Integration of metabolomics and chemometrics with in-silico and in-vitro approaches to unravel SARS-Cov-2 inhibitors from South African plants.

Authors: Makoana, Karabo Maselepe¹ (AUTHOR), Naidoo, Clarissa Marcelle¹ (AUTHOR), Zubair, Muhammad Sulaiman² (AUTHOR), Motshudi, Mmei Cheryl¹ (AUTHOR), Mkolo, Nqobile Monate¹ (AUTHOR) nqobile.mkolo@smu.ac.za

Source: PLoS ONE. 3/26/2025, Vol. 20 Issue 3, p1-24. 24p.

Subject Terms: *COVID-19, *ARTEMISIA annua, *SARS-CoV-2, *HYDROGEN bonding, *QUERCETIN

AaMYB121, a Novel R2-MYB-like Transcription Factor, Regulates Artemisinin Biosynthesis in Artemisia annua.

Authors: Li, Dan¹ (AUTHOR) lidans10@126.com, Song, Jiaxin^1,2 (AUTHOR), Tang, Yueli^1,3 (AUTHOR), Zhang, Zeying¹ (AUTHOR) zeyingz@163.com, Yang, Chunxian^1,2 (AUTHOR), Zeng, Lingjiang^1,3 (AUTHOR), Liu, Xiaoqiang¹ (AUTHOR), Chen, Min² (AUTHOR), Lan, Xiaozhong³ (AUTHOR), Zhang, Fangyuan¹ (AUTHOR), Liao, Zhihua¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2441. 16p.

Subject Terms: *TRANSCRIPTION factors, *ARTEMISIA annua, *ARTEMISININ, *BIOSYNTHESIS, *JASMONATE

Exploring the Phytochemical Diversity and Anti-Plasmodial Potential of Artemisia annua and Artemisia afra from Different Geographical Locations in Cameroon.

Authors: Shinyuy, Lahngong M.^1,2,3 (AUTHOR) olivier.bonnet@uliege.be, Loe, Gisèle E.² (AUTHOR), Jansen, Olivia¹ (AUTHOR), Ledoux, Allison¹ (AUTHOR), Palmaerts, Benjamin⁴ (AUTHOR), Mamede, Lúcia¹ (AUTHOR), Boussif, Naima¹ (AUTHOR), Bonnet, Olivier¹ (AUTHOR), Enone, Bertin S.⁵ (AUTHOR), Noukimi, Sandra F.⁶ (AUTHOR), Nchang, Abenwie S.⁷ (AUTHOR), Demeyer, Kristiaan⁵ (AUTHOR), Robert, Annie⁷ (AUTHOR), Ghogomu, Stephen M.³ (AUTHOR), Souopgui, Jacob⁶ (AUTHOR), Hallot, Eric⁴ (AUTHOR), Frederich, Michel¹ (AUTHOR) m.frederich@uliege.be

Source: Molecules. Feb2025, Vol. 30 Issue 3, p596. 18p.

Subject Terms: *HIGH performance liquid chromatography, *ARTEMISIA annua, *REMOTE-sensing images, *GAS chromatography, *ARTEMISININ

Effect of Artemisia annua on anticoccidial action, intestinal microbiota and metabolites of Hu lambs.

Authors: Liu, Shuaiqi^1,2,3 (AUTHOR) 15136117269@163.com, Li, Shiheng^1,2,3 (AUTHOR) 1575615649@qq.com, Cheng, Shuqi^1,2,3 (AUTHOR) c13592559086@163.com, Liu, Manyu^1,2,3 (AUTHOR) 18438615175@163.com, Li, Jing^1,2,3 (AUTHOR) 1632359760@qq.com, Li, Senyang^1,2,3 (AUTHOR) lsylee777@163.com, Li, Xiaoying^1,2,3 (AUTHOR) lixiaoying@henau.edu.cn, Zhang, Longxian^1,2,3 (AUTHOR) zhanglx8999@henau.edu.cn, Jian, Fuchun^1,2,3 (AUTHOR) jfchun2008@163.com

Source: BMC Veterinary Research. 1/30/2025, Vol. 21 Issue 1, p1-17. 17p.

Subject Terms: *GUT microbiome, *ARTEMISIA annua, *WEIGHT gain, *NUCLEOTIDE sequencing, *LAMBS

Exploring the Chemopreventive Potential of Artemisia annua Methanolic Extract in Colorectal Cancer Induced by Azoxymethane in Mice.

Authors: Alrumaihi, Faris¹ (AUTHOR) f_alrumaihi@qu.edu.sa

Source: Pharmaceuticals (14248247). Jan2025, Vol. 18 Issue 1, p34. 18p.

Subject Terms: *COLON cancer, *ARTEMISIA annua, *TUMOR markers, *COLORECTAL cancer, *REACTIVE oxygen species

Dynamic transcriptomics unveils parallel transcriptional regulation in artemisinin and phenylpropanoid biosynthesis pathways under cold stress in Artemisia annua.

Authors: He, Yunxiao¹ (AUTHOR), Zhang, Wenjing¹ (AUTHOR), Zuo, Xianghua¹ (AUTHOR), Li, Jiangnan¹ (AUTHOR), Xing, Ming¹ (AUTHOR), Zhang, Yujiao^1,2 (AUTHOR), You, Jian¹ (AUTHOR) jianyou@jlu.edu.cn, Zhao, Wei¹ (AUTHOR) Cbs1981@163.com, Chen, Xia¹ (AUTHOR) chenxiajlu@163.com

Source: Scientific Reports. 12/28/2024, Vol. 14 Issue 1, p1-13. 13p.

Subject Terms: *METABOLITES, *ARTEMISIA annua, *LIFE sciences, *PHENYLPROPANOIDS, *GENETIC transcription regulation

Unlocking the Therapeutic Benefits of Artemisia Annua: A Comprehensive Overview of its Medicinal Properties.

Authors: Swamikannu, Bhuminathan¹ (AUTHOR), Umapathy, Vidhya Rekha² (AUTHOR) drvidhyarekha@gmail.com, Natarajan, Prabhu M.³ (AUTHOR), Nandini, MS⁴ (AUTHOR), Queency Stylin, Anin G. S.⁵ (AUTHOR), Vimalarani, V⁶ (AUTHOR), Rajinikanth, Suba⁷ (AUTHOR)

Source: Journal of Pharmacy & Bioallied Sciences. 2024 Suppl 5, Vol. 16, pS4248-S4253. 6p.

Subject Terms: *ARTEMISIA annua, *ARTEMISININ derivatives, *ANIMAL experimentation, *MEDICINAL plants, *WORMWOOD

In-silico TOXICITY PREDICTION OF PHENOLIC COMPOUNDS OF Artemisia annua AS ANTICANCER DRUG CANDIDATE.

Authors: Sari, Bina Lohita¹ binalohitasari@unpak.ac.id, Julaeha, Euis², Rahayu, Dien Puji³, Nur Fitriana, Siti Annisa¹

Source: Rasayan Journal of Chemistry. Oct-Dec2024, Vol. 17 Issue 4, p1871-1877. 7p.

Subject Terms: *ARTEMISIA annua, *PHENOLS, *HYDROGEN bonding, *MOLECULAR weights, *THERAPEUTICS

Artemisinin and Its Derivatives as Potential Anticancer Agents.

Authors: Wen, Luan¹ (AUTHOR) 1155209219@link.cuhk.edu.hk, Chan, Ben Chung-Lap¹ (AUTHOR) benchan99@cuhk.edu.hk, Qiu, Ming-Hua² (AUTHOR) mhchiu@mail.kib.ac.cn, Leung, Ping-Chung¹ (AUTHOR) ck-wong@cuhk.edu.hk, Wong, Chun-Kwok^1,3,4 (AUTHOR)

Source: Molecules. Aug2024, Vol. 29 Issue 16, p3886. 20p.

Subject Terms: *ARTEMISININ derivatives, *ARTEMISIA annua, *ANTINEOPLASTIC agents, *HERBAL medicine, *ARTEMISININ

A transcription factor of SHI family AaSHI1 activates artemisinin biosynthesis genes in Artemisia annua.

Authors: Yang, Yinkai¹ (AUTHOR), Li, Yongpeng¹ (AUTHOR), Jin, Li¹ (AUTHOR), Li, Pengyang¹ (AUTHOR), Zhou, Qin¹ (AUTHOR), Sheng, Miaomiao¹ (AUTHOR), Ma, Xiaojing² (AUTHOR), Shoji, Tsubasa³ (AUTHOR), Hao, Xiaolong¹ (AUTHOR) xiaolong19890217@126.com, Kai, Guoyin¹ (AUTHOR) guoyinkai1@126.com

Source: BMC Genomics. 8/9/2024, Vol. 25 Issue 1, p1-15. 15p.

Subject Terms: *TRANSCRIPTION factors, *ARTEMISIA annua, *ARTEMISININ, *GENETIC transcription regulation, *BIOSYNTHESIS

Identification of South African Plant-Based Bioactive Compounds as Potential Inhibitors against the SARS-CoV-2 Receptor.

Authors: Mkolo, Nqobile Monate¹ (AUTHOR) nqobile.mkolo@smu.ac.za, Naidoo, Clarissa Marcelle¹ (AUTHOR) clarissa.naidoo@smu.ac.za, Kadye, Rose² (AUTHOR) rose.kadye@ru.ac.za, Obi, Chikwelu Lawrence¹ (AUTHOR) benson.iweriebor@smu.ac.za, Iweriebor, Benson Chucks¹ (AUTHOR) oyinlola.olaokun@smu.ac.za, Olaokun, Oyinlola Oluwunmi¹ (AUTHOR), Prinsloo, Earl² (AUTHOR) e.prinsloo@ru.ac.za, Zubair, Muhammad Sulaiman³ (AUTHOR) sulaimanzubair@untad.ac.id

Source: Pharmaceuticals (14248247). Jul2024, Vol. 17 Issue 7, p821. 21p.

Subject Terms: *ARTEMISIA annua, *MOLECULAR dynamics, *ANGIOTENSIN converting enzyme, *ORTHOGRAPHIC projection, *PROTEIN receptors

An Update on the Chemical Composition and Pharmacological Profiles of Artemisia species.

Authors: Ansari, Mairaz Varis¹ merajwaris890@gmail.com, Dash, Sribatsa Lanchhana¹, Sahu, Vikram Kumar¹, Dubey, Anubhav¹, Singh Rathor, Virendra Pratap¹

Source: Alinteri Journal of Agriculture Sciences. 2024, Vol. 39 Issue 2, p67-87. 21p.

Subject Terms: *ARTEMISIA, *ANTIMALARIALS, *ESSENTIAL oils, *SPECIES, *TRADITIONAL medicine, *ANTIVIRAL agents, *PLASMODIUM

Geographic Terms: ANTARCTICA

In Vitro and In Silico Anti-Glioblastoma Activity of Hydroalcoholic Extracts of Artemisia annua L. and Artemisia vulgaris L.

Authors: Bernatoniene, Jurga^1,2 (AUTHOR) jurga.bernatoniene@lsmuni.lt, Nemickaite, Emilija¹ (AUTHOR) emilija.nemickaite@stud.lsmu.lt, Majiene, Daiva^1,3 (AUTHOR) daiva.majiene@lsmuni.lt, Marksa, Mindaugas⁴ (AUTHOR) mindaugas.marksa@lsmu.lt, Kopustinskiene, Dalia M.² (AUTHOR) daliamarija.kopustinskiene@lsmuni.lt

Source: Molecules. Jun2024, Vol. 29 Issue 11, p2460. 17p.

Subject Terms: *CHLOROGENIC acid, *ARTEMISIA annua, *BRAIN tumors, *APOPTOSIS, *CELL cycle, *GLIOMAS

Artemisia neosinensis B.H. Jiao and T.G. Gao (Asteraceae), a New Addition to Flora of India from Jammu and Kashmir.

Authors: Liyaqat Ali¹ (AUTHOR) liyaqatali1@yahoo.com, Khuroo, Anzar Ahmad¹ (AUTHOR), Ganie, Aijaz H.² (AUTHOR), Maity, Debabrata³ (AUTHOR)

Source: Biology Bulletin. Jun2024, Vol. 51 Issue 3, p813-816. 4p.

Subject Terms: *BOTANY, *ARTEMISIA, *ASTERACEAE, *PLANT diversity, *SPECIES, *BIOGEOGRAPHY

Geographic Terms: JAMMU & Kashmir (India), HIMALAYA Mountains, INDIA

Exploring the Antibacterial Potential of Artemisia judaica Compounds Targeting the Hydrolase/Antibiotic Protein in Klebsiella pneumoniae : In Vitro and In Silico Investigations.

Authors: Alshammari, Fahdah Ayed¹ (AUTHOR) fahdah.ayed@nbu.edu.sa

Source: Pharmaceuticals (14248247). Jun2024, Vol. 17 Issue 6, p667. 16p.

Subject Terms: *KLEBSIELLA pneumoniae, *ARTEMISIA, *BACTERIAL proteins, *ANTIBIOTICS, *BIOACTIVE compounds, *ETHANOL

The effects of Artemisia annua nutritional supplementation at varying concentrations on broiler growth, economic yield, and gene expression levels of certain antioxidant, inflammatory, and immune genes.

Authors: Mamdouh, Maha¹ maha.mamdouh@fvtm.bu.edu.eg, Shehata, Seham F.² seham.shehata@fvtm.bu.edu.eg, El-Keredy, Amira³ amira.el-keredy@agr.tanta.edu.eg, Awad, Dina A.⁴ dina.awad@fvtm.bu.edu.eg, El-Rayes, Talaat Khedr⁵ talat.elrais@agr.tanta.edu.eg, Elsokary, Mohamed M. M.^6,7 mohamed.alsokary@fvtm.bu.edu.eg, Baloza, Samar H.⁸ samar.blouza@fvtm.bu.edu.eg

Source: Veterinary World. Jun2024, Vol. 17 Issue 6, p1318-1327. 10p.

Subject Terms: *ARTEMISIA annua, *POULTRY growth, *CHICKS, *GENE expression, *TUMOR necrosis factors, *POULTRY farming, *GLUTATHIONE peroxidase

Synergistic antifungal activity of combinations of Artemisia annua extract with fluconazole against resistant strains of Candida albicans.

Authors: Ngwu, Maria I.¹, Ngwu, Godwin I.² godwin.ngwu@unn.edu.ng, Okorie, Chibundo N.¹, Emencheta, Stephen C.¹, Odimegwu, Damian C.¹, Attama, Anthony A.³, Ibezim, Emmanuel C.³

Source: Tropical Journal of Pharmaceutical Research. Jun2024, Vol. 23 Issue 6, p941-949. 9p.

Subject Terms: *ANTIFUNGAL agents, *ARTEMISIA annua, *CANDIDA albicans, *FLUCONAZOLE, *HEALTH facilities, *TEACHING hospitals

Geographic Terms: ENUGU (Nigeria)

Phytoconstituents of Artemisia Annua as potential inhibitors of SARS CoV2 main protease: an in silico study.

Authors: Irfan, Eraj¹ (AUTHOR), Dilshad, Erum¹ (AUTHOR) dr.erum@cust.edu.pk, Ahmad, Faisal² (AUTHOR), Almajhdi, Fahad Nasser³ (AUTHOR), Hussain, Tajamul⁴ (AUTHOR), Abdi, Gholamreza⁵ (AUTHOR) abdi@pgu.ac.ir, Waheed, Yasir^6,7,8 (AUTHOR) yasir_waheed_199@hotmail.com

Source: BMC Infectious Diseases. 5/15/2024, Vol. 24 Issue 1, p1-19. 19p.

Subject Terms: *ARTEMISIA annua, *VIRUS-induced enzymes, *QUINIC acid, *CAFFEIC acid, *AZITHROMYCIN

Molecular characterization of methanol extract of Artemisia annua leaf and its antifungal activity on clinical isolates of Candida albicans.

Authors: Ngwu, Maria I.¹, Emencheta, Stephen C.¹ stephen.emencheta@unn.edu.ng, Agbo, Chinazom P.², Ngwu, Godwin I.³, Agbo, Martina C.¹, Okorie, Chibundo N.¹, Odimegwu, Damian C.¹, Eze, Frankline C.¹, Attama, Anthony A.², Ibezim, Emmanuel C.²

Source: Tropical Journal of Pharmaceutical Research. May2024, Vol. 23 Issue 5, p855-861. 7p.

Subject Terms: *ARTEMISIA annua, *CANDIDA albicans, *ANTIFUNGAL agents, *TEACHING hospitals, *DNA primers, *POLYMERASE chain reaction, *MEDICAL laboratories

Geographic Terms: NIGERIA

Resistance of Microbial Community of Artemisia annua L. to Pathogenic Fungi.

Authors: Zerong GENG¹, Tianhua YU¹, Zhannan YANG¹ yangzhannan@163.com, Shiqiong LUO² shiqiongluo@163.com

Source: Plant Diseases & Pests. Feb2024, Vol. 15 Issue 1, p7-15. 9p.

Subject Terms: Pathogenic fungi, Artemisia annua, Microbial communities, Phytopathogenic fungi, Fungal communities, Bacterial communities, Plant-fungus relationships