABORATORY mice, *LOW-calorie diet

Advances in the Study of Necroptosis in Vascular Dementia: Focus on Blood–Brain Barrier and Neuroinflammation.

Authors: Qiu, Yuemin^1,2 (AUTHOR), Cheng, Lin^2,3 (AUTHOR), Xiong, Yinyi^2,4 (AUTHOR), Liu, Ziying^1,2 (AUTHOR), Shen, Chunxiao^1,2 (AUTHOR), Wang, Liangliang^1,2 (AUTHOR), Lu, Yujia^1,2 (AUTHOR), Wei, Shufei^1,2 (AUTHOR), Zhang, Lushun^1,2 (AUTHOR), Yang, Seung Bum⁵ (AUTHOR) 123ysb@wu.ac.kr, Zhang, Xiaorong^1,2 (AUTHOR) jjzhangxiaorong@163.com

Source: CNS Neuroscience & Therapeutics. Feb2025, Vol. 31 Issue 2, p1-13. 13p.

Subject Terms: *VASCULAR dementia, *BLOOD-brain barrier, *NEURODEGENERATION, *CELL death, *CEREBRAL ischemia, *CEREBROVASCULAR disease, *NEUROINFLAMMATION, *NECROSIS

Agarwood as a potential therapeutic for Alzheimer's disease: Mechanistic insights and target identification.

Authors: Ya-nan Ma¹, Xiqi Hu¹, Kenji Karako¹, Peipei Song¹, Wei Tang¹, Ying Xia¹

Source: Drug Discoveries & Therapeutics. Dec2024, Vol. 18 Issue 6, p375-386. 12p.

Subject Terms: *ALZHEIMER'S disease, *BLOOD-brain barrier disorders, *NEURODEGENERATION, *PROTEIN-protein interactions, *MEMORY loss, *BLOOD-brain barrier

Exploring the anti-inflammatory effects of curcumin encapsulated within ferritin nanocages: a comprehensive in vivo and in vitro study in Alzheimer's disease.

Authors: Morasso, Carlo¹ (AUTHOR), Truffi, Marta¹ (AUTHOR), Tinelli, Veronica² (AUTHOR), Stivaktakis, Polychronis³ (AUTHOR), Di Gerlando, Rosalinda^4,5 (AUTHOR), Francesca, Dragoni⁵ (AUTHOR), Perini, Giulia⁵ (AUTHOR), Faisal, Mahvish⁶ (AUTHOR), Aid, Jana⁶ (AUTHOR), Noridov, Bekzod⁶ (AUTHOR), Lee, Benjamin⁶ (AUTHOR), Barbieri, Linda² (AUTHOR), Negri, Sara¹ (AUTHOR), Nikitovic, Dragana⁷ (AUTHOR), Thrapsanioti, Lydia-Nefeli⁷ (AUTHOR), Tsatsakis, Aristides³ (AUTHOR), Cereda, Cristina^8,9 (AUTHOR), Bonizzi, Arianna^1,8 (AUTHOR), Mazzucchelli, Serena⁸ (AUTHOR), Prosperi, Davide² (AUTHOR)

Source: Journal of Nanobiotechnology. 11/17/2024, Vol. 22 Issue 1, p1-16. 16p.

Subject Terms: *MONONUCLEAR leukocytes, *BLOOD-brain barrier disorders, *ALZHEIMER'S disease, *TURMERIC, *BLOOD-brain barrier, *INFLAMMATORY mediators, *CURCUMIN

Deciphering the Blood–Brain Barrier Paradox in Brain Metastasis Development and Therapy.

Authors: Peters, Jens Jeshu^1,2,3 (AUTHOR) 228119014@csu.edu.cn, Teng, Chubei^1,2,3 (AUTHOR) tengchubei@csu.edu.cn, Peng, Kang^1,2,3 (AUTHOR) kangpeng01@csu.edu.cn, Li, Xuejun^1,2,3,4 (AUTHOR) lxjneuro@csu.edu.cn

Source: Cancers. Jan2025, Vol. 17 Issue 2, p298. 29p.

Subject Terms: *BRAIN tumor treatment, *BLOOD-brain barrier, *METASTASIS, *BRAIN tumors, *NANOPARTICLES

Anti-inflammatory effects of moxifloxacin and levofloxacin on cadmium-activated human astrocytes: Inhibition of proinflammatory cytokine release, TLR4/STAT3, and ERK/NF-κB signaling pathway.

Authors: Phuagkhaopong, Suttinee¹ (AUTHOR), Sukwattanasombat, Jidapha² (AUTHOR), Suknuntha, Kran³ (AUTHOR), Power, Christopher⁴ (AUTHOR), Wonganan, Piyanuch¹ (AUTHOR), Vivithanaporn, Pornpun³ (AUTHOR) pornpun.viv@mahidol.edu

Source: PLoS ONE. 1/14/2025, Vol. 20 Issue 1, p1-21. 21p.

Subject Terms: *EXTRACELLULAR signal-regulated kinases, *BLOOD-brain barrier, *TOLL-like receptors, *ANTI-inflammatory agents, *INFLAMMATION

A pre-clinical MRI-guided all-in-one focused ultrasound system for murine brain studies.

Authors: Kaovasia, Tarana Parvez¹ (AUTHOR) taranak@umich.edu, Duclos, Sarah¹ (AUTHOR), Gupta, Dinank¹ (AUTHOR), Kalayeh, Kourosh² (AUTHOR), Fabiilli, Mario² (AUTHOR), Noll, Douglas C.^1,2 (AUTHOR), Sukovich, Jonathan¹ (AUTHOR), Pandey, Aditya³ (AUTHOR), Xu, Zhen^1,2,3 (AUTHOR), Hall, Timothy L.¹ (AUTHOR)

Source: Scientific Reports. 1/2/2025, Vol. 15 Issue 1, p1-12. 12p.

Subject Terms: *MAGNETIC resonance imaging, *BLOOD-brain barrier, *ULTRASONIC therapy, *FEVER, *TRANSDUCERS, *HIGH-intensity focused ultrasound

Rnf40 Exacerbates Hypertension‐Induced Cerebrovascular Endothelial Barrier Dysfunction by Ubiquitination and Degradation of Parkin.

Authors: Kou, Chengkun¹ (AUTHOR), Zhao, Xu¹ (AUTHOR), Fan, Xin¹ (AUTHOR), Sun, Runmin¹ (AUTHOR), Wang, Wenting¹ (AUTHOR), Qi, Miaomiao¹ (AUTHOR), Zhu, Lulu¹ (AUTHOR), Lin, Xin¹ (AUTHOR), Yu, Jing^1,2 (AUTHOR) ery_jyu@lzu.edu.cn

Source: CNS Neuroscience & Therapeutics. Jan2025, Vol. 31 Issue 1, p1-15. 15p.

Subject Terms: *HYPERTENSION, *BLOOD-brain barrier, *MITOCHONDRIA, *CEREBROVASCULAR disease, *UBIQUITINATION, *COGNITION disorders, *UBIQUITIN ligases

Penetration of linezolid and tedizolid in cerebrospinal fluid of mouse and impact of blood–brain barrier disruption.

Authors: Lahouati, Marin^1,2 (AUTHOR) marin.lahouati@chu‐bordeaux.fr, Oudart, Mélanie^1,2 (AUTHOR), Alzieu, Philippe² (AUTHOR), Chapouly, Candice² (AUTHOR), Petitcollin, Antoine³ (AUTHOR), Xuereb, Fabien^1,2 (AUTHOR)

Source: CTS: Clinical & Translational Science. Jan2025, Vol. 18 Issue 1, p1-9. 9p.

Subject Terms: *CEREBROSPINAL fluid, *BLOOD-brain barrier, *PHARMACOKINETICS, *ANTI-infective agents, *INFLAMMATION, *ANTIBIOTICS, *LINEZOLID

Reduced oxycodone brain delivery in rats due to lipopolysaccharide-induced inflammation: microdialysis insights into brain disposition and sex-specific pharmacokinetics.

Authors: Bällgren, Frida¹ (AUTHOR), Hammarlund-Udenaes, Margareta¹ (AUTHOR), Loryan, Irena¹ (AUTHOR) irena.loryan@farmaci.uu.se

Source: Fluids & Barriers of the CNS. 12/2/2024, Vol. 21 Issue 1, p1-18. 18p.

Subject Terms: *BLOOD-brain barrier, *MICRODIALYSIS, *MEDICAL sciences, *INTRAVENOUS therapy, *OXYCODONE

Aging Increases Hypoxia-Induced Endothelial Permeability and Blood-Brain Barrier Dysfunction by Upregulating Arginase-II.

Authors: Xin Cheng¹, Potenza, Duilio M.¹, Brenna, Andrea¹, Ajalbert, Guillaume¹, Zhihong Yang¹ zhihong.yang@unifr.ch, Xiu-Fen Ming¹

Source: Aging & Disease. Nov2024, Vol. 15 Issue 6, p2710-2726. 17p.

Subject Terms: *ENDOTHELIAL cells, *BLOOD-brain barrier disorders, *CELL permeability