DAGIP: alleviating cell-free DNA sequencing biases with optimal transport

Authors: Antoine Passemiers, Stefania Tuveri, Tatjana Jatsenko, Adriaan Vanderstichele, Pieter Busschaert, An Coosemans, Dirk Timmerman, Sabine Tejpar, Peter Vandenberghe, Diether Lambrechts, Daniele Raimondi, Joris Robert Vermeesch, Yves Moreau

Source: Genome Biology, Vol 26, Iss 1, Pp 1-30 (2025)

Subject Terms: Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/1a12975614c84f1ea803e7299cbf9990

Tumor Treating Fields (TTFields) induce homologous recombination deficiency in ovarian cancer cells, thus mitigating drug resistance

Authors: Yani Berckmans, Hila M. Ene, Kerem Ben-Meir, Antonia Martinez-Conde, Roxanne Wouters, Bieke Van den Ende, Sara Van Mechelen, Roni Monin, Roni Frechtel-Gerzi, Hila Gabay, Eyal Dor-On, Adi Haber, Uri Weinberg, Ignace Vergote, Moshe Giladi, An Coosemans, Yoram Palti

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: Tumor Treating Fields (TTFields), ovarian cancer, drug resistance, DNA damage, synthetic lethality, conditional vulnerability, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1402851/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/3e0b6e18f9dc4e9395f4d2768ea4274b

Editorial: Challenges associated with identifying preclinical animal models for the development of immune-based therapies

Authors: Kainat Jamil, Shardulendra P. Sherchand, Rajan P. Adhikari, An Coosemans

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: animal, preclinical (in vivo) studies, immunotherapy, immune-based therapeutics, editorial, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1404085/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/45fcc97bad304b769f59d36ac109227c

Trial watch: chemotherapy-induced immunogenic cell death in oncology

Authors: Jenny Sprooten, Raquel S. Laureano, Isaure Vanmeerbeek, Jannes Govaerts, Stefan Naulaerts, Daniel M. Borras, Lisa Kinget, Jitka Fucíková, Radek Špíšek, Lenka Palová Jelínková, Oliver Kepp, Guido Kroemer, Dmitri V. Krysko, An Coosemans, Rianne D.W. Vaes, Dirk De Ruysscher, Steven De Vleeschouwer, Els Wauters, Evelien Smits, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, Hans Wildiers, Paul M. Clement, Peter Vandenabeele, Laurence Zitvogel, Abhishek D. Garg

Source: OncoImmunology, Vol 12, Iss 1 (2023)

Subject Terms: CAR T cells, antigen-presenting cells, chemotherapy, danger signals, dendritic cell, immune-checkpoint blockers, immunogenic cell death, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/7008e019d7c247f4ac120beabac8edc7

Preclinical studies performed in appropriate models could help identify optimal timing of combined chemotherapy and immunotherapy

Authors: Yani Berckmans, Jolien Ceusters, Ann Vankerckhoven, Roxanne Wouters, Matteo Riva, An Coosemans

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: immune checkpoint inhibitors, chemotherapy, preclinical models, combination treatment, cancer therapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1236965/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/04cf28e71bf847afb875ab0b088ad270

MHyNet-PC: A Multi-Modal Hybrid No-Reference Framework for Point Cloud Quality Assessment

Authors: Chatterjee, Jit, Creemers, Michiel, Coosemans, Jens, Vega, Maria Torres

Source: 2024 IEEE Thirteenth International Conference on Image Processing Theory, Tools and Applications (IPTA) Image Processing Theory, Tools and Applications (IPTA), 2024 IEEE Thirteenth International Conference on. :01-06 Oct, 2024

Relation: 2024 IEEE Thirteenth International Conference on Image Processing Theory, Tools and Applications (IPTA)

Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer

Authors: Adriaan Vanderstichele, Pieter Busschaert, Chiara Landolfo, Siel Olbrecht, An Coosemans, Wouter Froyman, Liselore Loverix, Nicole Concin, Elena Ioana Braicu, Pauline Wimberger, Els Van Nieuwenhuysen, Sileny N. Han, Toon Van Gorp, Tom Venken, Ruben Heremans, Patrick Neven, Tom Bourne, Ben Van Calster, Dirk Timmerman, Diether Lambrechts, Ignace Vergote

Source: npj Genomic Medicine, Vol 7, Iss 1, Pp 1-9 (2022)

Subject Terms: Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2056-7944

Access URL: https://doaj.org/article/6571537f895e4d2b8a539a4af5fd1176

A Microfluidics Approach for Ovarian Cancer Immune Monitoring in an Outpatient Setting

Authors: Sarah Libbrecht, Ann Vankerckhoven, Koen de Wijs, Thaïs Baert, Gitte Thirion, Katja Vandenbrande, Toon Van Gorp, Dirk Timmerman, An Coosemans, Liesbet Lagae

Source: Cells, Vol 13, Iss 1, p 7 (2023)

Subject Terms: flow cytometry, lab on chip, immune monitoring, ovarian cancer, immunotherapy, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/1/7; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/2e9bc2a2e7a64637a5d30c33cf2b18b4

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Authors: Khalid El Bairi, Harry R. Haynes, Elizabeth Blackley, Susan Fineberg, Jeffrey Shear, Sophia Turner, Juliana Ribeiro de Freitas, Daniel Sur, Luis Claudio Amendola, Masoumeh Gharib, Amine Kallala, Indu Arun, Farid Azmoudeh-Ardalan, Luciana Fujimoto, Luz F. Sua, Shi-Wei Liu, Huang-Chun Lien, Pawan Kirtani, Marcelo Balancin, Hicham El Attar, Prerna Guleria, Wenxian Yang, Emad Shash, I-Chun Chen, Veronica Bautista, Jose Fernando Do Prado Moura, Bernardo L. Rapoport, Carlos Castaneda, Eunice Spengler, Gabriela Acosta-Haab, Isabel Frahm, Joselyn Sanchez, Miluska Castillo, Najat Bouchmaa, Reena R. Md Zin, Ruohong Shui, Timothy Onyuma, Wentao Yang, Zaheed Husain, Karen Willard-Gallo, An Coosemans, Edith A. Perez, Elena Provenzano, Paula Gonzalez Ericsson, Eduardo Richardet, Ravi Mehrotra, Sandra Sarancone, Anna Ehinger, David L. Rimm, John M. S. Bartlett, Giuseppe Viale, Carsten Denkert, Akira I. Hida, Christos Sotiriou, Sibylle Loibl, Stephen M. Hewitt, Sunil Badve, William Fraser Symmans, Rim S. Kim, Giancarlo Pruneri, Shom Goel, Prudence A. Francis, Gloria Inurrigarro, Rin Yamaguchi, Hernan Garcia-Rivello, Hugo Horlings, Said Afqir, Roberto Salgado, Sylvia Adams, Marleen Kok, Maria Vittoria Dieci, Stefan Michiels, Sandra Demaria, Sherene Loi, The International Immuno-Oncology Biomarker Working Group

Source: npj Breast Cancer, Vol 7, Iss 1, Pp 1-17 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2374-4677

Access URL: https://doaj.org/article/98d18f7227c34bcb8909cccb39302c30

Peripheral gene signatures reveal distinct cancer patient immunotypes with therapeutic implications for autologous DC-based vaccines

Authors: Michal Hensler, Jana Rakova, Lenka Kasikova, Tereza Lanickova, Josef Pasulka, Peter Holicek, Marek Hraska, Tereza Hrnciarova, Pavla Kadlecova, Andreu Schoenenberger, Klara Sochorova, Daniela Rozkova, Ludek Sojka, Jana Drozenova, Jan Laco, Rudolf Horvath, Michal Podrazil, Guo Hongyan, Tomas Brtnicky, Michal J. Halaska, Lukas Rob, Ales Ryska, An Coosemans, Ignace Vergote, Abhishek D. Garg, David Cibula, Jirina Bartunkova, Radek Spisek, Jitka Fucikova

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: Cancer immunotherapy, metastatic castrate-resistant prostate cancer, non-small cell lung carcinoma, epithelial ovarian carcinoma, circulating biomarkers, anti-PD-1, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/8aa6cc35d16f49fbb0529e5fcefe2e0f

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

Authors: Raquel S Laureano, Jenny Sprooten, Isaure Vanmeerbeerk, Daniel M Borras, Jannes Govaerts, Stefan Naulaerts, Zwi N Berneman, Benoit Beuselinck, Kalijn F Bol, Jannie Borst, an Coosemans, Angeliki Datsi, Jitka Fučíková, Lisa Kinget, Bart Neyns, Gerty Schreibelt, Evelien Smits, Rüdiger V Sorg, Radek Spisek, Kris Thielemans, Sandra Tuyaerts, Steven De Vleeschouwer, I Jolanda M de Vries, Yanling Xiao, Abhishek D Garg

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: Dendritic cells, DAMPs, TAAs, antigen cross-presentation, T cell priming, immune checkpoint blockers, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/be78d83094d145fe958410723c8c8404

A first-in-class, non-invasive, immunodynamic biomarker approach for precision immuno-oncology

Authors: Jenny Sprooten, An Coosemans, Abhishek D. Garg

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: immunosurveillance, anticancer immunity, inhibitory receptors, lymphocytes, benign or borderline lesions, immunology, neutrophils, wound healing, tgfb1, pattern-recognition receptors (prrs), ovarian canc er, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/73f0cdc9ceb144bcbbfc7fc1c640c633

Intraperitoneal alpha therapy with 224Ra-labeled microparticles combined with chemotherapy in an ovarian cancer mouse model

Authors: Roxanne Wouters, Sara Westrøm, Yani Berckmans, Matteo Riva, Jolien Ceusters, Tina B. Bønsdorff, Ignace Vergote, An Coosemans

Source: Frontiers in Medicine, Vol 9 (2022)

Subject Terms: ovarian cancer, alpha therapy, radium-224, chemotherapy, carboplatin, paclitaxel, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2022.995325/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/293bce168e4649ebab737b967704a0ad

High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification

Authors: Siel Olbrecht, Pieter Busschaert, Junbin Qian, Adriaan Vanderstichele, Liselore Loverix, Toon Van Gorp, Els Van Nieuwenhuysen, Sileny Han, Annick Van den Broeck, An Coosemans, Anne-Sophie Van Rompuy, Diether Lambrechts, Ignace Vergote

Source: Genome Medicine, Vol 13, Iss 1, Pp 1-30 (2021)

Subject Terms: Single-cell RNA sequencing, High-grade serous tubo-ovarian cancer, Molecular subtypes, Stromal heterogeneity, Transcriptomic markers, Tumour microenvironment, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/459116037da349fdb4ec4aa3a3f0dd65

Simultaneous in vivo PET/MRI using fluorine-18 labeled Fe3O4@Al(OH)3 nanoparticles: comparison of nanoparticle and nanoparticle-labeled stem cell distribution

Authors: Sarah Belderbos, Manuel Antonio González-Gómez, Frederik Cleeren, Jens Wouters, Yolanda Piñeiro, Christophe M. Deroose, An Coosemans, Willy Gsell, Guy Bormans, Jose Rivas, Uwe Himmelreich

Source: EJNMMI Research, Vol 10, Iss 1, Pp 1-13 (2020)

Subject Terms: Cell tracking, Nanoparticles, Preclinical imaging, Radiolabeling, PET/MRI, Stem cells, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13550-020-00655-9; https://doaj.org/toc/2191-219X

Access URL: https://doaj.org/article/a14586c50601480f987bbe0dfea69fb8

Drug Repurposing for Targeting Myeloid-Derived Suppressor-Cell-Generated Immunosuppression in Ovarian Cancer: A Literature Review of Potential Candidates

Authors: Yani Berckmans, Yannick Hoffert, Ann Vankerckhoven, Erwin Dreesen, An Coosemans

Source: Pharmaceutics, Vol 15, Iss 7, p 1792 (2023)

Subject Terms: ovarian cancer, drug repurposing, myeloid-derived suppressor cells, treatment strategies, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/7/1792; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/8ac883b1478c44038a21c7cfea8fddf9

Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer

Authors: Antonia Carla Testa, Sabine Tejpar, Ignace Vergote, Valentina Chiappa, An Coosemans, Thaïs Baert, Chiara Landolfo, Wouter Froyman, Dirk Timmerman, Tom Bourne, Abhishek D Garg, Patrizia Agostinis, Louis Boon, Daniela Fischerova, Caroline Van Holsbeke, Jenny Sprooten, Ann Vankerckhoven, Isaure Vanmeerbeek, Daniel M Borras, Yani Berckmans, Roxanne Wouters, Raquel S Laureano, Dominique Schols

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/11/e003609.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/c7317b3b6a0e4a03af4f9f35a3b5424c

Real-world validation of safe reinforcement learning, model predictive control and decision tree-based home energy management systems

Authors: Ruddick, Julian, Ceusters, Glenn, Van Kriekinge, Gilles, Genov, Evgenii, De Cauwer, Cedric, Coosemans, Thierry, Messagie, Maarten

Subject Terms: Electrical Engineering and Systems Science - Systems and Control, Computer Science - Artificial Intelligence, Computer Science - Machine Learning, Computer Science - Neural and Evolutionary Computing

Access URL: http://arxiv.org/abs/2408.07435

Type of chemotherapy has substantial effects on the immune system in ovarian cancer

Authors: Ann Vankerckhoven, Thaïs Baert, Matteo Riva, Christine De Bruyn, Gitte Thirion, Katja Vandenbrande, Jolien Ceusters, Ignace Vergote, An Coosemans

Source: Translational Oncology, Vol 14, Iss 6, Pp 101076- (2021)

Subject Terms: Ovarian cancer, Chemotherapy, MDSC, Carboplatin-paclitaxel, Immunosuppression, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523321000681; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/0ec0490761374d4cacf0cee7395fe6b6

CryptoCEST: A promising tool for spatially resolved identification of fungal brain lesions and their differentiation from brain tumors with MRI

Authors: Liesbeth Vanherp, Kristof Govaerts, Matteo Riva, Jennifer Poelmans, An Coosemans, Katrien Lagrou, Willy Gsell, Greetje Vande Velde, Uwe Himmelreich

Source: NeuroImage: Clinical, Vol 31, Iss , Pp 102737- (2021)

Subject Terms: CEST MR imaging, MR spectroscopy, Fungal infection, Cryptococcosis, Trehalose, Biomarker, Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213158221001819; https://doaj.org/toc/2213-1582

Access URL: https://doaj.org/article/0108716ede63425b9d0bea7346ef08a6