Anti-TNFα and Anti-IL-1β Monoclonal Antibodies Preserve BV-2 Microglial Homeostasis Under Hypoxia by Mitigating Inflammatory Reactivity and ATF4/MAPK-Mediated Apoptosis

Authors: Linglin Zhang, Chaoqiang Guan, Sudena Wang, Norbert Pfeiffer, Franz H. Grus

Source: Antioxidants, Vol 14, Iss 3, p 363 (2025)

Subject Terms: microglia, hypoxia, mitochondria, inflammatory pathways, anti-TNFα, anti-IL-1β, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/14/3/363; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/4c57e78899ba48f6811217224e90d4f8

NLRP3 inflammasome and NLRP3-related autoinflammatory diseases: From cryopyrin function to targeted therapies

Authors: Chiara Moltrasio, Maurizio Romagnuolo, Angelo Valerio Marzano

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: inflammasome, NLRP3, cryopyrin associated periodic syndrome, gain-of-functions, mutations, anti-IL-1β treatments, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1007705/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/129fa20220354b8da79fdd87f55285cc