Regional Intestinal Drug Absorption

Contributors: Gonzalez-Alvarez, Maria Isabel, Dahan, Arik

Subject Terms: bioequivalence, Biopharmaceutics Classification System, in vitro, dissolution test, pravastatin, oral absorption, in silico modeling, GastroPlus, Phoenix WinNonlin, pharmacokinetics, clinical studies, ibuprofen, manometry, gastrointestinal, mechanistic modeling, PBPK, PBBM, disintegration, dissolution, enteric-coated, ICH, quality control, regional intestinal permeability, permeation enhancers, absorption-modifying excipients, oral peptide delivery, intestinal perfusion, pharmaceutical development, controlled release drug product, biopharmaceutics classification system, drug solubility, drug permeability, location-dependent absorption, segregated flow intestinal model (SFM), traditional model (TM), route-dependent intestinal metabolism, first-pass effect, drug-drug interactions, DDI, in vitro in vivo extrapolations, IVIVE, zero-order absorption, first-order absorption, combined zero- and first-order absorption, transit compartment absorption model, in situ perfusion, microdevices, shape, mucoadhesion, colon absorption, nutrient digestion, nutrient absorption, gastrointestinal hormone, postprandial glycaemia, energy intake, region of the gut, obesity, type 2 diabetes, Franz–PAMPA, BCS drugs, biomimetic membrane, Franz cell, passive drug transport, BCS class IV drugs, segmental-dependent intestinal permeability, intestinal absorption, oral drug delivery, biopharmaceutics, physiologically-based pharmacokinetic (PBPK) modeling, furosemide, intestinal permeability, human colon carcinoma cell layer (Caco-2), hierarchical support vector regression (HSVR), drug absorption, drug solubility/dissolution, regional/segmental-dependent permeability and absorption, Medicine and Nursing, Manufacturing industries

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Access URL: https://directory.doabooks.org/handle/20.500.12854/81051
https://mdpi.com/books/pdfview/book/5393

Transmucosal Absorption Enhancers in the Drug Delivery Field

Authors: Maher, Sam, Illum, Lisbeth, Casettari, Luca

Subject Terms: R5-920, RM1-950, chitosan, intestinal epithelial cells, ocular delivery, amphiphilic polymers, cornea, tight junction modulator, cyclodextrin, permeability, gemini surfactant, transferrin, compound 48/80, epithelial permeability, cervicovaginal tumors, nanoparticles, confocal laser scanning microscopy, safety, formulation, salcaprozate sodium, intestinal absorption, FITC-dextran, curcumin, block copolymers, nasal vaccination, whole leaf, brush border, ocular drug delivery, vaccine adjuvant, nanoparticle, nasal delivery, efflux, permeation enhancers, absorption enhancers, nose to brain delivery, small intestine, epithelium, CNS disorders, absorption modifying excipients, insulin, absorption enhancer, gel, intestinal delivery, thermogel system, Caco-2, biocompatibility studies, absorption enhancement, man, PN159, poorly absorbed drug, tryptophan, tight junction, oral macromolecule delivery, penetration enhancer, intestinal permeation enhancers, nanocrystals, simvastatin, nanomedicine, enterocyte, N-dodecyl-?-D-maltoside (DDM), cell-penetrating peptide, quaternization, KLAL, nasal, nasal permeability, transmucosal drug delivery, Caco-2 cells, mast cell activator, penetration enhancers, drug delivery, nose-to-brain, bioenhancer, polymeric micelles, mucoadhesion, cell-penetrating peptide (CPP), simulated intestinal fluid, vaginal delivery, nasal formulation, pharmacokinetic interaction, sodium caprate, clinical trial, transmucosal permeation, drug absorption enhancer, sugar-based surfactants, nanocapsules, imatinib, teriparatide, osteoporosis, hydrophobization, F-actin, combined microsphere, transepithelial electrical resistance, oral delivery, ocular conditions, metabolism, antimicrobial peptide, permeation enhancer, drug administration, antiepileptic drug, amino acid, in vivo studies, sodium cholate (NaC), epithelial transport, preclinical, nose to brain transport, pharmacokinetics, chitosan derivatives, ophthalmology, tight junctions, sheep, cationic functionalization, GLP-1, pulmonary, and liposome, cytochrome P450, claudin, P-glycoprotein, in situ hydrogel, mucoadhesiveness, PTH 1-34, Aloe vera, oral peptides, Medicine and Nursing

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Access URL: https://directory.doabooks.org/handle/20.500.12854/61237
https://www.mdpi.com/books/pdfview/book/1927

Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs, enalaprilat and hexarelin, in rats

Authors: David Dahlgren, Tobias Olander, Markus Sjöblom, Mikael Hedeland, Hans Lennernäs

Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1667-1675 (2021)

Subject Terms: Permeation enhancers, Absorption-modifying excipients, Oral peptide delivery, Intestinal permeability, Intestinal perfusion, Pharmaceutical development, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383521000010; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/1df137de4b5d48ac9f4b8ee8b610534f

Regional Intestinal Drug Permeability and Effects of Permeation Enhancers in Rat

Authors: David Dahlgren, Maria-Jose Cano-Cebrián, Tobias Olander, Mikael Hedeland, Markus Sjöblom, Hans Lennernäs

Source: Pharmaceutics, Vol 12, Iss 3, p 242 (2020)

Subject Terms: regional intestinal permeability, permeation enhancers, absorption-modifying excipients, oral peptide delivery, intestinal perfusion, pharmaceutical development, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/3/242; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/65db05638fd3464494986298dfc65fc2

The In Vivo Effect of Transcellular Permeation Enhancers on the Intestinal Permeability of Two Peptide Drugs Enalaprilat and Hexarelin

Authors: David Dahlgren, Markus Sjöblom, Mikael Hedeland, Hans Lennernäs

Source: Pharmaceutics, Vol 12, Iss 2, p 99 (2020)

Subject Terms: permeation enhancers, absorption-modifying excipients, oral peptide delivery, intestinal permeability, intestinal perfusion, pharmaceutical development, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/2/99; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/b1aa0372921744d8b758b2d62e219ef4

Transmucosal Absorption Enhancers in the Drug Delivery Field

Authors: Sam Maher, Luca Casettari, Lisbeth Illum

Source: Pharmaceutics, Vol 11, Iss 7, p 339 (2019)

Subject Terms: permeation enhancers, absorption modifying excipients, oral delivery, nasal delivery, ocular delivery, vaginal delivery, transmucosal permeation, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/11/7/339; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/d803e30ab0da4e30a6ab3478d01e124e

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