Therapeutic efficacy of artemether–lumefantrine in North-Eastern states of India and prevalence of drug resistance-associated molecular markers

Authors: Shreelekha Dutta, Sri Krishna, Anup Kumar Vishwakarma, Sweta Mishra, Sushrikanta Khandai, Disphikha Goswami, Soni Kumari, Nazia Ali, Anil Kumar Verma, Kuldeep Singh, Aparup Das, Anup R. Anvikar, Praveen Kumar Bharti

Source: Malaria Journal, Vol 24, Iss 1, Pp 1-12 (2025)

Subject Terms: Therapeutic efficacy, Artemether–lumefantrine, Antimalarial drug resistance, Molecular monitoring, North-East India, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/5feb579df5f941a8b4e3589808c766ce

Increasing day three parasitaemia is observed after treatment of patients with artemether-lumefantrine and single dose of primaquine for uncomplicated Plasmodium falciparum malaria in Arbaminch Zuria district, Southwest Ethiopia

Authors: Bontu Abate, Bokretsion Gidey Brhane, Tsegahun Manyazewal, Hussien Mohammed, Yonas Wuletaw, Moges Kassa, Mesay Hailu, Getachew Tollera, Geremew Tasew, Ashenafi Assefa, Eyasu Makonnen

Source: Malaria Journal, Vol 24, Iss 1, Pp 1-12 (2025)

Subject Terms: Efficacy, Safety, Artemether-lumefantrine, Plasmodium-falciparum, Ethiopia, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/e893aef482224af98611a73da850f22a

Solidified reverse micellar solution-based chitosan-coated solid lipid nanoparticles as a new approach to enhance oral delivery of artemether in malaria treatment

Authors: Franklin Chimaobi Kenechukwu, Kingsley Chinazam Ugwu, Chibuzor Stanley Offorbuike, Enyi Moses Ojukwu, Thaddeus Harrison Gugu, Reuben Ejike Eze, Chinazom Precious Agbo, Mumuni Audu Momoh, Anthony Ikechukwu Onah, Chinekwu Sherridan Nwagwu, Onyinyechi Lydia Ugorji, Emmanuel Chekwube Ossai, Calister Elochukwu Ugwu, Paul Achile Akpa, Adaeze Chidiebere Echezona, Samuel WisdomofGod Uzondu, Chimaobi Odinaka Ugorji, Wilfred Ikechukwu Ugwuoke, Teerapol Srichana, Anthony Amaechi Attama

Source: BMC Chemistry, Vol 19, Iss 1, Pp 1-25 (2025)

Subject Terms: Solidified reverse micellar solution, Antimalarial activity, Chitosan, Solid lipid nanoparticles, Artemether, Plasmodium berghei, Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2661-801X

Access URL: https://doaj.org/article/2aec4bbfd65b4e48be2f466c7cde75f0

Effects of nanocapsules containing lumefantrine and artemether in an experimental model of cerebral malaria

Authors: Bianca Portugal Tavares de Moraes, Karoline Paiva da Silva, Karina Paese, Adilson Paulo Sinhorin, Silvia S. Guterres, Adriana R. Pohlmann, Isabelle Moraes-de-Souza, Sarah de Oliveira Rodrigues, Kauê Francisco Corrêa e SouzaSouza, Carolina Medina Coeli da Cunha, Matheus Augusto Patrício de Almeida, Patrícia Torres Bozza, Hugo Caire de Castro-Faria-Neto, Adriana Ribeiro Silva, Cassiano Felippe Gonçalves-de-Albuquerque, Stela Regina Ferrarini

Source: Discover Nano, Vol 19, Iss 1, Pp 1-14 (2024)

Subject Terms: Lipid core nanocapsules, Cerebral malaria, Lumefantrine, Artemether, Microcirculation, Materials of engineering and construction. Mechanics of materials, TA401-492

File Description: electronic resource

Relation: https://doaj.org/toc/2731-9229

Access URL: https://doaj.org/article/5c7f21adc90544aea97ee65e9bd68bf5

Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics

Authors: Tao Jiang, Peipei Du, Dongxia Liu, Hetao Chen, Yujin Ma, Bin Hu, Jingna Li, Hongwei Jiang, Xuejiao Li

Source: Frontiers in Pharmacology, Vol 16 (2025)

Subject Terms: T2DM, network pharmacology, artemether, metabolomics, gut microbiota, AMPK/mTOR pathway, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2025.1520439/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/0d26fa43ddc748159d1b08cab141e140

Therapeutic efficacy and safety of artemether-lumefantrine combination therapy for the treatment of uncomplicated Plasmodium falciparum malaria at Teda Health Centre, Northwest Ethiopia, 2022/23

Authors: Dagmawi Woldesenbet, Meseret Birhanie, Aberham Abere, Ayalew Jejaw Zeleke, Migbaru Keffale Bezabih, Muluken Semaw, Menberu Wubetie, Wagaw Abebe, Elias Tamene, Yalewayker Tegegne

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-13 (2024)

Subject Terms: Efficacy, Plasmodium falciparum, Malaria, Artemether-lumefantrine, Teda, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/dfe7031cbb6d474cb3a9f71156f7962e

Assessing the therapeutic efficacy of artemether-lumefantrine for uncomplicated malaria in Lagos, Nigeria: a comprehensive study on treatment response and resistance markers

Authors: Kolapo M. Oyebola, Funmilayo C. Ligali, Afolabi J. Owoloye, Oluwagbemiga O. Aina, Yetunde M. Alo, Blessing Erinwusi, Michael J. Olufemi, Babatunde L. Salako

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-11 (2024)

Subject Terms: Artemether-lumefantrine, Genetic diversity, Nigeria, mdr1, ubp1, ACPR, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/a3b7a6b09d1d401fa9dca822ba9e5481

Artemether relieves liver fibrosis by triggering ferroptosis in hepatic stellate cells via DHHC12-mediated S-palmitoylation of the BECN1 protein

Authors: Li, Mengran ^a, Sun, Yuqi ^a, Wei, Yuyao ^a, Li, Yujia ^b, Shao, Jiang Juan ^a, Guo, Mei ^a, Zheng, Shizhong ^{a, ⁎}, Zhang, Zili ^{a, ⁎⁎}

Source: In Free Radical Biology and Medicine April 2025 231:120-135

Vitamin C co-administration with artemether-lumefantrine abrogates chronic stress exacerbated Plasmodium berghei-induced sickness behaviour, inflammatory and oxidative stress responses in mice

Authors: Ogundeyi, Kehinde Joshua ^a, Ajayi, Abayomi Mayowa ^{a, ⁎}, Oduyomi, Ololade Justina ^a, Adeyemo, Stella Afolakemi ^a, Ologe, Mary O. ^b, Ademowo, Olusegun George ^{a, c}

Source: In Journal of Neuroimmunology 15 February 2025 399

Incompatibility of antimalarial drugs: challenges in formulating combination products for malaria

Authors: Ellen K. G. Mhango, Benjamin R. Sveinbjornsson, Bergthora S. Snorradottir, Sveinbjorn Gizurarson

Source: Drug Delivery, Vol 31, Iss 1 (2024)

Subject Terms: Artemether, lumefantrine, solubility, incompatibility, malaria, fatty acids, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/3b307c47f4b3455a935044d90458b6aa

Artemether exerts neuroprotective effect in Parkinson's disease through the PI3K/Akt/GSK-3β signaling pathway

Authors: Quan, Shengli ^{a, b, 1}, Li, Jinhua ^{a, b, 1}, Ding, Shuxian ^{a, b}, Zhuo, Xingjie ^{a, b}, Yang, Yuanxiao ^{a, b}, Li, Qin ^{a, b, ⁎}

Source: In European Journal of Pharmacology 5 June 2025 996

Therapeutic efficacy and safety of artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria treatment in Metehara, Central-east Ethiopia

Authors: Mahelet Tesfaye, Ashenafi Assefa, Henok Hailgiorgis, Bokretsion Gidey, Hussein Mohammed, Getachew Tollera, Geremew Tasew, Gudissa Assefa, Worku Bekele, Hassen Mamo

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-11 (2024)

Subject Terms: Plasmodium falciparum, Therapeutic efficacy, Artemether-lumefantrine, Metehara, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/42eab06b225e4d0291ca96f31d31bc2b

Preparation and characterization of artemether-loaded niosomes in Leishmania major-induced cutaneous leishmaniasis

Authors: Uranous Niroumand, Mohammad Hossein Motazedian, Fatemeh Ahmadi, Qasem Asgari, Mohammad Saleh Bahreini, Parisa Ghasemiyeh, Soliman Mohammadi-Samani

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Subject Terms: Artemether, Niosomes, Topical drug delivery, Cutaneous leishmaniasis, Leishmania major, Promastigote, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0e76083a83c149c2a5ef1fe3ec44f706

Therapeutic efficacy and tolerability of artemether–lumefantrine for uncomplicated Plasmodium falciparum malaria in Niger, 2020

Authors: Ibrahim M. Laminou, Ibrahima Issa, Eric Adehossi, Kabirou Maman, Hadiza Jackou, Eric Coulibaly, Zilahatou B. Tohon, Jehan Ahmed, Elisha Sanoussi, Daniel Koko

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-10 (2024)

Subject Terms: Resistance, P. falciparum, Artemether–lumefantrine, Efficacy, Niger, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/dbc7018bd6344890b8889052d75cc750

Polymeric Nanoparticles for Biomedical Applications

Contributors: Andrade, Stephanie, Loureiro, Joana A., Ramalho, Maria João

Subject Terms: Angiopep-2, nanoparticles, transcytosis, drug delivery, brain, targeting, chemotherapy, cancer, polysaccharides, toxicity, nanomaterials, polymers, drug release, local delivery, administration routes, thermosensitive hydrogel, cancer therapy, chronic wound treatment, sunitinib, lipoid 90H, chitosan, breast cancer, caspase, enhanced permeability and retention effect, nanotechnology, tumor microenvironment, Zwitterionic polymers, synthetic microbe, macrophages, liposomes, glioblastoma multiforme, hybrid nanoparticle, apigenin, sustained release, mTOR, apoptosis, colon cancer, biomedical application, imaging, photo-thermal therapy, sensors, nanocapsules, QT interval, cardiotoxicity, artemether, malaria, self-assembled polymers, polylactide, lysozyme, carboxymethyl starch, layer-by-layer self assembly, enteric infection, nanofiber, scaffold, electrospinning, tissue engineering, regenerative medicine, cervical cancer, copper oxide, green synthesis, cytotoxicity, gene delivery, folate targeting, natural polymers, synthetic polymers, copolymers, biomimetic, biomedical applications, dextran, fractal features, hydroxyapatite, magnesium, Technology: general issues

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/137522
https://mdpi.com/books/pdfview/book/8682

Efficacy of artemether-lumefantrine and dihydroartemisinin-piperaquine and prevalence of molecular markers of anti-malarial drug resistance in children in Togo in 2021

Authors: Ameyo Monique Dorkenoo, Marian Warsame, Essoham Ataba, Manani Hemou, Kossi Yakpa, Efoe Sossou, M’badi Mitigmsagou, Carmel Diwaba Teou, Emmanuelle Caspar, Laurence Ma, Koffi Edem Djadou, Tinah Atcha-Oubou, Charlotte Rasmussen, Didier Menard

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-17 (2024)

Subject Terms: Artemether-lumefantrine, Dihydroartemisinin-piperaquine, Plasmodium falciparum, Efficacy, Molecular markers of antimalarial drug resistance, Togo, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/84a2192568d44c24b6bbd91ca6b741bc

Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in mainland Tanzania, 2018

Authors: Billy Ngasala, Mercy G. Chiduo, Samwel Bushukatale, Bruno P. Mmbando, Twilumba Makene, Erasmus Kamugisha, Maimuna Ahmed, Celine I. Mandara, Filbert Francis, Muhidin K. Mahende, Reginald A. Kavishe, Florida Muro, Deus S. Ishengoma, Renata Mandike, Fabrizio Molteni, Frank Chacky, Chonge Kitojo, George Greer, Dunstan Bishanga, Jasmine Chadewa, Ritha Njau, Marian Warsame, Bilali Kabula, Ssanyu S. Nyinondi, Erik Reaves, Ally Mohamed

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-10 (2024)

Subject Terms: Malaria, Plasmodium falciparum, Artemether lumefantrine, Therapeutic efficacy, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/362a297cf2994c71b915f580c1f2fc9c

Therapeutic efficacy of generic artemether–lumefantrine in the treatment of uncomplicated malaria in Ghana: assessing anti-malarial efficacy amidst pharmacogenetic variations

Authors: Nicholas Ekow Thomford, Tracy Kellermann, Robert Peter Biney, Charné Dixon, Samuel Badu Nyarko, Richmond Owusu Ateko, Martins Ekor, George B. Kyei

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-14 (2024)

Subject Terms: Pharmacogenomics, Pharmacokinetics, Generic anti-malarials, Artemether–lumefantrine, CYP2B6, CYP3A5, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/56d44acc96d0423eabea7612c282d724

Implementation of post-discharge malaria chemoprevention (PDMC) in Benin, Kenya, Malawi, and Uganda: stakeholder engagement meeting report

Authors: Jenny Hill, PDMC Saves Lives Consortium

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)

Subject Terms: Post-discharge malaria chemoprevention (PDMC), Dihydroartemisinin-piperaquine (DP), Artemether-lumefantrine (AL), Sulfadoxine-pyrimethamine (SP), Sulfadoxine-pyrimethamine and amodiaquine (SP-AQ), Artesunate-amodiaquine (AS-AQ), Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/52fdd7cb1b8b4945b6930f29aafe9e75

Effectiveness of artemether–lumefantrine for treating uncomplicated malaria in low- and high-transmission areas of Ghana

Authors: Mawusi Adepa Mawuli, Linda Eva Amoah, Liwang Cui, Neils Ben Quashie, Yaw Asare Afrane

Source: Malaria Journal, Vol 23, Iss 1, Pp 1-8 (2024)

Subject Terms: Artemether–lumefantrine, Delayed parasite clearance Ghana, Plasmodium falciparum, Uncomplicated malaria, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/498634f0641a4e2fbaad9fbe78191055