Diversifying Amino Acids and Peptides via Deaminative Reductive Cross-Couplings Leveraging High-Throughput Experimentation

Authors: Twitty, J. Cameron, Hong, Yun, Garcia, Bria, Tsang, Stephanie, Liao, Jennie, Schultz, Danielle M., Hanisak, Jennifer, Zultanski, Susan L., Dion, Amelie, Kalyani, Dipannita

Source: Journal of the American Chemical Society. 145(10):5684-5695

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631882169&indx=1&recIds=ETOCRN631882169

Processes for the preparation of sugammadex

Tunable and Practical Homogeneous Organic Reductants for Cross-Electrophile Coupling

Authors: Charboneau, David J., Huang, Haotian, Barth, Emily L., Germe, Cameron C., Hazari, Nilay, Mercado, Brandon Q., Uehling, Mycah R., Zultanski, Susan L.

Source: Journal of the American Chemical Society. 143(49):21024-21036

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628304632&indx=1&recIds=ETOCRN628304632

Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methodsElectronic supplementary information (ESI) available: Experimental procedures and spectroscopy data for new compounds. See DOI: 10.1039/d1sc01978c

Authors: Klapars, Artis, Chung, John Y. L., Limanto, John, Calabria, Ralph, Campeau, Louis-Charles, Campos, Kevin R., Chen, Wenyong, Dalby, Stephen M., Davis, Tyler A., DiRocco, Daniel A., Hyde, Alan M., Kassim, Amude M., Larsen, Mona Utne, Liu, Guiquan, Maligres, Peter E., Moment, Aaron, Peng, Feng, Ruck, Rebecca T., Shevlin, Michael, Simmons, Bryon L., Song, Zhiguo Jake, Tan, Lushi, Wright, Timothy J., Zultanski, Susan L.

Source: Chemical science. 12(26):9031-9036

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122503530.0x000001&indx=1&recIds=ETOCvdc_100122503530.0x000001

Mechanistic Understanding of a Robust and Scalable Synthesis of Per(6-deoxy-6-halo)cyclodextrins, Versatile Intermediates for Cyclodextrin Modification

Authors: Zultanski, Susan L., Kuhl, Nadine, Zhong, Wendy, Cohen, Ryan D., Reibarkh, Mikhail, Jurica, Jon, Kim, Jungchul, Weisel, Lauren, Ekkati, Anil R., Klapars, Artis

Source: Organic process research & development. 25(3):597-607

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626157967&indx=1&recIds=ETOCRN626157967

Palladium-catalyzed aerobic acetoxylation of benzene using NOx-based redox mediators

Authors: Zultanski, Susan L., Stahl, Shannon S.

Source: In Journal of Organometallic Chemistry 15 September 2015 793:263-268

Asymmetric copper-catalyzed C-N cross-couplings induced by visible light

Authors: Kainz, Quirin M., Matier, Carson D., Bartoszewicz, Agnieszka, Zultanski, Susan L., Peters, Jonas C., Fu, Gregory C.

Source: Science, 2016 Feb 01. 351(6274), 681-684.

Access URL: http://www.jstor.org/stable/24742609

General Principles and Strategies for Salting-Out Informed by the Hofmeister Series

Authors: Hyde, Alan M., Zultanski, Susan L., Waldman, Jacob H., Zhong, Yong-Li, Shevlin, Michael, Peng, Feng

Source: Organic process research & development. 21(9):1355-1370

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN612950013&indx=1&recIds=ETOCRN612950013

Feedstocks to Pharmacophores: Cu-Catalyzed Oxidative Arylation of Inexpensive Alkylarenes Enabling Direct Access to Diarylalkanes

Authors: Vasilopoulos, Aristidis, Zultanski, Susan L., Stahl, Shannon S.

Source: Journal of the American Chemical Society. 139(23):7705-7708

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN611753309&indx=1&recIds=ETOCRN611753309

Practical Synthesis of Amides via Copper/ABNO-Catalyzed Aerobic Oxidative Coupling of Alcohols and Amines

Authors: Zultanski, Susan L., Zhao, Jingyi, Stahl, Shannon S.

Source: Journal of the American Chemical Society. 138(20):6416-6419

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN606500517&indx=1&recIds=ETOCRN606500517

Beyond 20 in the 21st Century: Prospects and Challenges of Non‑canonical Amino Acids in Peptide Drug Discovery.

Authors: Hickey, Jennifer L., Sindhikara, Dan, Zultanski, Susan L., Schultz, Danielle M.

Source: ACS Medicinal Chemistry Letters; 5/11/2023, Vol. 14 Issue 5, p557-565, 9p

Triazoles as γ-secretase modulators

Authors: Fischer, Christian, Zultanski, Susan L., Zhou, Hua, Methot, Joey L., Brown, W. Colby, Mampreian, Dawn M., Schell, Adam J., Shah, Sanjiv, Nuthall, Hugh, Hughes, Bethany L., Smotrov, Nadja, Kenific, Candia M., Cruz, Jonathan C., Walker, Deborah, Bouthillette, Melanie, Nikov, George N., Savage, Dan F., Jeliazkova-Mecheva, Valentina V., Diaz, Damaris, Szewczak, Alexander A., Bays, Nathan, Middleton, Richard E., Munoz, Benito, Shearman, Mark S.

Source: Bioorganic & medicinal chemistry letters. 21(13):4083-4087

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100065490828.0x000001&indx=1&recIds=ETOCvdc_100065490828.0x000001

Homogeneous Organic Electron Donors in Nickel-Catalyzed Reductive Transformations.

Authors: Charboneau, David J., Hazari, Nilay, Huang, Haotian, Uehling, Mycah R., Zultanski, Susan L.

Source: Journal of Organic Chemistry; 6/17/2022, Vol. 87 Issue 12, p7589-7609, 21p

Manufacturing Process Development for Uprifosbuvir (MK-3682): A Green and Sustainable Process for Preparing Penultimate 2′-Deoxy-α-2′-Chloro-β-2′-Methyluridine

Authors: Maligres, Peter E., Peng, Feng, Calabria, Ralph, Campeau, Louis-Charles, Chen, Wenyong, Dormer, Peter G., Green, Meredith, He, Cyndi Qixin, Hyde, Alan M., Klapars, Artis, Larsen, Mona Utne, Limanto, John, Liu, Guiquan, Liu, Yizhou, Moment, Aaron, Nowak, Timothy, Ruck, Rebecca T., Shevlin, Michael, Song, Zhiguo Jake, Tan, Lushi, Tong, Weidong, Waldman, Jacob H., Ye, Honglin, Zhao, Ralph, Zhou, George, Zompa, Michael A., Zultanski, Susan L.

Source: Organic Process Research & Development; September 2022, Vol. 26 Issue: 9 p2728-2738, 11p

Catalytic Asymmetric γ-Alkylation of Carbonyl Compounds via Stereoconvergent Suzuki Cross-Couplings.

Authors: Zultanski, Susan L., Fu, Gregory C.

Source: Journal of the American Chemical Society; October 5 2011, Vol. 133 Issue 39, p15362-15364, 3p

A Widely Applicable Dual Catalytic System for Cross-Electrophile Coupling Enabled by Mechanistic Studies.

Authors: Charboneau, David J., Barth, Emily L., Hazari, Nilay, Uehling, Mycah R., Zultanski, Susan L.

Source: ACS Catalysis; 11/6/2020, Vol. 10 Issue 21, p12642-12656, 15p

Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys

Authors: Fischer, Christian, Zultanski, Susan L., Zhou, Hua, Methot, Joey L., Shah, Sanjiv, Hayashi, Ikuo, Hughes, Bethany L., Moxham, Christopher M., Bays, Nathan W., Smotrov, Nadya, Hill, Armetta D., Pan, Bo-Sheng, Wu, Zhenhua, Moy, Lily Y., Tanga, Flobert, Kenific, Candia, Cruz, Jonathan C., Walker, Deborah, Bouthillette, Melanie, Nikov, George N., Deshmukh, Sujal V., Jeliazkova-Mecheva, Valentina V., Diaz, Damaris, Michener, Maria S., Cook, Jacquelynn J., Munoz, Benito, Shearman, Mark S.

Source: In Bioorganic & Medicinal Chemistry Letters 1 September 2015 25(17):3488-3494

Triazoloamides as potent γ-secretase modulators with reduced hERG liability

Authors: Fischer, Christian, Zultanski, Susan L., Zhou, Hua, Methot, Joey L., Shah, Sanjiv, Nuthall, Hugh, Hughes, Bethany L., Smotrov, Nadja, Hill, Armetta, Szewczak, Alexander A., Moxham, Christopher M., Bays, Nathan, Middleton, Richard E., Munoz, Benito, Shearman, Mark S.

Source: In Bioorganic & Medicinal Chemistry Letters 1 May 2012 22(9):3140-3146

General Principles and Strategies for Salting-Out Informed by the Hofmeister Series

Authors: Hyde, Alan M., Zultanski, Susan L., Waldman, Jacob H., Zhong, Yong-Li, Shevlin, Michael, Peng, Feng

Source: Organic Process Research & Development; 20240101, Issue: Preprints

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